Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 44189185 . C A CCDS13690.1:NM_002606.2:c.1510Cga>Aga_NP_002597.1:p.504R>R Homo sapiens phosphodiesterase 9A (PDE9A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4qge 1 K7AGW3 84.65 0.0 X-RAY
 2014-12-10 ARG A:444 A:444 123.0 0.547 T -59.1 -17.2 123.0 0.547 0.0 HOH
 8.243
 O
 O
ARG B:444 B:444 108.0 0.48 T -58.2 -28.8 108.0 0.48 0.0 HOH
 6.483
 NH1
 O
4y86 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:444 A:444 115.0 0.511 T -46.0 -30.6 115.0 0.511 0.0 49D
HOH
 6.824
2.992
 N
NH2
 CL
O
ARG B:444 B:444 110.0 0.489 T -56.8 -29.2 110.0 0.489 0.0 HOH
 3.295
 N
 O
4y87 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:444 A:444 122.0 0.542 T -52.0 -24.0 122.0 0.542 0.0
ARG B:444 B:444 113.0 0.502 T -47.0 -38.3 113.0 0.502 0.0
4y8c 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:444 A:444 108.0 0.48 T -53.3 -24.1 108.0 0.48 0.0 49D
 6.828
 N
 CL
ARG B:444 B:444 109.0 0.484 T -67.0 -25.0 109.0 0.484 0.0 49D
 6.936
 N
 CL
3qi3 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ARG A:444 A:444 117.0 0.52 T -48.1 -41.2 117.0 0.52 0.0 PDB
 9.446
 N
 F7
ARG B:444 B:444 118.0 0.524 T -53.7 -51.4 NA NA NA
3qi4 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ARG A:444 A:444 122.0 0.542 T -51.4 -37.0 122.0 0.542 0.0
ARG B:444 B:444 123.0 0.547 T -52.0 -50.0 123.0 0.547 0.0
2yy2 1 O76083 100.0 0.0 X-RAY
 2007-10-30 ARG A:271 A:444 121.0 0.538 T -46.5 -29.7 121.0 0.538 0.0
ARG B:271 B:444 116.0 0.516 T -58.8 -25.3 116.0 0.516 0.0
2hd1 1 Q53Y40 100.0 0.0 X-RAY
 2006-06-27 ARG A:264 A:444 121.0 0.538 T -52.4 -22.4 121.0 0.538 0.0
ARG B:264 B:444 120.0 0.533 T -57.1 -25.2 NA NA NA
3k3e 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ARG A:264 A:444 131.0 0.582 T -45.8 -47.9 131.0 0.582 0.0
ARG B:264 B:444 128.0 0.569 T -52.7 -35.0 128.0 0.569 0.0
3k3h 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ARG A:264 A:444 129.0 0.573 T -45.9 -40.7 129.0 0.573 0.0 BYE
 9.179
 N
 F7
ARG B:264 B:444 123.0 0.547 T -41.4 -41.4 123.0 0.547 0.0 BYE
 9.507
 N
 F7
4gh6 1 O76083 100.0 0.0 X-RAY
 2012-10-03 ARG A:264 A:444 130.0 0.578 T -44.7 -44.7 130.0 0.578 0.0
ARG B:264 B:444 111.0 0.493 T -59.7 -23.5 111.0 0.493 0.0 LUO
 9.050
 N
 C3
3n3z 1 O76083 99.69 0.0 X-RAY
 2011-04-13 ARG A:264 A:444 120.0 0.533 T -39.4 -40.8 120.0 0.533 0.0 HOH
 7.323
 O
 O
ARG B:264 B:444 113.0 0.502 T -43.4 -40.5 113.0 0.502 0.0
3dy8 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:267 A:444 130.0 0.578 T -51.2 -31.1 130.0 0.578 0.0 HOH
 3.321
 NH1
 O
ARG B:267 B:444 122.0 0.542 T -65.8 -20.0 NA NA NA
3dyl 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:267 A:444 126.0 0.56 T -19.2 -40.8 126.0 0.56 0.0 HOH
 3.643
 CD
 O
ARG B:267 B:444 114.0 0.507 T -63.5 -21.0 NA NA NA
3dyn 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:267 A:444 118.0 0.524 T -67.7 -7.8 118.0 0.524 0.0 HOH
 3.559
 N
 O
ARG B:267 B:444 123.0 0.547 T -68.8 -16.9 NA NA NA
3dyq 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:267 A:444 122.0 0.542 T -27.4 -36.7 122.0 0.542 0.0 HOH
 5.423
 O
 O
ARG B:267 B:444 116.0 0.516 T -61.0 -23.8 116.0 0.516 0.0 HOH
 6.852
 N
 O
3dys 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:267 A:444 128.0 0.569 T -50.7 -28.7 128.0 0.569 0.0 HOH
 2.927
 N
 O
ARG B:267 B:444 118.0 0.524 T -65.5 -19.3 118.0 0.524 0.0 HOH
 3.474
 N
 O
3jsi 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ARG A:267 A:444 126.0 0.56 T -55.9 -39.3 126.0 0.56 0.0 WTC
 9.725
 N
 C20
ARG B:267 B:444 117.0 0.52 T -56.3 -27.8 NA NA NA
3jsw 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ARG A:267 A:444 129.0 0.573 T -49.8 -27.2 129.0 0.573 0.0 HOH
 3.322
 N
 O
ARG B:267 B:444 123.0 0.547 T -59.8 -20.2 123.0 0.547 0.0 HOH
 6.243
 NH2
 O
4e90 1 O76083 100.0 0.0 X-RAY
 2013-02-27 ARG A:267 A:444 126.0 0.56 T -52.8 -30.6 126.0 0.56 0.0 HOH
 3.259
 CG
 O
ARG B:267 B:444 122.0 0.542 T -48.1 -27.9 NA NA NA
4g2j 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ARG A:267 A:444 129.0 0.573 T -49.3 -35.0 129.0 0.573 0.0 HOH
 3.246
 CG
 O
ARG B:267 B:444 122.0 0.542 T -56.2 -22.6 NA NA NA
4g2l 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ARG A:267 A:444 120.0 0.533 T -8.1 -58.8 120.0 0.533 0.0
ARG B:267 B:444 110.0 0.489 T -74.3 -15.5 NA NA NA
6a3n 1 O76083 100.0 0.0 X-RAY
 2019-04-10 ARG A:260 A:444 127.0 0.564 T -74.8 -10.9 127.0 0.564 0.0 HOH
 3.427
 NH2
 O
ARG B:260 B:444 126.0 0.56 T -30.1 -46.6 126.0 0.56 0.0 HOH
 2.943
 O
 O
6lzz 1 O76083 100.0 0.0 X-RAY
 2021-02-24 ARG A:260 A:444 133.0 0.591 T -47.3 -35.9 133.0 0.591 0.0 HOH
 2.603
 N
 O
ARG B:260 B:444 114.0 0.507 T -48.1 -45.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o76083-f1 1 O76083 100.0 0.0 ARG A:504 A:504 144.0 0.64 T -55.7 -24.7