Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 34876553 . T A CCDS13627.1:NM_000819.4:c.2911Act>Tct_NP_000810.1:p.971T>S Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1zlx 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 THR A:164 A:164 53.0 0.379 H -73.3 -40.6 53.0 0.379 0.0 HOH
 2.857
 O
 O
1zly 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 THR A:164 A:164 53.0 0.379 H -73.8 -37.6 53.0 0.379 0.0 HOH
 2.845
 O
 O
1meo 1 P22102 100.0 5e-138 X-RAY
 2002-12-18 THR A:164 A:164 52.0 0.371 H -67.4 -40.4 52.0 0.371 0.0 SO4
HOH
 4.595
2.618
 O
O
 O4
O
1njs 1 P22102 100.0 5e-138 X-RAY
 2003-06-10 THR A:164 A:164 65.0 0.464 H -71.4 -34.4 65.0 0.464 0.0 PO4
HOH
 4.586
2.654
 O
O
 O3
O
THR B:164 B:164 62.0 0.443 H -69.9 -43.6 NA NA NA
1rbm 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 THR A:164 A:164 65.0 0.464 H -69.0 -39.9 65.0 0.464 0.0 PO4
HOH
 4.654
2.600
 O
O
 O3
O
THR B:164 B:164 62.0 0.443 H -71.4 -43.9 NA NA NA
1rbq 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 THR A:164 A:164 64.0 0.457 H -69.0 -40.5 64.0 0.457 0.0 PO4
HOH
 4.756
2.562
 O
O
 O2
O
THR B:164 B:164 62.0 0.443 H -71.0 -37.7 NA NA NA
THR C:164 C:164 63.0 0.45 H -73.8 -46.8 NA NA NA
THR D:164 D:164 63.0 0.45 H -72.3 -43.9 NA NA NA
1rby 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 THR A:164 A:164 62.0 0.443 H -70.6 -39.1 62.0 0.443 0.0 HOH
 2.675
 O
 O
THR B:164 B:164 63.0 0.45 H -67.6 -39.9 NA NA NA
THR C:164 C:164 64.0 0.457 H -73.3 -44.4 NA NA NA
THR D:164 D:164 62.0 0.443 H -70.8 -45.6 NA NA NA
1rbz 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 THR A:164 A:164 62.0 0.443 H -70.0 -40.3 62.0 0.443 0.0 KT5
HOH
 9.582
2.728
 O
O
 OEF
O
THR B:164 B:164 63.0 0.45 H -73.0 -42.1 NA NA NA
1rc0 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 THR A:164 A:164 63.0 0.45 H -72.2 -42.5 63.0 0.45 0.0 HOH
 2.626
 O
 O
THR B:164 B:164 63.0 0.45 H -72.5 -39.1 NA NA NA
1rc1 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 THR A:164 A:164 65.0 0.464 H -69.2 -40.4 65.0 0.464 0.0 HOH
 2.801
 O
 O
THR B:164 B:164 60.0 0.429 H -72.5 -44.1 NA NA NA
4ew1 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 THR A:164 A:164 52.0 0.371 H -74.5 -35.1 52.0 0.371 0.0 SO4
SO4
HOH
 4.608
8.481
2.644
 O
N
O
 O1
O2
O
4ew2 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 THR A:164 A:164 69.0 0.493 H -75.7 -35.6 69.0 0.493 0.0 SO4
SO4
HOH
 4.634
8.315
2.595
 O
N
O
 O1
O2
O
4ew3 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 THR A:164 A:164 45.0 0.321 H -74.8 -34.6 45.0 0.321 0.0 SO4
SO4
HOH
 4.660
8.226
2.596
 O
N
O
 O1
O2
O
4zyt 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 THR A:165 A:971 52.0 0.371 H -78.2 -34.0 52.0 0.371 0.0 HOH
 2.774
 O
 O
4zyu 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 THR A:165 A:971 52.0 0.371 H -80.2 -33.8 52.0 0.371 0.0 HOH
 2.752
 O
 O
4zyv 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 THR A:165 A:971 52.0 0.371 H -74.3 -38.4 52.0 0.371 0.0 HOH
 2.740
 O
 O
4zyw 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 THR A:165 A:971 55.0 0.393 H -76.7 -35.7 55.0 0.393 0.0 HOH
 2.751
 O
 O
4zyx 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 THR A:165 A:971 51.0 0.364 H -78.8 -36.8 51.0 0.364 0.0 HOH
 2.789
 O
 O
4zyy 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 THR A:165 A:971 51.0 0.364 H -77.1 -35.3 51.0 0.364 0.0 HOH
 2.778
 O
 O
4zyz 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 THR A:165 A:971 51.0 0.364 H -79.2 -36.0 51.0 0.364 0.0 HOH
 2.805
 O
 O
4zz0 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 THR A:165 A:971 50.0 0.357 H -79.0 -35.4 50.0 0.357 0.0 HOH
 2.802
 O
 O
4zz1 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 THR A:165 A:971 53.0 0.379 H -77.9 -36.6 53.0 0.379 0.0 HOH
 2.791
 O
 O
4zz2 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 THR A:165 A:971 53.0 0.379 H -78.1 -37.1 53.0 0.379 0.0 HOH
 2.808
 O
 O
4zz3 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 THR A:165 A:971 52.0 0.371 H -77.0 -38.7 52.0 0.371 0.0 HOH
 6.439
 O
 O
7jg0 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 THR A:165 A:970 54.0 0.386 H -73.7 -37.2 54.0 0.386 0.0 HOH
 2.708
 O
 O
7jg3 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 THR A:165 A:971 53.0 0.379 H -79.8 -37.0 53.0 0.379 0.0 HOH
 2.764
 O
 O
7jg4 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 THR A:165 A:971 52.0 0.371 H -84.8 -38.9 52.0 0.371 0.0 HOH
 2.577
 O
 O
5j9f 1 P22102 99.51 4e-137 X-RAY
 2016-08-10 THR A:165 A:971 53.0 0.379 H -75.1 -36.7 53.0 0.379 0.0 HOH
 2.692
 O
 O
1mej 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 THR A:175 B:164 53.0 0.379 H -69.9 -35.4 53.0 0.379 0.0 HOH
 2.760
 O
 O
THR B:175 A:164 64.0 0.457 H -71.2 -35.9 NA NA NA
THR C:175 C:164 64.0 0.457 H -67.0 -37.5 NA NA NA
1men 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 THR A:175 A:164 61.0 0.436 H -60.3 -45.9 61.0 0.436 0.0 HOH
 4.041
 OG1
 O
THR B:175 B:164 53.0 0.379 H -69.7 -38.0 NA NA NA
THR C:175 C:164 67.0 0.479 H -66.1 -29.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22102-f1 1 P22102 100.0 0.0 THR A:971 A:971 61.0 0.436 H -69.8 -35.2