Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 44174170 . A C CCDS13690.1:NM_002606.2:c.806aAt>aCt_NP_002597.1:p.269N>T Homo sapiens phosphodiesterase 9A (PDE9A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4qge 1 K7AGW3 84.65 0.0 X-RAY
 2014-12-10 ASN A:209 A:209 102.0 0.637 H -59.9 -37.8 102.0 0.637 0.0 HOH
 2.577
 ND2
 O
ASN B:209 B:209 62.0 0.388 H -63.4 -30.6 62.0 0.388 0.0 HOH
 7.167
 N
 O
4y86 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ASN A:209 A:209 84.0 0.525 H -59.5 -35.4 84.0 0.525 0.0 HOH
 2.630
 ND2
 O
ASN B:209 B:209 103.0 0.644 H -54.7 -43.1 103.0 0.644 0.0 HOH
 3.167
 OD1
 O
4y87 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ASN A:209 A:209 100.0 0.625 H -45.9 -46.7 100.0 0.625 0.0
ASN B:209 B:209 86.0 0.537 H -36.9 -54.6 86.0 0.537 0.0
4y8c 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ASN A:209 A:209 101.0 0.631 H -58.4 -37.3 101.0 0.631 0.0
ASN B:209 B:209 80.0 0.5 H -56.3 -40.6 80.0 0.5 0.0
3qi3 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ASN A:209 A:209 96.0 0.6 H -64.8 -39.1 71.0 0.444 0.156 B:O76083:0.156
ASN B:209 B:209 90.0 0.562 H -58.0 -49.6 NA NA NA
3qi4 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ASN A:209 A:209 62.0 0.388 H -58.8 -34.2 46.0 0.287 0.101 B:O76083:0.1
ASN B:209 B:209 76.0 0.475 H -55.4 -46.6 58.0 0.362 0.113 A:O76083:0.113
2yy2 1 O76083 100.0 0.0 X-RAY
 2007-10-30 ASN A:36 A:209 99.0 0.619 H -56.2 -50.7 99.0 0.619 0.0 HOH
 9.034
 N
 O
ASN B:36 B:209 89.0 0.556 H -50.5 -57.7 89.0 0.556 0.0 HOH
 2.836
 ND2
 O
2hd1 1 Q53Y40 100.0 0.0 X-RAY
 2006-06-27 ASN A:29 A:209 96.0 0.6 H -56.2 -41.2 96.0 0.6 0.0 HOH
 7.495
 O
 O
ASN B:29 B:209 59.0 0.369 H -64.3 -35.5 NA NA NA
3k3e 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ASN A:29 A:209 89.0 0.556 H -56.0 -42.3 89.0 0.556 0.0
ASN B:29 B:209 118.0 0.738 H -62.8 -52.2 118.0 0.738 0.0
3k3h 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ASN A:29 A:209 76.0 0.475 H -63.0 -28.1 76.0 0.475 0.0
ASN B:29 B:209 88.0 0.55 H -52.4 -46.4 88.0 0.55 0.0
4gh6 1 O76083 100.0 0.0 X-RAY
 2012-10-03 ASN A:29 A:209 68.0 0.425 H -70.0 -37.0 58.0 0.362 0.063 B:O76083:0.062
ASN B:29 B:209 83.0 0.519 H -65.5 -46.2 82.0 0.512 0.007 A:O76083:0.006
3n3z 1 O76083 99.69 0.0 X-RAY
 2011-04-13 ASN A:29 A:209 76.0 0.475 H -58.5 -27.3 58.0 0.362 0.113 B:O76083:0.113
 HOH
 7.164
 OD1
 O
ASN B:29 B:209 75.0 0.469 H -66.1 -37.1 57.0 0.356 0.113 A:O76083:0.113
 HOH
 9.509
 ND2
 O
3dy8 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ASN A:32 A:209 72.0 0.45 H -66.9 -36.6 72.0 0.45 0.0 HOH
 2.945
 O
 O
ASN B:32 B:209 68.0 0.425 H -66.3 -36.6 NA NA NA
3dyl 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ASN A:32 A:209 70.0 0.438 H -65.0 -37.0 70.0 0.438 0.0 HOH
 2.424
 ND2
 O
ASN B:32 B:209 71.0 0.444 H -67.5 -37.3 NA NA NA
3dyn 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ASN A:32 A:209 73.0 0.456 H -68.8 -28.7 73.0 0.456 0.0 HOH
 2.222
 OD1
 O
ASN B:32 B:209 69.0 0.431 H -69.5 -28.4 NA NA NA
3dyq 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ASN A:32 A:209 71.0 0.444 H -67.9 -27.7 71.0 0.444 0.0 HOH
 2.332
 OD1
 O
ASN B:32 B:209 73.0 0.456 H -66.1 -32.9 73.0 0.456 0.0 HOH
 2.394
 CB
 O
3dys 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ASN A:32 A:209 65.0 0.406 H -58.0 -37.5 65.0 0.406 0.0 HOH
 2.628
 O
 O
ASN B:32 B:209 65.0 0.406 H -65.9 -33.5 65.0 0.406 0.0 HOH
 2.819
 OD1
 O
3jsi 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ASN A:32 A:209 89.0 0.556 H -57.6 -36.7 89.0 0.556 0.0
ASN B:32 B:209 88.0 0.55 H -57.8 -36.9 NA NA NA
3jsw 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ASN A:32 A:209 102.0 0.637 H -58.9 -39.3 102.0 0.637 0.0 HOH
 3.013
 N
 O
ASN B:32 B:209 68.0 0.425 H -65.4 -36.4 68.0 0.425 0.0 HOH
 3.095
 OD1
 O
4e90 1 O76083 100.0 0.0 X-RAY
 2013-02-27 ASN A:32 A:209 67.0 0.419 H -62.8 -35.1 67.0 0.419 0.0 HOH
 2.965
 OD1
 O
ASN B:32 B:209 64.0 0.4 H -63.3 -34.8 NA NA NA
4g2j 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ASN A:32 A:209 96.0 0.6 H -58.1 -35.6 96.0 0.6 0.0 HOH
 2.781
 OD1
 O
ASN B:32 B:209 63.0 0.394 H -58.0 -36.1 NA NA NA
4g2l 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ASN A:32 A:209 99.0 0.619 H -62.0 -40.2 99.0 0.619 0.0
ASN B:32 B:209 72.0 0.45 H -67.3 -34.2 NA NA NA
6a3n 1 O76083 100.0 0.0 X-RAY
 2019-04-10 ASN A:25 A:209 87.0 0.544 H -37.4 -57.0 87.0 0.544 0.0 HOH
 7.143
 N
 O
ASN B:25 B:209 100.0 0.625 H -59.6 -38.2 100.0 0.625 0.0 HOH
 6.314
 OD1
 O
6lzz 1 O76083 100.0 0.0 X-RAY
 2021-02-24 ASN A:25 A:209 119.0 0.744 H -53.3 -49.2 119.0 0.744 0.0 HOH
 4.309
 O
 O
ASN B:25 B:209 97.0 0.606 H -60.0 -53.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o76083-f1 1 O76083 100.0 0.0 ASN A:269 A:269 64.0 0.4 H -67.9 -30.2