Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 44174133 . C A CCDS13690.1:NM_002606.2:c.769Cgg>Agg_NP_002597.1:p.257R>R Homo sapiens phosphodiesterase 9A (PDE9A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4qge 1 K7AGW3 84.65 0.0 X-RAY
 2014-12-10 ARG A:197 A:197 79.0 0.351 T -80.6 -7.7 79.0 0.351 0.0 HOH
 2.780
 NE
 O
ARG B:197 B:197 80.0 0.356 T -91.6 -1.5 80.0 0.356 0.0 HOH
 4.690
 NH2
 O
4y86 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:197 A:197 65.0 0.289 T -87.1 -1.9 65.0 0.289 0.0 HOH
 2.671
 O
 O
ARG B:197 B:197 69.0 0.307 T -80.0 1.8 69.0 0.307 0.0 HOH
 2.714
 O
 O
4y87 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:197 A:197 63.0 0.28 T -75.1 -5.7 63.0 0.28 0.0
ARG B:197 B:197 69.0 0.307 T -76.7 -4.7 69.0 0.307 0.0
4y8c 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:197 A:197 63.0 0.28 T -75.1 -14.4 63.0 0.28 0.0
ARG B:197 B:197 57.0 0.253 T -71.1 -13.9 57.0 0.253 0.0
3qi3 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ARG A:197 A:197 67.0 0.298 T -82.3 -15.3 67.0 0.298 0.0
ARG B:197 B:197 86.0 0.382 T -83.8 0.8 NA NA NA
3qi4 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ARG A:197 A:197 62.0 0.276 T -84.5 -16.3 62.0 0.276 0.0
ARG B:197 B:197 81.0 0.36 T -88.5 0.5 81.0 0.36 0.0
2yy2 1 O76083 100.0 0.0 X-RAY
 2007-10-30 ARG A:24 A:197 62.0 0.276 T -89.7 -17.8 62.0 0.276 0.0 HOH
 8.553
 N
 O
ARG B:24 B:197 73.0 0.324 T -75.7 -12.4 73.0 0.324 0.0 HOH
 8.654
 N
 O
2hd1 1 Q53Y40 100.0 0.0 X-RAY
 2006-06-27 ARG A:17 A:197 76.0 0.338 T -85.1 -9.4 76.0 0.338 0.0 HOH
 5.688
 N
 O
ARG B:17 B:197 78.0 0.347 T -83.3 -1.4 NA NA NA
3k3e 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ARG A:17 A:197 68.0 0.302 T -92.5 -16.2 68.0 0.302 0.0
ARG B:17 B:197 82.0 0.364 T -95.6 6.4 82.0 0.364 0.0
3k3h 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ARG A:17 A:197 74.0 0.329 T -86.4 -12.9 74.0 0.329 0.0
ARG B:17 B:197 97.0 0.431 T -93.6 0.6 97.0 0.431 0.0
4gh6 1 O76083 100.0 0.0 X-RAY
 2012-10-03 ARG A:17 A:197 73.0 0.324 T -87.5 -3.5 73.0 0.324 0.0
ARG B:17 B:197 85.0 0.378 T -89.0 6.6 85.0 0.378 0.0
3n3z 1 O76083 99.69 0.0 X-RAY
 2011-04-13 ARG A:17 A:197 80.0 0.356 T -84.2 -13.9 80.0 0.356 0.0 HOH
 6.515
 N
 O
ARG B:17 B:197 88.0 0.391 T -80.4 -2.5 88.0 0.391 0.0 HOH
 2.428
 NE
 O
3dy8 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:20 A:197 87.0 0.387 T -79.9 -4.8 87.0 0.387 0.0 HOH
 2.687
 O
 O
ARG B:20 B:197 92.0 0.409 T -82.1 0.6 NA NA NA
3dyl 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:20 A:197 67.0 0.298 T -83.1 -6.3 67.0 0.298 0.0 HOH
 2.867
 NH1
 O
ARG B:20 B:197 68.0 0.302 T -84.4 -4.9 NA NA NA
3dyn 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:20 A:197 87.0 0.387 T -81.9 -5.5 87.0 0.387 0.0 HOH
 2.637
 NH1
 O
ARG B:20 B:197 89.0 0.396 T -80.9 0.3 NA NA NA
3dyq 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:20 A:197 71.0 0.316 T -84.0 -2.8 71.0 0.316 0.0 HOH
 2.645
 NH1
 O
ARG B:20 B:197 65.0 0.289 T -81.4 -3.1 65.0 0.289 0.0 HOH
 2.424
 O
 O
3dys 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:20 A:197 71.0 0.316 T -82.2 -6.3 71.0 0.316 0.0 HOH
 2.716
 O
 O
ARG B:20 B:197 71.0 0.316 T -84.0 -4.1 71.0 0.316 0.0 HOH
 2.573
 O
 O
3jsi 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ARG A:20 A:197 73.0 0.324 T -77.2 -12.6 73.0 0.324 0.0 HOH
 9.494
 C
 O
ARG B:20 B:197 73.0 0.324 T -77.0 -12.7 NA NA NA
3jsw 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ARG A:20 A:197 62.0 0.276 T -79.3 -5.2 62.0 0.276 0.0 HOH
 2.678
 O
 O
ARG B:20 B:197 85.0 0.378 T -89.9 -1.1 85.0 0.378 0.0 HOH
 2.417
 O
 O
4e90 1 O76083 100.0 0.0 X-RAY
 2013-02-27 ARG A:20 A:197 82.0 0.364 T -82.3 -9.4 82.0 0.364 0.0 HOH
 2.630
 O
 O
ARG B:20 B:197 77.0 0.342 T -81.9 -9.2 NA NA NA
4g2j 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ARG A:20 A:197 68.0 0.302 T -77.7 -11.0 68.0 0.302 0.0 HOH
 2.772
 O
 O
ARG B:20 B:197 84.0 0.373 T -77.9 -10.6 NA NA NA
4g2l 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ARG A:20 A:197 68.0 0.302 T -84.4 -8.5 68.0 0.302 0.0
ARG B:20 B:197 79.0 0.351 T -88.6 -2.0 NA NA NA
6a3n 1 O76083 100.0 0.0 X-RAY
 2019-04-10 ARG A:13 A:197 75.0 0.333 T -78.0 -0.4 75.0 0.333 0.0 HOH
 2.642
 NH1
 O
ARG B:13 B:197 65.0 0.289 T -80.4 -8.5 65.0 0.289 0.0 HOH
 4.551
 NH2
 O
6lzz 1 O76083 100.0 0.0 X-RAY
 2021-02-24 ARG A:13 A:197 62.0 0.276 T -99.2 -4.6 62.0 0.276 0.0 HOH
 8.200
 NH2
 O
ARG B:13 B:197 66.0 0.293 T -94.4 8.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o76083-f1 1 O76083 100.0 0.0 ARG A:257 A:257 57.0 0.253 T -80.8 -0.9