Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr21 | 34876538 | . | C | A | CCDS13627.1:NM_000819.4:c.2926Gta>Tta_NP_000810.1:p.976V>L | Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1zlx | 1 | P22102 | 100.0 | 3e-138 |
X-RAY |
2005-08-23 | VAL | A:169 | A:169 | 0.0 | 0.0 | H | -69.6 | -32.9 | 0.0 | 0.0 | 0.0 |
HOH |
3.712 |
CB |
O |
||
| 1zly | 1 | P22102 | 100.0 | 3e-138 |
X-RAY |
2005-08-23 | VAL | A:169 | A:169 | 0.0 | 0.0 | H | -67.6 | -33.8 | 0.0 | 0.0 | 0.0 |
GRF HOH |
6.265 3.659 |
CG1 CB |
O3 O |
||
| 1meo | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2002-12-18 | VAL | A:169 | A:169 | 0.0 | 0.0 | H | -68.0 | -36.8 | 0.0 | 0.0 | 0.0 |
PO4 SO4 HOH |
9.952 7.678 3.500 |
O N CG1 |
O2 O1 O |
||
| 1njs | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2003-06-10 | VAL | A:169 | A:169 | 0.0 | 0.0 | H | -67.6 | -37.7 | 0.0 | 0.0 | 0.0 |
PO4 PO4 KEU HOH |
9.174 7.653 9.461 3.662 |
C N CG1 CB |
O1 O4 F O |
||
| VAL | B:169 | B:169 | 0.0 | 0.0 | H | -63.6 | -38.0 | NA | NA | NA | |||||||||||||
| 1rbm | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | VAL | A:169 | A:169 | 0.0 | 0.0 | H | -68.6 | -36.0 | 0.0 | 0.0 | 0.0 |
PO4 PO4 KT5 HOH |
9.518 7.821 9.500 3.630 |
C N CG1 CB |
O4 O4 F3 O |
||
| VAL | B:169 | B:169 | 0.0 | 0.0 | H | -67.3 | -37.8 | NA | NA | NA | |||||||||||||
| 1rbq | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | VAL | A:169 | A:169 | 0.0 | 0.0 | H | -72.2 | -38.0 | 0.0 | 0.0 | 0.0 |
PO4 PO4 KEU HOH |
9.324 7.760 9.321 3.479 |
C N CG1 CG1 |
O4 O1 F O |
||
| VAL | B:169 | B:169 | 0.0 | 0.0 | H | -70.0 | -38.6 | NA | NA | NA | |||||||||||||
| VAL | C:169 | C:169 | 0.0 | 0.0 | H | -66.7 | -38.9 | NA | NA | NA | |||||||||||||
| VAL | D:169 | D:169 | 0.0 | 0.0 | H | -64.5 | -40.5 | NA | NA | NA | |||||||||||||
| 1rby | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | VAL | A:169 | A:169 | 0.0 | 0.0 | H | -69.0 | -37.6 | 0.0 | 0.0 | 0.0 |
KEU GAR HOH |
9.368 5.704 3.665 |
CG1 CG1 CB |
F O8 O |
||
| VAL | B:169 | B:169 | 0.0 | 0.0 | H | -67.3 | -38.9 | NA | NA | NA | |||||||||||||
| VAL | C:169 | C:169 | 0.0 | 0.0 | H | -66.4 | -37.2 | NA | NA | NA | |||||||||||||
| VAL | D:169 | D:169 | 0.0 | 0.0 | H | -68.0 | -37.5 | NA | NA | NA | |||||||||||||
| 1rbz | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | VAL | A:169 | A:169 | 0.0 | 0.0 | H | -65.0 | -35.5 | 0.0 | 0.0 | 0.0 |
KT5 HOH |
5.421 3.496 |
CG1 CB |
OEF O |
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| VAL | B:169 | B:169 | 0.0 | 0.0 | H | -68.1 | -35.6 | NA | NA | NA | |||||||||||||
| 1rc0 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | VAL | A:169 | A:169 | 0.0 | 0.0 | H | -65.6 | -37.5 | 0.0 | 0.0 | 0.0 |
KT5 HOH |
9.299 3.537 |
CG1 CB |
F3 O |
||
| VAL | B:169 | B:169 | 0.0 | 0.0 | H | -67.2 | -37.0 | NA | NA | NA | |||||||||||||
| 1rc1 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | VAL | A:169 | A:169 | 0.0 | 0.0 | H | -65.7 | -40.2 | 0.0 | 0.0 | 0.0 |
PO4 KT3 HOH |
8.951 9.273 4.676 |
C CG1 CG2 |
O4 F3 O |
||
| VAL | B:169 | B:169 | 0.0 | 0.0 | H | -69.6 | -38.7 | NA | NA | NA | |||||||||||||
| 4ew1 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2013-07-31 | VAL | A:169 | A:169 | 0.0 | 0.0 | H | -67.5 | -36.9 | 0.0 | 0.0 | 0.0 |
PO4 SO4 SO4 SO4 HOH |
9.916 7.658 5.553 8.389 3.562 |
O N CG1 CG1 CG1 |
O1 O4 O3 O3 O |
||
| 4ew2 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2013-07-31 | VAL | A:169 | A:169 | 0.0 | 0.0 | H | -69.3 | -35.0 | 0.0 | 0.0 | 0.0 |
PO4 SO4 SO4 HOH |
9.998 7.684 8.360 3.541 |
O N CG1 CG1 |
O1 O4 O3 O |
||
| 4ew3 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2013-07-31 | VAL | A:169 | A:169 | 0.0 | 0.0 | H | -66.7 | -34.3 | 0.0 | 0.0 | 0.0 |
PO4 SO4 SO4 HOH |
9.929 7.643 8.282 3.521 |
O N CG1 CG1 |
O1 O4 O3 O |
||
| 4zyt | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | VAL | A:170 | A:976 | 0.0 | 0.0 | H | -69.5 | -33.3 | 0.0 | 0.0 | 0.0 |
GAR HOH |
5.971 3.486 |
CG1 CB |
O6 O |
||
| 4zyu | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | VAL | A:170 | A:976 | 0.0 | 0.0 | H | -69.4 | -33.3 | 0.0 | 0.0 | 0.0 |
GAR HOH |
6.075 3.644 |
CG1 CB |
O6 O |
||
| 4zyv | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | VAL | A:170 | A:976 | 0.0 | 0.0 | H | -68.8 | -34.8 | 0.0 | 0.0 | 0.0 |
GAR HOH |
5.972 3.612 |
CG1 CB |
O6 O |
||
| 4zyw | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | VAL | A:170 | A:976 | 0.0 | 0.0 | H | -66.5 | -33.8 | 0.0 | 0.0 | 0.0 |
GAR HOH |
5.925 3.549 |
CG1 CB |
O6 O |
||
| 4zyx | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | VAL | A:170 | A:976 | 0.0 | 0.0 | H | -69.8 | -32.4 | 0.0 | 0.0 | 0.0 |
GAR HOH |
5.974 3.469 |
CG1 CB |
O6 O |
||
| 4zyy | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | VAL | A:170 | A:976 | 0.0 | 0.0 | H | -71.6 | -31.9 | 0.0 | 0.0 | 0.0 |
GAR HOH |
5.883 3.520 |
CG1 CG1 |
O6 O |
||
| 4zyz | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | VAL | A:170 | A:976 | 0.0 | 0.0 | H | -68.0 | -33.0 | 0.0 | 0.0 | 0.0 |
GAR HOH |
5.971 3.485 |
CG1 CB |
O6 O |
||
| 4zz0 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | VAL | A:170 | A:976 | 0.0 | 0.0 | H | -68.8 | -32.3 | 0.0 | 0.0 | 0.0 |
GAR HOH |
6.021 3.449 |
CG1 CB |
O6 O |
||
| 4zz1 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2015-12-16 | VAL | A:170 | A:976 | 0.0 | 0.0 | H | -66.9 | -35.6 | 0.0 | 0.0 | 0.0 |
GAR HOH |
5.920 3.458 |
CG1 CB |
O6 O |
||
| 4zz2 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2015-12-16 | VAL | A:170 | A:976 | 0.0 | 0.0 | H | -68.2 | -34.5 | 0.0 | 0.0 | 0.0 |
GAR HOH |
5.944 3.476 |
CG1 CB |
O6 O |
||
| 4zz3 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2015-12-16 | VAL | A:170 | A:976 | 0.0 | 0.0 | H | -68.3 | -35.5 | 0.0 | 0.0 | 0.0 |
GAR HOH |
6.163 4.648 |
CG1 CG2 |
O8 O |
||
| 7jg0 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2021-03-31 | VAL | A:170 | A:975 | 0.0 | 0.0 | H | -65.1 | -36.5 | 0.0 | 0.0 | 0.0 |
GAR HOH |
5.422 3.627 |
CG1 CB |
HO6 O |
||
| 7jg3 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2021-03-31 | VAL | A:170 | A:976 | 0.0 | 0.0 | H | -61.9 | -35.7 | 0.0 | 0.0 | 0.0 |
GAR HOH |
5.377 3.493 |
CG1 CB |
HO6 O |
||
| 7jg4 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2021-03-31 | VAL | A:170 | A:976 | 0.0 | 0.0 | H | -66.2 | -42.4 | 0.0 | 0.0 | 0.0 |
GAR HOH |
5.364 3.587 |
CG1 CB |
HO6 O |
||
| 5j9f | 1 | P22102 | 99.51 | 4e-137 |
X-RAY |
2016-08-10 | VAL | A:170 | A:976 | 0.0 | 0.0 | H | -65.6 | -36.1 | 0.0 | 0.0 | 0.0 |
GAR HOH |
5.980 3.537 |
CG1 CB |
O6 O |
||
| 1mej | 1 | P22102 | 100.0 | 3e-136 |
X-RAY |
2002-12-18 | VAL | A:180 | B:169 | 0.0 | 0.0 | H | -68.5 | -33.8 | 0.0 | 0.0 | 0.0 |
PO4 HOH |
9.629 3.715 |
C CB |
O1 O |
||
| VAL | B:180 | A:169 | 0.0 | 0.0 | H | -71.3 | -30.5 | NA | NA | NA | |||||||||||||
| VAL | C:180 | C:169 | 0.0 | 0.0 | H | -68.7 | -31.4 | NA | NA | NA | |||||||||||||
| 1men | 1 | P22102 | 100.0 | 3e-136 |
X-RAY |
2002-12-18 | VAL | A:180 | A:169 | 0.0 | 0.0 | H | -69.3 | -36.5 | 0.0 | 0.0 | 0.0 |
GAR HOH |
5.793 4.676 |
CG1 N |
O6 O |
||
| VAL | B:180 | B:169 | 0.0 | 0.0 | H | -67.3 | -34.1 | NA | NA | NA | |||||||||||||
| VAL | C:180 | C:169 | 0.0 | 0.0 | H | -67.3 | -36.4 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p22102-f1 | 1 | P22102 | 100.0 | 0.0 | VAL | A:976 | A:976 | 0.0 | 0.0 | H | -62.0 | -41.1 | |