Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 44185600 . C A CCDS13690.1:NM_002606.2:c.1352aCc>aAc_NP_002597.1:p.451T>N Homo sapiens phosphodiesterase 9A (PDE9A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4qge 1 K7AGW3 84.65 0.0 X-RAY
 2014-12-10 THR A:391 A:391 39.0 0.279 H -61.7 -44.5 39.0 0.279 0.0 HOH
 2.692
 OG1
 O
THR B:391 B:391 37.0 0.264 H -68.0 -42.2 37.0 0.264 0.0 HOH
 2.838
 OG1
 O
4y86 1 O76083 84.65 0.0 X-RAY
 2015-09-16 THR A:391 A:391 46.0 0.329 H -62.1 -45.6 46.0 0.329 0.0 HOH
 2.706
 OG1
 O
THR B:391 B:391 44.0 0.314 H -59.1 -46.4 44.0 0.314 0.0 HOH
 2.731
 OG1
 O
4y87 1 O76083 84.65 0.0 X-RAY
 2015-09-16 THR A:391 A:391 43.0 0.307 H -54.7 -34.7 43.0 0.307 0.0
THR B:391 B:391 40.0 0.286 H -58.3 -45.5 40.0 0.286 0.0
4y8c 1 O76083 84.65 0.0 X-RAY
 2015-09-16 THR A:391 A:391 46.0 0.329 H -59.5 -41.6 46.0 0.329 0.0
THR B:391 B:391 44.0 0.314 H -55.3 -46.3 44.0 0.314 0.0
3qi3 1 O76083 84.49 0.0 X-RAY
 2011-04-27 THR A:391 A:391 47.0 0.336 H -64.3 -49.7 47.0 0.336 0.0
THR B:391 B:391 46.0 0.329 H -62.4 -48.8 NA NA NA
3qi4 1 O76083 84.49 0.0 X-RAY
 2011-04-27 THR A:391 A:391 49.0 0.35 H -61.9 -44.8 49.0 0.35 0.0
THR B:391 B:391 43.0 0.307 H -64.6 -43.3 43.0 0.307 0.0
2yy2 1 O76083 100.0 0.0 X-RAY
 2007-10-30 THR A:218 A:391 44.0 0.314 H -67.4 -39.4 44.0 0.314 0.0 HOH
 4.029
 CG2
 O
THR B:218 B:391 43.0 0.307 H -67.2 -40.6 43.0 0.307 0.0 HOH
 3.768
 CG2
 O
2hd1 1 Q53Y40 100.0 0.0 X-RAY
 2006-06-27 THR A:211 A:391 47.0 0.336 H -62.8 -44.4 47.0 0.336 0.0 HOH
 2.894
 OG1
 O
THR B:211 B:391 43.0 0.307 H -63.6 -44.4 NA NA NA
3k3e 1 O76083 100.0 0.0 X-RAY
 2010-02-16 THR A:211 A:391 51.0 0.364 H -64.2 -37.6 51.0 0.364 0.0
THR B:211 B:391 43.0 0.307 H -64.7 -45.3 43.0 0.307 0.0
3k3h 1 O76083 100.0 0.0 X-RAY
 2010-02-16 THR A:211 A:391 50.0 0.357 H -60.3 -42.5 50.0 0.357 0.0
THR B:211 B:391 47.0 0.336 H -65.2 -47.0 47.0 0.336 0.0
4gh6 1 O76083 100.0 0.0 X-RAY
 2012-10-03 THR A:211 A:391 48.0 0.343 H -66.3 -38.5 48.0 0.343 0.0
THR B:211 B:391 47.0 0.336 H -65.2 -44.4 47.0 0.336 0.0
3n3z 1 O76083 99.69 0.0 X-RAY
 2011-04-13 THR A:211 A:391 48.0 0.343 H -52.4 -42.1 48.0 0.343 0.0 HOH
 4.287
 CG2
 O
THR B:211 B:391 52.0 0.371 H -58.1 -46.7 52.0 0.371 0.0 HOH
 6.864
 CG2
 O
3dy8 1 O76083 100.0 0.0 X-RAY
 2008-09-16 THR A:214 A:391 47.0 0.336 H -63.6 -45.5 47.0 0.336 0.0 HOH
 2.670
 OG1
 O
THR B:214 B:391 53.0 0.379 H -61.5 -48.1 NA NA NA
3dyl 1 O76083 100.0 0.0 X-RAY
 2008-09-16 THR A:214 A:391 48.0 0.343 H -67.9 -39.3 48.0 0.343 0.0 HOH
 2.754
 OG1
 O
THR B:214 B:391 47.0 0.336 H -68.2 -44.1 NA NA NA
3dyn 1 O76083 100.0 0.0 X-RAY
 2008-09-16 THR A:214 A:391 45.0 0.321 H -61.2 -43.4 45.0 0.321 0.0 HOH
 2.647
 OG1
 O
THR B:214 B:391 45.0 0.321 H -62.7 -46.7 NA NA NA
3dyq 1 O76083 100.0 0.0 X-RAY
 2008-09-16 THR A:214 A:391 46.0 0.329 H -64.6 -44.0 46.0 0.329 0.0 HOH
 4.191
 CG2
 O
THR B:214 B:391 45.0 0.321 H -59.3 -46.9 45.0 0.321 0.0 HOH
 3.175
 CG2
 O
3dys 1 O76083 100.0 0.0 X-RAY
 2008-09-16 THR A:214 A:391 48.0 0.343 H -63.8 -40.1 48.0 0.343 0.0 HOH
 2.637
 OG1
 O
THR B:214 B:391 46.0 0.329 H -62.3 -46.7 46.0 0.329 0.0 HOH
 2.884
 OG1
 O
3jsi 1 O76083 100.0 0.0 X-RAY
 2009-12-01 THR A:214 A:391 43.0 0.307 H -62.2 -47.9 43.0 0.307 0.0
THR B:214 B:391 44.0 0.314 H -62.2 -47.9 NA NA NA
3jsw 1 O76083 100.0 0.0 X-RAY
 2009-12-01 THR A:214 A:391 46.0 0.329 H -61.1 -42.6 46.0 0.329 0.0 HOH
 2.809
 OG1
 O
THR B:214 B:391 47.0 0.336 H -58.6 -49.5 47.0 0.336 0.0 HOH
 2.826
 OG1
 O
4e90 1 O76083 100.0 0.0 X-RAY
 2013-02-27 THR A:214 A:391 49.0 0.35 H -62.2 -48.7 49.0 0.35 0.0 HOH
 4.264
 OG1
 O
THR B:214 B:391 48.0 0.343 H -62.6 -49.0 NA NA NA
4g2j 1 O76083 100.0 0.0 X-RAY
 2013-05-29 THR A:214 A:391 47.0 0.336 H -62.4 -45.6 47.0 0.336 0.0 HOH
 2.667
 OG1
 O
THR B:214 B:391 46.0 0.329 H -62.8 -45.7 NA NA NA
4g2l 1 O76083 100.0 0.0 X-RAY
 2013-05-29 THR A:214 A:391 40.0 0.286 H -67.4 -39.3 40.0 0.286 0.0
THR B:214 B:391 42.0 0.3 H -67.5 -42.6 NA NA NA
6a3n 1 O76083 100.0 0.0 X-RAY
 2019-04-10 THR A:207 A:391 39.0 0.279 H -53.6 -43.5 39.0 0.279 0.0 HOH
 2.894
 OG1
 O
THR B:207 B:391 41.0 0.293 H -57.1 -39.8 41.0 0.293 0.0 HOH
 2.741
 OG1
 O
6lzz 1 O76083 100.0 0.0 X-RAY
 2021-02-24 THR A:207 A:391 48.0 0.343 H -60.6 -36.9 48.0 0.343 0.0 HOH
 3.769
 OG1
 O
THR B:207 B:391 37.0 0.264 H -76.9 -37.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o76083-f1 1 O76083 100.0 0.0 THR A:451 A:451 40.0 0.286 H -65.6 -47.6