Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 42617947 . A C CCDS13668.1:NM_012105.4:c.941aAg>aCg_NP_036237.2:p.314K>T Homo sapiens beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6uj0 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 LYS A:314 A:252 120.0 0.6 H -63.3 -41.9 120.0 0.6 0.0 HOH
 7.287
 O
 O
LYS B:314 B:252 131.0 0.655 H -59.1 -48.6 NA NA NA
6uj1 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 LYS A:314 A:252 160.0 0.8 H -82.1 -19.0 160.0 0.8 0.0
LYS B:314 B:252 142.0 0.71 H -61.6 -25.7 NA NA NA
3zkm 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 LYS A:240 A:252 116.0 0.58 H -60.0 -42.4 116.0 0.58 0.0 HOH
 2.655
 O
 O
LYS B:240 B:252 116.0 0.58 H -61.8 -38.7 NA NA NA
3zkn 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 LYS A:240 A:252 114.0 0.57 H -62.8 -40.8 NA NA NA
LYS B:240 B:252 108.0 0.54 H -60.0 -42.0 108.0 0.54 0.0 HOH
 2.703
 O
 O
3zkq 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 LYS A:240 A:252 115.0 0.575 H -61.8 -43.4 115.0 0.575 0.0 HOH
 2.736
 O
 O
3zks 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 LYS A:240 A:252 119.0 0.595 H -58.3 -40.9 119.0 0.595 0.0 HOH
 7.339
 O
 O
4bel 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 LYS A:240 A:252 118.0 0.59 H -65.0 -40.3 118.0 0.59 0.0 HOH
 2.634
 O
 O
LYS B:240 B:252 122.0 0.61 H -63.4 -43.0 NA NA NA
4bfb 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 LYS A:240 A:252 119.0 0.595 H -65.9 -40.7 119.0 0.595 0.0 HOH
 2.758
 NZ
 O
LYS B:240 B:252 123.0 0.615 H -64.2 -39.4 NA NA NA
6jsz 1 Q9Y5Z0 100.0 0.0 X-RAY
 2019-08-28 LYS A:240 A:252 120.0 0.6 H -65.4 -41.1 120.0 0.6 0.0 HOH
 2.771
 N
 O
7d5b 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 LYS A:240 A:252 113.0 0.565 H -63.6 -37.8 113.0 0.565 0.0 HOH
 2.727
 O
 O
7d5u 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 LYS A:240 A:252 116.0 NA H -65.1 -43.4 116.0 NA NA HOH
 2.834
 N
 O
7n4n 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-10-06 LYS A:240 A:252 118.0 0.59 H -58.6 -38.9 118.0 0.59 0.0 HOH
 1.911
 H
 O
3zkg 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 LYS A:240 A:252 125.0 0.625 H -56.1 -46.7 125.0 0.625 0.0 HOH
 2.837
 N
 O
LYS B:240 B:252 113.0 0.565 H -53.3 -44.5 NA NA NA
3zki 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 LYS A:240 A:252 134.0 0.67 H -52.7 -47.0 134.0 0.67 0.0 HOH
 2.961
 N
 O
LYS B:240 B:252 137.0 0.685 H -51.3 -42.7 NA NA NA
3zkx 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 LYS A:240 A:252 122.0 0.61 H -62.5 -42.8 122.0 0.61 0.0 HOH
 2.768
 O
 O
3zl7 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 LYS A:240 A:252 155.0 0.775 H -74.4 -29.6 155.0 0.775 0.0
3zlq 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-01 LYS A:240 A:252 113.0 0.565 H -47.3 -46.8 113.0 0.565 0.0 HOH
 4.416
 CB
 O
LYS B:240 B:252 132.0 0.66 H -66.1 -41.7 132.0 0.66 0.0
2ewy 1 Q9Y5Z0 100.0 0.0 X-RAY
 2006-11-07 LYS A:237 A:252 125.0 0.625 H -43.7 -40.7 125.0 0.625 0.0 HOH
 8.440
 O
 O
LYS B:237 B:252 128.0 0.64 H -43.7 -40.7 NA NA NA
LYS C:237 C:252 127.0 0.635 H -43.7 -40.7 NA NA NA
LYS D:237 D:252 123.0 0.615 H -43.6 -40.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9y5z0-f1 1 Q9Y5Z0 100.0 0.0 LYS A:314 A:314 113.0 0.565 H -62.7 -38.2