Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 44189176 . T A CCDS13690.1:NM_002606.2:c.1501Ttc>Atc_NP_002597.1:p.501F>I Homo sapiens phosphodiesterase 9A (PDE9A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4qge 1 K7AGW3 84.65 0.0 X-RAY
 2014-12-10 PHE A:441 A:441 115.0 0.548 G -64.9 -2.9 115.0 0.548 0.0 35O
HOH
 4.044
4.067
 CD1
CZ
 C20
O
PHE B:441 B:441 122.0 0.581 G -69.6 -5.4 122.0 0.581 0.0 35O
HOH
 3.573
2.631
 CE1
O
 N23
O
4y86 1 O76083 84.65 0.0 X-RAY
 2015-09-16 PHE A:441 A:441 136.0 0.648 G -66.4 -14.1 136.0 0.648 0.0 49D
HOH
 3.042
4.072
 O
CZ
 C26
O
PHE B:441 B:441 125.0 0.595 G -69.3 -5.4 125.0 0.595 0.0 49E
HOH
 3.670
2.996
 CE2
O
 C25
O
4y87 1 O76083 84.65 0.0 X-RAY
 2015-09-16 PHE A:441 A:441 117.0 0.557 T -77.8 3.1 117.0 0.557 0.0 49E
 4.050
 O
 C20
PHE B:441 B:441 128.0 0.61 G -73.9 5.9 128.0 0.61 0.0 49E
HOH
 3.611
9.935
 CE1
CE1
 C25
O
4y8c 1 O76083 84.65 0.0 X-RAY
 2015-09-16 PHE A:441 A:441 138.0 0.657 G -60.5 -17.3 138.0 0.657 0.0 49D
 3.140
 O
 C26
PHE B:441 B:441 141.0 0.671 G -69.7 -8.5 141.0 0.671 0.0 49D
 3.240
 O
 C26
3qi3 1 O76083 84.49 0.0 X-RAY
 2011-04-27 PHE A:441 A:441 106.0 0.505 G -69.3 -3.7 106.0 0.505 0.0 PDB
HOH
 3.758
4.985
 CD1
CE1
 F6
O
PHE B:441 B:441 117.0 0.557 G -68.0 -7.5 NA NA NA
3qi4 1 O76083 84.49 0.0 X-RAY
 2011-04-27 PHE A:441 A:441 112.0 0.533 G -69.0 -6.8 112.0 0.533 0.0 IBM
HOH
 3.656
6.647
 CE1
CE1
 C14
O
PHE B:441 B:441 112.0 0.533 G -68.3 -2.2 112.0 0.533 0.0 IBM
HOH
 3.625
3.975
 CE1
CB
 C11
O
2yy2 1 O76083 100.0 0.0 X-RAY
 2007-10-30 PHE A:268 A:441 116.0 0.552 G -64.2 0.9 116.0 0.552 0.0 IBM
HOH
 5.197
7.931
 CD1
CE1
 N9
O
PHE B:268 B:441 111.0 0.529 G -59.5 -5.9 111.0 0.529 0.0 IBM
HOH
 3.622
5.215
 CE1
CB
 C11
O
2hd1 1 Q53Y40 100.0 0.0 X-RAY
 2006-06-27 PHE A:261 A:441 114.0 0.543 G -68.6 1.8 114.0 0.543 0.0 IBM
HOH
 5.786
6.180
 CE1
CZ
 C13
O
PHE B:261 B:441 114.0 0.543 G -64.8 -8.9 NA NA NA
3k3e 1 O76083 100.0 0.0 X-RAY
 2010-02-16 PHE A:261 A:441 103.0 0.49 G -75.7 -4.1 103.0 0.49 0.0 PDB
HOH
 4.022
4.868
 CB
CE1
 C20
O
PHE B:261 B:441 103.0 0.49 G -67.7 3.0 103.0 0.49 0.0 PDB
HOH
 3.830
9.202
 CD1
CZ
 C20
O
3k3h 1 O76083 100.0 0.0 X-RAY
 2010-02-16 PHE A:261 A:441 102.0 0.486 G -74.0 -6.6 102.0 0.486 0.0 BYE
HOH
 2.953
4.770
 CD1
CE1
 F6
O
PHE B:261 B:441 105.0 0.5 G -66.9 -3.3 105.0 0.5 0.0 BYE
 3.465
 CD1
 F6
4gh6 1 O76083 100.0 0.0 X-RAY
 2012-10-03 PHE A:261 A:441 107.0 0.51 G -67.9 -2.7 107.0 0.51 0.0 LUO
HOH
 4.028
4.673
 CE1
CE1
 O22
O
PHE B:261 B:441 113.0 0.538 G -76.5 3.2 113.0 0.538 0.0 LUO
LUO
HOH
 4.140
3.443
4.179
 CE1
CB
CE1
 C25
O30
O
3n3z 1 O76083 99.69 0.0 X-RAY
 2011-04-13 PHE A:261 A:441 121.0 0.576 G -68.6 -8.5 121.0 0.576 0.0 IBM
HOH
 4.941
7.970
 CD1
CE1
 C14
O
PHE B:261 B:441 118.0 0.562 G -64.3 -11.8 118.0 0.562 0.0 IBM
HOH
 3.624
7.119
 CE1
CE1
 C11
O
3dy8 1 O76083 100.0 0.0 X-RAY
 2008-09-16 PHE A:264 A:441 110.0 0.524 G -71.0 -5.8 110.0 0.524 0.0 5GP
HOH
 5.329
3.305
 CE1
CD2
 O2'
O
PHE B:264 B:441 115.0 0.548 G -66.3 -13.0 NA NA NA
3dyl 1 O76083 100.0 0.0 X-RAY
 2008-09-16 PHE A:264 A:441 117.0 0.557 G -73.6 -3.0 117.0 0.557 0.0 PCG
HOH
 6.161
4.260
 CE1
CZ
 O2'
O
PHE B:264 B:441 112.0 0.533 G -63.6 -14.1 NA NA NA
3dyn 1 O76083 100.0 0.0 X-RAY
 2008-09-16 PHE A:264 A:441 115.0 0.548 G -64.5 -9.3 115.0 0.548 0.0 PCG
HOH
 4.770
2.832
 CE1
O
 O2'
O
PHE B:264 B:441 114.0 0.543 G -68.6 -10.6 NA NA NA
3dyq 1 O76083 100.0 0.0 X-RAY
 2008-09-16 PHE A:264 A:441 111.0 0.529 G -68.7 -7.6 111.0 0.529 0.0 PCG
HOH
 5.340
3.807
 CE1
N
 O2'
O
PHE B:264 B:441 111.0 0.529 G -69.7 -13.5 111.0 0.529 0.0 IBM
HOH
 3.760
2.872
 CE1
N
 C11
O
3dys 1 O76083 100.0 0.0 X-RAY
 2008-09-16 PHE A:264 A:441 111.0 0.529 G -78.6 1.4 111.0 0.529 0.0 5GP
HOH
 6.049
3.673
 CE1
CD2
 O2'
O
PHE B:264 B:441 114.0 0.543 G -67.6 -9.8 114.0 0.543 0.0 IBM
HOH
 3.819
2.843
 CE1
O
 C11
O
3jsi 1 O76083 100.0 0.0 X-RAY
 2009-12-01 PHE A:264 A:441 104.0 0.495 T -75.9 -1.1 104.0 0.495 0.0 WTC
 3.501
 O
 C19
PHE B:264 B:441 102.0 0.486 G -70.9 -1.2 NA NA NA
3jsw 1 O76083 100.0 0.0 X-RAY
 2009-12-01 PHE A:264 A:441 102.0 0.486 G -73.8 -0.9 102.0 0.486 0.0 JAR
HOH
 3.809
3.714
 CD1
CE1
 C25
O
PHE B:264 B:441 110.0 0.524 G -69.8 -8.2 110.0 0.524 0.0 JAR
HOH
 3.420
3.408
 CD1
CD2
 C18
O
4e90 1 O76083 100.0 0.0 X-RAY
 2013-02-27 PHE A:264 A:441 103.0 0.49 G -72.7 -2.4 103.0 0.49 0.0 7RG
HOH
 3.740
3.897
 CE1
CZ
 N18
O
PHE B:264 B:441 106.0 0.505 G -70.5 -4.1 NA NA NA
4g2j 1 O76083 100.0 0.0 X-RAY
 2013-05-29 PHE A:264 A:441 109.0 0.519 G -72.5 -1.2 109.0 0.519 0.0 0WF
HOH
 2.920
3.302
 CD1
CD2
 H19
O
PHE B:264 B:441 106.0 0.505 G -73.0 -6.1 NA NA NA
4g2l 1 O76083 100.0 0.0 X-RAY
 2013-05-29 PHE A:264 A:441 111.0 0.529 G -62.6 -18.4 111.0 0.529 0.0 0WL
 3.503
 CG
 N21
PHE B:264 B:441 114.0 0.543 G -66.6 -9.4 NA NA NA
6a3n 1 O76083 100.0 0.0 X-RAY
 2019-04-10 PHE A:257 A:441 114.0 0.543 G -65.3 -10.6 114.0 0.543 0.0 9Q9
HOH
 3.790
4.395
 CE1
CZ
 C25
O
PHE B:257 B:441 109.0 0.519 G -71.1 -6.6 109.0 0.519 0.0 9Q9
HOH
 3.909
4.957
 CB
CE1
 C20
O
6lzz 1 O76083 100.0 0.0 X-RAY
 2021-02-24 PHE A:257 A:441 109.0 0.519 G -80.0 -0.7 109.0 0.519 0.0 EZU
HOH
 3.545
3.983
 CD1
CZ
 O17
O
PHE B:257 B:441 109.0 0.519 G -68.5 -4.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o76083-f1 1 O76083 100.0 0.0 PHE A:501 A:501 113.0 0.538 G -75.8 -11.5