Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 42540494 . C A CCDS13668.1:NM_012105.4:c.304Ccg>Acg_NP_036237.2:p.102P>T Homo sapiens beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6uj0 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 PRO A:102 A:40 79.0 0.545 T -57.7 139.5 79.0 0.545 0.0 HOH
 2.812
 O
 O
PRO B:102 B:40 73.0 0.503 T -59.9 135.7 NA NA NA
6uj1 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 PRO A:102 A:40 82.0 0.566 T -75.0 130.9 82.0 0.566 0.0
PRO B:102 B:40 88.0 0.607 T -58.0 135.6 NA NA NA
3zkm 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:28 A:40 82.0 0.566 T -65.3 132.9 82.0 0.566 0.0 HOH
 3.732
 CB
 O
PRO B:28 B:40 84.0 0.579 T -67.6 132.0 NA NA NA
3zkn 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:28 A:40 89.0 0.614 T -64.6 126.8 NA NA NA
PRO B:28 B:40 86.0 0.593 T -68.6 126.2 86.0 0.593 0.0 HOH
 3.867
 CB
 O
3zkq 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:28 A:40 79.0 0.545 T -65.5 142.6 79.0 0.545 0.0 HOH
 2.535
 O
 O
3zks 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:28 A:40 74.0 0.51 T -52.4 141.6 74.0 0.51 0.0 HOH
 2.564
 O
 O
4bel 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:28 A:40 78.0 0.538 T -69.4 143.6 78.0 0.538 0.0 HOH
 3.649
 CB
 O
PRO B:28 B:40 76.0 0.524 T -67.6 140.3 NA NA NA
4bfb 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 PRO A:28 A:40 79.0 0.545 T -69.5 145.6 79.0 0.545 0.0 HOH
 3.838
 CG
 O
PRO B:28 B:40 77.0 0.531 T -56.1 124.3 NA NA NA
6jsz 1 Q9Y5Z0 100.0 0.0 X-RAY
 2019-08-28 PRO A:28 A:40 81.0 0.559 T -67.8 136.4 81.0 0.559 0.0 HOH
 2.994
 O
 O
7d5b 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 PRO A:28 A:40 79.0 0.545 T -66.0 141.8 79.0 0.545 0.0 NA
HOH
 4.595
2.596
 N
O
 NA
O
7d5u 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 PRO A:28 A:40 84.0 0.579 T -62.5 138.3 84.0 0.579 0.0 HOH
 3.965
 CG
 O
7n4n 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-10-06 PRO A:28 A:40 83.0 0.572 T -69.7 142.5 83.0 0.572 0.0 HOH
 2.576
 O
 O
3zkg 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 PRO A:28 A:40 84.0 0.579 T -62.1 121.4 84.0 0.579 0.0 HOH
 3.920
 CB
 O
PRO B:28 B:40 86.0 0.593 T -67.6 121.5 NA NA NA
3zki 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 PRO A:28 A:40 81.0 0.559 T -62.8 132.5 81.0 0.559 0.0 HOH
 4.341
 CB
 O
PRO B:28 B:40 82.0 0.566 T -61.7 125.6 NA NA NA
3zkx 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 PRO A:28 A:40 88.0 0.607 T -60.9 138.0 88.0 0.607 0.0 HOH
 4.091
 CB
 O
3zl7 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 PRO A:28 A:40 80.0 0.552 T -67.1 133.5 80.0 0.552 0.0
3zlq 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-01 PRO A:28 A:40 79.0 0.545 T -66.7 137.3 79.0 0.545 0.0
PRO B:28 B:40 76.0 0.524 T -72.7 132.5 76.0 0.524 0.0
2ewy 1 Q9Y5Z0 100.0 0.0 X-RAY
 2006-11-07 PRO A:25 A:40 88.0 0.607 T -75.8 140.6 88.0 0.607 0.0 HOH
 4.800
 N
 O
PRO B:25 B:40 86.0 0.593 T -75.7 140.6 NA NA NA
PRO C:25 C:40 89.0 0.614 T -75.7 140.6 NA NA NA
PRO D:25 D:40 87.0 0.6 T -75.8 140.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9y5z0-f1 1 Q9Y5Z0 100.0 0.0 PRO A:102 A:102 85.0 0.586 T -68.4 130.3