Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 34876556 . C A CCDS13627.1:NM_000819.4:c.2908Gca>Tca_NP_000810.1:p.970A>S Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1zlx 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 ALA A:163 A:163 68.0 0.591 H -62.8 -49.7 68.0 0.591 0.0 HOH
 4.108
 CB
 O
1zly 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 ALA A:163 A:163 69.0 0.6 H -62.5 -50.3 69.0 0.6 0.0 GRF
HOH
 9.855
3.004
 O
O
 O3
O
1meo 1 P22102 100.0 5e-138 X-RAY
 2002-12-18 ALA A:163 A:163 56.0 0.487 H -64.7 -49.0 56.0 0.487 0.0 SO4
HOH
 7.424
3.067
 O
N
 O4
O
1njs 1 P22102 100.0 5e-138 X-RAY
 2003-06-10 ALA A:163 A:163 63.0 0.548 H -58.9 -50.2 63.0 0.548 0.0 PO4
HOH
 7.484
2.950
 O
N
 O3
O
ALA B:163 B:163 69.0 0.6 H -60.9 -47.4 NA NA NA
1rbm 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ALA A:163 A:163 61.0 0.53 H -65.9 -47.2 61.0 0.53 0.0 PO4
HOH
 7.341
3.894
 O
CB
 O3
O
ALA B:163 B:163 65.0 0.565 H -59.8 -47.1 NA NA NA
1rbq 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ALA A:163 A:163 60.0 0.522 H -62.3 -50.0 60.0 0.522 0.0 PO4
HOH
 7.598
3.021
 O
N
 O2
O
ALA B:163 B:163 63.0 0.548 H -60.1 -46.8 NA NA NA
ALA C:163 C:163 68.0 0.591 H -61.4 -42.7 NA NA NA
ALA D:163 D:163 71.0 0.617 H -58.3 -45.2 NA NA NA
1rby 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ALA A:163 A:163 64.0 0.557 H -57.8 -47.7 64.0 0.557 0.0 HOH
 2.971
 N
 O
ALA B:163 B:163 63.0 0.548 H -60.8 -48.4 NA NA NA
ALA C:163 C:163 74.0 0.643 H -58.8 -48.1 NA NA NA
ALA D:163 D:163 72.0 0.626 H -59.1 -47.7 NA NA NA
1rbz 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ALA A:163 A:163 63.0 0.548 H -61.6 -48.8 63.0 0.548 0.0 KT5
HOH
 8.125
2.973
 CA
N
 OED
O
ALA B:163 B:163 72.0 0.626 H -63.9 -43.4 NA NA NA
1rc0 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ALA A:163 A:163 72.0 0.626 H -63.5 -44.0 72.0 0.626 0.0 HOH
 3.956
 O
 O
ALA B:163 B:163 64.0 0.557 H -58.6 -48.7 NA NA NA
1rc1 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ALA A:163 A:163 63.0 0.548 H -61.2 -48.6 63.0 0.548 0.0 HOH
 3.055
 N
 O
ALA B:163 B:163 71.0 0.617 H -62.2 -45.4 NA NA NA
4ew1 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 ALA A:163 A:163 55.0 0.478 H -63.3 -44.5 55.0 0.478 0.0 SO4
SO4
SO4
HOH
 7.483
8.449
6.296
3.024
 O
O
N
O
 O1
O1
O2
O
4ew2 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 ALA A:163 A:163 79.0 0.687 H -64.9 -43.1 79.0 0.687 0.0 SO4
SO4
HOH
 7.462
6.159
3.046
 O
N
N
 O1
O2
O
4ew3 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 ALA A:163 A:163 57.0 0.496 H -66.7 -44.2 57.0 0.496 0.0 SO4
SO4
HOH
 7.583
6.034
2.848
 O
N
O
 O1
O2
O
4zyt 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ALA A:164 A:970 69.0 0.6 H -58.8 -51.2 69.0 0.6 0.0 GAR
HOH
 9.780
3.820
 O
CB
 O6
O
4zyu 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ALA A:164 A:970 67.0 0.583 H -58.8 -49.8 67.0 0.583 0.0 GAR
HOH
 9.919
4.391
 O
O
 O6
O
4zyv 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ALA A:164 A:970 67.0 0.583 H -61.3 -52.8 67.0 0.583 0.0 GAR
HOH
 9.711
4.371
 O
O
 O6
O
4zyw 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ALA A:164 A:970 66.0 0.574 H -56.6 -54.2 66.0 0.574 0.0 GAR
HOH
 9.677
4.697
 O
O
 O6
O
4zyx 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ALA A:164 A:970 69.0 0.6 H -58.2 -50.3 69.0 0.6 0.0 GAR
HOH
 9.745
3.792
 O
CB
 O6
O
4zyy 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ALA A:164 A:970 68.0 0.591 H -59.2 -51.5 68.0 0.591 0.0 GAR
HOH
 9.779
3.852
 O
CB
 O6
O
4zyz 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ALA A:164 A:970 69.0 0.6 H -56.6 -51.1 69.0 0.6 0.0 GAR
HOH
 9.824
3.774
 O
CB
 O6
O
4zz0 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ALA A:164 A:970 68.0 0.591 H -57.7 -50.8 68.0 0.591 0.0 GAR
HOH
 9.821
2.911
 O
O
 O6
O
4zz1 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 ALA A:164 A:970 68.0 0.591 H -61.0 -50.3 68.0 0.591 0.0 GAR
HOH
 9.704
2.984
 O
O
 O6
O
4zz2 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 ALA A:164 A:970 68.0 0.591 H -60.9 -49.3 68.0 0.591 0.0 GAR
HOH
 9.762
2.963
 O
O
 O6
O
4zz3 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 ALA A:164 A:970 70.0 0.609 H -63.7 -50.0 70.0 0.609 0.0 HOH
 4.899
 O
 O
7jg0 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 ALA A:164 A:969 67.0 0.583 H -59.1 -55.3 67.0 0.583 0.0 GAR
HOH
 9.272
3.239
 O
O
 HO6
O
7jg3 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 ALA A:164 A:970 68.0 0.591 H -58.2 -50.9 68.0 0.591 0.0 GAR
HOH
 9.573
2.892
 O
O
 HO6
O
7jg4 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 ALA A:164 A:970 68.0 0.591 H -59.3 -47.5 68.0 0.591 0.0 GAR
HOH
 9.671
2.943
 O
O
 HO6
O
5j9f 1 P22102 99.51 4e-137 X-RAY
 2016-08-10 ALA A:164 A:970 70.0 0.609 H -58.3 -50.9 70.0 0.609 0.0 GAR
HOH
 9.806
4.877
 O
O
 O6
O
1mej 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 ALA A:174 B:163 57.0 0.496 H -68.6 -44.9 57.0 0.496 0.0 HOH
 3.009
 O
 O
ALA B:174 A:163 66.0 0.574 H -64.2 -46.4 NA NA NA
ALA C:174 C:163 65.0 0.565 H -65.2 -50.8 NA NA NA
1men 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 ALA A:174 A:163 68.0 0.591 H -58.0 -58.4 68.0 0.591 0.0 GAR
HOH
 9.731
3.950
 O
CB
 O6
O
ALA B:174 B:163 49.0 0.426 H -65.3 -46.9 NA NA NA
ALA C:174 C:163 60.0 0.522 H -67.8 -55.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22102-f1 1 P22102 100.0 0.0 ALA A:970 A:970 65.0 0.565 H -67.4 -46.4