Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 44190867 . C A CCDS13690.1:NM_002606.2:c.1645Cgc>Agc_NP_002597.1:p.549R>S Homo sapiens phosphodiesterase 9A (PDE9A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4qge 1 K7AGW3 84.65 0.0 X-RAY
 2014-12-10 ARG A:489 A:489 61.0 0.271 H -62.1 -43.3 61.0 0.271 0.0 HOH
 2.501
 NH1
 O
ARG B:489 B:489 107.0 0.476 H -63.6 -49.6 107.0 0.476 0.0 HOH
 2.427
 NH1
 O
4y86 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:489 A:489 74.0 0.329 H -62.9 -44.5 74.0 0.329 0.0 HOH
 2.676
 NH1
 O
ARG B:489 B:489 79.0 0.351 H -60.8 -46.9 79.0 0.351 0.0 HOH
 2.666
 NH1
 O
4y87 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:489 A:489 73.0 0.324 H -70.5 -47.7 73.0 0.324 0.0
ARG B:489 B:489 77.0 0.342 H -53.9 -47.8 77.0 0.342 0.0
4y8c 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:489 A:489 75.0 0.333 H -68.8 -42.2 75.0 0.333 0.0
ARG B:489 B:489 72.0 0.32 H -62.6 -45.1 72.0 0.32 0.0
3qi3 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ARG A:489 A:489 69.0 0.307 H -65.7 -44.9 69.0 0.307 0.0
ARG B:489 B:489 79.0 0.351 H -53.1 -45.3 NA NA NA
3qi4 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ARG A:489 A:489 74.0 0.329 H -64.9 -45.5 74.0 0.329 0.0
ARG B:489 B:489 69.0 0.307 H -60.8 -39.4 69.0 0.307 0.0
2yy2 1 O76083 100.0 0.0 X-RAY
 2007-10-30 ARG A:316 A:489 81.0 0.36 H -59.8 -51.9 81.0 0.36 0.0 HOH
 3.188
 NH1
 O
ARG B:316 B:489 67.0 0.298 H -56.1 -46.9 67.0 0.298 0.0 HOH
 3.507
 CD
 O
2hd1 1 Q53Y40 100.0 0.0 X-RAY
 2006-06-27 ARG A:309 A:489 71.0 0.316 H -68.3 -43.2 71.0 0.316 0.0 HOH
 2.616
 NE
 O
ARG B:309 B:489 74.0 0.329 H -61.7 -42.3 NA NA NA
3k3e 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ARG A:309 A:489 66.0 0.293 H -59.2 -44.5 66.0 0.293 0.0
ARG B:309 B:489 62.0 0.276 H -56.0 -47.5 62.0 0.276 0.0
3k3h 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ARG A:309 A:489 77.0 0.342 H -62.2 -41.5 77.0 0.342 0.0
ARG B:309 B:489 65.0 0.289 H -56.1 -42.9 65.0 0.289 0.0
4gh6 1 O76083 100.0 0.0 X-RAY
 2012-10-03 ARG A:309 A:489 75.0 0.333 H -60.0 -45.4 75.0 0.333 0.0
ARG B:309 B:489 78.0 0.347 H -59.4 -49.0 78.0 0.347 0.0
3n3z 1 O76083 99.69 0.0 X-RAY
 2011-04-13 ARG A:309 A:489 111.0 0.493 H -57.4 -50.2 111.0 0.493 0.0 HOH
 8.799
 CD
 O
ARG B:309 B:489 75.0 0.333 H -51.5 -45.0 75.0 0.333 0.0 HOH
 6.986
 NH1
 O
3dy8 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:312 A:489 71.0 0.316 H -73.2 -43.0 71.0 0.316 0.0 HOH
 2.481
 NE
 O
ARG B:312 B:489 74.0 0.329 H -59.2 -46.7 NA NA NA
3dyl 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:312 A:489 68.0 0.302 H -67.7 -49.4 68.0 0.302 0.0 HOH
 2.486
 NE
 O
ARG B:312 B:489 67.0 0.298 H -75.6 -49.0 NA NA NA
3dyn 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:312 A:489 73.0 0.324 H -67.1 -43.4 73.0 0.324 0.0 HOH
 2.717
 NE
 O
ARG B:312 B:489 76.0 0.338 H -64.3 -46.8 NA NA NA
3dyq 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:312 A:489 74.0 0.329 H -68.1 -41.1 74.0 0.329 0.0 HOH
 2.668
 NE
 O
ARG B:312 B:489 76.0 0.338 H -63.9 -47.5 76.0 0.338 0.0 HOH
 3.161
 NH1
 O
3dys 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:312 A:489 68.0 0.302 H -64.9 -48.1 68.0 0.302 0.0 HOH
 2.561
 NE
 O
ARG B:312 B:489 71.0 0.316 H -62.6 -43.3 71.0 0.316 0.0 HOH
 2.839
 NH1
 O
3jsi 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ARG A:312 A:489 65.0 0.289 H -70.3 -51.2 65.0 0.289 0.0 HOH
 6.552
 NH1
 O
ARG B:312 B:489 75.0 0.333 H -62.8 -49.0 NA NA NA
3jsw 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ARG A:312 A:489 73.0 0.324 H -69.1 -41.4 73.0 0.324 0.0 HOH
 2.526
 NH1
 O
ARG B:312 B:489 78.0 0.347 H -59.4 -50.6 78.0 0.347 0.0 HOH
 2.675
 NH1
 O
4e90 1 O76083 100.0 0.0 X-RAY
 2013-02-27 ARG A:312 A:489 71.0 0.316 H -73.0 -43.6 71.0 0.316 0.0 HOH
 2.788
 NH1
 O
ARG B:312 B:489 80.0 0.356 H -64.7 -46.2 NA NA NA
4g2j 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ARG A:312 A:489 73.0 0.324 H -71.8 -44.8 73.0 0.324 0.0 HOH
 2.738
 NH1
 O
ARG B:312 B:489 74.0 0.329 H -65.2 -49.9 NA NA NA
4g2l 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ARG A:312 A:489 67.0 0.298 H -68.8 -50.6 67.0 0.298 0.0
ARG B:312 B:489 72.0 0.32 H -56.2 -48.3 NA NA NA
6a3n 1 O76083 100.0 0.0 X-RAY
 2019-04-10 ARG A:305 A:489 73.0 0.324 H -60.3 -39.5 73.0 0.324 0.0 HOH
 5.671
 N
 O
ARG B:305 B:489 78.0 0.347 H -67.8 -47.9 78.0 0.347 0.0 HOH
 2.771
 NH1
 O
6lzz 1 O76083 100.0 0.0 X-RAY
 2021-02-24 ARG A:305 A:489 85.0 0.378 H -63.7 -48.0 49.0 0.218 0.16 B:O76083:0.16
 HOH
 6.968
 O
 O
ARG B:305 B:489 56.0 0.249 H -58.6 -48.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o76083-f1 1 O76083 100.0 0.0 ARG A:549 A:549 96.0 0.427 H -62.5 -46.9