Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 42647334 . C A CCDS13668.1:NM_012105.4:c.1340cCt>cAt_NP_036237.2:p.447P>H Homo sapiens beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6uj0 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 PRO A:447 A:385 67.0 0.462 E -89.8 164.0 67.0 0.462 0.0 HOH
 6.275
 CB
 O
PRO B:447 B:385 63.0 0.434 E -93.1 163.2 NA NA NA
6uj1 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 PRO A:447 A:385 64.0 0.441 -90.2 -167.1 64.0 0.441 0.0
PRO B:447 B:385 69.0 0.476 -79.3 175.2 NA NA NA
3zkm 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:373 A:385 71.0 0.49 E -89.8 158.5 71.0 0.49 0.0 HOH
 2.651
 O
 O
PRO B:373 B:385 70.0 0.483 E -85.7 159.5 NA NA NA
3zkn 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:373 A:385 69.0 0.476 E -87.2 164.7 NA NA NA
PRO B:373 B:385 72.0 0.497 E -89.5 155.9 72.0 0.497 0.0 HOH
 7.112
 C
 O
3zkq 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:373 A:385 78.0 0.538 E -88.9 160.1 78.0 0.538 0.0 HOH
 2.835
 O
 O
3zks 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:373 A:385 76.0 0.524 E -94.7 162.9 76.0 0.524 0.0 HOH
 5.195
 N
 O
4bel 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:373 A:385 71.0 0.49 E -85.1 156.9 71.0 0.49 0.0 HOH
 2.973
 O
 O
PRO B:373 B:385 71.0 0.49 E -87.4 159.6 NA NA NA
4bfb 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:373 A:385 72.0 0.497 E -89.1 150.6 72.0 0.497 0.0 HOH
 5.626
 N
 O
PRO B:373 B:385 79.0 0.545 E -84.9 155.4 NA NA NA
6jsz 1 Q9Y5Z0 100.0 0.0 X-RAY
 2019-08-28 PRO A:373 A:385 74.0 0.51 E -85.1 159.4 74.0 0.51 0.0 HOH
 3.023
 O
 O
7d5b 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 PRO A:373 A:385 70.0 0.483 E -88.8 159.6 70.0 0.483 0.0 HOH
 2.859
 O
 O
7d5u 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 PRO A:373 A:385 79.0 0.545 E -111.9 162.3 79.0 0.545 0.0 HOH
 5.309
 CB
 O
7n4n 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-10-06 PRO A:373 A:385 76.0 0.524 E -88.9 159.9 76.0 0.524 0.0 HOH
 2.722
 O
 O
3zkg 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 PRO A:373 A:385 65.0 0.448 E -91.7 167.7 65.0 0.448 0.0 HOH
 2.612
 O
 O
PRO B:373 B:385 62.0 0.428 E -85.1 167.8 NA NA NA
3zki 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 PRO A:373 A:385 66.0 0.455 E -96.8 174.8 66.0 0.455 0.0 HOH
 3.670
 O
 O
PRO B:373 B:385 63.0 0.434 E -86.1 173.2 NA NA NA
3zkx 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 PRO A:373 A:385 80.0 0.552 E -91.6 160.1 80.0 0.552 0.0 HOH
 3.880
 CD
 O
3zl7 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 PRO A:373 A:385 80.0 0.552 E -87.2 151.2 80.0 0.552 0.0
3zlq 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-01 PRO A:373 A:385 59.0 0.407 E -87.6 166.1 59.0 0.407 0.0 HOH
 7.668
 CG
 O
PRO B:373 B:385 60.0 0.414 E -104.7 164.9 60.0 0.414 0.0 HOH
 9.009
 C
 O
2ewy 1 Q9Y5Z0 100.0 0.0 X-RAY
 2006-11-07 PRO A:370 A:385 60.0 0.414 E -94.7 154.7 60.0 0.414 0.0 HOH
 9.876
 N
 O
PRO B:370 B:385 60.0 0.414 E -94.8 154.7 NA NA NA
PRO C:370 C:385 59.0 0.407 E -94.8 154.7 NA NA NA
PRO D:370 D:385 60.0 0.414 E -94.7 154.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9y5z0-f1 1 Q9Y5Z0 100.0 0.0 PRO A:447 A:447 74.0 0.51 E -87.5 154.7