Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 34876559 . C A CCDS13627.1:NM_000819.4:c.2905Gtc>Ttc_NP_000810.1:p.969V>F Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1zlx 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 VAL A:162 A:162 55.0 0.355 H -59.7 -38.1 55.0 0.355 0.0 HOH
 3.694
 CG1
 O
1zly 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 VAL A:162 A:162 62.0 0.4 H -54.3 -38.9 62.0 0.4 0.0 GRF
HOH
 8.955
4.287
 O
CG1
 O3
O
1meo 1 P22102 100.0 5e-138 X-RAY
 2002-12-18 VAL A:162 A:162 57.0 0.368 H -55.1 -40.5 57.0 0.368 0.0 SO4
HOH
 9.490
3.398
 O
N
 O4
O
1njs 1 P22102 100.0 5e-138 X-RAY
 2003-06-10 VAL A:162 A:162 76.0 0.49 H -55.7 -44.3 76.0 0.49 0.0 PO4
HOH
 9.543
2.960
 O
N
 O3
O
VAL B:162 B:162 75.0 0.484 H -57.7 -41.9 NA NA NA
1rbm 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 VAL A:162 A:162 55.0 0.355 H -55.1 -41.7 55.0 0.355 0.0 PO4
HOH
 9.650
3.092
 O
N
 O3
O
VAL B:162 B:162 73.0 0.471 H -57.6 -45.4 NA NA NA
1rbq 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 VAL A:162 A:162 76.0 0.49 H -54.6 -43.4 76.0 0.49 0.0 PO4
HOH
 9.646
3.007
 O
N
 O2
O
VAL B:162 B:162 74.0 0.477 H -57.2 -46.6 NA NA NA
VAL C:162 C:162 75.0 0.484 H -53.3 -46.1 NA NA NA
VAL D:162 D:162 74.0 0.477 H -55.6 -47.1 NA NA NA
1rby 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 VAL A:162 A:162 73.0 0.471 H -54.2 -45.4 73.0 0.471 0.0 GAR
HOH
 9.774
2.993
 O
N
 C1
O
VAL B:162 B:162 71.0 0.458 H -59.1 -43.7 NA NA NA
VAL C:162 C:162 56.0 0.361 H -55.3 -45.4 NA NA NA
VAL D:162 D:162 53.0 0.342 H -55.2 -45.4 NA NA NA
1rbz 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 VAL A:162 A:162 75.0 0.484 H -61.8 -40.3 75.0 0.484 0.0 KT5
HOH
 6.838
3.332
 CG1
N
 OED
O
VAL B:162 B:162 76.0 0.49 H -61.8 -40.4 NA NA NA
1rc0 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 VAL A:162 A:162 73.0 0.471 H -56.8 -42.4 73.0 0.471 0.0 HOH
 3.171
 N
 O
VAL B:162 B:162 77.0 0.497 H -57.6 -43.2 NA NA NA
1rc1 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 VAL A:162 A:162 72.0 0.465 H -54.4 -45.8 72.0 0.465 0.0 HOH
 3.647
 N
 O
VAL B:162 B:162 76.0 0.49 H -55.9 -43.9 NA NA NA
4ew1 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 VAL A:162 A:162 64.0 0.413 H -49.3 -45.0 64.0 0.413 0.0 SO4
SO4
SO4
HOH
 9.583
6.824
3.051
2.920
 O
CG1
CG1
N
 O1
O1
O2
O
4ew2 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 VAL A:162 A:162 67.0 0.432 H -48.9 -44.5 67.0 0.432 0.0 SO4
SO4
HOH
 9.565
2.943
3.052
 O
CG1
N
 O1
O2
O
4ew3 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 VAL A:162 A:162 64.0 0.413 H -50.1 -42.0 64.0 0.413 0.0 SO4
SO4
HOH
 9.681
2.797
2.933
 O
CG1
N
 O1
O2
O
4zyt 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 VAL A:163 A:969 61.0 0.394 H -54.0 -40.4 61.0 0.394 0.0 GAR
HOH
 8.730
3.676
 O
CG1
 O6
O
4zyu 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 VAL A:163 A:969 61.0 0.394 H -53.4 -42.0 61.0 0.394 0.0 GAR
HOH
 8.960
3.838
 O
CG2
 O6
O
4zyv 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 VAL A:163 A:969 62.0 0.4 H -53.5 -39.8 62.0 0.4 0.0 GAR
HOH
 8.801
3.809
 O
CG2
 O6
O
4zyw 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 VAL A:163 A:969 61.0 0.394 H -55.6 -41.6 61.0 0.394 0.0 GAR
HOH
 8.715
3.839
 O
CG2
 O6
O
4zyx 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 VAL A:163 A:969 60.0 0.387 H -53.2 -41.1 60.0 0.387 0.0 GAR
HOH
 8.756
3.814
 O
CG1
 O6
O
4zyy 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 VAL A:163 A:969 62.0 0.4 H -54.4 -40.6 62.0 0.4 0.0 GAR
HOH
 8.758
3.778
 O
CG2
 O6
O
4zyz 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 VAL A:163 A:969 61.0 0.394 H -53.4 -41.8 61.0 0.394 0.0 GAR
HOH
 8.834
3.883
 O
CG2
 O6
O
4zz0 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 VAL A:163 A:969 61.0 0.394 H -53.5 -41.1 61.0 0.394 0.0 GAR
HOH
 8.777
3.708
 O
CG1
 O6
O
4zz1 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 VAL A:163 A:969 61.0 0.394 H -54.8 -39.2 61.0 0.394 0.0 GAR
HOH
 8.644
3.576
 O
CG1
 O6
O
4zz2 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 VAL A:163 A:969 62.0 0.4 H -54.6 -39.3 62.0 0.4 0.0 GAR
HOH
 8.703
4.206
 O
CG2
 O6
O
4zz3 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 VAL A:163 A:969 59.0 0.381 H -62.9 -35.2 59.0 0.381 0.0 GAR
HOH
 9.270
4.006
 O
CG1
 O6
O
7jg0 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 VAL A:163 A:968 64.0 0.413 H -49.1 -42.3 64.0 0.413 0.0 GAR
HOH
 8.606
4.300
 CG1
CG2
 H5
O
7jg3 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 VAL A:163 A:969 63.0 0.406 H -47.0 -45.7 63.0 0.406 0.0 GAR
HOH
 8.735
5.579
 O
O
 O6
O
7jg4 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 VAL A:163 A:969 61.0 0.394 H -54.2 -41.2 61.0 0.394 0.0 GAR
HOH
 8.805
4.174
 O
CG1
 O6
O
5j9f 1 P22102 99.51 4e-137 X-RAY
 2016-08-10 VAL A:163 A:969 62.0 0.4 H -50.3 -44.4 62.0 0.4 0.0 GAR
HOH
 8.878
4.186
 O
CG1
 O6
O
1mej 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 VAL A:173 B:162 63.0 0.406 H -61.5 -34.9 63.0 0.406 0.0 HOH
 4.187
 CG1
 O
VAL B:173 A:162 62.0 0.4 H -56.9 -39.6 NA NA NA
VAL C:173 C:162 64.0 0.413 H -59.3 -37.7 NA NA NA
1men 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 VAL A:173 A:162 59.0 0.381 H -57.9 -40.6 59.0 0.381 0.0 GAR
HOH
 9.393
5.931
 O
N
 O6
O
VAL B:173 B:162 59.0 0.381 H -62.0 -37.4 NA NA NA
VAL C:173 C:162 66.0 0.426 H -59.6 -27.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22102-f1 1 P22102 100.0 0.0 VAL A:969 A:969 56.0 0.361 H -52.2 -39.3