Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 44182287 . G A CCDS13690.1:NM_002606.2:c.1180Gcc>Acc_NP_002597.1:p.394A>T Homo sapiens phosphodiesterase 9A (PDE9A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4qge 1 K7AGW3 84.65 0.0 X-RAY
 2014-12-10 ALA A:334 A:334 68.0 0.591 H -69.6 -26.0 65.0 0.565 0.026 B:K7AGW3:0.026
 HOH
 3.271
 CB
 O
ALA B:334 B:334 68.0 0.591 H -74.5 -26.8 63.0 0.548 0.043 A:K7AGW3:0.043
 HOH
 3.639
 N
 O
4y86 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ALA A:334 A:334 73.0 0.635 T -78.2 -17.3 70.0 0.609 0.026 B:O76083:0.026
 HOH
 3.473
 CB
 O
ALA B:334 B:334 70.0 0.609 H -85.6 -21.8 66.0 0.574 0.035 A:O76083:0.035
 HOH
 3.488
 N
 O
4y87 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ALA A:334 A:334 68.0 0.591 H -82.8 -32.1 65.0 0.565 0.026 B:O76083:0.026
ALA B:334 B:334 73.0 0.635 H -79.6 -23.1 68.0 0.591 0.044 A:O76083:0.043
4y8c 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ALA A:334 A:334 73.0 0.635 H -79.2 -22.9 69.0 0.6 0.035 B:O76083:0.035
ALA B:334 B:334 71.0 0.617 T -95.3 -11.8 68.0 0.591 0.026 A:O76083:0.026
3qi3 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ALA A:334 A:334 71.0 0.617 H -74.1 -23.7 71.0 0.617 0.0
ALA B:334 B:334 70.0 0.609 T -80.1 -13.6 NA NA NA
3qi4 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ALA A:334 A:334 70.0 0.609 H -74.6 -24.2 70.0 0.609 0.0
ALA B:334 B:334 70.0 0.609 H -81.0 -16.4 70.0 0.609 0.0
2yy2 1 O76083 100.0 0.0 X-RAY
 2007-10-30 ALA A:161 A:334 72.0 0.626 T -82.1 -13.3 70.0 0.609 0.017 B:O76083:0.017
 HOH
 6.973
 CB
 O
ALA B:161 B:334 70.0 0.609 T -100.9 -8.7 66.0 0.574 0.035 A:O76083:0.035
 HOH
 6.623
 N
 O
2hd1 1 Q53Y40 100.0 0.0 X-RAY
 2006-06-27 ALA A:154 A:334 73.0 0.635 T -74.3 -17.8 73.0 0.635 0.0 HOH
 3.475
 N
 O
ALA B:154 B:334 70.0 0.609 T -79.9 -16.1 NA NA NA
3k3e 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ALA A:154 A:334 61.0 0.53 T -75.6 -36.7 57.0 0.496 0.034 B:O76083:0.035
ALA B:154 B:334 68.0 0.591 T -80.8 -41.3 64.0 0.557 0.034 A:O76083:0.035
3k3h 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ALA A:154 A:334 67.0 0.583 T -81.0 -12.2 63.0 0.548 0.035 B:O76083:0.035
ALA B:154 B:334 66.0 0.574 T -93.8 -10.3 62.0 0.539 0.035 A:O76083:0.035
4gh6 1 O76083 100.0 0.0 X-RAY
 2012-10-03 ALA A:154 A:334 70.0 0.609 T -78.1 -19.9 70.0 0.609 0.0
ALA B:154 B:334 69.0 0.6 T -80.3 -21.4 69.0 0.6 0.0
3n3z 1 O76083 99.69 0.0 X-RAY
 2011-04-13 ALA A:154 A:334 73.0 0.635 T -74.5 -17.2 73.0 0.635 0.0 HOH
 3.678
 N
 O
ALA B:154 B:334 76.0 0.661 H -80.5 -20.5 76.0 0.661 0.0 HOH
 7.057
 N
 O
3dy8 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ALA A:157 A:334 76.0 0.661 T -81.5 -12.0 76.0 0.661 0.0 HOH
 2.466
 O
 O
ALA B:157 B:334 75.0 0.652 T -80.8 -10.9 NA NA NA
3dyl 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ALA A:157 A:334 73.0 0.635 H -80.5 -15.9 73.0 0.635 0.0 HOH
 3.395
 N
 O
ALA B:157 B:334 75.0 0.652 T -81.7 -9.9 NA NA NA
3dyn 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ALA A:157 A:334 75.0 0.652 T -81.8 -12.4 75.0 0.652 0.0 HOH
 2.444
 O
 O
ALA B:157 B:334 72.0 0.626 H -82.8 -11.7 NA NA NA
3dyq 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ALA A:157 A:334 74.0 0.643 H -80.7 -20.3 72.0 0.626 0.017 B:O76083:0.017
 HOH
 3.481
 CA
 O
ALA B:157 B:334 75.0 0.652 H -81.8 -16.1 70.0 0.609 0.043 A:O76083:0.043
 HOH
 3.523
 N
 O
3dys 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ALA A:157 A:334 73.0 0.635 H -80.7 -16.1 69.0 0.6 0.035 B:O76083:0.035
 HOH
 2.684
 O
 O
ALA B:157 B:334 73.0 0.635 T -83.3 -10.1 68.0 0.591 0.044 A:O76083:0.043
 HOH
 3.437
 CB
 O
3jsi 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ALA A:157 A:334 73.0 0.635 H -69.8 -31.2 73.0 0.635 0.0 HOH
 7.053
 N
 O
ALA B:157 B:334 72.0 0.626 H -69.9 -31.3 NA NA NA
3jsw 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ALA A:157 A:334 75.0 0.652 T -81.2 -14.0 73.0 0.635 0.017 B:O76083:0.017
 HOH
 3.611
 N
 O
ALA B:157 B:334 74.0 0.643 H -79.0 -15.6 70.0 0.609 0.034 A:O76083:0.035
 HOH
 3.506
 N
 O
4e90 1 O76083 100.0 0.0 X-RAY
 2013-02-27 ALA A:157 A:334 74.0 0.643 T -79.9 -18.8 74.0 0.643 0.0 HOH
 3.573
 CA
 O
ALA B:157 B:334 73.0 0.635 T -80.4 -18.7 NA NA NA
4g2j 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ALA A:157 A:334 73.0 0.635 H -77.2 -21.1 73.0 0.635 0.0 HOH
 3.445
 CB
 O
ALA B:157 B:334 72.0 0.626 H -77.5 -21.0 NA NA NA
4g2l 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ALA A:157 A:334 74.0 0.643 H -77.2 -25.1 74.0 0.643 0.0
ALA B:157 B:334 72.0 0.626 T -83.1 -18.4 NA NA NA
6a3n 1 O76083 100.0 0.0 X-RAY
 2019-04-10 ALA A:150 A:334 71.0 0.617 H -72.6 -24.9 66.0 0.574 0.043 B:O76083:0.043
 HOH
 4.072
 N
 O
ALA B:150 B:334 77.0 0.67 T -70.1 -21.6 72.0 0.626 0.044 A:O76083:0.043
 HOH
 3.631
 N
 O
6lzz 1 O76083 100.0 0.0 X-RAY
 2021-02-24 ALA A:150 A:334 71.0 0.617 T -73.5 -7.9 71.0 0.617 0.0 HOH
 3.583
 CB
 O
ALA B:150 B:334 73.0 0.635 T -74.0 -27.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o76083-f1 1 O76083 100.0 0.0 ALA A:394 A:394 70.0 0.609 H -76.7 -22.1