Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr21 | 34878346 | . | C | A | CCDS13627.1:NM_000819.4:c.2518Gtt>Ttt_NP_000810.1:p.840V>F | Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1zlx | 1 | P22102 | 100.0 | 3e-138 |
X-RAY |
2005-08-23 | VAL | A:33 | A:33 | 0.0 | 0.0 | E | -117.5 | 113.0 | 0.0 | 0.0 | 0.0 |
GOL HOH |
8.312 7.435 |
CG2 N |
C1 O |
||
| 1zly | 1 | P22102 | 100.0 | 3e-138 |
X-RAY |
2005-08-23 | VAL | A:33 | A:33 | 0.0 | 0.0 | E | -119.7 | 118.7 | 0.0 | 0.0 | 0.0 |
HOH |
7.212 |
O |
O |
||
| 1meo | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2002-12-18 | VAL | A:33 | A:33 | 0.0 | 0.0 | E | -123.0 | 125.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.755 |
O |
O |
||
| 1njs | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2003-06-10 | VAL | A:33 | A:33 | 0.0 | 0.0 | E | -124.1 | 127.7 | 0.0 | 0.0 | 0.0 |
PO4 HOH |
9.969 7.037 |
CG1 O |
O3 O |
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| VAL | B:33 | B:33 | 0.0 | 0.0 | E | -119.5 | 126.2 | NA | NA | NA | |||||||||||||
| 1rbm | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | VAL | A:33 | A:33 | 0.0 | 0.0 | E | -125.9 | 125.8 | 0.0 | 0.0 | 0.0 |
PO4 HOH |
9.946 7.074 |
CG1 O |
O2 O |
||
| VAL | B:33 | B:33 | 0.0 | 0.0 | E | -120.1 | 127.7 | NA | NA | NA | |||||||||||||
| 1rbq | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | VAL | A:33 | A:33 | 0.0 | 0.0 | E | -122.2 | 127.5 | 0.0 | 0.0 | 0.0 |
PO4 HOH |
9.928 7.121 |
CG1 O |
O2 O |
||
| VAL | B:33 | B:33 | 0.0 | 0.0 | E | -122.6 | 126.6 | NA | NA | NA | |||||||||||||
| VAL | C:33 | C:33 | 0.0 | 0.0 | E | -122.3 | 125.8 | NA | NA | NA | |||||||||||||
| VAL | D:33 | D:33 | 0.0 | 0.0 | E | -118.7 | 127.7 | NA | NA | NA | |||||||||||||
| 1rby | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | VAL | A:33 | A:33 | 0.0 | 0.0 | E | -123.5 | 122.9 | 0.0 | 0.0 | 0.0 |
GAR HOH |
9.760 7.051 |
CG1 O |
O18 O |
||
| VAL | B:33 | B:33 | 0.0 | 0.0 | E | -124.1 | 126.0 | NA | NA | NA | |||||||||||||
| VAL | C:33 | C:33 | 0.0 | 0.0 | E | -121.5 | 124.6 | NA | NA | NA | |||||||||||||
| VAL | D:33 | D:33 | 0.0 | 0.0 | E | -118.7 | 126.2 | NA | NA | NA | |||||||||||||
| 1rbz | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | VAL | A:33 | A:33 | 0.0 | 0.0 | E | -123.6 | 120.7 | 0.0 | 0.0 | 0.0 |
HOH |
7.111 |
O |
O |
||
| VAL | B:33 | B:33 | 0.0 | 0.0 | E | -121.0 | 124.2 | NA | NA | NA | |||||||||||||
| 1rc0 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | VAL | A:33 | A:33 | 0.0 | 0.0 | E | -121.4 | 126.5 | 0.0 | 0.0 | 0.0 |
HOH |
7.691 |
O |
O |
||
| VAL | B:33 | B:33 | 0.0 | 0.0 | E | -119.3 | 126.4 | NA | NA | NA | |||||||||||||
| 1rc1 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | VAL | A:33 | A:33 | 0.0 | 0.0 | E | -129.7 | 124.6 | 0.0 | 0.0 | 0.0 |
PO4 HOH |
9.989 7.420 |
CG1 N |
O2 O |
||
| VAL | B:33 | B:33 | 0.0 | 0.0 | E | -122.3 | 122.9 | NA | NA | NA | |||||||||||||
| 4ew1 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2013-07-31 | VAL | A:33 | A:33 | 0.0 | 0.0 | E | -122.2 | 124.7 | 0.0 | 0.0 | 0.0 |
HOH |
6.623 |
O |
O |
||
| 4ew2 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2013-07-31 | VAL | A:33 | A:33 | 0.0 | 0.0 | E | -124.1 | 124.6 | 0.0 | 0.0 | 0.0 |
HOH |
6.833 |
O |
O |
||
| 4ew3 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2013-07-31 | VAL | A:33 | A:33 | 0.0 | 0.0 | E | -121.7 | 124.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.640 |
O |
O |
||
| 4zyt | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | VAL | A:34 | A:840 | 0.0 | 0.0 | E | -117.5 | 128.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.934 |
O |
O |
||
| 4zyu | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | VAL | A:34 | A:840 | 0.0 | 0.0 | E | -115.9 | 125.2 | 0.0 | 0.0 | 0.0 |
HOH |
7.424 |
N |
O |
||
| 4zyv | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | VAL | A:34 | A:840 | 0.0 | 0.0 | E | -120.0 | 130.7 | 0.0 | 0.0 | 0.0 |
HOH |
7.015 |
O |
O |
||
| 4zyw | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | VAL | A:34 | A:840 | 0.0 | 0.0 | E | -115.8 | 127.9 | 0.0 | 0.0 | 0.0 |
HOH |
7.343 |
N |
O |
||
| 4zyx | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | VAL | A:34 | A:840 | 0.0 | 0.0 | E | -116.4 | 126.2 | 0.0 | 0.0 | 0.0 |
HOH |
7.044 |
O |
O |
||
| 4zyy | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | VAL | A:34 | A:840 | 0.0 | 0.0 | E | -117.3 | 126.6 | 0.0 | 0.0 | 0.0 |
HOH |
6.909 |
O |
O |
||
| 4zyz | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | VAL | A:34 | A:840 | 0.0 | 0.0 | E | -116.3 | 126.2 | 0.0 | 0.0 | 0.0 |
HOH |
6.983 |
O |
O |
||
| 4zz0 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | VAL | A:34 | A:840 | 0.0 | 0.0 | E | -116.9 | 127.8 | 0.0 | 0.0 | 0.0 |
HOH |
7.088 |
O |
O |
||
| 4zz1 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2015-12-16 | VAL | A:34 | A:840 | 0.0 | 0.0 | E | -118.8 | 127.5 | 0.0 | 0.0 | 0.0 |
HOH |
7.018 |
O |
O |
||
| 4zz2 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2015-12-16 | VAL | A:34 | A:840 | 0.0 | 0.0 | E | -118.2 | 127.6 | 0.0 | 0.0 | 0.0 |
HOH |
7.084 |
O |
O |
||
| 4zz3 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2015-12-16 | VAL | A:34 | A:840 | 0.0 | 0.0 | E | -118.0 | 126.1 | 0.0 | 0.0 | 0.0 |
HOH |
7.534 |
N |
O |
||
| 7jg0 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2021-03-31 | VAL | A:34 | A:839 | 0.0 | 0.0 | E | -117.5 | 126.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.956 |
O |
O |
||
| 7jg3 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2021-03-31 | VAL | A:34 | A:840 | 0.0 | 0.0 | E | -118.3 | 129.2 | 0.0 | 0.0 | 0.0 |
HOH |
6.500 |
O |
O |
||
| 7jg4 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2021-03-31 | VAL | A:34 | A:840 | 0.0 | 0.0 | E | -121.2 | 124.6 | 0.0 | 0.0 | 0.0 |
HOH |
8.680 |
CG1 |
O |
||
| 5j9f | 1 | P22102 | 99.51 | 4e-137 |
X-RAY |
2016-08-10 | VAL | A:34 | A:840 | 0.0 | 0.0 | E | -117.4 | 128.3 | 0.0 | 0.0 | 0.0 |
HOH |
7.973 |
CG1 |
O |
||
| 1mej | 1 | P22102 | 100.0 | 3e-136 |
X-RAY |
2002-12-18 | VAL | A:44 | B:33 | 0.0 | 0.0 | E | -126.8 | 129.9 | 0.0 | 0.0 | 0.0 |
HOH |
7.166 |
O |
O |
||
| VAL | B:44 | A:33 | 0.0 | 0.0 | E | -125.0 | 127.2 | NA | NA | NA | |||||||||||||
| VAL | C:44 | C:33 | 0.0 | 0.0 | E | -127.4 | 128.3 | NA | NA | NA | |||||||||||||
| 1men | 1 | P22102 | 100.0 | 3e-136 |
X-RAY |
2002-12-18 | VAL | A:44 | A:33 | 0.0 | 0.0 | E | -129.1 | 129.7 | 0.0 | 0.0 | 0.0 |
HOH |
6.944 |
O |
O |
||
| VAL | B:44 | B:33 | 0.0 | 0.0 | E | -124.7 | 127.5 | NA | NA | NA | |||||||||||||
| VAL | C:44 | C:33 | 0.0 | 0.0 | E | -121.9 | 118.5 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p22102-f1 | 1 | P22102 | 100.0 | 0.0 | VAL | A:840 | A:840 | 0.0 | 0.0 | E | -112.5 | 123.2 | |