Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 44179112 . C A CCDS13690.1:NM_002606.2:c.814Ctg>Atg_NP_002597.1:p.272L>M Homo sapiens phosphodiesterase 9A (PDE9A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4qge 1 K7AGW3 84.65 0.0 X-RAY
 2014-12-10 LEU A:212 A:212 18.0 0.106 H -62.2 -41.3 18.0 0.106 0.0 HOH
 6.887
 CD1
 O
LEU B:212 B:212 28.0 0.165 H -61.3 -44.7 28.0 0.165 0.0 HOH
 7.516
 O
 O
4y86 1 O76083 84.65 0.0 X-RAY
 2015-09-16 LEU A:212 A:212 19.0 0.112 H -59.3 -44.3 19.0 0.112 0.0 HOH
 3.786
 CB
 O
LEU B:212 B:212 20.0 0.118 H -60.7 -44.6 20.0 0.118 0.0 HOH
 3.619
 CD1
 O
4y87 1 O76083 84.65 0.0 X-RAY
 2015-09-16 LEU A:212 A:212 19.0 0.112 H -65.2 -39.3 19.0 0.112 0.0
LEU B:212 B:212 28.0 0.165 H -68.3 -45.8 28.0 0.165 0.0
4y8c 1 O76083 84.65 0.0 X-RAY
 2015-09-16 LEU A:212 A:212 17.0 0.1 H -60.1 -39.0 17.0 0.1 0.0
LEU B:212 B:212 25.0 0.147 H -63.1 -41.3 25.0 0.147 0.0
3qi3 1 O76083 84.49 0.0 X-RAY
 2011-04-27 LEU A:212 A:212 22.0 0.129 H -59.4 -41.3 18.0 0.106 0.023 B:O76083:0.024
LEU B:212 B:212 25.0 0.147 H -65.6 -36.3 NA NA NA
3qi4 1 O76083 84.49 0.0 X-RAY
 2011-04-27 LEU A:212 A:212 23.0 0.135 H -60.7 -39.0 20.0 0.118 0.017 B:O76083:0.018
LEU B:212 B:212 27.0 0.159 H -63.5 -37.3 27.0 0.159 0.0
2yy2 1 O76083 100.0 0.0 X-RAY
 2007-10-30 LEU A:39 A:212 16.0 0.094 H -62.2 -37.2 16.0 0.094 0.0 HOH
 9.893
 CD2
 O
LEU B:39 B:212 21.0 0.124 H -56.1 -45.0 21.0 0.124 0.0 HOH
 7.520
 CG
 O
2hd1 1 Q53Y40 100.0 0.0 X-RAY
 2006-06-27 LEU A:32 A:212 18.0 0.106 H -63.3 -42.8 18.0 0.106 0.0 HOH
 5.484
 O
 O
LEU B:32 B:212 27.0 0.159 H -62.4 -39.3 NA NA NA
3k3e 1 O76083 100.0 0.0 X-RAY
 2010-02-16 LEU A:32 A:212 2.0 0.012 H -57.5 -36.5 2.0 0.012 0.0
LEU B:32 B:212 25.0 0.147 H -55.1 -33.0 25.0 0.147 0.0
3k3h 1 O76083 100.0 0.0 X-RAY
 2010-02-16 LEU A:32 A:212 15.0 0.088 H -55.7 -41.9 15.0 0.088 0.0
LEU B:32 B:212 6.0 0.035 H -60.2 -36.4 6.0 0.035 0.0
4gh6 1 O76083 100.0 0.0 X-RAY
 2012-10-03 LEU A:32 A:212 2.0 0.012 H -57.5 -36.0 2.0 0.012 0.0
LEU B:32 B:212 18.0 0.106 H -64.4 -31.8 18.0 0.106 0.0
3n3z 1 O76083 99.69 0.0 X-RAY
 2011-04-13 LEU A:32 A:212 26.0 0.153 H -63.7 -43.9 26.0 0.153 0.0
LEU B:32 B:212 24.0 0.141 H -65.0 -31.8 24.0 0.141 0.0
3dy8 1 O76083 100.0 0.0 X-RAY
 2008-09-16 LEU A:35 A:212 27.0 0.159 H -62.2 -39.3 27.0 0.159 0.0 HOH
 2.965
 O
 O
LEU B:35 B:212 25.0 0.147 H -60.0 -40.9 NA NA NA
3dyl 1 O76083 100.0 0.0 X-RAY
 2008-09-16 LEU A:35 A:212 22.0 0.129 H -62.4 -46.2 22.0 0.129 0.0 HOH
 4.467
 CD1
 O
LEU B:35 B:212 23.0 0.135 H -62.1 -45.9 NA NA NA
3dyn 1 O76083 100.0 0.0 X-RAY
 2008-09-16 LEU A:35 A:212 23.0 0.135 H -60.9 -38.6 23.0 0.135 0.0 HOH
 2.918
 O
 O
LEU B:35 B:212 24.0 0.141 H -64.7 -36.3 NA NA NA
3dyq 1 O76083 100.0 0.0 X-RAY
 2008-09-16 LEU A:35 A:212 24.0 0.141 H -63.4 -38.4 24.0 0.141 0.0 HOH
 2.895
 O
 O
LEU B:35 B:212 22.0 0.129 H -62.5 -39.7 22.0 0.129 0.0 HOH
 4.597
 CD1
 O
3dys 1 O76083 100.0 0.0 X-RAY
 2008-09-16 LEU A:35 A:212 23.0 0.135 H -62.7 -43.4 23.0 0.135 0.0 HOH
 3.206
 O
 O
LEU B:35 B:212 26.0 0.153 H -62.7 -41.9 26.0 0.153 0.0 HOH
 3.205
 O
 O
3jsi 1 O76083 100.0 0.0 X-RAY
 2009-12-01 LEU A:35 A:212 24.0 0.141 H -66.9 -38.1 24.0 0.141 0.0 HOH
 8.319
 O
 O
LEU B:35 B:212 24.0 0.141 H -66.7 -38.0 NA NA NA
3jsw 1 O76083 100.0 0.0 X-RAY
 2009-12-01 LEU A:35 A:212 17.0 0.1 H -60.3 -42.2 17.0 0.1 0.0 HOH
 3.053
 O
 O
LEU B:35 B:212 25.0 0.147 H -62.2 -38.7 25.0 0.147 0.0 HOH
 6.735
 CD1
 O
4e90 1 O76083 100.0 0.0 X-RAY
 2013-02-27 LEU A:35 A:212 26.0 0.153 H -62.7 -41.7 26.0 0.153 0.0 HOH
 5.595
 O
 O
LEU B:35 B:212 26.0 0.153 H -61.5 -41.9 NA NA NA
4g2j 1 O76083 100.0 0.0 X-RAY
 2013-05-29 LEU A:35 A:212 18.0 0.106 H -64.1 -40.9 18.0 0.106 0.0 HOH
 2.894
 O
 O
LEU B:35 B:212 23.0 0.135 H -64.2 -40.8 NA NA NA
4g2l 1 O76083 100.0 0.0 X-RAY
 2013-05-29 LEU A:35 A:212 18.0 0.106 H -64.3 -35.1 18.0 0.106 0.0
LEU B:35 B:212 24.0 0.141 H -64.6 -39.5 NA NA NA
6a3n 1 O76083 100.0 0.0 X-RAY
 2019-04-10 LEU A:28 A:212 28.0 0.165 H -61.9 -54.1 28.0 0.165 0.0 HOH
 8.358
 CG
 O
LEU B:28 B:212 18.0 0.106 H -57.3 -45.2 18.0 0.106 0.0 HOH
 3.426
 CD1
 O
6lzz 1 O76083 100.0 0.0 X-RAY
 2021-02-24 LEU A:28 A:212 14.0 0.082 H -61.6 -31.7 14.0 0.082 0.0 HOH
 7.253
 C
 O
LEU B:28 B:212 25.0 0.147 H -52.7 -44.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o76083-f1 1 O76083 100.0 0.0 LEU A:272 A:272 0.0 0.0 H -58.2 -42.2