Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 44182266 . G A CCDS13690.1:NM_002606.2:c.1159Gcc>Acc_NP_002597.1:p.387A>T Homo sapiens phosphodiesterase 9A (PDE9A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4qge 1 K7AGW3 84.65 0.0 X-RAY
 2014-12-10 ALA A:327 A:327 25.0 0.217 H -53.9 -48.7 1.0 0.009 0.208 B:K7AGW3:0.209
 HOH
 4.102
 CB
 O
ALA B:327 B:327 24.0 0.209 H -61.9 -44.1 0.0 0.0 0.209 A:K7AGW3:0.209
 HOH
 4.160
 CA
 O
4y86 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ALA A:327 A:327 28.0 0.243 H -57.2 -44.2 1.0 0.009 0.234 B:O76083:0.235
 HOH
 4.048
 CA
 O
ALA B:327 B:327 26.0 0.226 H -62.0 -46.8 0.0 0.0 0.226 A:O76083:0.226
 HOH
 4.133
 CA
 O
4y87 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ALA A:327 A:327 28.0 0.243 H -54.8 -51.1 0.0 0.0 0.243 B:O76083:0.243
ALA B:327 B:327 25.0 0.217 H -56.6 -58.1 1.0 0.009 0.208 A:O76083:0.209
4y8c 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ALA A:327 A:327 27.0 0.235 H -49.5 -51.5 0.0 0.0 0.235 B:O76083:0.235
ALA B:327 B:327 28.0 0.243 H -70.7 -46.6 1.0 0.009 0.234 A:O76083:0.235
3qi3 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ALA A:327 A:327 30.0 0.261 H -56.9 -44.8 30.0 0.261 0.0 HOH
 4.214
 CB
 O
ALA B:327 B:327 26.0 0.226 H -68.2 -40.1 NA NA NA
3qi4 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ALA A:327 A:327 30.0 0.261 H -51.5 -44.8 30.0 0.261 0.0 HOH
 4.052
 CB
 O
ALA B:327 B:327 29.0 0.252 H -64.5 -41.7 29.0 0.252 0.0 HOH
 4.257
 CB
 O
2yy2 1 O76083 100.0 0.0 X-RAY
 2007-10-30 ALA A:154 A:327 27.0 0.235 H -61.8 -51.3 0.0 0.0 0.235 B:O76083:0.235
 HOH
 4.070
 CA
 O
ALA B:154 B:327 28.0 0.243 H -58.0 -50.6 0.0 0.0 0.243 A:O76083:0.243
 HOH
 4.123
 CB
 O
2hd1 1 Q53Y40 100.0 0.0 X-RAY
 2006-06-27 ALA A:147 A:327 31.0 0.27 H -61.3 -43.5 31.0 0.27 0.0 HOH
 4.192
 CB
 O
ALA B:147 B:327 25.0 0.217 H -66.4 -43.0 NA NA NA
3k3e 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ALA A:147 A:327 34.0 0.296 H -64.4 -45.5 2.0 0.017 0.279 B:O76083:0.278
ALA B:147 B:327 27.0 0.235 H -79.8 -43.8 1.0 0.009 0.226 A:O76083:0.226
3k3h 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ALA A:147 A:327 30.0 0.261 H -65.1 -38.5 1.0 0.009 0.252 B:O76083:0.252
ALA B:147 B:327 27.0 0.235 H -68.0 -41.0 0.0 0.0 0.235 A:O76083:0.235
 HOH
 9.891
 N
 O
4gh6 1 O76083 100.0 0.0 X-RAY
 2012-10-03 ALA A:147 A:327 27.0 0.235 H -54.5 -50.1 27.0 0.235 0.0
ALA B:147 B:327 26.0 0.226 H -64.1 -41.0 26.0 0.226 0.0
3n3z 1 O76083 99.69 0.0 X-RAY
 2011-04-13 ALA A:147 A:327 26.0 0.226 H -52.8 -41.5 26.0 0.226 0.0 HOH
 4.194
 CB
 O
ALA B:147 B:327 29.0 0.252 H -61.4 -43.0 29.0 0.252 0.0 HOH
 7.514
 O
 O
3dy8 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ALA A:150 A:327 28.0 0.243 H -63.2 -42.2 28.0 0.243 0.0 HOH
 4.144
 CB
 O
ALA B:150 B:327 27.0 0.235 H -61.3 -42.7 NA NA NA
3dyl 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ALA A:150 A:327 30.0 0.261 H -60.1 -43.3 30.0 0.261 0.0 HOH
 4.407
 CB
 O
ALA B:150 B:327 28.0 0.243 H -59.7 -47.9 NA NA NA
3dyn 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ALA A:150 A:327 28.0 0.243 H -60.8 -40.6 28.0 0.243 0.0 HOH
 4.319
 CB
 O
ALA B:150 B:327 26.0 0.226 H -63.6 -45.8 NA NA NA
3dyq 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ALA A:150 A:327 31.0 0.27 H -57.8 -43.1 1.0 0.009 0.261 B:O76083:0.261
 HOH
 3.938
 CA
 O
ALA B:150 B:327 26.0 0.226 H -63.1 -43.3 0.0 0.0 0.226 A:O76083:0.226
 HOH
 3.904
 CA
 O
3dys 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ALA A:150 A:327 27.0 0.235 H -58.2 -44.3 1.0 0.009 0.226 B:O76083:0.226
 HOH
 4.018
 CA
 O
ALA B:150 B:327 26.0 0.226 H -62.7 -43.7 0.0 0.0 0.226 A:O76083:0.226
 HOH
 3.829
 CA
 O
3jsi 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ALA A:150 A:327 27.0 0.235 H -62.5 -50.4 27.0 0.235 0.0 HOH
 4.392
 CB
 O
ALA B:150 B:327 24.0 0.209 H -62.9 -49.8 NA NA NA
3jsw 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ALA A:150 A:327 30.0 0.261 H -65.7 -45.7 1.0 0.009 0.252 B:O76083:0.252
 HOH
 3.927
 CA
 O
ALA B:150 B:327 27.0 0.235 H -61.3 -44.3 0.0 0.0 0.235 A:O76083:0.235
 HOH
 3.950
 CA
 O
4e90 1 O76083 100.0 0.0 X-RAY
 2013-02-27 ALA A:150 A:327 28.0 0.243 H -61.8 -43.3 28.0 0.243 0.0 HOH
 4.025
 CB
 O
ALA B:150 B:327 25.0 0.217 H -64.8 -43.4 NA NA NA
4g2j 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ALA A:150 A:327 28.0 0.243 H -60.0 -46.2 28.0 0.243 0.0 HOH
 4.165
 CB
 O
ALA B:150 B:327 25.0 0.217 H -60.3 -46.1 NA NA NA
4g2l 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ALA A:150 A:327 29.0 0.252 H -61.8 -51.9 29.0 0.252 0.0
ALA B:150 B:327 28.0 0.243 H -64.1 -47.6 NA NA NA
6a3n 1 O76083 100.0 0.0 X-RAY
 2019-04-10 ALA A:143 A:327 27.0 0.235 H -55.0 -50.4 1.0 0.009 0.226 B:O76083:0.226
 HOH
 4.074
 CB
 O
ALA B:143 B:327 24.0 0.209 H -50.0 -52.1 0.0 0.0 0.209 A:O76083:0.209
 HOH
 4.465
 CB
 O
6lzz 1 O76083 100.0 0.0 X-RAY
 2021-02-24 ALA A:143 A:327 30.0 0.261 H -54.2 -38.0 30.0 0.261 0.0 HOH
 4.064
 CB
 O
ALA B:143 B:327 29.0 0.252 H -73.9 -41.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o76083-f1 1 O76083 100.0 0.0 ALA A:387 A:387 41.0 0.357 H -60.1 -44.9