Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 44182345 . G A CCDS13690.1:NM_002606.2:c.1238cGa>cAa_NP_002597.1:p.413R>Q Homo sapiens phosphodiesterase 9A (PDE9A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4qge 1 K7AGW3 84.65 0.0 X-RAY
 2014-12-10 ARG A:353 A:353 105.0 0.467 H -55.0 -49.2 18.0 0.08 0.387 B:K7AGW3:0.387
 HOH
 2.855
 NH2
 O
ARG B:353 B:353 102.0 0.453 H -59.4 -47.6 14.0 0.062 0.391 A:K7AGW3:0.391
 HOH
 2.824
 NH2
 O
4y86 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:353 A:353 105.0 0.467 H -55.3 -47.8 16.0 0.071 0.396 B:O76083:0.396
 HOH
 2.879
 NH1
 O
ARG B:353 B:353 104.0 0.462 H -59.1 -49.2 13.0 0.058 0.404 A:O76083:0.404
 HOH
 2.767
 NH1
 O
4y87 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:353 A:353 109.0 0.484 H -49.5 -48.2 9.0 0.04 0.444 B:O76083:0.444
ARG B:353 B:353 107.0 0.476 H -54.1 -49.0 10.0 0.044 0.432 A:O76083:0.431
4y8c 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:353 A:353 105.0 0.467 H -55.7 -48.2 16.0 0.071 0.396 B:O76083:0.396
ARG B:353 B:353 108.0 0.48 H -57.8 -51.3 15.0 0.067 0.413 A:O76083:0.413
3qi3 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ARG A:353 A:353 102.0 0.453 H -58.6 -49.7 102.0 0.453 0.0
ARG B:353 B:353 97.0 0.431 H -58.8 -49.3 NA NA NA
3qi4 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ARG A:353 A:353 102.0 0.453 H -57.8 -46.7 102.0 0.453 0.0
ARG B:353 B:353 100.0 0.444 H -58.5 -48.1 100.0 0.444 0.0
2yy2 1 O76083 100.0 0.0 X-RAY
 2007-10-30 ARG A:180 A:353 105.0 0.467 H -51.9 -50.1 17.0 0.076 0.391 B:O76083:0.391
 HOH
 2.753
 NH1
 O
ARG B:180 B:353 100.0 0.444 H -55.2 -48.6 12.0 0.053 0.391 A:O76083:0.391
 HOH
 2.767
 NH2
 O
2hd1 1 Q53Y40 100.0 0.0 X-RAY
 2006-06-27 ARG A:173 A:353 104.0 0.462 H -55.7 -51.5 104.0 0.462 0.0 HOH
 3.156
 NE
 O
ARG B:173 B:353 99.0 0.44 H -58.9 -49.3 NA NA NA
3k3e 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ARG A:173 A:353 102.0 0.453 H -63.1 -48.2 18.0 0.08 0.373 B:O76083:0.373
ARG B:173 B:353 103.0 0.458 H -50.6 -50.4 4.0 0.018 0.44 A:O76083:0.44
3k3h 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ARG A:173 A:353 103.0 0.458 H -62.7 -50.1 15.0 0.067 0.391 B:O76083:0.391
ARG B:173 B:353 102.0 0.453 H -60.8 -52.0 14.0 0.062 0.391 A:O76083:0.391
4gh6 1 O76083 100.0 0.0 X-RAY
 2012-10-03 ARG A:173 A:353 103.0 0.458 H -63.0 -42.3 103.0 0.458 0.0
ARG B:173 B:353 99.0 0.44 H -60.7 -43.9 99.0 0.44 0.0
3n3z 1 O76083 99.69 0.0 X-RAY
 2011-04-13 ARG A:173 A:353 102.0 0.453 H -52.4 -46.4 102.0 0.453 0.0 HOH
 6.234
 C
 O
ARG B:173 B:353 106.0 0.471 H -54.3 -48.2 106.0 0.471 0.0 HOH
 9.765
 O
 O
3dy8 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:176 A:353 102.0 0.453 H -56.9 -47.9 102.0 0.453 0.0 HOH
 3.302
 NE
 O
ARG B:176 B:353 98.0 0.436 H -57.6 -49.3 NA NA NA
3dyl 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:176 A:353 104.0 0.462 H -61.9 -46.6 104.0 0.462 0.0 HOH
 4.127
 CG
 O
ARG B:176 B:353 100.0 0.444 H -67.0 -50.0 NA NA NA
3dyn 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:176 A:353 102.0 0.453 H -61.8 -46.8 102.0 0.453 0.0 HOH
 3.222
 NE
 O
ARG B:176 B:353 100.0 0.444 H -60.8 -45.5 NA NA NA
3dyq 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:176 A:353 103.0 0.458 H -58.6 -49.5 16.0 0.071 0.387 B:O76083:0.387
 HOH
 2.915
 NH1
 O
ARG B:176 B:353 101.0 0.449 H -61.6 -49.9 11.0 0.049 0.4 A:O76083:0.4
 HOH
 3.078
 NH1
 O
3dys 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:176 A:353 102.0 0.453 H -57.4 -50.6 16.0 0.071 0.382 B:O76083:0.382
 HOH
 2.930
 NH1
 O
ARG B:176 B:353 100.0 0.444 H -62.4 -49.4 13.0 0.058 0.386 A:O76083:0.387
 HOH
 2.955
 NH1
 O
3jsi 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ARG A:176 A:353 104.0 0.462 H -55.8 -51.7 104.0 0.462 0.0 HOH
 9.897
 NH1
 O
ARG B:176 B:353 104.0 0.462 H -56.0 -51.5 NA NA NA
3jsw 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ARG A:176 A:353 101.0 0.449 H -49.2 -53.6 16.0 0.071 0.378 B:O76083:0.378
 HOH
 2.967
 NH1
 O
ARG B:176 B:353 97.0 0.431 H -61.5 -50.2 10.0 0.044 0.387 A:O76083:0.387
 HOH
 2.930
 NH1
 O
4e90 1 O76083 100.0 0.0 X-RAY
 2013-02-27 ARG A:176 A:353 101.0 0.449 H -55.4 -50.7 101.0 0.449 0.0 HOH
 3.346
 NE
 O
ARG B:176 B:353 100.0 0.444 H -56.0 -49.7 NA NA NA
4g2j 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ARG A:176 A:353 104.0 0.462 H -57.4 -52.4 104.0 0.462 0.0 HOH
 3.317
 NE
 O
ARG B:176 B:353 102.0 0.453 H -57.7 -52.0 NA NA NA
4g2l 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ARG A:176 A:353 101.0 0.449 H -66.8 -44.7 101.0 0.449 0.0
ARG B:176 B:353 101.0 0.449 H -70.2 -43.9 NA NA NA
6a3n 1 O76083 100.0 0.0 X-RAY
 2019-04-10 ARG A:169 A:353 108.0 0.48 H -49.0 -55.7 12.0 0.053 0.427 B:O76083:0.427
 HOH
 4.069
 CG
 O
ARG B:169 B:353 106.0 0.471 H -53.7 -50.3 15.0 0.067 0.404 A:O76083:0.404
 HOH
 3.677
 NH2
 O
6lzz 1 O76083 100.0 0.0 X-RAY
 2021-02-24 ARG A:169 A:353 102.0 0.453 H -66.4 -37.5 102.0 0.453 0.0 HOH
 3.839
 CG
 O
ARG B:169 B:353 101.0 0.449 H -48.7 -44.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o76083-f1 1 O76083 100.0 0.0 ARG A:413 A:413 102.0 0.453 H -57.9 -47.9