Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 44190901 . T A CCDS13690.1:NM_002606.2:c.1679aTg>aAg_NP_002597.1:p.560M>K Homo sapiens phosphodiesterase 9A (PDE9A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4qge 1 K7AGW3 84.65 0.0 X-RAY
 2014-12-10 MET A:500 A:500 100.0 0.541 H -60.7 -39.5 100.0 0.541 0.0 HOH
 3.306
 CE
 O
MET B:500 B:500 102.0 0.551 H -67.2 -43.0 102.0 0.551 0.0 HOH
 3.656
 CB
 O
4y86 1 O76083 84.65 0.0 X-RAY
 2015-09-16 MET A:500 A:500 105.0 0.568 H -57.1 -39.8 105.0 0.568 0.0 HOH
 7.352
 O
 O
MET B:500 B:500 108.0 0.584 H -60.5 -39.1 108.0 0.584 0.0 HOH
 4.568
 N
 O
4y87 1 O76083 84.65 0.0 X-RAY
 2015-09-16 MET A:500 A:500 100.0 0.541 H -66.0 -37.4 100.0 0.541 0.0
MET B:500 B:500 101.0 0.546 H -72.1 -47.8 101.0 0.546 0.0
4y8c 1 O76083 84.65 0.0 X-RAY
 2015-09-16 MET A:500 A:500 98.0 0.53 H -68.8 -25.4 98.0 0.53 0.0
MET B:500 B:500 106.0 0.573 H -66.2 -38.7 106.0 0.573 0.0
3qi3 1 O76083 84.49 0.0 X-RAY
 2011-04-27 MET A:500 A:500 107.0 0.578 H -67.9 -29.0 107.0 0.578 0.0
MET B:500 B:500 102.0 0.551 H -62.5 -43.6 NA NA NA
3qi4 1 O76083 84.49 0.0 X-RAY
 2011-04-27 MET A:500 A:500 105.0 0.568 H -55.7 -40.7 105.0 0.568 0.0
MET B:500 B:500 99.0 0.535 H -76.6 -38.6 99.0 0.535 0.0
2yy2 1 O76083 100.0 0.0 X-RAY
 2007-10-30 MET A:327 A:500 105.0 0.568 H -53.5 -44.6 105.0 0.568 0.0
MET B:327 B:500 109.0 0.589 H -68.9 -53.6 109.0 0.589 0.0
2hd1 1 Q53Y40 100.0 0.0 X-RAY
 2006-06-27 MET A:320 A:500 105.0 0.568 H -60.3 -39.4 105.0 0.568 0.0 HOH
 5.906
 N
 O
MET B:320 B:500 104.0 0.562 H -68.4 -41.4 NA NA NA
3k3e 1 O76083 100.0 0.0 X-RAY
 2010-02-16 MET A:320 A:500 103.0 0.557 H -66.6 -35.5 103.0 0.557 0.0
MET B:320 B:500 101.0 0.546 H -52.5 -42.5 101.0 0.546 0.0
3k3h 1 O76083 100.0 0.0 X-RAY
 2010-02-16 MET A:320 A:500 116.0 0.627 H -61.9 -25.7 116.0 0.627 0.0
MET B:320 B:500 97.0 0.524 H -72.8 -45.4 97.0 0.524 0.0
4gh6 1 O76083 100.0 0.0 X-RAY
 2012-10-03 MET A:320 A:500 109.0 0.589 H -78.2 -29.6 109.0 0.589 0.0
MET B:320 B:500 97.0 0.524 H -65.6 -35.5 97.0 0.524 0.0
3n3z 1 O76083 99.69 0.0 X-RAY
 2011-04-13 MET A:320 A:500 107.0 0.578 H -60.8 -43.8 107.0 0.578 0.0 HOH
 6.221
 CB
 O
MET B:320 B:500 112.0 0.605 H -67.9 -41.7 112.0 0.605 0.0
3dy8 1 O76083 100.0 0.0 X-RAY
 2008-09-16 MET A:323 A:500 94.0 0.508 H -58.9 -45.4 94.0 0.508 0.0 HOH
 2.623
 CG
 O
MET B:323 B:500 104.0 0.562 H -64.8 -39.2 NA NA NA
3dyl 1 O76083 100.0 0.0 X-RAY
 2008-09-16 MET A:323 A:500 92.0 0.497 H -73.2 -38.5 92.0 0.497 0.0 HOH
 8.732
 CE
 O
MET B:323 B:500 106.0 0.573 H -76.6 -62.3 NA NA NA
3dyn 1 O76083 100.0 0.0 X-RAY
 2008-09-16 MET A:323 A:500 106.0 0.573 H -65.8 -34.0 106.0 0.573 0.0 HOH
 2.526
 CG
 O
MET B:323 B:500 112.0 0.605 H -68.7 -37.7 NA NA NA
3dyq 1 O76083 100.0 0.0 X-RAY
 2008-09-16 MET A:323 A:500 96.0 0.519 H -64.9 -38.8 96.0 0.519 0.0 HOH
 8.341
 O
 O
MET B:323 B:500 97.0 0.524 H -69.8 -60.3 97.0 0.524 0.0 HOH
 9.815
 CB
 O
3dys 1 O76083 100.0 0.0 X-RAY
 2008-09-16 MET A:323 A:500 98.0 0.53 H -56.3 -40.0 98.0 0.53 0.0 HOH
 3.021
 O
 O
MET B:323 B:500 106.0 0.573 H -64.7 -48.3 106.0 0.573 0.0 HOH
 6.275
 N
 O
3jsi 1 O76083 100.0 0.0 X-RAY
 2009-12-01 MET A:323 A:500 96.0 0.519 H -68.2 -41.9 96.0 0.519 0.0
MET B:323 B:500 105.0 0.568 H -71.0 -51.8 NA NA NA
3jsw 1 O76083 100.0 0.0 X-RAY
 2009-12-01 MET A:323 A:500 106.0 0.573 H -55.8 -55.1 106.0 0.573 0.0 HOH
 6.657
 N
 O
MET B:323 B:500 104.0 0.562 H -64.2 -51.7 104.0 0.562 0.0 HOH
 6.947
 N
 O
4e90 1 O76083 100.0 0.0 X-RAY
 2013-02-27 MET A:323 A:500 110.0 0.595 H -64.0 -49.1 110.0 0.595 0.0 HOH
 4.847
 N
 O
MET B:323 B:500 100.0 0.541 H -71.9 -47.9 NA NA NA
4g2j 1 O76083 100.0 0.0 X-RAY
 2013-05-29 MET A:323 A:500 125.0 0.676 H -71.2 -43.9 125.0 0.676 0.0 HOH
 3.532
 O
 O
MET B:323 B:500 106.0 0.573 H -69.2 -43.7 NA NA NA
4g2l 1 O76083 100.0 0.0 X-RAY
 2013-05-29 MET A:323 A:500 120.0 0.649 H -83.5 -45.9 120.0 0.649 0.0
MET B:323 B:500 104.0 0.562 H -71.1 -68.0 NA NA NA
6a3n 1 O76083 100.0 0.0 X-RAY
 2019-04-10 MET A:316 A:500 118.0 0.638 H -63.0 -35.7 118.0 0.638 0.0 HOH
 3.264
 CE
 O
MET B:316 B:500 105.0 0.568 H -71.0 -29.7 105.0 0.568 0.0 HOH
 6.045
 C
 O
6lzz 1 O76083 100.0 0.0 X-RAY
 2021-02-24 MET A:316 A:500 113.0 0.611 H -65.6 -28.5 35.0 0.189 0.422 B:O76083:0.422
 EZU
HOH
 3.517
4.661
 SD
CE
 C23
O
MET B:316 B:500 129.0 0.697 H -75.7 -23.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o76083-f1 1 O76083 100.0 0.0 MET A:560 A:560 123.0 0.665 H -65.2 -42.7