Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 44182227 . C A CCDS13690.1:NM_002606.2:c.1120Cgc>Agc_NP_002597.1:p.374R>S Homo sapiens phosphodiesterase 9A (PDE9A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4qge 1 K7AGW3 84.65 0.0 X-RAY
 2014-12-10 ARG A:314 A:314 137.0 0.609 H -64.1 -39.5 69.0 0.307 0.302 B:K7AGW3:0.302
 HOH
 2.869
 NH1
 O
ARG B:314 B:314 119.0 0.529 H -71.2 -37.5 51.0 0.227 0.302 A:K7AGW3:0.302
 HOH
 2.830
 NH1
 O
4y86 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:314 A:314 124.0 0.551 H -61.7 -40.8 60.0 0.267 0.284 B:O76083:0.284
 HOH
 3.013
 NH1
 O
ARG B:314 B:314 119.0 0.529 H -60.9 -42.1 58.0 0.258 0.271 A:O76083:0.271
 HOH
 2.789
 NH1
 O
4y87 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:314 A:314 128.0 0.569 H -76.5 -46.9 61.0 0.271 0.298 B:O76083:0.298
ARG B:314 B:314 119.0 0.529 H -73.9 -47.2 49.0 0.218 0.311 A:O76083:0.311
4y8c 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:314 A:314 127.0 0.564 H -60.2 -39.1 63.0 0.28 0.284 B:O76083:0.284
ARG B:314 B:314 120.0 0.533 H -61.8 -37.9 55.0 0.244 0.289 A:O76083:0.289
3qi3 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ARG A:314 A:314 129.0 0.573 H -61.9 -40.7 129.0 0.573 0.0 HOH
 2.697
 NH1
 O
ARG B:314 B:314 131.0 0.582 H -68.0 -38.3 NA NA NA
3qi4 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ARG A:314 A:314 140.0 0.622 H -66.0 -38.4 140.0 0.622 0.0 HOH
 2.905
 NH1
 O
ARG B:314 B:314 131.0 0.582 H -63.9 -39.4 131.0 0.582 0.0 HOH
 2.712
 NH1
 O
2yy2 1 O76083 100.0 0.0 X-RAY
 2007-10-30 ARG A:141 A:314 128.0 0.569 H -65.0 -41.4 65.0 0.289 0.28 B:O76083:0.28
 HOH
 2.871
 NE
 O
ARG B:141 B:314 135.0 0.6 H -63.7 -41.8 68.0 0.302 0.298 A:O76083:0.298
 HOH
 2.767
 NH1
 O
2hd1 1 Q53Y40 100.0 0.0 X-RAY
 2006-06-27 ARG A:134 A:314 137.0 0.609 H -63.2 -38.8 137.0 0.609 0.0 HOH
 2.733
 NH1
 O
ARG B:134 B:314 132.0 0.587 H -62.5 -38.6 NA NA NA
3k3e 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ARG A:134 A:314 153.0 0.68 H -62.4 -35.3 70.0 0.311 0.369 B:O76083:0.369
ARG B:134 B:314 141.0 0.627 H -62.3 -40.9 57.0 0.253 0.374 A:O76083:0.373
3k3h 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ARG A:134 A:314 138.0 0.613 H -60.8 -43.3 65.0 0.289 0.324 B:O76083:0.324
ARG B:134 B:314 133.0 0.591 H -59.7 -40.0 63.0 0.28 0.311 A:O76083:0.311
4gh6 1 O76083 100.0 0.0 X-RAY
 2012-10-03 ARG A:134 A:314 120.0 0.533 H -65.3 -33.8 120.0 0.533 0.0
ARG B:134 B:314 114.0 0.507 H -72.0 -37.4 114.0 0.507 0.0
3n3z 1 O76083 99.69 0.0 X-RAY
 2011-04-13 ARG A:134 A:314 138.0 0.613 H -60.5 -38.9 138.0 0.613 0.0 HOH
 2.703
 NH1
 O
ARG B:134 B:314 121.0 0.538 H -63.6 -38.0 121.0 0.538 0.0 HOH
 4.740
 N
 O
3dy8 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:137 A:314 138.0 0.613 H -57.4 -43.3 138.0 0.613 0.0 HOH
 2.922
 NH1
 O
ARG B:137 B:314 134.0 0.596 H -61.7 -42.0 NA NA NA
3dyl 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:137 A:314 138.0 0.613 H -68.2 -41.5 138.0 0.613 0.0 HOH
 2.740
 NH1
 O
ARG B:137 B:314 138.0 0.613 H -72.0 -35.3 NA NA NA
3dyn 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:137 A:314 141.0 0.627 H -50.3 -46.9 141.0 0.627 0.0 HOH
 2.731
 NH1
 O
ARG B:137 B:314 138.0 0.613 H -58.5 -41.5 NA NA NA
3dyq 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:137 A:314 132.0 0.587 H -58.6 -41.2 67.0 0.298 0.289 B:O76083:0.289
 HOH
 2.502
 NH2
 O
ARG B:137 B:314 125.0 0.556 H -64.6 -35.9 64.0 0.284 0.272 A:O76083:0.271
 HOH
 2.743
 NH1
 O
3dys 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:137 A:314 133.0 0.591 H -58.6 -43.5 71.0 0.316 0.275 B:O76083:0.276
 HOH
 2.822
 NH1
 O
ARG B:137 B:314 131.0 0.582 H -64.0 -41.1 70.0 0.311 0.271 A:O76083:0.271
 HOH
 2.740
 NH1
 O
3jsi 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ARG A:137 A:314 137.0 0.609 H -67.9 -49.3 137.0 0.609 0.0 HOH
 2.951
 NH1
 O
ARG B:137 B:314 137.0 0.609 H -67.9 -49.1 NA NA NA
3jsw 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ARG A:137 A:314 131.0 0.582 H -52.1 -47.1 68.0 0.302 0.28 B:O76083:0.28
 HOH
 2.908
 NH1
 O
ARG B:137 B:314 127.0 0.564 H -60.9 -36.7 63.0 0.28 0.284 A:O76083:0.284
 HOH
 2.841
 NH1
 O
4e90 1 O76083 100.0 0.0 X-RAY
 2013-02-27 ARG A:137 A:314 148.0 0.658 H -62.3 -46.2 148.0 0.658 0.0 HOH
 2.723
 NH1
 O
ARG B:137 B:314 150.0 0.667 H -62.9 -45.8 NA NA NA
4g2j 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ARG A:137 A:314 139.0 0.618 H -61.2 -45.2 139.0 0.618 0.0 HOH
 2.732
 NH1
 O
ARG B:137 B:314 142.0 0.631 H -61.6 -44.8 NA NA NA
4g2l 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ARG A:137 A:314 135.0 0.6 H -61.6 -47.2 135.0 0.6 0.0
ARG B:137 B:314 131.0 0.582 H -69.2 -40.6 NA NA NA
6a3n 1 O76083 100.0 0.0 X-RAY
 2019-04-10 ARG A:130 A:314 132.0 0.587 H -61.2 -46.9 63.0 0.28 0.307 B:O76083:0.307
 HOH
 2.880
 NH1
 O
ARG B:130 B:314 118.0 0.524 H -67.3 -43.0 51.0 0.227 0.297 A:O76083:0.298
 HOH
 3.185
 NH1
 O
6lzz 1 O76083 100.0 0.0 X-RAY
 2021-02-24 ARG A:130 A:314 140.0 0.622 H -71.0 -33.3 140.0 0.622 0.0 HOH
 2.770
 NH1
 O
ARG B:130 B:314 138.0 0.613 H -68.7 -38.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o76083-f1 1 O76083 100.0 0.0 ARG A:374 A:374 134.0 0.596 H -65.1 -39.1