Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 34876514 . A C CCDS13627.1:NM_000819.4:c.2950Ttt>Gtt_NP_000810.1:p.984F>V Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1zlx 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 PHE A:177 A:177 0.0 0.0 H -58.8 -54.5 0.0 0.0 0.0 HOH
 3.095
 CB
 O
1zly 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 PHE A:177 A:177 0.0 0.0 H -62.5 -52.2 0.0 0.0 0.0 GRF
DQB
HOH
 6.086
9.481
3.318
 CE2
CZ
CB
 N19
C9
O
1meo 1 P22102 100.0 5e-138 X-RAY
 2002-12-18 PHE A:177 A:177 0.0 0.0 H -64.2 -53.5 0.0 0.0 0.0 PO4
HOH
 8.338
3.918
 CB
CE2
 O3
O
1njs 1 P22102 100.0 5e-138 X-RAY
 2003-06-10 PHE A:177 A:177 0.0 0.0 H -66.1 -49.5 0.0 0.0 0.0 PO4
KEU
HOH
 7.202
9.034
3.331
 CD2
CE2
CB
 O4
F1
O
PHE B:177 B:177 0.0 0.0 H -64.7 -54.0 NA NA NA
1rbm 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 PHE A:177 A:177 0.0 0.0 H -68.1 -51.2 0.0 0.0 0.0 PO4
KT5
HOH
 7.267
8.996
3.394
 CD2
CE2
CB
 O1
F1
O
PHE B:177 B:177 0.0 0.0 H -65.2 -55.0 NA NA NA
1rbq 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 PHE A:177 A:177 0.0 0.0 H -64.7 -52.1 0.0 0.0 0.0 PO4
KEU
HOH
 7.231
9.094
3.339
 CD2
CE2
CB
 O1
F1
O
PHE B:177 B:177 0.0 0.0 H -64.5 -52.3 NA NA NA
PHE C:177 C:177 0.0 0.0 H -63.6 -54.0 NA NA NA
PHE D:177 D:177 0.0 0.0 H -63.0 -54.6 NA NA NA
1rby 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 PHE A:177 A:177 0.0 0.0 H -69.6 -51.6 0.0 0.0 0.0 KEU
GAR
HOH
 9.144
6.207
3.380
 CE2
CE2
CB
 F1
C23
O
PHE B:177 B:177 0.0 0.0 H -66.5 -54.7 NA NA NA
PHE C:177 C:177 0.0 0.0 H -63.7 -52.9 NA NA NA
PHE D:177 D:177 0.0 0.0 H -65.0 -53.3 NA NA NA
1rbz 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 PHE A:177 A:177 0.0 0.0 H -63.7 -51.4 0.0 0.0 0.0 KT5
HOH
 8.137
3.484
 CD2
CB
 OEP
O
PHE B:177 B:177 0.0 0.0 H -61.9 -52.3 NA NA NA
1rc0 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 PHE A:177 A:177 0.0 0.0 H -66.0 -50.8 0.0 0.0 0.0 KT5
HOH
 9.109
5.628
 CE2
CE2
 F1
O
PHE B:177 B:177 0.0 0.0 H -60.7 -54.4 NA NA NA
1rc1 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 PHE A:177 A:177 0.0 0.0 H -61.9 -52.1 0.0 0.0 0.0 PO4
KT3
HOH
 7.080
9.116
3.245
 CD2
CE2
CB
 O1
F1
O
PHE B:177 B:177 0.0 0.0 H -65.1 -50.9 NA NA NA
4ew1 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 PHE A:177 A:177 0.0 0.0 H -63.6 -50.6 0.0 0.0 0.0 PO4
SO4
HOH
 8.234
9.908
3.940
 CB
CD2
CE2
 O3
O3
O
4ew2 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 PHE A:177 A:177 0.0 0.0 H -65.0 -49.1 0.0 0.0 0.0 PO4
HOH
 8.256
3.612
 CD2
CE2
 O3
O
4ew3 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 PHE A:177 A:177 0.0 0.0 H -63.4 -48.8 0.0 0.0 0.0 PO4
HOH
 8.263
3.748
 CD2
CE2
 O3
O
4zyt 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 PHE A:178 A:984 0.0 0.0 H -65.4 -51.0 0.0 0.0 0.0 GAR
3Y9
HOH
 7.176
9.730
3.134
 CD1
CE1
CB
 O8
C29
O
4zyu 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 PHE A:178 A:984 0.0 0.0 H -63.6 -50.9 0.0 0.0 0.0 GAR
3YA
HOH
 7.010
9.215
3.106
 CD1
CE1
CB
 O18
C29
O
4zyv 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 PHE A:178 A:984 0.0 0.0 H -66.6 -48.7 0.0 0.0 0.0 GAR
G71
HOH
 7.100
9.717
3.322
 CD2
CZ
CB
 O16
C29
O
4zyw 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 PHE A:178 A:984 0.0 0.0 H -60.0 -52.6 0.0 0.0 0.0 GAR
G94
HOH
 7.155
9.573
3.168
 CD1
CE1
CB
 O16
C29
O
4zyx 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 PHE A:178 A:984 0.0 0.0 H -71.0 -46.4 0.0 0.0 0.0 GAR
3YB
HOH
 7.186
9.550
3.334
 CD2
CZ
CB
 O18
C29
O
4zyy 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 PHE A:178 A:984 0.0 0.0 H -66.4 -49.0 0.0 0.0 0.0 GAR
3YC
HOH
 7.146
9.518
3.124
 CD1
CE1
CB
 O16
C29
O
4zyz 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 PHE A:178 A:984 0.0 0.0 H -69.7 -47.7 0.0 0.0 0.0 GAR
3YD
HOH
 7.119
9.471
3.282
 CD2
CZ
CB
 O18
C29
O
4zz0 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 PHE A:178 A:984 0.0 0.0 H -72.1 -46.1 0.0 0.0 0.0 GAR
3YE
HOH
 7.159
9.509
3.334
 CD2
CZ
CB
 O18
C29
O
4zz1 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 PHE A:178 A:984 0.0 0.0 H -66.4 -49.9 0.0 0.0 0.0 GAR
3YF
HOH
 7.172
9.484
3.200
 CD1
CE1
CB
 O8
C29
O
4zz2 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 PHE A:178 A:984 0.0 0.0 H -70.0 -48.0 0.0 0.0 0.0 GAR
3YG
HOH
 7.235
9.681
3.333
 CD2
CZ
CB
 O16
C29
O
4zz3 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 PHE A:178 A:984 0.0 0.0 H -74.3 -43.4 0.0 0.0 0.0 4DW
GAR
HOH
 9.796
7.162
5.219
 CZ
CD2
O
 C8
O18
O
7jg0 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 PHE A:178 A:983 0.0 0.0 H -65.4 -53.3 0.0 0.0 0.0 GAR
V97
HOH
 6.575
9.164
3.189
 CE2
CZ
CB
 H2
C30
O
7jg3 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 PHE A:178 A:984 0.0 0.0 H -66.1 -52.1 0.0 0.0 0.0 GAR
V9A
HOH
 6.544
8.849
3.249
 CE2
CZ
CB
 H2
C30
O
7jg4 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 PHE A:178 A:984 0.0 0.0 H -70.7 -49.7 0.0 0.0 0.0 GAR
V9V
NA
HOH
 6.510
9.337
9.836
3.272
 CE2
CZ
CE2
CB
 H2
C29
NA
O
5j9f 1 P22102 99.51 4e-137 X-RAY
 2016-08-10 PHE A:178 A:984 0.0 0.0 H -69.5 -45.1 0.0 0.0 0.0 GAR
83A
HOH
 7.160
9.608
3.226
 CD2
CE2
CB
 O16
C8
O
1mej 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 PHE A:188 B:177 1.0 0.005 H -67.1 -50.6 1.0 0.005 0.0 PO4
HOH
 7.580
3.357
 CD1
CB
 O4
O
PHE B:188 A:177 1.0 0.005 H -70.8 -51.3 NA NA NA
PHE C:188 C:177 1.0 0.005 H -67.9 -51.0 NA NA NA
1men 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 PHE A:188 A:177 1.0 0.005 H -67.5 -49.5 1.0 0.005 0.0 GAR
HOH
 7.184
3.177
 CD2
CB
 O8
O
PHE B:188 B:177 0.0 0.0 H -64.1 -51.5 NA NA NA
PHE C:188 C:177 0.0 0.0 H -71.8 -48.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22102-f1 1 P22102 100.0 0.0 PHE A:984 A:984 0.0 0.0 H -67.1 -46.5