Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 42647372 . G A CCDS13668.1:NM_012105.4:c.1378Gct>Act_NP_036237.2:p.460A>T Homo sapiens beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6uj0 1 Q9Y5Z0 99.78 0.0 X-RAY
2020-10-07 ALA A:460 NA:NA DO NA DO DO DO NA NA NA
ALA B:460 B:398 153.0 1.0 -88.9 360.0 NA NA NA
6uj1 1 Q9Y5Z0 99.78 0.0 X-RAY
2020-10-07 ALA A:460 NA:NA DO NA DO DO DO NA NA NA
ALA B:460 NA:NA DO NA DO DO DO NA NA NA
3zkm 1 Q9Y5Z0 100.0 0.0 X-RAY
2013-05-29 ALA A:386 NA:NA DO NA DO DO DO NA NA NA
ALA B:386 NA:NA DO NA DO DO DO NA NA NA
3zkn 1 Q9Y5Z0 100.0 0.0 X-RAY
2013-05-29 ALA A:386 NA:NA DO NA DO DO DO NA NA NA
ALA B:386 NA:NA DO NA DO DO DO NA NA NA
3zkq 1 Q9Y5Z0 100.0 0.0 X-RAY
2013-05-29 ALA A:386 A:398 147.0 1.0 -118.2 360.0 147.0 1.0 0.0 HOH
3.621
N
O
3zks 1 Q9Y5Z0 100.0 0.0 X-RAY
2013-05-29 ALA A:386 NA:NA DO NA DO DO DO NA NA NA
4bel 1 Q9Y5Z0 100.0 0.0 X-RAY
2013-05-29 ALA A:386 NA:NA DO NA DO DO DO NA NA NA
ALA B:386 NA:NA DO NA DO DO DO NA NA NA
4bfb 1 Q9Y5Z0 100.0 0.0 X-RAY
2013-05-29 ALA A:386 NA:NA DO NA DO DO DO NA NA NA
ALA B:386 NA:NA DO NA DO DO DO NA NA NA
6jsz 1 Q9Y5Z0 100.0 0.0 X-RAY
2019-08-28 ALA A:386 A:398 144.0 1.0 -162.5 360.0 144.0 1.0 0.0 HOH
3.853
O
O
7d5b 1 Q9Y5Z0 100.0 0.0 X-RAY
2021-03-31 ALA A:386 NA:NA DO NA DO DO DO NA NA NA
7d5u 1 Q9Y5Z0 100.0 0.0 X-RAY
2021-03-31 ALA A:386 NA:NA DO NA DO DO DO NA NA NA
7n4n 1 Q9Y5Z0 100.0 0.0 X-RAY
2021-10-06 ALA A:386 A:398 135.0 1.0 -150.3 360.0 135.0 1.0 0.0 HOH
7.008
HB1
O
3zkg 1 Q9Y5Z0 99.74 0.0 X-RAY
2013-05-29 ALA A:386 NA:NA DO NA DO DO DO NA NA NA
ALA B:386 NA:NA DO NA DO DO DO NA NA NA
3zki 1 Q9Y5Z0 99.74 0.0 X-RAY
2013-05-29 ALA A:386 NA:NA DO NA DO DO DO NA NA NA
ALA B:386 NA:NA DO NA DO DO DO NA NA NA
3zkx 1 Q9Y5Z0 99.74 0.0 X-RAY
2013-05-29 ALA A:386 NA:NA DO NA DO DO DO NA NA NA
3zl7 1 Q9Y5Z0 99.74 0.0 X-RAY
2013-05-29 ALA A:386 NA:NA DO NA DO DO DO NA NA NA
3zlq 1 Q9Y5Z0 99.74 0.0 X-RAY
2013-05-01 ALA A:386 NA:NA DO NA DO DO DO NA NA NA
ALA B:386 NA:NA DO NA DO DO DO NA NA NA
2ewy 1 Q9Y5Z0 100.0 0.0 X-RAY
2006-11-07 ALA A:383 A:398 175.0 NA -107.9 360.0 175.0 NA NA HOH
9.574
CB
O
ALA B:383 B:398 173.0 NA -107.9 360.0 NA NA NA
ALA C:383 C:398 174.0 NA -107.9 360.0 NA NA NA
ALA D:383 D:398 174.0 NA -107.9 360.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9y5z0-f1 1 Q9Y5Z0 100.0 0.0 ALA A:460 A:460 94.0 0.817 -57.9 127.5