Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 42609541 . G A CCDS13668.1:NM_012105.4:c.503gGc>gAc_NP_036237.2:p.168G>D Homo sapiens beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6uj0 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 GLY A:168 A:106 77.0 1.0 T 69.4 -139.7 77.0 1.0 0.0
GLY B:168 B:106 79.0 1.0 S 65.5 -102.8 NA NA NA
6uj1 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 GLY A:168 A:106 18.0 0.24 T 118.4 -17.4 18.0 0.24 0.0
GLY B:168 B:106 13.0 0.173 T 121.2 -3.6 NA NA NA
3zkm 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 GLY A:94 A:106 22.0 0.293 T 161.2 -68.4 22.0 0.293 0.0 HOH
 5.233
 N
 O
GLY B:94 B:106 15.0 0.2 T 166.4 -53.5 NA NA NA
3zkn 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 GLY A:94 A:106 15.0 0.2 T 159.3 -50.2 NA NA NA
GLY B:94 B:106 21.0 0.28 T 138.2 -55.7 21.0 0.28 0.0 HOH
 5.676
 N
 O
3zkq 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 GLY A:94 A:106 4.0 0.053 T -88.3 -2.5 4.0 0.053 0.0 HOH
 3.249
 N
 O
3zks 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 GLY A:94 A:106 8.0 0.107 T 153.5 -43.1 8.0 0.107 0.0 HOH
 5.471
 C
 O
4bel 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 GLY A:94 A:106 5.0 0.067 T 139.1 -26.4 5.0 0.067 0.0 HOH
 3.668
 O
 O
GLY B:94 B:106 14.0 0.187 T 164.3 -44.9 NA NA NA
4bfb 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 GLY A:94 A:106 20.0 0.267 T 150.6 -44.0 20.0 0.267 0.0 HOH
 5.361
 N
 O
GLY B:94 B:106 25.0 0.333 T 140.3 -47.6 NA NA NA
6jsz 1 Q9Y5Z0 100.0 0.0 X-RAY
 2019-08-28 GLY A:94 A:106 6.0 0.08 T 148.5 -39.6 6.0 0.08 0.0 HOH
 3.197
 N
 O
7d5b 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 GLY A:94 A:106 5.0 0.067 T 148.7 -31.4 5.0 0.067 0.0 HOH
 3.312
 N
 O
7d5u 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 GLY A:94 A:106 21.0 0.28 T 160.7 -67.9 21.0 0.28 0.0 HOH
 5.361
 N
 O
7n4n 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-10-06 GLY A:94 A:106 6.0 0.08 T 144.3 -32.1 6.0 0.08 0.0 HOH
 2.239
 H
 O
3zkg 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 GLY A:94 A:106 18.0 0.24 T 159.8 -64.1 18.0 0.24 0.0 HOH
 5.155
 N
 O
GLY B:94 B:106 14.0 0.187 T 161.5 -81.1 NA NA NA
3zki 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 GLY A:94 A:106 11.0 0.147 T 142.3 -76.1 11.0 0.147 0.0 HOH
 5.208
 N
 O
GLY B:94 B:106 22.0 0.293 T 142.9 -37.9 NA NA NA
3zkx 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 GLY A:94 A:106 21.0 0.28 T 143.6 -55.1 21.0 0.28 0.0 HOH
 3.085
 O
 O
3zl7 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 GLY A:94 A:106 24.0 0.32 S -78.3 -134.0 24.0 0.32 0.0 HOH
 4.526
 C
 O
3zlq 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-01 GLY A:94 A:106 24.0 0.32 T 146.7 -23.6 24.0 0.32 0.0 HOH
 7.770
 N
 O
GLY B:94 B:106 17.0 0.227 T 145.1 -24.7 17.0 0.227 0.0
2ewy 1 Q9Y5Z0 100.0 0.0 X-RAY
 2006-11-07 GLY A:91 A:106 36.0 0.48 T 139.4 -71.8 36.0 0.48 0.0
GLY B:91 B:106 34.0 0.453 T 139.4 -71.8 NA NA NA
GLY C:91 C:106 35.0 0.467 T 139.4 -71.8 NA NA NA
GLY D:91 D:106 35.0 0.467 T 139.4 -71.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9y5z0-f1 1 Q9Y5Z0 100.0 0.0 GLY A:168 A:168 6.0 0.08 T 160.6 -44.0