Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 44189173 . C A CCDS13690.1:NM_002606.2:c.1498Ccg>Acg_NP_002597.1:p.500P>T Homo sapiens phosphodiesterase 9A (PDE9A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4qge 1 K7AGW3 84.65 0.0 X-RAY
 2014-12-10 PRO A:440 A:440 74.0 0.51 G -53.5 -46.4 74.0 0.51 0.0 35O
HOH
 7.444
5.721
 C
N
 C20
O
PRO B:440 B:440 78.0 0.538 G -46.5 -40.5 78.0 0.538 0.0 35O
HOH
 7.766
3.323
 O
CD
 C20
O
4y86 1 O76083 84.65 0.0 X-RAY
 2015-09-16 PRO A:440 A:440 79.0 0.545 G -51.2 -36.7 79.0 0.545 0.0 49D
HOH
 6.903
7.004
 O
CD
 C26
O
PRO B:440 B:440 80.0 0.552 G -54.1 -40.0 80.0 0.552 0.0 49E
HOH
 7.820
5.179
 O
O
 C20
O
4y87 1 O76083 84.65 0.0 X-RAY
 2015-09-16 PRO A:440 A:440 71.0 0.49 T -66.3 -22.2 71.0 0.49 0.0 49E
 7.782
 C
 C20
PRO B:440 B:440 81.0 0.559 G -48.7 -39.0 81.0 0.559 0.0 49E
 7.972
 O
 C20
4y8c 1 O76083 84.65 0.0 X-RAY
 2015-09-16 PRO A:440 A:440 84.0 0.579 G -48.0 -41.5 84.0 0.579 0.0 49D
 6.912
 O
 C26
PRO B:440 B:440 85.0 0.586 G -51.7 -36.9 85.0 0.586 0.0 49D
 6.980
 O
 CL
3qi3 1 O76083 84.49 0.0 X-RAY
 2011-04-27 PRO A:440 A:440 81.0 0.559 G -43.0 -43.8 81.0 0.559 0.0 PDB
 7.627
 C
 F6
PRO B:440 B:440 78.0 0.538 G -48.2 -45.2 NA NA NA
3qi4 1 O76083 84.49 0.0 X-RAY
 2011-04-27 PRO A:440 A:440 77.0 0.531 G -48.9 -39.7 77.0 0.531 0.0 IBM
 8.956
 C
 C14
PRO B:440 B:440 84.0 0.579 G -48.2 -42.6 84.0 0.579 0.0 IBM
HOH
 9.124
7.354
 C
C
 C13
O
2yy2 1 O76083 100.0 0.0 X-RAY
 2007-10-30 PRO A:267 A:440 78.0 0.538 G -54.8 -47.7 78.0 0.538 0.0 IBM
 9.732
 C
 C8
PRO B:267 B:440 79.0 0.545 G -60.1 -44.2 79.0 0.545 0.0 IBM
HOH
 8.776
6.495
 C
N
 C13
O
2hd1 1 Q53Y40 100.0 0.0 X-RAY
 2006-06-27 PRO A:260 A:440 78.0 0.538 G -54.1 -40.7 78.0 0.538 0.0 HOH
 6.627
 N
 O
PRO B:260 B:440 79.0 0.545 G -50.0 -41.7 NA NA NA
3k3e 1 O76083 100.0 0.0 X-RAY
 2010-02-16 PRO A:260 A:440 75.0 0.517 G -49.6 -41.6 75.0 0.517 0.0 PDB
 7.393
 C
 C20
PRO B:260 B:440 76.0 0.524 G -58.9 -43.1 76.0 0.524 0.0 PDB
 7.518
 C
 C20
3k3h 1 O76083 100.0 0.0 X-RAY
 2010-02-16 PRO A:260 A:440 81.0 0.559 G -49.7 -39.9 81.0 0.559 0.0 BYE
 7.138
 O
 F7
PRO B:260 B:440 81.0 0.559 G -52.6 -45.2 81.0 0.559 0.0 BYE
 7.346
 C
 F7
4gh6 1 O76083 100.0 0.0 X-RAY
 2012-10-03 PRO A:260 A:440 75.0 0.517 G -49.2 -50.9 75.0 0.517 0.0 LUO
 7.667
 C
 C20
PRO B:260 B:440 79.0 0.545 G -53.8 -38.3 79.0 0.545 0.0 LUO
LUO
 7.937
3.889
 C
O
 C20
C3
3n3z 1 O76083 99.69 0.0 X-RAY
 2011-04-13 PRO A:260 A:440 81.0 0.559 G -45.5 -47.2 81.0 0.559 0.0 IBM
HOH
 9.083
8.233
 O
O
 C14
O
PRO B:260 B:440 79.0 0.545 G -49.8 -43.2 79.0 0.545 0.0 IBM
 8.987
 C
 C14
3dy8 1 O76083 100.0 0.0 X-RAY
 2008-09-16 PRO A:263 A:440 77.0 0.531 G -58.0 -33.4 77.0 0.531 0.0 HOH
 3.300
 CD
 O
PRO B:263 B:440 79.0 0.545 G -52.6 -32.2 NA NA NA
3dyl 1 O76083 100.0 0.0 X-RAY
 2008-09-16 PRO A:263 A:440 75.0 0.517 G -70.1 -27.1 75.0 0.517 0.0 HOH
 5.922
 N
 O
PRO B:263 B:440 79.0 0.545 G -53.2 -35.5 NA NA NA
3dyn 1 O76083 100.0 0.0 X-RAY
 2008-09-16 PRO A:263 A:440 75.0 0.517 G -61.8 -32.6 75.0 0.517 0.0 HOH
 3.275
 CD
 O
PRO B:263 B:440 78.0 0.538 G -51.4 -34.6 NA NA NA
3dyq 1 O76083 100.0 0.0 X-RAY
 2008-09-16 PRO A:263 A:440 75.0 0.517 G -69.7 -32.3 75.0 0.517 0.0 HOH
 2.969
 O
 O
PRO B:263 B:440 81.0 0.559 G -53.4 -30.9 81.0 0.559 0.0 IBM
HOH
 8.689
3.106
 C
CD
 C14
O
3dys 1 O76083 100.0 0.0 X-RAY
 2008-09-16 PRO A:263 A:440 77.0 0.531 G -61.9 -28.5 77.0 0.531 0.0 HOH
 3.199
 CD
 O
PRO B:263 B:440 81.0 0.559 G -54.5 -35.7 81.0 0.559 0.0 IBM
HOH
 8.582
3.272
 C
CD
 C13
O
3jsi 1 O76083 100.0 0.0 X-RAY
 2009-12-01 PRO A:263 A:440 78.0 0.538 T -59.5 -32.6 78.0 0.538 0.0 WTC
 7.368
 O
 C19
PRO B:263 B:440 80.0 0.552 G -56.7 -37.0 NA NA NA
3jsw 1 O76083 100.0 0.0 X-RAY
 2009-12-01 PRO A:263 A:440 74.0 0.51 G -58.5 -35.5 74.0 0.51 0.0 JAR
HOH
 7.571
5.737
 C
N
 C25
O
PRO B:263 B:440 79.0 0.545 G -48.6 -36.7 79.0 0.545 0.0 JAR
HOH
 7.722
3.226
 C
CD
 C18
O
4e90 1 O76083 100.0 0.0 X-RAY
 2013-02-27 PRO A:263 A:440 75.0 0.517 G -53.6 -34.8 75.0 0.517 0.0 7RG
HOH
 7.530
5.782
 C
N
 C16
O
PRO B:263 B:440 79.0 0.545 G -58.0 -32.7 NA NA NA
4g2j 1 O76083 100.0 0.0 X-RAY
 2013-05-29 PRO A:263 A:440 78.0 0.538 G -54.3 -32.5 78.0 0.538 0.0 0WF
HOH
 6.554
3.405
 C
CD
 H19
O
PRO B:263 B:440 78.0 0.538 G -54.1 -31.1 NA NA NA
4g2l 1 O76083 100.0 0.0 X-RAY
 2013-05-29 PRO A:263 A:440 72.0 0.497 G -64.5 -31.9 72.0 0.497 0.0 0WL
 7.383
 C
 C3
PRO B:263 B:440 78.0 0.538 G -68.9 -25.7 NA NA NA
6a3n 1 O76083 100.0 0.0 X-RAY
 2019-04-10 PRO A:256 A:440 84.0 0.579 G -42.9 -45.7 84.0 0.579 0.0 9Q9
HOH
 7.878
3.696
 O
CD
 C20
O
PRO B:256 B:440 82.0 0.566 G -46.6 -40.4 82.0 0.566 0.0 9Q9
HOH
 7.472
8.582
 C
O
 C20
O
6lzz 1 O76083 100.0 0.0 X-RAY
 2021-02-24 PRO A:256 A:440 77.0 0.531 G -51.8 -30.9 77.0 0.531 0.0 EZU
HOH
 8.285
5.652
 C
N
 C20
O
PRO B:256 B:440 80.0 0.552 G -51.2 -42.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o76083-f1 1 O76083 100.0 0.0 PRO A:500 A:500 86.0 0.593 G -57.9 -31.9