Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 34876544 . C A CCDS13627.1:NM_000819.4:c.2920Gaa>Taa_NP_000810.1:p.974E>* Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1zlx 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 GLU A:167 A:167 140.0 0.737 H -62.9 -44.9 140.0 0.737 0.0 HOH
 2.538
 OE1
 O
1zly 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 GLU A:167 A:167 137.0 0.721 H -66.8 -41.9 137.0 0.721 0.0 GRF
HOH
 7.589
2.792
 N
O
 O3
O
1meo 1 P22102 100.0 5e-138 X-RAY
 2002-12-18 GLU A:167 A:167 128.0 0.674 H -64.1 -39.1 128.0 0.674 0.0 PO4
SO4
HOH
 9.968
6.094
2.890
 O
OE1
O
 O2
O4
O
1njs 1 P22102 100.0 5e-138 X-RAY
 2003-06-10 GLU A:167 A:167 116.0 0.611 H -63.8 -42.6 116.0 0.611 0.0 PO4
PO4
HOH
 7.799
6.561
2.553
 OE2
CB
OE1
 O2
O3
O
GLU B:167 B:167 99.0 0.521 H -63.7 -42.4 NA NA NA
1rbm 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 GLU A:167 A:167 114.0 0.6 H -63.9 -42.2 114.0 0.6 0.0 PO4
PO4
HOH
 7.920
6.427
2.466
 OE2
CB
OE1
 O3
O3
O
GLU B:167 B:167 96.0 0.505 H -62.5 -42.7 NA NA NA
1rbq 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 GLU A:167 A:167 116.0 0.611 H -63.7 -41.4 116.0 0.611 0.0 PO4
PO4
HOH
 7.806
6.690
2.561
 OE2
CB
O
 O3
O2
O
GLU B:167 B:167 118.0 0.621 H -60.9 -41.5 NA NA NA
GLU C:167 C:167 102.0 0.537 H -58.5 -43.4 NA NA NA
GLU D:167 D:167 104.0 0.547 H -63.8 -43.5 NA NA NA
1rby 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 GLU A:167 A:167 116.0 0.611 H -65.6 -38.9 116.0 0.611 0.0 GAR
HOH
 7.291
2.605
 OE2
OE1
 O17
O
GLU B:167 B:167 114.0 0.6 H -58.9 -42.2 NA NA NA
GLU C:167 C:167 103.0 0.542 H -55.6 -43.2 NA NA NA
GLU D:167 D:167 108.0 0.568 H -60.4 -42.0 NA NA NA
1rbz 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 GLU A:167 A:167 106.0 0.558 H -58.7 -42.9 106.0 0.558 0.0 KT5
HOH
 6.581
2.604
 N
OE1
 OEF
O
GLU B:167 B:167 104.0 0.547 H -64.2 -39.8 NA NA NA
1rc0 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 GLU A:167 A:167 106.0 0.558 H -60.4 -44.1 106.0 0.558 0.0 HOH
 2.970
 OE1
 O
GLU B:167 B:167 109.0 0.574 H -59.4 -45.0 NA NA NA
1rc1 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 GLU A:167 A:167 119.0 0.626 H -67.1 -36.9 119.0 0.626 0.0 PO4
HOH
 7.838
2.465
 OE2
OE1
 O3
O
GLU B:167 B:167 104.0 0.547 H -64.3 -41.4 NA NA NA
4ew1 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 GLU A:167 A:167 127.0 0.668 H -59.6 -43.9 127.0 0.668 0.0 SO4
SO4
HOH
 7.402
8.032
2.553
 N
N
OE1
 O3
O2
O
4ew2 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 GLU A:167 A:167 NA NA NA NA NA NA NA NA PO4
SO4
HOH
 8.414
7.924
2.697
 OE2
N
OE1
 O1
O2
O
4ew3 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 GLU A:167 A:167 121.0 0.637 H -52.4 -54.3 121.0 0.637 0.0 SO4
SO4
HOH
 5.154
7.898
2.989
 OE1
N
OE1
 O1
O2
O
4zyt 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 GLU A:168 A:974 137.0 0.721 H -61.6 -45.6 137.0 0.721 0.0 GAR
HOH
 7.538
2.698
 N
OE1
 O6
O
4zyu 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 GLU A:168 A:974 136.0 0.716 H -61.6 -47.3 136.0 0.716 0.0 GAR
HOH
 7.648
2.593
 N
OE1
 O6
O
4zyv 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 GLU A:168 A:974 136.0 0.716 H -62.2 -47.2 136.0 0.716 0.0 GAR
HOH
 7.531
2.703
 N
OE1
 O6
O
4zyw 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 GLU A:168 A:974 140.0 0.737 H -63.2 -45.7 140.0 0.737 0.0 GAR
HOH
 7.517
2.736
 N
O
 O6
O
4zyx 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 GLU A:168 A:974 136.0 0.716 H -60.4 -45.2 136.0 0.716 0.0 GAR
HOH
 7.507
2.683
 N
OE1
 O6
O
4zyy 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 GLU A:168 A:974 136.0 0.716 H -62.1 -46.8 136.0 0.716 0.0 GAR
HOH
 7.507
2.624
 N
OE1
 O6
O
4zyz 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 GLU A:168 A:974 135.0 0.711 H -60.6 -43.8 135.0 0.711 0.0 GAR
HOH
 7.547
2.681
 N
OE1
 O6
O
4zz0 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 GLU A:168 A:974 136.0 0.716 H -61.5 -44.8 136.0 0.716 0.0 GAR
HOH
 7.584
2.701
 N
OE1
 O6
O
4zz1 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 GLU A:168 A:974 135.0 0.711 H -60.8 -45.2 135.0 0.711 0.0 GAR
HOH
 7.479
2.697
 N
OE1
 O6
O
4zz2 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 GLU A:168 A:974 136.0 0.716 H -60.1 -44.7 136.0 0.716 0.0 GAR
HOH
 7.502
2.686
 N
OE1
 O6
O
4zz3 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 GLU A:168 A:974 135.0 0.711 H -62.5 -40.5 135.0 0.711 0.0 GAR
HOH
 7.959
3.185
 N
OE2
 O6
O
7jg0 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 GLU A:168 A:973 140.0 0.737 H -64.2 -47.2 140.0 0.737 0.0 GAR
HOH
 6.967
2.785
 N
O
 HO6
O
7jg3 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 GLU A:168 A:974 138.0 0.726 H -64.3 -45.9 138.0 0.726 0.0 GAR
HOH
 7.206
2.721
 N
OE1
 HO6
O
7jg4 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 GLU A:168 A:974 143.0 0.753 H -60.8 -44.7 143.0 0.753 0.0 GAR
HOH
 7.324
2.700
 N
O
 HO6
O
5j9f 1 P22102 99.51 4e-137 X-RAY
 2016-08-10 GLU A:168 A:974 135.0 0.711 H -64.6 -46.1 135.0 0.711 0.0 GAR
HOH
 7.551
2.684
 N
OE1
 O6
O
1mej 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 GLU A:178 B:167 128.0 0.674 H -60.7 -46.7 128.0 0.674 0.0 HOH
 2.638
 OE2
 O
GLU B:178 A:167 128.0 0.674 H -63.3 -42.0 NA NA NA
GLU C:178 C:167 130.0 0.684 H -68.9 -36.1 NA NA NA
1men 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 GLU A:178 A:167 123.0 0.647 H -65.8 -46.3 123.0 0.647 0.0 GAR
HOH
 7.711
5.448
 N
O
 O6
O
GLU B:178 B:167 127.0 0.668 H -62.9 -45.3 NA NA NA
GLU C:178 C:167 119.0 0.626 H -60.8 -41.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22102-f1 1 P22102 100.0 0.0 GLU A:974 A:974 105.0 0.553 H -65.9 -34.8