Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 44190886 . G A CCDS13690.1:NM_002606.2:c.1664cGg>cAg_NP_002597.1:p.555R>Q Homo sapiens phosphodiesterase 9A (PDE9A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4qge 1 K7AGW3 84.65 0.0 X-RAY
 2014-12-10 ARG A:495 A:495 185.0 0.822 H -67.4 -36.2 185.0 0.822 0.0 HOH
 2.546
 O
 O
ARG B:495 B:495 139.0 0.618 H -56.4 -42.0 139.0 0.618 0.0 HOH
 2.721
 O
 O
4y86 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:495 A:495 167.0 0.742 H -63.6 -40.2 167.0 0.742 0.0 HOH
 5.969
 N
 O
ARG B:495 B:495 135.0 0.6 H -56.7 -48.6 135.0 0.6 0.0 HOH
 2.414
 O
 O
4y87 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:495 A:495 165.0 0.733 H -60.8 -36.7 165.0 0.733 0.0
ARG B:495 B:495 148.0 0.658 H -55.8 -41.1 148.0 0.658 0.0
4y8c 1 O76083 84.65 0.0 X-RAY
 2015-09-16 ARG A:495 A:495 159.0 0.707 H -64.3 -39.2 159.0 0.707 0.0
ARG B:495 B:495 140.0 0.622 H -55.1 -44.4 140.0 0.622 0.0
3qi3 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ARG A:495 A:495 165.0 0.733 H -59.9 -51.8 165.0 0.733 0.0
ARG B:495 B:495 139.0 0.618 H -55.9 -48.9 NA NA NA
3qi4 1 O76083 84.49 0.0 X-RAY
 2011-04-27 ARG A:495 A:495 166.0 0.738 H -62.7 -61.6 166.0 0.738 0.0
ARG B:495 B:495 136.0 0.604 H -59.6 -46.2 136.0 0.604 0.0
2yy2 1 O76083 100.0 0.0 X-RAY
 2007-10-30 ARG A:322 A:495 156.0 0.693 H -67.2 -53.9 156.0 0.693 0.0
ARG B:322 B:495 151.0 0.671 H -47.3 -45.1 151.0 0.671 0.0
2hd1 1 Q53Y40 100.0 0.0 X-RAY
 2006-06-27 ARG A:315 A:495 164.0 0.729 H -57.6 -44.5 164.0 0.729 0.0 HOH
 4.783
 O
 O
ARG B:315 B:495 178.0 0.791 H -62.7 -41.1 NA NA NA
3k3e 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ARG A:315 A:495 160.0 0.711 H -58.7 -58.7 160.0 0.711 0.0
ARG B:315 B:495 134.0 0.596 H -58.3 -51.8 134.0 0.596 0.0
3k3h 1 O76083 100.0 0.0 X-RAY
 2010-02-16 ARG A:315 A:495 161.0 0.716 H -61.9 -53.3 161.0 0.716 0.0
ARG B:315 B:495 133.0 0.591 H -59.8 -40.7 133.0 0.591 0.0
4gh6 1 O76083 100.0 0.0 X-RAY
 2012-10-03 ARG A:315 A:495 156.0 0.693 H -65.0 -42.4 156.0 0.693 0.0
ARG B:315 B:495 138.0 0.613 H -62.6 -50.7 138.0 0.613 0.0 LUO
 9.490
 N
 C20
3n3z 1 O76083 99.69 0.0 X-RAY
 2011-04-13 ARG A:315 A:495 168.0 0.747 H -58.6 -41.8 168.0 0.747 0.0 HOH
 9.584
 C
 O
ARG B:315 B:495 143.0 0.636 H -48.3 -51.1 143.0 0.636 0.0 HOH
 4.369
 NH2
 O
3dy8 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:318 A:495 162.0 0.72 H -61.0 -42.6 162.0 0.72 0.0 HOH
 2.725
 O
 O
ARG B:318 B:495 138.0 0.613 H -54.9 -45.3 NA NA NA
3dyl 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:318 A:495 165.0 0.733 H -55.7 -37.5 165.0 0.733 0.0 HOH
 5.783
 N
 O
ARG B:318 B:495 147.0 0.653 H -51.8 -46.3 NA NA NA
3dyn 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:318 A:495 155.0 0.689 H -54.4 -44.7 155.0 0.689 0.0 HOH
 2.697
 O
 O
ARG B:318 B:495 141.0 0.627 H -64.6 -42.2 NA NA NA
3dyq 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:318 A:495 163.0 0.724 H -52.6 -38.5 163.0 0.724 0.0 HOH
 6.107
 N
 O
ARG B:318 B:495 147.0 0.653 H -64.1 -34.9 147.0 0.653 0.0 HOH
 7.233
 N
 O
3dys 1 O76083 100.0 0.0 X-RAY
 2008-09-16 ARG A:318 A:495 159.0 0.707 H -62.4 -36.1 159.0 0.707 0.0 HOH
 2.750
 O
 O
ARG B:318 B:495 144.0 0.64 H -55.3 -38.5 144.0 0.64 0.0 HOH
 2.596
 O
 O
3jsi 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ARG A:318 A:495 159.0 0.707 H -56.2 -41.6 159.0 0.707 0.0
ARG B:318 B:495 135.0 0.6 H -58.8 -40.8 NA NA NA
3jsw 1 O76083 100.0 0.0 X-RAY
 2009-12-01 ARG A:318 A:495 174.0 0.773 H -50.4 -37.6 174.0 0.773 0.0 HOH
 3.843
 NH2
 O
ARG B:318 B:495 135.0 0.6 H -68.9 -37.0 135.0 0.6 0.0 HOH
 3.376
 CD
 O
4e90 1 O76083 100.0 0.0 X-RAY
 2013-02-27 ARG A:318 A:495 165.0 0.733 H -55.1 -49.5 165.0 0.733 0.0 HOH
 2.662
 O
 O
ARG B:318 B:495 137.0 0.609 H -59.4 -43.5 NA NA NA
4g2j 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ARG A:318 A:495 157.0 0.698 H -60.5 -37.9 157.0 0.698 0.0 HOH
 2.997
 NH2
 O
ARG B:318 B:495 134.0 0.596 H -63.9 -39.9 NA NA NA
4g2l 1 O76083 100.0 0.0 X-RAY
 2013-05-29 ARG A:318 A:495 175.0 0.778 H -60.7 -34.4 175.0 0.778 0.0
ARG B:318 B:495 147.0 0.653 H -43.6 -45.3 NA NA NA
6a3n 1 O76083 100.0 0.0 X-RAY
 2019-04-10 ARG A:311 A:495 143.0 0.636 H -59.8 -34.9 143.0 0.636 0.0 HOH
 3.420
 CG
 O
ARG B:311 B:495 179.0 0.796 H -59.3 -36.4 179.0 0.796 0.0 HOH
 3.378
 NH2
 O
6lzz 1 O76083 100.0 0.0 X-RAY
 2021-02-24 ARG A:311 A:495 150.0 0.667 H -69.6 -32.7 145.0 0.644 0.023 B:O76083:0.022
 EZU
HOH
 6.617
3.373
 O
NE
 C20
O
ARG B:311 B:495 129.0 0.573 H -60.3 -42.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o76083-f1 1 O76083 100.0 0.0 ARG A:555 A:555 141.0 0.627 H -61.8 -40.7