Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 44188370 . G A CCDS13690.1:NM_002606.2:c.1429Gtg>Atg_NP_002597.1:p.477V>M Homo sapiens phosphodiesterase 9A (PDE9A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4qge 1 K7AGW3 84.65 0.0 X-RAY
 2014-12-10 VAL A:417 A:417 2.0 0.013 H -60.9 -42.7 2.0 0.013 0.0 35O
HOH
 5.435
3.769
 CG2
CG2
 O17
O
VAL B:417 B:417 2.0 0.013 H -59.4 -39.9 2.0 0.013 0.0 35O
HOH
 5.616
3.594
 CG2
CG2
 O17
O
4y86 1 O76083 84.65 0.0 X-RAY
 2015-09-16 VAL A:417 A:417 2.0 0.013 H -67.4 -40.6 2.0 0.013 0.0 49D
HOH
 5.464
3.517
 CG2
CG2
 O17
O
VAL B:417 B:417 3.0 0.019 H -63.0 -39.7 3.0 0.019 0.0 49E
HOH
 5.525
3.639
 CG2
CG2
 O17
O
4y87 1 O76083 84.65 0.0 X-RAY
 2015-09-16 VAL A:417 A:417 2.0 0.013 H -63.8 -36.9 2.0 0.013 0.0 49E
 5.247
 CG2
 O17
VAL B:417 B:417 2.0 0.013 H -56.3 -42.9 2.0 0.013 0.0 49E
 5.862
 CG2
 O17
4y8c 1 O76083 84.65 0.0 X-RAY
 2015-09-16 VAL A:417 A:417 2.0 0.013 H -65.0 -38.5 2.0 0.013 0.0 49D
 5.493
 CG2
 O17
VAL B:417 B:417 2.0 0.013 H -68.0 -37.3 2.0 0.013 0.0 49D
 5.645
 CG2
 O17
3qi3 1 O76083 84.49 0.0 X-RAY
 2011-04-27 VAL A:417 A:417 13.0 0.084 H -59.7 -44.1 13.0 0.084 0.0 PDB
HOH
 4.589
6.298
 CG2
CG2
 O17
O
VAL B:417 B:417 13.0 0.084 H -61.8 -37.4 NA NA NA
3qi4 1 O76083 84.49 0.0 X-RAY
 2011-04-27 VAL A:417 A:417 11.0 0.071 H -61.7 -39.3 11.0 0.071 0.0 IBM
HOH
 5.154
6.533
 CG2
CG2
 O6
O
VAL B:417 B:417 5.0 0.032 H -62.5 -39.2 5.0 0.032 0.0 IBM
HOH
 6.493
4.162
 CG1
N
 N7
O
2yy2 1 O76083 100.0 0.0 X-RAY
 2007-10-30 VAL A:244 A:417 4.0 0.026 H -57.4 -41.0 4.0 0.026 0.0 IBM
HOH
 5.756
3.497
 CG2
CG2
 O6
O
VAL B:244 B:417 3.0 0.019 H -63.4 -38.4 3.0 0.019 0.0 IBM
HOH
 6.621
3.201
 CG1
CG2
 N7
O
2hd1 1 Q53Y40 100.0 0.0 X-RAY
 2006-06-27 VAL A:237 A:417 3.0 0.019 H -62.9 -40.5 3.0 0.019 0.0 IBM
HOH
 5.748
3.647
 CG2
CG2
 O6
O
VAL B:237 B:417 2.0 0.013 H -69.7 -41.0 NA NA NA
3k3e 1 O76083 100.0 0.0 X-RAY
 2010-02-16 VAL A:237 A:417 8.0 0.052 H -58.8 -31.7 8.0 0.052 0.0 PDB
HOH
 3.591
6.221
 CG1
CG2
 F5
O
VAL B:237 B:417 14.0 0.09 H -60.1 -33.6 14.0 0.09 0.0 PDB
 4.210
 CG1
 F5
3k3h 1 O76083 100.0 0.0 X-RAY
 2010-02-16 VAL A:237 A:417 14.0 0.09 H -59.2 -45.1 14.0 0.09 0.0 BYE
HOH
 4.441
6.273
 CG1
CG2
 C20
O
VAL B:237 B:417 13.0 0.084 H -63.3 -39.5 13.0 0.084 0.0 BYE
 4.424
 CG1
 C20
4gh6 1 O76083 100.0 0.0 X-RAY
 2012-10-03 VAL A:237 A:417 5.0 0.032 H -60.0 -39.2 5.0 0.032 0.0 LUO
HOH
 5.255
6.879
 CG2
CG2
 O17
O
VAL B:237 B:417 5.0 0.032 H -57.8 -41.8 5.0 0.032 0.0 LUO
HOH
 5.375
6.906
 CG2
CG2
 O17
O
3n3z 1 O76083 99.69 0.0 X-RAY
 2011-04-13 VAL A:237 A:417 10.0 0.065 H -63.6 -40.9 10.0 0.065 0.0 IBM
HOH
 4.306
3.512
 CG2
CG2
 C8
O
VAL B:237 B:417 13.0 0.084 H -57.1 -44.3 13.0 0.084 0.0 IBM
HOH
 6.431
9.500
 CG1
N
 N7
O
3dy8 1 O76083 100.0 0.0 X-RAY
 2008-09-16 VAL A:240 A:417 4.0 0.026 H -66.7 -45.3 4.0 0.026 0.0 5GP
HOH
 5.312
3.582
 CG2
CG2
 O6
O
VAL B:240 B:417 4.0 0.026 H -66.4 -44.8 NA NA NA
3dyl 1 O76083 100.0 0.0 X-RAY
 2008-09-16 VAL A:240 A:417 3.0 0.019 H -64.7 -35.9 3.0 0.019 0.0 PCG
HOH
 4.993
3.451
 CG2
CG2
 O6
O
VAL B:240 B:417 3.0 0.019 H -64.3 -36.7 NA NA NA
3dyn 1 O76083 100.0 0.0 X-RAY
 2008-09-16 VAL A:240 A:417 2.0 0.013 H -63.4 -41.1 2.0 0.013 0.0 PCG
HOH
 5.184
3.472
 CG2
CG2
 O6
O
VAL B:240 B:417 3.0 0.019 H -66.2 -40.1 NA NA NA
3dyq 1 O76083 100.0 0.0 X-RAY
 2008-09-16 VAL A:240 A:417 2.0 0.013 H -63.6 -43.0 2.0 0.013 0.0 PCG
HOH
 4.984
3.446
 CG2
CG2
 O6
O
VAL B:240 B:417 5.0 0.032 H -62.6 -42.4 5.0 0.032 0.0 IBM
HOH
 6.754
3.322
 CG2
CG2
 N7
O
3dys 1 O76083 100.0 0.0 X-RAY
 2008-09-16 VAL A:240 A:417 4.0 0.026 H -71.6 -42.5 4.0 0.026 0.0 5GP
HOH
 5.235
3.514
 CG2
CG2
 O6
O
VAL B:240 B:417 4.0 0.026 H -62.5 -44.9 4.0 0.026 0.0 IBM
HOH
 6.553
3.595
 CG1
CG2
 N7
O
3jsi 1 O76083 100.0 0.0 X-RAY
 2009-12-01 VAL A:240 A:417 10.0 0.065 H -68.7 -39.0 10.0 0.065 0.0 WTC
HOH
 3.941
8.073
 CG1
CG2
 C21
O
VAL B:240 B:417 9.0 0.058 H -68.6 -39.1 NA NA NA
3jsw 1 O76083 100.0 0.0 X-RAY
 2009-12-01 VAL A:240 A:417 8.0 0.052 H -66.4 -40.2 8.0 0.052 0.0 JAR
HOH
 4.475
3.321
 CG1
CG2
 C28
O
VAL B:240 B:417 9.0 0.058 H -65.9 -44.6 9.0 0.058 0.0 JAR
HOH
 4.777
3.633
 CG1
CG2
 C28
O
4e90 1 O76083 100.0 0.0 X-RAY
 2013-02-27 VAL A:240 A:417 10.0 0.065 H -61.5 -47.0 10.0 0.065 0.0 7RG
HOH
 3.955
3.406
 CG1
CG2
 C29
O
VAL B:240 B:417 10.0 0.065 H -61.2 -49.0 NA NA NA
4g2j 1 O76083 100.0 0.0 X-RAY
 2013-05-29 VAL A:240 A:417 6.0 0.039 H -65.0 -43.6 6.0 0.039 0.0 0WF
HOH
 3.590
3.410
 CG1
CG2
 H2
O
VAL B:240 B:417 6.0 0.039 H -61.9 -46.9 NA NA NA
4g2l 1 O76083 100.0 0.0 X-RAY
 2013-05-29 VAL A:240 A:417 6.0 0.039 H -67.3 -36.1 6.0 0.039 0.0 0WL
 4.519
 CG2
 O27
VAL B:240 B:417 6.0 0.039 H -64.5 -39.5 NA NA NA
6a3n 1 O76083 100.0 0.0 X-RAY
 2019-04-10 VAL A:233 A:417 3.0 0.019 H -67.0 -39.7 3.0 0.019 0.0 9Q9
HOH
 5.513
3.646
 CG2
CG2
 O15
O
VAL B:233 B:417 2.0 0.013 H -68.6 -38.7 2.0 0.013 0.0 9Q9
HOH
 5.588
3.821
 CG2
CG2
 O15
O
6lzz 1 O76083 100.0 0.0 X-RAY
 2021-02-24 VAL A:233 A:417 5.0 0.032 H -58.7 -39.7 5.0 0.032 0.0 EZU
HOH
 5.001
6.364
 CG2
CG2
 O10
O
VAL B:233 B:417 5.0 0.032 H -57.2 -38.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o76083-f1 1 O76083 100.0 0.0 VAL A:477 A:477 2.0 0.013 H -64.5 -39.7