Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 42622731 . C A CCDS13668.1:NM_012105.4:c.1037aCg>aAg_NP_036237.2:p.346T>K Homo sapiens beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6uj0 1 Q9Y5Z0 99.78 0.0 X-RAY
2020-10-07 THR A:346 NA:NA DO NA DO DO DO NA NA NA
THR B:346 B:284 41.0 0.293 E -66.2 143.6 NA NA NA
6uj1 1 Q9Y5Z0 99.78 0.0 X-RAY
2020-10-07 THR A:346 A:284 75.0 0.536 E -58.7 150.0 75.0 0.536 0.0
THR B:346 B:284 97.0 0.693 -55.5 106.8 NA NA NA
3zkm 1 Q9Y5Z0 100.0 0.0 X-RAY
2013-05-29 THR A:272 A:284 72.0 0.514 E -112.6 174.7 72.0 0.514 0.0 DMS
HOH
6.349
2.794
N
N
O
O
THR B:272 B:284 78.0 0.557 E -113.0 172.3 NA NA NA
3zkn 1 Q9Y5Z0 100.0 0.0 X-RAY
2013-05-29 THR A:272 A:284 72.0 0.514 E -116.9 179.4 NA NA NA
THR B:272 B:284 76.0 0.543 E -113.1 174.8 76.0 0.543 0.0 DMS
HOH
6.348
3.337
N
N
C2
O
3zkq 1 Q9Y5Z0 100.0 0.0 X-RAY
2013-05-29 THR A:272 A:284 63.0 0.45 E -58.1 138.2 63.0 0.45 0.0 HOH
8.905
C
O
3zks 1 Q9Y5Z0 100.0 0.0 X-RAY
2013-05-29 THR A:272 A:284 131.0 0.936 -72.8 360.0 131.0 0.936 0.0 HOH
5.835
CG2
O
4bel 1 Q9Y5Z0 100.0 0.0 X-RAY
2013-05-29 THR A:272 A:284 199.0 1.0 59.5 360.0 199.0 1.0 0.0
THR B:272 NA:NA DO NA DO DO DO NA NA NA
4bfb 1 Q9Y5Z0 100.0 0.0 X-RAY
2013-05-29 THR A:272 A:284 67.0 0.479 E -78.9 147.7 67.0 0.479 0.0 HOH
3.869
O
O
THR B:272 B:284 69.0 0.493 E -62.7 150.1 NA NA NA
6jsz 1 Q9Y5Z0 100.0 0.0 X-RAY
2019-08-28 THR A:272 NA:NA DO NA DO DO DO NA NA NA
7d5b 1 Q9Y5Z0 100.0 0.0 X-RAY
2021-03-31 THR A:272 A:284 141.0 1.0 -108.8 134.3 141.0 1.0 0.0
7d5u 1 Q9Y5Z0 100.0 0.0 X-RAY
2021-03-31 THR A:272 A:284 82.0 0.586 E -50.5 120.6 82.0 0.586 0.0
7n4n 1 Q9Y5Z0 100.0 0.0 X-RAY
2021-10-06 THR A:272 A:284 138.0 0.986 -60.8 360.0 138.0 0.986 0.0 HOH
8.574
H
O
3zkg 1 Q9Y5Z0 99.74 0.0 X-RAY
2013-05-29 THR A:272 NA:NA DO NA DO DO DO NA NA NA
THR B:272 NA:NA DO NA DO DO DO NA NA NA
3zki 1 Q9Y5Z0 99.74 0.0 X-RAY
2013-05-29 THR A:272 NA:NA DO NA DO DO DO NA NA NA
THR B:272 B:284 167.0 1.0 -133.0 360.0 NA NA NA
3zkx 1 Q9Y5Z0 99.74 0.0 X-RAY
2013-05-29 THR A:272 A:284 53.0 0.379 -98.8 174.0 30.0 0.214 0.165 C:None:0.164
HOH
2.817
N
O
3zl7 1 Q9Y5Z0 99.74 0.0 X-RAY
2013-05-29 THR A:272 A:284 118.0 0.843 S -61.8 150.6 118.0 0.843 0.0 HOH
7.521
N
O
3zlq 1 Q9Y5Z0 99.74 0.0 X-RAY
2013-05-01 THR A:272 A:284 54.0 0.386 E -70.5 168.9 54.0 0.386 0.0 HOH
5.956
N
O
THR B:272 B:284 54.0 0.386 E -66.2 151.8 54.0 0.386 0.0 HOH
5.964
CG2
O
2ewy 1 Q9Y5Z0 100.0 0.0 X-RAY
2006-11-07 THR A:269 A:284 93.0 0.664 -98.5 -2.6 93.0 0.664 0.0 HOH
2.938
O
O
THR B:269 B:284 92.0 0.657 -98.5 -2.6 NA NA NA
THR C:269 C:284 92.0 0.657 -98.6 -2.6 NA NA NA
THR D:269 D:284 91.0 0.65 -98.6 -2.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9y5z0-f1 1 Q9Y5Z0 100.0 0.0 THR A:346 A:346 53.0 0.379 E -100.1 165.5