Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 34877958 . C A CCDS13627.1:NM_000819.4:c.2635Gac>Tac_NP_000810.1:p.879D>Y Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
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auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1zlx 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 ASP A:72 A:72 31.0 0.207 H -52.8 -30.2 31.0 0.207 0.0 HOH
 4.520
 CB
 O
1zly 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 ASP A:72 A:72 30.0 0.2 H -54.5 -26.0 30.0 0.2 0.0 HOH
 3.051
 C
 O
1meo 1 P22102 100.0 5e-138 X-RAY
 2002-12-18 ASP A:72 A:72 20.0 0.133 H -56.1 -40.2 20.0 0.133 0.0 HOH
 5.654
 O
 O
1njs 1 P22102 100.0 5e-138 X-RAY
 2003-06-10 ASP A:72 A:72 35.0 0.233 H -57.3 -36.7 35.0 0.233 0.0 HOH
 4.046
 CB
 O
ASP B:72 B:72 30.0 0.2 H -60.9 -37.0 NA NA NA
1rbm 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ASP A:72 A:72 31.0 0.207 H -56.3 -38.8 31.0 0.207 0.0 HOH
 4.944
 OD2
 O
ASP B:72 B:72 24.0 0.16 H -59.1 -38.2 NA NA NA
1rbq 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ASP A:72 A:72 32.0 0.213 H -55.4 -38.1 32.0 0.213 0.0 HOH
 6.202
 N
 O
ASP B:72 B:72 32.0 0.213 H -55.4 -41.4 NA NA NA
ASP C:72 C:72 31.0 0.207 H -61.9 -32.5 NA NA NA
ASP D:72 D:72 31.0 0.207 H -63.1 -36.6 NA NA NA
1rby 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ASP A:72 A:72 32.0 0.213 H -56.3 -40.1 32.0 0.213 0.0 HOH
 6.122
 N
 O
ASP B:72 B:72 31.0 0.207 H -55.4 -40.1 NA NA NA
ASP C:72 C:72 30.0 0.2 H -58.1 -33.8 NA NA NA
ASP D:72 D:72 31.0 0.207 H -60.3 -38.0 NA NA NA
1rbz 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ASP A:72 A:72 33.0 0.22 H -56.1 -34.2 33.0 0.22 0.0 HOH
 6.346
 N
 O
ASP B:72 B:72 30.0 0.2 H -62.3 -27.6 NA NA NA
1rc0 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ASP A:72 A:72 28.0 0.187 H -66.7 -29.8 28.0 0.187 0.0
ASP B:72 B:72 26.0 0.173 H -64.3 -30.9 NA NA NA
1rc1 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ASP A:72 A:72 30.0 0.2 H -59.8 -32.9 30.0 0.2 0.0 HOH
 6.112
 N
 O
ASP B:72 B:72 27.0 0.18 H -65.0 -31.1 NA NA NA
4ew1 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 ASP A:72 A:72 20.0 0.133 H -59.2 -37.9 20.0 0.133 0.0 HOH
 2.441
 OD2
 O
4ew2 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 ASP A:72 A:72 19.0 0.127 H -58.3 -37.8 19.0 0.127 0.0 HOH
 5.824
 OD1
 O
4ew3 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 ASP A:72 A:72 19.0 0.127 H -57.0 -37.8 19.0 0.127 0.0 HOH
 6.120
 C
 O
4zyt 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ASP A:73 A:879 26.0 0.173 H -58.0 -37.1 26.0 0.173 0.0 HOH
 6.031
 OD1
 O
4zyu 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ASP A:73 A:879 29.0 0.193 H -57.5 -36.9 29.0 0.193 0.0 HOH
 7.102
 O
 O
4zyv 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ASP A:73 A:879 32.0 0.213 H -55.2 -37.8 32.0 0.213 0.0 HOH
 8.011
 OD1
 O
4zyw 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ASP A:73 A:879 30.0 0.2 H -54.8 -41.1 30.0 0.2 0.0 HOH
 6.117
 N
 O
4zyx 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ASP A:73 A:879 27.0 0.18 H -58.9 -37.4 27.0 0.18 0.0 HOH
 3.020
 OD2
 O
4zyy 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ASP A:73 A:879 27.0 0.18 H -57.8 -36.3 27.0 0.18 0.0 HOH
 6.068
 N
 O
4zyz 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ASP A:73 A:879 29.0 0.193 H -58.9 -36.0 29.0 0.193 0.0 HOH
 3.105
 OD2
 O
4zz0 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ASP A:73 A:879 30.0 0.2 H -58.1 -37.1 30.0 0.2 0.0 HOH
 2.979
 OD2
 O
4zz1 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 ASP A:73 A:879 28.0 0.187 H -58.2 -37.1 28.0 0.187 0.0 HOH
 3.024
 OD2
 O
4zz2 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 ASP A:73 A:879 27.0 0.18 H -59.9 -34.5 27.0 0.18 0.0 HOH
 2.562
 OD2
 O
4zz3 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 ASP A:73 A:879 33.0 0.22 H -57.7 -35.3 33.0 0.22 0.0 HOH
 9.520
 OD1
 O
7jg0 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 ASP A:73 A:878 26.0 0.173 H -58.7 -37.9 26.0 0.173 0.0 HOH
 2.651
 OD2
 O
7jg3 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 ASP A:73 A:879 29.0 0.193 H -56.1 -38.3 29.0 0.193 0.0 HOH
 2.624
 OD2
 O
7jg4 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 ASP A:73 A:879 30.0 0.2 H -39.0 -51.8 30.0 0.2 0.0 HOH
 2.933
 OD2
 O
5j9f 1 P22102 99.51 4e-137 X-RAY
 2016-08-10 ASP A:73 A:879 30.0 0.2 H -57.9 -34.5 30.0 0.2 0.0 HOH
 6.109
 N
 O
1mej 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 ASP A:83 B:72 33.0 0.22 H -61.5 -34.2 33.0 0.22 0.0 HOH
 2.671
 OD2
 O
ASP B:83 A:72 34.0 0.227 H -63.1 -28.2 NA NA NA
ASP C:83 C:72 33.0 0.22 H -63.0 -31.6 NA NA NA
1men 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 ASP A:83 A:72 28.0 0.187 H -60.1 -29.1 28.0 0.187 0.0 HOH
 3.906
 CB
 O
ASP B:83 B:72 29.0 0.193 H -63.7 -31.5 NA NA NA
ASP C:83 C:72 30.0 0.2 H -56.4 -32.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22102-f1 1 P22102 100.0 0.0 ASP A:879 A:879 23.0 0.153 H -56.8 -42.7