Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 34876532 . A C CCDS13627.1:NM_000819.4:c.2932Tta>Gta_NP_000810.1:p.978L>V Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1zlx 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 LEU A:171 A:171 117.0 0.688 H -65.5 -33.7 117.0 0.688 0.0 HOH
 2.779
 O
 O
1zly 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 LEU A:171 A:171 116.0 0.682 H -60.4 -36.9 116.0 0.682 0.0 GRF
HOH
 7.925
2.816
 N
O
 O3
O
1meo 1 P22102 100.0 5e-138 X-RAY
 2002-12-18 LEU A:171 A:171 127.0 0.747 H -61.5 -37.5 127.0 0.747 0.0 PO4
SO4
HOH
 8.642
6.452
2.770
 N
CD1
O
 O2
O1
O
1njs 1 P22102 100.0 5e-138 X-RAY
 2003-06-10 LEU A:171 A:171 118.0 0.694 H -57.6 -40.2 118.0 0.694 0.0 PO4
PO4
HOH
 9.335
6.542
2.656
 N
CD1
O
 O2
O2
O
LEU B:171 B:171 92.0 0.541 H -58.9 -41.8 NA NA NA
1rbm 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 LEU A:171 A:171 115.0 0.676 H -57.8 -38.1 115.0 0.676 0.0 PO4
PO4
HOH
 9.582
6.574
2.782
 N
CD1
O
 O3
O4
O
LEU B:171 B:171 88.0 0.518 H -60.1 -36.8 NA NA NA
1rbq 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 LEU A:171 A:171 115.0 0.676 H -55.2 -38.9 115.0 0.676 0.0 PO4
PO4
HOH
 9.463
6.495
2.883
 N
CD1
O
 O3
O1
O
LEU B:171 B:171 114.0 0.671 H -57.4 -37.2 NA NA NA
LEU C:171 C:171 91.0 0.535 H -59.3 -40.5 NA NA NA
LEU D:171 D:171 92.0 0.541 H -57.9 -38.5 NA NA NA
1rby 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 LEU A:171 A:171 120.0 0.706 H -61.3 -34.9 120.0 0.706 0.0 GAR
HOH
 7.759
2.805
 N
O
 O6
O
LEU B:171 B:171 116.0 0.682 H -61.0 -36.8 NA NA NA
LEU C:171 C:171 88.0 0.518 H -61.5 -37.6 NA NA NA
LEU D:171 D:171 95.0 0.559 H -60.7 -37.4 NA NA NA
1rbz 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 LEU A:171 A:171 114.0 0.671 H -61.8 -35.9 114.0 0.671 0.0 KT5
HOH
 7.169
2.769
 N
O
 OEF
O
LEU B:171 B:171 106.0 0.624 H -58.1 -41.1 NA NA NA
1rc0 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 LEU A:171 A:171 95.0 0.559 H -60.0 -40.6 95.0 0.559 0.0 HOH
 2.554
 O
 O
LEU B:171 B:171 116.0 0.682 H -57.4 -39.6 NA NA NA
1rc1 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 LEU A:171 A:171 115.0 0.676 H -57.7 -38.8 115.0 0.676 0.0 PO4
HOH
 9.436
2.708
 N
O
 O3
O
LEU B:171 B:171 103.0 0.606 H -60.6 -37.6 NA NA NA
4ew1 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 LEU A:171 A:171 124.0 0.729 H -61.7 -38.6 124.0 0.729 0.0 PO4
SO4
SO4
HOH
 8.573
6.554
8.461
2.706
 N
CD1
N
O
 O1
O2
O3
O
4ew2 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 LEU A:171 A:171 128.0 0.753 H -60.8 -39.1 128.0 0.753 0.0 PO4
SO4
HOH
 8.667
6.467
2.764
 N
CD1
O
 O1
O4
O
4ew3 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 LEU A:171 A:171 125.0 0.735 H -63.0 -36.5 125.0 0.735 0.0 PO4
SO4
HOH
 8.633
6.381
2.652
 N
CD1
O
 O1
O4
O
4zyt 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 LEU A:172 A:978 112.0 0.659 H -60.2 -37.5 112.0 0.659 0.0 GAR
HOH
 8.096
2.752
 N
O
 O6
O
4zyu 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 LEU A:172 A:978 114.0 0.671 H -60.3 -36.9 114.0 0.671 0.0 GAR
HOH
 7.977
2.707
 N
O
 O6
O
4zyv 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 LEU A:172 A:978 120.0 0.706 H -62.0 -34.6 120.0 0.706 0.0 GAR
HOH
 7.975
2.720
 N
O
 O6
O
4zyw 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 LEU A:172 A:978 119.0 0.7 H -61.6 -36.2 119.0 0.7 0.0 GAR
HOH
 8.075
2.682
 N
O
 O6
O
4zyx 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 LEU A:172 A:978 113.0 0.665 H -60.1 -38.0 113.0 0.665 0.0 GAR
HOH
 8.012
2.707
 N
O
 O6
O
4zyy 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 LEU A:172 A:978 117.0 0.688 H -60.4 -37.2 117.0 0.688 0.0 GAR
HOH
 8.015
2.699
 N
O
 O6
O
4zyz 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 LEU A:172 A:978 118.0 0.694 H -59.8 -38.6 118.0 0.694 0.0 GAR
HOH
 8.055
2.710
 N
O
 O6
O
4zz0 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 LEU A:172 A:978 114.0 0.671 H -60.2 -38.5 114.0 0.671 0.0 GAR
HOH
 8.185
2.720
 N
O
 O6
O
4zz1 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 LEU A:172 A:978 117.0 0.688 H -60.7 -36.8 117.0 0.688 0.0 GAR
HOH
 8.117
2.722
 N
O
 O6
O
4zz2 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 LEU A:172 A:978 118.0 0.694 H -61.1 -36.4 118.0 0.694 0.0 GAR
HOH
 8.102
2.727
 N
O
 O6
O
4zz3 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 LEU A:172 A:978 111.0 0.653 H -65.7 -30.6 111.0 0.653 0.0 GAR
HOH
 8.029
2.695
 N
O
 O6
O
7jg0 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 LEU A:172 A:977 118.0 0.694 H -56.3 -33.5 118.0 0.694 0.0 GAR
HOH
 7.033
2.718
 N
O
 HO6
O
7jg3 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 LEU A:172 A:978 118.0 0.694 H -62.3 -33.3 118.0 0.694 0.0 GAR
HOH
 7.165
2.734
 N
O
 HO6
O
7jg4 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 LEU A:172 A:978 115.0 0.676 H -69.3 -31.2 115.0 0.676 0.0 GAR
HOH
 7.101
2.793
 N
O
 HO6
O
5j9f 1 P22102 99.51 4e-137 X-RAY
 2016-08-10 LEU A:172 A:978 120.0 0.706 H -64.3 -33.2 120.0 0.706 0.0 GAR
HOH
 7.996
2.742
 N
O
 O6
O
1mej 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 LEU A:182 B:171 108.0 0.635 H -64.5 -32.0 108.0 0.635 0.0 PO4
HOH
 9.803
2.772
 N
O
 O2
O
LEU B:182 A:171 116.0 0.682 H -62.8 -33.3 NA NA NA
LEU C:182 C:171 113.0 0.665 H -67.0 -28.6 NA NA NA
1men 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 LEU A:182 A:171 117.0 0.688 H -59.9 -39.4 117.0 0.688 0.0 GAR
HOH
 7.682
3.447
 N
CB
 O6
O
LEU B:182 B:171 107.0 0.629 H -63.1 -39.1 NA NA NA
LEU C:182 C:171 113.0 0.665 H -58.9 -37.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22102-f1 1 P22102 100.0 0.0 LEU A:978 A:978 120.0 0.706 H -62.9 -39.5