Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 34877876 . T A CCDS13627.1:NM_000819.4:c.2717aAg>aTg_NP_000810.1:p.906K>M Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1zlx 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 LYS A:99 A:99 108.0 0.54 H -58.1 -45.0 108.0 0.54 0.0 HOH
 2.918
 O
 O
1zly 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 LYS A:99 A:99 106.0 0.53 H -62.4 -45.3 106.0 0.53 0.0 DQB
HOH
 9.941
2.831
 N
O
 NA2
O
1meo 1 P22102 100.0 5e-138 X-RAY
 2002-12-18 LYS A:99 A:99 105.0 0.525 H -58.9 -40.5 105.0 0.525 0.0 HOH
 2.832
 O
 O
1njs 1 P22102 100.0 5e-138 X-RAY
 2003-06-10 LYS A:99 A:99 101.0 0.505 H -59.6 -46.4 101.0 0.505 0.0 HOH
 2.637
 O
 O
LYS B:99 B:99 105.0 0.525 H -59.7 -40.7 NA NA NA
1rbm 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 LYS A:99 A:99 100.0 0.5 H -59.4 -43.0 100.0 0.5 0.0 HOH
 3.549
 NZ
 O
LYS B:99 B:99 103.0 0.515 H -60.7 -40.2 NA NA NA
1rbq 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 LYS A:99 A:99 102.0 0.51 H -57.3 -45.5 102.0 0.51 0.0 HOH
 2.646
 O
 O
LYS B:99 B:99 102.0 0.51 H -54.3 -45.2 NA NA NA
LYS C:99 C:99 105.0 0.525 H -62.1 -36.0 NA NA NA
LYS D:99 D:99 104.0 0.52 H -67.1 -33.1 NA NA NA
1rby 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 LYS A:99 A:99 100.0 0.5 H -64.3 -40.0 100.0 0.5 0.0 HOH
 2.883
 O
 O
LYS B:99 B:99 99.0 0.495 H -56.4 -42.6 NA NA NA
LYS C:99 C:99 101.0 0.505 H -63.1 -35.6 NA NA NA
LYS D:99 D:99 99.0 0.495 H -64.9 -38.3 NA NA NA
1rbz 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 LYS A:99 A:99 96.0 0.48 H -58.7 -43.0 96.0 0.48 0.0 HOH
 5.835
 C
 O
LYS B:99 B:99 107.0 0.535 H -57.3 -43.1 NA NA NA
1rc0 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 LYS A:99 A:99 105.0 0.525 H -58.4 -42.7 105.0 0.525 0.0 HOH
 5.971
 C
 O
LYS B:99 B:99 105.0 0.525 H -53.0 -46.3 NA NA NA
1rc1 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 LYS A:99 A:99 106.0 0.53 H -57.3 -44.3 106.0 0.53 0.0 HOH
 5.881
 C
 O
LYS B:99 B:99 110.0 0.55 H -65.2 -38.1 NA NA NA
4ew1 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 LYS A:99 A:99 109.0 0.545 H -58.5 -41.5 109.0 0.545 0.0 HOH
 2.813
 O
 O
4ew2 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 LYS A:99 A:99 113.0 0.565 H -57.8 -40.1 113.0 0.565 0.0 HOH
 2.798
 O
 O
4ew3 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 LYS A:99 A:99 112.0 0.56 H -57.7 -41.1 112.0 0.56 0.0 HOH
 2.855
 O
 O
4zyt 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 LYS A:100 A:906 100.0 0.5 H -60.3 -38.3 100.0 0.5 0.0 HOH
 2.920
 O
 O
4zyu 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 LYS A:100 A:906 105.0 0.525 H -58.1 -42.5 105.0 0.525 0.0 HOH
 2.513
 O
 O
4zyv 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 LYS A:100 A:906 106.0 0.53 H -56.5 -42.8 106.0 0.53 0.0 HOH
 2.661
 O
 O
4zyw 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 LYS A:100 A:906 99.0 0.495 H -60.8 -40.7 99.0 0.495 0.0 HOH
 2.611
 O
 O
4zyx 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 LYS A:100 A:906 102.0 0.51 H -62.3 -39.6 102.0 0.51 0.0 HOH
 2.790
 O
 O
4zyy 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 LYS A:100 A:906 107.0 0.535 H -60.5 -39.2 107.0 0.535 0.0 HOH
 2.781
 O
 O
4zyz 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 LYS A:100 A:906 111.0 0.555 H -60.1 -39.7 111.0 0.555 0.0 HOH
 2.795
 O
 O
4zz0 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 LYS A:100 A:906 100.0 0.5 H -60.9 -38.4 100.0 0.5 0.0 HOH
 2.775
 O
 O
4zz1 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 LYS A:100 A:906 112.0 0.56 H -58.4 -39.4 112.0 0.56 0.0 HOH
 2.776
 O
 O
4zz2 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 LYS A:100 A:906 102.0 0.51 H -58.1 -40.2 102.0 0.51 0.0 HOH
 2.778
 O
 O
4zz3 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 LYS A:100 A:906 100.0 0.5 H -65.4 -44.7 100.0 0.5 0.0 HOH
 2.572
 O
 O
7jg0 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 LYS A:100 A:905 105.0 0.525 H -56.8 -42.8 105.0 0.525 0.0 HOH
 2.830
 O
 O
7jg3 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 LYS A:100 A:906 107.0 0.535 H -54.7 -36.8 107.0 0.535 0.0 NA
HOH
 6.219
3.131
 C
O
 NA
O
7jg4 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 LYS A:100 A:906 100.0 0.5 H -59.2 -45.3 100.0 0.5 0.0 HOH
 3.154
 O
 O
5j9f 1 P22102 99.51 4e-137 X-RAY
 2016-08-10 LYS A:100 A:906 105.0 0.525 H -60.1 -39.8 105.0 0.525 0.0 HOH
 2.689
 O
 O
1mej 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 LYS A:110 B:99 91.0 0.455 H -57.6 -40.2 91.0 0.455 0.0 HOH
 2.995
 O
 O
LYS B:110 A:99 108.0 0.54 H -58.1 -39.6 NA NA NA
LYS C:110 C:99 87.0 0.435 H -57.4 -37.9 NA NA NA
1men 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 LYS A:110 A:99 90.0 0.45 H -56.8 -44.9 90.0 0.45 0.0 HOH
 5.708
 C
 O
LYS B:110 B:99 90.0 0.45 H -51.5 -37.2 NA NA NA
LYS C:110 C:99 82.0 0.41 H -57.1 -40.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22102-f1 1 P22102 100.0 0.0 LYS A:906 A:906 98.0 0.49 H -61.8 -39.2