Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 34877984 . T A CCDS13627.1:NM_000819.4:c.2609aAt>aTt_NP_000810.1:p.870N>I Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1zlx 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 ASN A:63 A:63 106.0 0.662 -72.2 -164.3 106.0 0.662 0.0 HOH
 3.541
 ND2
 O
1zly 1 P22102 100.0 3e-138 X-RAY
 2005-08-23 ASN A:63 A:63 109.0 0.681 -76.1 -164.0 109.0 0.681 0.0 HOH
 2.679
 OD1
 O
1meo 1 P22102 100.0 5e-138 X-RAY
 2002-12-18 ASN A:63 A:63 74.0 0.463 S -152.0 -173.2 74.0 0.463 0.0 HOH
 3.523
 CB
 O
1njs 1 P22102 100.0 5e-138 X-RAY
 2003-06-10 ASN A:63 A:63 79.0 0.494 S -149.0 174.8 79.0 0.494 0.0 HOH
 3.289
 CB
 O
ASN B:63 B:63 66.0 0.412 S -146.4 177.2 NA NA NA
1rbm 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ASN A:63 A:63 77.0 0.481 S -152.5 175.2 77.0 0.481 0.0 KT5
HOH
 9.888
3.605
 C
CB
 O1A
O
ASN B:63 B:63 81.0 0.506 S -147.3 168.6 NA NA NA
1rbq 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ASN A:63 A:63 79.0 0.494 S -152.1 175.0 79.0 0.494 0.0 HOH
 3.753
 CB
 O
ASN B:63 B:63 75.0 0.469 S -151.7 173.8 NA NA NA
ASN C:63 C:63 67.0 0.419 S -149.0 176.8 NA NA NA
ASN D:63 D:63 79.0 0.494 S -154.0 179.6 NA NA NA
1rby 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ASN A:63 A:63 84.0 0.525 S -149.8 176.9 84.0 0.525 0.0 HOH
 3.156
 CB
 O
ASN B:63 B:63 81.0 0.506 S -143.6 -177.2 NA NA NA
ASN C:63 C:63 83.0 0.519 S -151.3 -178.4 NA NA NA
ASN D:63 D:63 67.0 0.419 S -148.5 178.6 NA NA NA
1rbz 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ASN A:63 A:63 71.0 0.444 S -146.1 -173.7 71.0 0.444 0.0 HOH
 3.430
 O
 O
ASN B:63 B:63 72.0 0.45 S -148.4 -178.5 NA NA NA
1rc0 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ASN A:63 A:63 70.0 0.438 S -148.9 176.9 70.0 0.438 0.0 KT5
HOH
 9.957
5.454
 C
O
 O1A
O
ASN B:63 B:63 72.0 0.45 S -154.9 171.9 NA NA NA
1rc1 1 P22102 100.0 5e-138 X-RAY
 2005-06-14 ASN A:63 A:63 77.0 0.481 S -149.9 -178.9 77.0 0.481 0.0 KT3
HOH
 9.952
5.378
 C
O
 O1A
O
ASN B:63 B:63 75.0 0.469 S -154.5 177.6 NA NA NA
4ew1 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 ASN A:63 A:63 76.0 0.475 S -161.6 176.6 76.0 0.475 0.0 HOH
 2.801
 ND2
 O
4ew2 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 ASN A:63 A:63 74.0 0.463 S -160.6 177.9 74.0 0.463 0.0 DXY
HOH
 9.841
2.889
 C
ND2
 O
O
4ew3 1 P22102 100.0 5e-138 X-RAY
 2013-07-31 ASN A:63 A:63 77.0 0.481 S -157.9 179.4 77.0 0.481 0.0 DXZ
HOH
 9.907
2.809
 C
ND2
 O
O
4zyt 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ASN A:64 A:870 84.0 0.525 S -152.4 178.1 84.0 0.525 0.0 3Y9
HOH
 8.815
3.543
 C
CB
 O28
O
4zyu 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ASN A:64 A:870 85.0 0.531 S -152.4 -175.9 85.0 0.531 0.0
4zyv 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ASN A:64 A:870 81.0 0.506 S -127.3 -177.9 81.0 0.506 0.0 G71
HOH
 9.241
4.735
 C
N
 O27
O
4zyw 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ASN A:64 A:870 76.0 0.475 S -146.5 -172.7 76.0 0.475 0.0 G94
 9.451
 C
 O24
4zyx 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ASN A:64 A:870 84.0 0.525 S -157.5 -179.4 84.0 0.525 0.0 3YB
HOH
 9.622
3.245
 C
ND2
 O27
O
4zyy 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ASN A:64 A:870 80.0 0.5 S -148.1 178.7 80.0 0.5 0.0 3YC
HOH
 9.798
4.496
 C
N
 O27
O
4zyz 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ASN A:64 A:870 84.0 0.525 S -152.4 -177.3 84.0 0.525 0.0 3YD
HOH
 9.604
3.334
 C
ND2
 O28
O
4zz0 1 P22102 100.0 5e-138 X-RAY
 2016-04-20 ASN A:64 A:870 83.0 0.519 S -145.6 179.7 83.0 0.519 0.0 3YE
HOH
 9.606
3.158
 C
ND2
 O27
O
4zz1 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 ASN A:64 A:870 83.0 0.519 S -158.9 178.7 83.0 0.519 0.0 3YF
HOH
 9.724
2.870
 C
ND2
 O27
O
4zz2 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 ASN A:64 A:870 84.0 0.525 S -156.6 178.4 84.0 0.525 0.0 3YG
HOH
 9.638
2.900
 C
ND2
 O27
O
4zz3 1 P22102 100.0 5e-138 X-RAY
 2015-12-16 ASN A:64 A:870 94.0 0.588 S -159.5 -157.1 94.0 0.588 0.0
7jg0 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 ASN A:64 A:869 81.0 0.506 S -150.8 -179.3 81.0 0.506 0.0 V97
HOH
 9.194
3.139
 C
CB
 O28
O
7jg3 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 ASN A:64 A:870 77.0 0.481 S -140.9 -179.7 77.0 0.481 0.0 V9A
HOH
 9.770
3.121
 C
O
 O27
O
7jg4 1 P22102 100.0 5e-138 X-RAY
 2021-03-31 ASN A:64 A:870 70.0 0.438 S -120.8 177.4 70.0 0.438 0.0 HOH
 2.809
 O
 O
5j9f 1 P22102 99.51 4e-137 X-RAY
 2016-08-10 ASN A:64 A:870 70.0 0.438 S -140.3 179.6 70.0 0.438 0.0
1mej 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 ASN A:74 B:63 88.0 0.55 S -168.5 176.8 88.0 0.55 0.0 HOH
 3.688
 O
 O
ASN B:74 A:63 86.0 0.537 S -150.7 -177.3 NA NA NA
ASN C:74 C:63 85.0 0.531 S -155.3 177.6 NA NA NA
1men 1 P22102 100.0 3e-136 X-RAY
 2002-12-18 ASN A:74 A:63 84.0 0.525 S -153.9 179.6 84.0 0.525 0.0
ASN B:74 B:63 84.0 0.525 S -172.5 177.5 NA NA NA
ASN C:74 C:63 66.0 0.412 S -151.2 -175.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22102-f1 1 P22102 100.0 0.0 ASN A:870 A:870 77.0 0.481 S -147.5 171.2