Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 42629245 . C A CCDS13668.1:NM_012105.4:c.1295cCc>cAc_NP_036237.2:p.432P>H Homo sapiens beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6uj0 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 PRO A:432 A:370 48.0 0.331 G -60.1 -30.0 48.0 0.331 0.0 HOH
 4.834
 N
 O
PRO B:432 B:370 52.0 0.359 G -64.9 -35.8 NA NA NA
6uj1 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 PRO A:432 A:370 39.0 0.269 T -55.5 -37.0 39.0 0.269 0.0
PRO B:432 B:370 43.0 0.297 G -51.5 -35.0 NA NA NA
3zkm 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:358 A:370 40.0 0.276 T -61.6 -33.7 40.0 0.276 0.0 HOH
 3.185
 CD
 O
PRO B:358 B:370 31.0 0.214 T -59.9 -27.7 NA NA NA
3zkn 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:358 A:370 34.0 0.234 T -58.8 -34.5 NA NA NA
PRO B:358 B:370 43.0 0.297 T -73.6 -28.1 43.0 0.297 0.0 HOH
 6.224
 O
 O
3zkq 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:358 A:370 48.0 0.331 T -56.1 -34.0 48.0 0.331 0.0 HOH
 3.654
 CD
 O
3zks 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:358 A:370 42.0 0.29 T -58.6 -29.1 42.0 0.29 0.0 HOH
 3.156
 CD
 O
4bel 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:358 A:370 55.0 0.379 T -57.3 -34.8 55.0 0.379 0.0 HOH
 2.845
 O
 O
PRO B:358 B:370 54.0 0.372 T -54.5 -43.3 NA NA NA
4bfb 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:358 A:370 57.0 0.393 T -51.3 -33.9 57.0 0.393 0.0 HOH
 2.716
 O
 O
PRO B:358 B:370 54.0 0.372 T -50.0 -42.0 NA NA NA
6jsz 1 Q9Y5Z0 100.0 0.0 X-RAY
 2019-08-28 PRO A:358 A:370 69.0 0.476 T -61.7 -32.7 69.0 0.476 0.0 HOH
 3.465
 CD
 O
7d5b 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 PRO A:358 A:370 54.0 0.372 T -56.1 -33.7 54.0 0.372 0.0 HOH
 3.462
 CD
 O
7d5u 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 PRO A:358 A:370 54.0 0.372 T -56.5 -29.7 54.0 0.372 0.0 HOH
 5.688
 N
 O
7n4n 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-10-06 PRO A:358 A:370 50.0 0.345 T -54.9 -35.6 50.0 0.345 0.0 HOH
 2.702
 HD2
 O
3zkg 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 PRO A:358 A:370 50.0 0.345 T -51.9 -36.5 50.0 0.345 0.0 HOH
 4.897
 CG
 O
PRO B:358 B:370 47.0 0.324 T -58.3 -40.0 NA NA NA
3zki 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 PRO A:358 A:370 57.0 0.393 T -50.2 -37.7 57.0 0.393 0.0 HOH
 6.360
 N
 O
PRO B:358 B:370 36.0 0.248 T -59.1 -37.5 NA NA NA
3zkx 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 PRO A:358 A:370 59.0 0.407 T -55.5 -32.2 59.0 0.407 0.0 HOH
 3.371
 O
 O
3zl7 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 PRO A:358 A:370 60.0 0.414 T -72.8 -28.8 60.0 0.414 0.0
3zlq 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-01 PRO A:358 A:370 59.0 0.407 T -46.2 -43.6 59.0 0.407 0.0 HOH
 6.774
 N
 O
PRO B:358 B:370 48.0 0.331 T -41.0 -51.0 48.0 0.331 0.0
2ewy 1 Q9Y5Z0 100.0 0.0 X-RAY
 2006-11-07 PRO A:355 A:370 54.0 0.372 T -51.9 -53.2 54.0 0.372 0.0 HOH
 7.472
 O
 O
PRO B:355 B:370 56.0 0.386 T -51.9 -53.2 NA NA NA
PRO C:355 C:370 56.0 0.386 T -52.0 -53.2 NA NA NA
PRO D:355 D:370 54.0 0.372 T -51.9 -53.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9y5z0-f1 1 Q9Y5Z0 100.0 0.0 PRO A:432 A:432 51.0 0.352 T -69.6 -19.4