Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 44174104 . T A CCDS13690.1:NM_002606.2:c.740cTg>cAg_NP_002597.1:p.247L>Q Homo sapiens phosphodiesterase 9A (PDE9A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4qge 1 K7AGW3 84.65 0.0 X-RAY
 2014-12-10 LEU A:187 A:187 131.0 0.771 S 77.0 104.3 131.0 0.771 0.0 HOH
 3.962
 O
 O
LEU B:187 B:187 135.0 0.794 S -107.6 91.5 135.0 0.794 0.0 HOH
 4.342
 O
 O
4y86 1 O76083 84.65 0.0 X-RAY
 2015-09-16 LEU A:187 A:187 152.0 0.894 S -88.2 123.7 152.0 0.894 0.0 HOH
 4.354
 O
 O
LEU B:187 B:187 94.0 0.553 S -95.1 109.2 94.0 0.553 0.0 HOH
 3.397
 CA
 O
4y87 1 O76083 84.65 0.0 X-RAY
 2015-09-16 LEU A:187 A:187 139.0 0.818 S -96.8 142.0 139.0 0.818 0.0
LEU B:187 B:187 101.0 0.594 S -108.4 116.3 101.0 0.594 0.0
4y8c 1 O76083 84.65 0.0 X-RAY
 2015-09-16 LEU A:187 A:187 141.0 0.829 S -101.6 138.2 141.0 0.829 0.0
LEU B:187 B:187 95.0 0.559 S -99.8 118.0 95.0 0.559 0.0
3qi3 1 O76083 84.49 0.0 X-RAY
 2011-04-27 LEU A:187 A:187 84.0 0.494 S -108.5 97.6 15.0 0.088 0.406 B:O76083:0.406
LEU B:187 B:187 87.0 0.512 S -108.7 96.9 NA NA NA
3qi4 1 O76083 84.49 0.0 X-RAY
 2011-04-27 LEU A:187 A:187 90.0 0.529 S -103.7 92.9 14.0 0.082 0.447 B:O76083:0.447
LEU B:187 B:187 89.0 0.524 S -103.5 102.0 11.0 0.065 0.459 A:O76083:0.459
2yy2 1 O76083 100.0 0.0 X-RAY
 2007-10-30 LEU A:14 A:187 89.0 0.524 S -103.3 106.0 89.0 0.524 0.0
LEU B:14 B:187 93.0 0.547 S -123.9 83.7 93.0 0.547 0.0 HOH
 2.768
 O
 O
2hd1 1 Q53Y40 100.0 0.0 X-RAY
 2006-06-27 LEU A:7 A:187 89.0 0.524 S -98.7 99.5 89.0 0.524 0.0 HOH
 4.104
 O
 O
LEU B:7 B:187 91.0 0.535 S -104.4 92.9 NA NA NA
3k3e 1 O76083 100.0 0.0 X-RAY
 2010-02-16 LEU A:7 A:187 218.0 1.0 360.0 163.1 218.0 1.0 0.0
LEU B:7 B:187 212.0 1.0 360.0 100.1 212.0 1.0 0.0
3k3h 1 O76083 100.0 0.0 X-RAY
 2010-02-16 LEU A:7 A:187 155.0 0.912 -103.2 157.5 155.0 0.912 0.0
LEU B:7 B:187 149.0 0.876 -120.4 86.4 149.0 0.876 0.0
4gh6 1 O76083 100.0 0.0 X-RAY
 2012-10-03 LEU A:7 A:187 97.0 0.571 S -92.2 122.3 22.0 0.129 0.442 B:O76083:0.441
LEU B:7 B:187 90.0 0.529 S -113.1 99.9 14.0 0.082 0.447 A:O76083:0.447
3n3z 1 O76083 99.69 0.0 X-RAY
 2011-04-13 LEU A:7 A:187 95.0 0.559 S -93.1 110.4 17.0 0.1 0.459 B:O76083:0.459
 HOH
 3.997
 O
 O
LEU B:7 B:187 99.0 0.582 S -102.8 114.2 18.0 0.106 0.476 A:O76083:0.476
 HOH
 2.533
 O
 O
3dy8 1 O76083 100.0 0.0 X-RAY
 2008-09-16 LEU A:10 A:187 92.0 0.541 S -92.0 100.3 92.0 0.541 0.0 HOH
 2.715
 O
 O
LEU B:10 B:187 94.0 0.553 S -92.7 102.3 NA NA NA
3dyl 1 O76083 100.0 0.0 X-RAY
 2008-09-16 LEU A:10 A:187 88.0 0.518 S -87.1 97.0 88.0 0.518 0.0 HOH
 2.753
 N
 O
LEU B:10 B:187 92.0 0.541 S -90.8 97.1 NA NA NA
3dyn 1 O76083 100.0 0.0 X-RAY
 2008-09-16 LEU A:10 A:187 89.0 0.524 S -91.3 101.7 89.0 0.524 0.0 HOH
 2.477
 O
 O
LEU B:10 B:187 93.0 0.547 S -91.6 104.5 NA NA NA
3dyq 1 O76083 100.0 0.0 X-RAY
 2008-09-16 LEU A:10 A:187 91.0 0.535 S -91.5 99.9 91.0 0.535 0.0 HOH
 2.638
 O
 O
LEU B:10 B:187 91.0 0.535 S -92.0 104.5 91.0 0.535 0.0 HOH
 2.726
 O
 O
3dys 1 O76083 100.0 0.0 X-RAY
 2008-09-16 LEU A:10 A:187 86.0 0.506 S -84.7 108.7 86.0 0.506 0.0 HOH
 2.427
 O
 O
LEU B:10 B:187 88.0 0.518 S -91.3 103.0 88.0 0.518 0.0 HOH
 2.678
 O
 O
3jsi 1 O76083 100.0 0.0 X-RAY
 2009-12-01 LEU A:10 A:187 95.0 0.559 S -88.4 94.6 95.0 0.559 0.0
LEU B:10 B:187 93.0 0.547 S -88.9 94.5 NA NA NA
3jsw 1 O76083 100.0 0.0 X-RAY
 2009-12-01 LEU A:10 A:187 89.0 0.524 S -86.1 100.5 89.0 0.524 0.0 HOH
 2.686
 O
 O
LEU B:10 B:187 92.0 0.541 S -94.9 102.0 92.0 0.541 0.0 HOH
 2.717
 O
 O
4e90 1 O76083 100.0 0.0 X-RAY
 2013-02-27 LEU A:10 A:187 91.0 0.535 S -95.3 99.7 91.0 0.535 0.0 HOH
 2.683
 O
 O
LEU B:10 B:187 93.0 0.547 S -95.9 99.5 NA NA NA
4g2j 1 O76083 100.0 0.0 X-RAY
 2013-05-29 LEU A:10 A:187 91.0 0.535 S -96.9 99.4 91.0 0.535 0.0 HOH
 2.738
 O
 O
LEU B:10 B:187 92.0 0.541 S -97.2 98.9 NA NA NA
4g2l 1 O76083 100.0 0.0 X-RAY
 2013-05-29 LEU A:10 A:187 83.0 0.488 S -89.0 93.2 83.0 0.488 0.0
LEU B:10 B:187 91.0 0.535 S -94.3 96.6 NA NA NA
6a3n 1 O76083 100.0 0.0 X-RAY
 2019-04-10 LEU A:3 A:187 151.0 0.888 S 71.0 92.1 151.0 0.888 0.0
LEU B:3 B:187 128.0 0.753 S 77.3 114.2 128.0 0.753 0.0 HOH
 8.714
 O
 O
6lzz 1 O76083 100.0 0.0 X-RAY
 2021-02-24 LEU A:3 A:187 200.0 1.0 360.0 173.6 200.0 1.0 0.0 HOH
 2.497
 N
 O
LEU B:3 B:187 160.0 0.941 -82.7 136.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o76083-f1 1 O76083 100.0 0.0 LEU A:247 A:247 84.0 0.494 -84.1 105.7