Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr21 | 34878373 | . | G | A | CCDS13627.1:NM_000819.4:c.2491Cca>Tca_NP_000810.1:p.831P>S | Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1zlx | 1 | P22102 | 100.0 | 3e-138 |
X-RAY |
2005-08-23 | PRO | A:24 | A:24 | 122.0 | 0.841 | T | -52.6 | -35.9 | 122.0 | 0.841 | 0.0 |
GOL HOH |
8.883 3.236 |
N CD |
C3 O |
||
| 1zly | 1 | P22102 | 100.0 | 3e-138 |
X-RAY |
2005-08-23 | PRO | A:24 | A:24 | 122.0 | 0.841 | T | -50.5 | -39.5 | 122.0 | 0.841 | 0.0 |
HOH |
3.509 |
CD |
O |
||
| 1meo | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2002-12-18 | PRO | A:24 | A:24 | 114.0 | 0.786 | T | -47.8 | -61.1 | 114.0 | 0.786 | 0.0 |
HOH |
3.741 |
O |
O |
||
| 1njs | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2003-06-10 | PRO | A:24 | A:24 | 101.0 | 0.697 | T | -68.9 | 148.3 | 101.0 | 0.697 | 0.0 |
HOH |
5.179 |
O |
O |
||
| PRO | B:24 | B:24 | 130.0 | 0.897 | T | -52.4 | -45.2 | NA | NA | NA | |||||||||||||
| 1rbm | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | PRO | A:24 | A:24 | 99.0 | 0.683 | T | -70.5 | 146.8 | 99.0 | 0.683 | 0.0 |
HOH |
7.195 |
CD |
O |
||
| PRO | B:24 | B:24 | 139.0 | 0.959 | T | -62.9 | -35.8 | NA | NA | NA | |||||||||||||
| 1rbq | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | PRO | A:24 | A:24 | 100.0 | 0.69 | T | -71.2 | 153.4 | 100.0 | 0.69 | 0.0 |
HOH |
5.977 |
N |
O |
||
| PRO | B:24 | B:24 | 99.0 | 0.683 | T | -69.5 | 146.4 | NA | NA | NA | |||||||||||||
| PRO | C:24 | C:24 | 101.0 | 0.697 | T | -59.5 | 147.8 | NA | NA | NA | |||||||||||||
| PRO | D:24 | D:24 | 120.0 | 0.828 | T | -67.8 | 149.4 | NA | NA | NA | |||||||||||||
| 1rby | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | PRO | A:24 | A:24 | 99.0 | 0.683 | T | -64.8 | 150.4 | 99.0 | 0.683 | 0.0 |
HOH |
7.047 |
C |
O |
||
| PRO | B:24 | B:24 | 100.0 | 0.69 | T | -66.7 | 148.4 | NA | NA | NA | |||||||||||||
| PRO | C:24 | C:24 | 105.0 | 0.724 | T | -62.2 | 148.7 | NA | NA | NA | |||||||||||||
| PRO | D:24 | D:24 | 104.0 | 0.717 | T | -65.2 | 150.5 | NA | NA | NA | |||||||||||||
| 1rbz | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | PRO | A:24 | A:24 | 102.0 | 0.703 | T | -61.9 | 140.2 | 102.0 | 0.703 | 0.0 |
HOH |
7.132 |
O |
O |
||
| PRO | B:24 | B:24 | 109.0 | 0.752 | T | -59.2 | 141.4 | NA | NA | NA | |||||||||||||
| 1rc0 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | PRO | A:24 | A:24 | 125.0 | 0.862 | T | -57.4 | -43.6 | 125.0 | 0.862 | 0.0 | ||||||
| PRO | B:24 | B:24 | 104.0 | 0.717 | T | -65.5 | 145.7 | NA | NA | NA | |||||||||||||
| 1rc1 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2005-06-14 | PRO | A:24 | A:24 | 115.0 | 0.793 | T | -58.0 | -44.2 | 115.0 | 0.793 | 0.0 |
HOH |
8.197 |
C |
O |
||
| PRO | B:24 | B:24 | 129.0 | 0.89 | T | -65.1 | -37.8 | NA | NA | NA | |||||||||||||
| 4ew1 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2013-07-31 | PRO | A:24 | A:24 | 117.0 | 0.807 | T | -50.5 | -44.8 | 117.0 | 0.807 | 0.0 |
HOH |
3.188 |
N |
O |
||
| 4ew2 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2013-07-31 | PRO | A:24 | A:24 | 113.0 | 0.779 | T | -40.7 | -56.7 | 113.0 | 0.779 | 0.0 |
HOH |
3.167 |
CG |
O |
||
| 4ew3 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2013-07-31 | PRO | A:24 | A:24 | 110.0 | 0.759 | T | -38.6 | -54.2 | 110.0 | 0.759 | 0.0 |
HOH |
3.140 |
CB |
O |
||
| 4zyt | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | PRO | A:25 | A:831 | 122.0 | 0.841 | T | -52.7 | -38.9 | 122.0 | 0.841 | 0.0 |
HOH |
3.325 |
N |
O |
||
| 4zyu | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | PRO | A:25 | A:831 | 121.0 | 0.834 | T | -54.8 | -38.8 | 121.0 | 0.834 | 0.0 |
HOH |
3.419 |
CD |
O |
||
| 4zyv | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | PRO | A:25 | A:831 | 119.0 | 0.821 | T | -49.8 | -39.2 | 119.0 | 0.821 | 0.0 |
HOH |
3.361 |
CD |
O |
||
| 4zyw | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | PRO | A:25 | A:831 | 127.0 | 0.876 | T | -52.3 | -37.5 | 127.0 | 0.876 | 0.0 |
HOH |
3.358 |
CD |
O |
||
| 4zyx | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | PRO | A:25 | A:831 | 119.0 | 0.821 | T | -49.4 | -40.3 | 119.0 | 0.821 | 0.0 |
HOH |
3.297 |
N |
O |
||
| 4zyy | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | PRO | A:25 | A:831 | 122.0 | 0.841 | T | -53.3 | -40.4 | 122.0 | 0.841 | 0.0 |
HOH |
3.392 |
N |
O |
||
| 4zyz | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | PRO | A:25 | A:831 | 120.0 | 0.828 | T | -50.6 | -39.9 | 120.0 | 0.828 | 0.0 |
HOH |
3.369 |
N |
O |
||
| 4zz0 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2016-04-20 | PRO | A:25 | A:831 | 120.0 | 0.828 | T | -52.1 | -38.9 | 120.0 | 0.828 | 0.0 |
HOH |
3.340 |
CD |
O |
||
| 4zz1 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2015-12-16 | PRO | A:25 | A:831 | 131.0 | 0.903 | T | -51.3 | -39.3 | 131.0 | 0.903 | 0.0 |
HOH |
3.403 |
CD |
O |
||
| 4zz2 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2015-12-16 | PRO | A:25 | A:831 | 121.0 | 0.834 | T | -51.6 | -38.7 | 121.0 | 0.834 | 0.0 |
HOH |
3.372 |
CD |
O |
||
| 4zz3 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2015-12-16 | PRO | A:25 | A:831 | 123.0 | 0.848 | T | -55.3 | -32.8 | 123.0 | 0.848 | 0.0 |
HOH |
3.293 |
CD |
O |
||
| 7jg0 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2021-03-31 | PRO | A:25 | A:830 | 128.0 | 0.883 | T | -52.0 | -37.2 | 128.0 | 0.883 | 0.0 |
HOH |
3.376 |
N |
O |
||
| 7jg3 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2021-03-31 | PRO | A:25 | A:831 | 128.0 | 0.883 | T | -51.6 | -38.7 | 128.0 | 0.883 | 0.0 |
HOH |
3.515 |
CD |
O |
||
| 7jg4 | 1 | P22102 | 100.0 | 5e-138 |
X-RAY |
2021-03-31 | PRO | A:25 | A:831 | 120.0 | 0.828 | T | -49.4 | -46.5 | 120.0 | 0.828 | 0.0 |
HOH |
3.277 |
CD |
O |
||
| 5j9f | 1 | P22102 | 99.51 | 4e-137 |
X-RAY |
2016-08-10 | PRO | A:25 | A:831 | 122.0 | 0.841 | T | -53.3 | -40.2 | 122.0 | 0.841 | 0.0 |
HOH |
3.461 |
N |
O |
||
| 1mej | 1 | P22102 | 100.0 | 3e-136 |
X-RAY |
2002-12-18 | PRO | A:35 | B:24 | 133.0 | 0.917 | T | -50.5 | -37.0 | 133.0 | 0.917 | 0.0 |
HOH |
6.544 |
N |
O |
||
| PRO | B:35 | A:24 | 103.0 | 0.71 | T | -53.9 | -46.6 | NA | NA | NA | |||||||||||||
| PRO | C:35 | C:24 | 120.0 | 0.828 | T | -50.0 | -57.0 | NA | NA | NA | |||||||||||||
| 1men | 1 | P22102 | 100.0 | 3e-136 |
X-RAY |
2002-12-18 | PRO | A:35 | A:24 | 99.0 | 0.683 | T | -45.3 | -52.1 | 99.0 | 0.683 | 0.0 | ||||||
| PRO | B:35 | B:24 | 126.0 | 0.869 | T | -43.5 | -30.8 | NA | NA | NA | |||||||||||||
| PRO | C:35 | C:24 | 103.0 | 0.71 | T | -84.9 | 146.3 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p22102-f1 | 1 | P22102 | 100.0 | 0.0 | PRO | A:831 | A:831 | 31.0 | 0.214 | T | -98.9 | -34.7 | |