Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 42609525 . G A CCDS13668.1:NM_012105.4:c.487Gtc>Atc_NP_036237.2:p.163V>I Homo sapiens beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6uj0 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 VAL A:163 A:101 0.0 0.0 E -104.2 124.6 0.0 0.0 0.0 HOH
 3.619
 CG1
 O
VAL B:163 B:101 1.0 0.006 E -122.0 133.4 NA NA NA
6uj1 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 VAL A:163 A:101 1.0 0.006 E -130.0 141.5 1.0 0.006 0.0
VAL B:163 B:101 1.0 0.006 E -126.4 140.3 NA NA NA
3zkm 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 VAL A:89 A:101 1.0 0.006 E -126.7 137.1 1.0 0.006 0.0 SO4
HOH
 9.430
4.824
 CG2
C
 O2
O
VAL B:89 B:101 1.0 0.006 E -131.6 136.0 NA NA NA
3zkn 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 VAL A:89 A:101 0.0 0.0 E -130.4 136.5 NA NA NA
VAL B:89 B:101 0.0 0.0 E -126.3 141.0 0.0 0.0 0.0 SO4
HOH
 9.012
4.776
 CG2
C
 O1
O
3zkq 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 VAL A:89 A:101 1.0 0.006 E -127.7 142.0 1.0 0.006 0.0 HOH
 4.134
 CA
 O
3zks 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 VAL A:89 A:101 0.0 0.0 E -119.9 139.4 0.0 0.0 0.0 HOH
 4.150
 CA
 O
4bel 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 VAL A:89 A:101 4.0 0.026 E -124.6 145.6 4.0 0.026 0.0 HOH
 4.040
 CA
 O
VAL B:89 B:101 0.0 0.0 E -123.7 141.2 NA NA NA
4bfb 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 VAL A:89 A:101 2.0 0.013 E -121.9 148.0 2.0 0.013 0.0 HOH
 4.349
 CA
 O
VAL B:89 B:101 0.0 0.0 E -122.7 139.1 NA NA NA
6jsz 1 Q9Y5Z0 100.0 0.0 X-RAY
 2019-08-28 VAL A:89 A:101 1.0 0.006 E -132.1 139.1 1.0 0.006 0.0 HOH
 4.179
 CA
 O
7d5b 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 VAL A:89 A:101 1.0 0.006 E -128.4 140.3 1.0 0.006 0.0 HOH
 4.730
 O
 O
7d5u 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 VAL A:89 A:101 1.0 0.006 E -116.4 146.6 1.0 0.006 0.0 HOH
 4.166
 CA
 O
7n4n 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-10-06 VAL A:89 A:101 1.0 0.006 E -130.2 141.1 1.0 0.006 0.0 HOH
 4.579
 O
 O
3zkg 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 VAL A:89 A:101 1.0 0.006 E -127.6 148.0 1.0 0.006 0.0 HOH
 4.130
 CA
 O
VAL B:89 B:101 1.0 0.006 E -127.8 141.9 NA NA NA
3zki 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 VAL A:89 A:101 1.0 0.006 E -138.2 143.9 1.0 0.006 0.0 HOH
 4.078
 C
 O
VAL B:89 B:101 0.0 0.0 E -123.9 129.4 NA NA NA
3zkx 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 VAL A:89 A:101 0.0 0.0 E -132.1 140.7 0.0 0.0 0.0 HOH
 4.513
 C
 O
3zl7 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 VAL A:89 A:101 2.0 0.013 E -125.1 121.5 2.0 0.013 0.0 HOH
 4.685
 O
 O
3zlq 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-01 VAL A:89 A:101 2.0 0.013 E -127.9 152.5 2.0 0.013 0.0 HOH
 7.526
 CG2
 O
VAL B:89 B:101 1.0 0.006 E -120.9 144.4 1.0 0.006 0.0 HOH
 7.335
 CG2
 O
2ewy 1 Q9Y5Z0 100.0 0.0 X-RAY
 2006-11-07 VAL A:86 A:101 1.0 0.006 E -128.6 147.9 1.0 0.006 0.0 HOH
 6.766
 O
 O
VAL B:86 B:101 1.0 0.006 E -128.6 147.9 NA NA NA
VAL C:86 C:101 0.0 0.0 E -128.7 147.8 NA NA NA
VAL D:86 D:101 0.0 0.0 E -128.6 147.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9y5z0-f1 1 Q9Y5Z0 100.0 0.0 VAL A:163 A:163 1.0 0.006 E -122.2 133.9