Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 19950299 . G A CCDS13770.1:NM_000754.3:c.250Gag>Aag_NP_000745.1:p.84E>K Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4pyi 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 GLU A:34 A:84 166.0 0.874 H -51.4 -34.3 166.0 0.874 0.0 HOH
 8.574
 H
 O
4pyj 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 GLU A:34 A:84 152.0 0.8 H -63.6 -44.1 152.0 0.8 0.0 HOH
 6.219
 N
 O
4pyk 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 GLU A:34 A:84 135.0 0.711 H -58.7 -32.3 135.0 0.711 0.0
5lsa 1 P21964 100.0 3e-165 X-RAY
 2016-09-07 GLU A:34 A:84 106.0 0.558 H -67.1 -35.3 106.0 0.558 0.0 CL
HOH
 5.598
2.231
 OE1
OE1
 CL
O
6i3c 1 P21964 99.1 4e-164 X-RAY
 2019-09-18 GLU A:45 A:34 109.0 0.574 H -67.5 -34.5 109.0 0.574 0.0 HOH
 2.450
 OE1
 O
6i3d 1 P21964 99.1 4e-164 X-RAY
 2019-09-18 GLU A:45 A:34 113.0 0.595 H -71.0 -45.2 113.0 0.595 0.0 HOH
 3.166
 O
 O
GLU B:45 B:34 122.0 0.642 H -72.6 -39.3 NA NA NA
4xuc 1 P21964 99.54 1e-161 X-RAY
 2015-04-15 GLU A:37 A:84 112.0 0.589 H -72.6 -35.1 112.0 0.589 0.0 HOH
 2.985
 OE1
 O
4xud 1 P21964 99.54 1e-161 X-RAY
 2015-04-15 GLU A:37 A:84 113.0 0.595 H -71.5 -28.9 113.0 0.595 0.0 HOH
 3.433
 OE2
 O
4xue 1 P21964 100.0 1e-159 X-RAY
 2015-04-15 GLU A:34 B:84 119.0 0.626 H -65.2 -41.3 119.0 0.626 0.0 HOH
 3.563
 O
 O
GLU B:34 A:84 111.0 0.584 H -69.9 -31.4 NA NA NA
3a7e 1 P21964 100.0 1e-159 X-RAY
 2010-09-15 GLU A:36 A:34 122.0 0.642 H -61.0 -40.6 122.0 0.642 0.0 HOH
 3.784
 O
 O
3bwm 1 P21964 100.0 2e-159 X-RAY
 2008-06-03 GLU A:33 A:34 103.0 0.542 H -67.7 -39.5 103.0 0.542 0.0 HOH
 3.310
 O
 O
3bwy 1 Q6ICE6 99.53 5e-159 X-RAY
 2008-06-03 GLU A:33 A:34 112.0 0.589 H -72.5 -39.3 112.0 0.589 0.0 HOH
 2.117
 OE2
 O
3nwe 1 P22734 82.03 6e-135 X-RAY
 2011-08-03 THR A:34 A:34 95.0 0.679 H -89.6 -36.9 95.0 0.679 0.0 CL
HOH
 6.260
3.034
 HG1
HB
 CL
O
3oe4 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 THR A:34 A:34 69.0 0.493 H -72.3 -41.4 69.0 0.493 0.0 HOH
 4.202
 OG1
 O
3oe5 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 THR A:34 A:34 70.0 0.5 H -72.4 -38.4 70.0 0.5 0.0 HOH
 4.062
 OG1
 O
3ozr 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 THR A:34 A:34 94.0 0.671 H -75.5 -42.9 94.0 0.671 0.0 HOH
 6.350
 OG1
 O
3ozs 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 THR A:34 A:34 79.0 0.564 H -74.7 -41.2 79.0 0.564 0.0 HOH
 4.721
 OG1
 O
3ozt 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 THR A:34 A:34 74.0 0.529 H -71.7 -43.3 74.0 0.529 0.0 HOH
 4.501
 OG1
 O
3r6t 1 P22734 82.03 6e-135 X-RAY
 2012-02-01 THR A:34 A:77 95.0 0.679 H -84.8 -40.8 95.0 0.679 0.0 CL
NHE
HOH
 6.317
6.797
2.690
 OG1
O
O
 CL
O1
O
3u81 1 P22734 82.03 6e-135 X-RAY
 2012-02-01 THR A:34 A:34 44.0 0.314 H -65.6 -45.4 44.0 0.314 0.0 HOH
 2.811
 OG1
 O
4pym 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 THR A:34 A:77 46.0 0.329 H -65.0 -45.4 46.0 0.329 0.0 HOH
 2.730
 OG1
 O
4pyn 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 THR A:34 A:77 41.0 0.293 H -63.9 -45.0 41.0 0.293 0.0 HOH
 2.795
 OG1
 O
4pyo 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 THR A:34 A:77 67.0 0.479 H -58.3 -55.9 67.0 0.479 0.0 HOH
 9.636
 N
 O
THR B:34 B:77 80.0 0.571 H -112.8 0.1 NA NA NA
4pyq 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 THR A:34 A:77 45.0 0.321 H -67.7 -45.0 45.0 0.321 0.0 SO4
HOH
 9.901
3.409
 N
OG1
 O4
O
THR B:34 B:77 44.0 0.314 H -60.8 -52.1 44.0 0.314 0.0 HOH
 2.114
 HG1
 O
5lqj 1 P22734 82.03 6e-135 X-RAY
 2016-09-28 THR A:34 A:34 92.0 0.657 H -105.4 -43.2 92.0 0.657 0.0 HOH
 6.799
 OG1
 O
THR B:34 B:34 49.0 0.35 H -86.6 -47.0 NA NA NA
THR C:34 C:34 94.0 0.671 H -95.3 -44.7 NA NA NA
THR D:34 D:34 84.0 0.6 H -74.5 -46.7 NA NA NA
5lqk 1 P22734 82.03 6e-135 X-RAY
 2016-08-31 THR A:34 A:34 95.0 0.679 H -87.7 -32.5 95.0 0.679 0.0 CL
HOH
 6.406
4.921
 OG1
OG1
 CL
O
5lqn 1 P22734 82.03 6e-135 X-RAY
 2016-10-05 THR A:34 A:34 111.0 0.793 H -81.5 -39.1 111.0 0.793 0.0 HOH
 6.763
 OG1
 O
5lr6 1 P22734 82.03 6e-135 X-RAY
 2016-08-31 THR A:34 A:34 118.0 0.843 H -91.8 -39.0 118.0 0.843 0.0 HOH
 3.682
 O
 O
THR B:34 B:34 101.0 0.721 H -76.2 -52.5 NA NA NA
THR C:34 C:34 111.0 0.793 H -81.2 -44.2 NA NA NA
THR D:34 D:34 111.0 0.793 H -90.8 -29.8 NA NA NA
5p8w 1 P22734 82.03 6e-135 X-RAY
 2016-09-07 THR A:34 A:34 93.0 0.664 H -61.8 -47.8 63.0 0.45 0.214 B:P22734:0.214
 DTT
HOH
 6.082
2.482
 N
OG1
 S4
O
THR B:34 B:34 82.0 0.586 H -65.0 -38.9 82.0 0.586 0.0 DTT
NA
HOH
 5.996
3.872
4.962
 N
O
OG1
 S4
NA
O
THR C:34 C:34 65.0 0.464 H -79.0 -26.1 65.0 0.464 0.0 DTT
HOH
 6.004
5.938
 N
CG2
 S4
O
5p8x 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 THR A:34 A:34 99.0 0.707 H -81.3 -42.7 99.0 0.707 0.0 CL
NHE
D1D
HOH
 6.215
6.601
9.927
2.927
 OG1
O
O
OG1
 CL
O3
O2
O
5p8y 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 THR A:34 A:34 98.0 0.7 H -81.0 -42.3 98.0 0.7 0.0 CL
NHE
D1D
HOH
 6.315
6.783
9.870
2.749
 OG1
O
O
O
 CL
O3
O3
O
5p8z 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 THR A:34 A:34 96.0 0.686 H -80.2 -43.8 96.0 0.686 0.0 CL
NHE
D1D
HOH
 6.270
6.808
9.857
2.771
 OG1
O
O
O
 CL
O3
O2
O
5p90 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 THR A:34 A:34 99.0 0.707 H -82.1 -40.2 99.0 0.707 0.0 CL
D1D
NHE
HOH
 6.224
9.921
6.800
2.648
 OG1
O
O
O
 CL
O2
O3
O
5p91 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 THR A:34 A:34 98.0 0.7 H -84.2 -39.5 98.0 0.7 0.0 CL
HOH
 6.189
2.860
 OG1
OG1
 CL
O
5p92 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 THR A:34 A:34 96.0 0.686 H -80.8 -43.0 96.0 0.686 0.0 CL
D1D
NHE
HOH
 6.229
9.911
6.954
2.866
 OG1
O
O
OG1
 CL
O2
O3
O
5p93 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 THR A:34 A:34 100.0 0.714 H -84.0 -40.2 100.0 0.714 0.0 CL
HOH
 6.243
2.718
 OG1
O
 CL
O
5p94 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 THR A:34 A:34 99.0 0.707 H -79.6 -40.9 99.0 0.707 0.0 CL
HOH
 6.206
2.921
 OG1
O
 CL
O
5p9n 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 97.0 0.693 H -85.4 -37.2 97.0 0.693 0.0 CL
NHE
D1D
HOH
 6.128
6.739
9.887
2.842
 OG1
O
O
OG1
 CL
O3
O3
O
5p9o 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 97.0 0.693 H -82.7 -42.6 97.0 0.693 0.0 CL
DTD
NHE
NHE
HOH
 6.298
9.724
6.564
6.955
2.770
 OG1
O
O
O
O
 CL
O3
O3
O2
O
5p9p 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 99.0 0.707 H -83.4 -40.7 99.0 0.707 0.0 CL
HOH
 6.302
2.814
 OG1
O
 CL
O
5p9q 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 96.0 0.686 H -77.9 -43.7 96.0 0.686 0.0 CL
D1D
HOH
 6.255
9.736
3.085
 OG1
O
O
 CL
O2
O
5p9r 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 99.0 0.707 H -83.8 -42.3 99.0 0.707 0.0 HOH
 4.069
 CA
 O
THR B:34 B:34 94.0 0.671 H -82.3 -37.7 NA NA NA
5p9s 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 92.0 0.657 H -75.3 -38.9 92.0 0.657 0.0 HOH
 5.924
 OG1
 O
5p9t 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 97.0 0.693 H -83.8 -41.0 97.0 0.693 0.0 CL
D1D
NHE
HOH
 6.321
9.703
6.723
2.797
 OG1
O
O
O
 CL
O2
O3
O
5p9u 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 51.0 0.364 H -73.2 -45.7 51.0 0.364 0.0 HOH
 4.137
 OG1
 O
5p9v 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 94.0 0.671 H -86.7 -41.6 94.0 0.671 0.0 CL
D1D
CXS
HOH
 6.153
9.479
9.203
2.706
 OG1
O
O
O
 CL
O2
C8
O
5p9x 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 101.0 0.721 H -85.1 -36.3 101.0 0.721 0.0 NHE
HOH
 6.780
2.821
 O
O
 O3
O
5p9y 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 96.0 0.686 H -86.0 -38.4 96.0 0.686 0.0 CL
D1D
NHE
HOH
 6.275
9.812
6.764
2.689
 OG1
O
O
O
 CL
O3
O3
O
5p9z 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 95.0 0.679 H -82.0 -38.2 95.0 0.679 0.0 CL
D1D
HOH
 6.177
9.789
3.045
 OG1
O
O
 CL
O2
O
5pa0 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 94.0 0.671 H -87.1 -37.3 94.0 0.671 0.0 CL
CXS
CXS
SO4
HOH
 6.082
8.840
8.431
5.431
2.623
 HG1
HA
C
O
O
 CL
H92
H72
O3
O
5pa2 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 99.0 0.707 H -82.8 -40.8 99.0 0.707 0.0 CL
D1D
HOH
 6.312
9.631
2.812
 OG1
O
O
 CL
O2
O
5pa3 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 95.0 0.679 H -87.3 -40.8 95.0 0.679 0.0 CL
D1D
HOH
 6.110
9.505
2.664
 OG1
O
O
 CL
O2
O
5pa4 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 87.0 0.621 H -86.4 -43.1 87.0 0.621 0.0 HOH
 6.274
 OG1
 O
5pa5 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 96.0 0.686 H -77.9 -43.7 96.0 0.686 0.0 CL
D1D
HOH
 6.255
9.736
3.085
 OG1
O
O
 CL
O2
O
5pa6 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 98.0 0.7 H -81.8 -42.2 98.0 0.7 0.0 CL
NHE
HOH
 6.717
6.540
3.584
 OG1
O
O
 CL
O3
O
5pa7 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 THR A:34 A:34 97.0 0.693 H -105.5 -26.4 97.0 0.693 0.0 HOH
 8.820
 OG1
 O
THR B:34 B:34 81.0 0.579 H -79.3 -51.3 NA NA NA
5k09 1 P22734 82.03 7e-135 X-RAY
 2016-09-07 THR A:33 A:34 108.0 0.771 H -72.5 -38.6 108.0 0.771 0.0
THR B:33 B:34 115.0 0.821 H -79.5 -28.4 NA NA NA
THR C:33 C:34 114.0 0.814 H -72.2 -33.4 NA NA NA
THR D:33 D:34 113.0 0.807 H -71.1 -25.9 NA NA NA
THR E:33 E:34 123.0 0.879 T -70.0 -5.5 NA NA NA
THR F:33 F:34 117.0 0.836 H -75.0 -34.5 NA NA NA
THR G:33 G:34 108.0 0.771 H -71.5 -41.0 NA NA NA
THR H:33 H:34 110.0 0.786 H -62.7 -39.6 NA NA NA
THR I:33 I:34 108.0 0.771 H -76.5 -29.8 NA NA NA
THR J:33 J:34 107.0 0.764 H -81.9 -31.0 NA NA NA
THR K:33 K:34 109.0 0.779 H -81.7 -19.5 NA NA NA
THR L:33 L:34 119.0 0.85 H -67.6 -20.2 NA NA NA
THR M:33 M:34 116.0 0.829 H -63.0 -28.5 NA NA NA
THR N:33 N:34 124.0 0.886 H -71.8 -16.5 NA NA NA
THR O:33 O:34 106.0 0.757 H -64.5 -41.5 NA NA NA
THR P:33 P:34 108.0 0.771 H -85.6 -32.8 NA NA NA
THR Q:33 Q:34 109.0 0.779 H -56.7 -46.9 NA NA NA
THR R:33 R:34 110.0 0.786 H -83.2 -30.2 NA NA NA
THR S:33 S:34 110.0 0.786 H -66.0 -37.3 NA NA NA
THR T:33 T:34 110.0 0.786 H -65.6 -30.9 NA NA NA
THR U:33 U:34 110.0 0.786 H -69.3 -31.6 NA NA NA
THR V:33 V:34 103.0 0.736 H -83.9 -35.2 NA NA NA
THR W:33 W:34 117.0 0.836 H -87.5 -21.7 NA NA NA
THR X:33 X:34 126.0 0.9 H -74.1 -20.7 NA NA NA
5k0b 1 P22734 81.65 8e-135 X-RAY
 2016-09-07 THR A:33 A:34 57.0 0.407 I -125.3 -3.8 57.0 0.407 0.0 HOH
 5.119
 CG2
 O
THR B:33 B:34 48.0 0.343 I -115.5 -12.7 NA NA NA
THR C:33 C:34 36.0 0.257 I -120.6 -12.2 NA NA NA
THR D:33 D:34 46.0 0.329 I -116.8 -16.9 NA NA NA
THR E:33 E:34 90.0 0.643 H -104.3 -23.1 NA NA NA
THR F:33 F:34 54.0 0.386 I -120.5 -14.0 NA NA NA
THR G:33 G:34 55.0 0.393 H -103.9 -24.4 NA NA NA
THR H:33 H:34 47.0 0.336 I -118.7 -11.2 NA NA NA
4p7f 1 O88587 81.19 1e-134 X-RAY
 2014-06-11 SER A:34 A:77 25.0 0.217 H -70.8 -46.8 25.0 0.217 0.0 PO4
PO4
HOH
 9.975
9.208
2.417
 HG
O
HG
 O1
O4
O
5k0f 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 THR A:33 A:34 113.0 0.807 I -102.3 -16.4 113.0 0.807 0.0 HOH
 3.431
 CG2
 O
THR B:33 B:34 57.0 0.407 I -91.0 -28.1 NA NA NA
5k0g 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 THR A:33 A:34 110.0 0.786 H -99.7 -16.9 110.0 0.786 0.0 HOH
 4.123
 CG2
 O
THR B:33 B:34 63.0 0.45 I -94.6 -27.7 NA NA NA
5k0j 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 THR A:33 A:34 70.0 0.5 H -91.6 -20.2 70.0 0.5 0.0 HOH
 3.522
 CG2
 O
THR B:33 B:34 67.0 0.479 I -100.5 -25.9 NA NA NA
5k0n 1 P22734 81.94 4e-134 X-RAY
 2016-09-07 THR A:33 A:34 60.0 0.429 H -88.9 -27.9 60.0 0.429 0.0 HOH
 4.325
 OG1
 O
THR B:33 B:34 64.0 0.457 H -93.7 -39.5 NA NA NA
THR C:33 C:34 79.0 0.564 H -87.8 -37.4 NA NA NA
THR D:33 D:34 102.0 0.729 H -83.1 -35.7 NA NA NA
5k0l 1 P22734 81.94 4e-134 X-RAY
 2016-09-07 THR A:33 A:34 67.0 0.479 H -83.8 -36.1 67.0 0.479 0.0 HOH
 4.227
 CA
 O
THR B:33 B:34 66.0 0.471 H -92.8 -38.5 NA NA NA
THR C:33 C:34 91.0 0.65 H -80.3 -40.1 NA NA NA
THR D:33 D:34 108.0 0.771 H -89.5 -32.3 NA NA NA
5k0c 1 P22734 82.33 5e-134 X-RAY
 2016-09-07 THR A:33 A:34 112.0 0.8 I -95.8 -21.5 112.0 0.8 0.0 HOH
 3.578
 CG2
 O
THR B:33 B:34 60.0 0.429 I -99.2 -26.0 NA NA NA
5k0e 1 P22734 82.33 5e-134 X-RAY
 2016-09-07 THR A:33 A:34 109.0 0.779 H -82.5 -27.0 109.0 0.779 0.0
6aw5 1 ? 81.0 5e-134 X-RAY
 2018-09-12 THR A:34 A:34 36.0 0.257 H -58.6 -47.5 36.0 0.257 0.0 HOH
 3.077
 OG1
 O
6aw6 1 ? 81.0 5e-134 X-RAY
 2018-09-12 THR A:34 A:34 30.0 0.214 H -69.9 -42.0 30.0 0.214 0.0 HOH
 3.018
 OG1
 O
6aw9 1 ? 81.0 5e-134 X-RAY
 2018-09-12 THR A:34 A:34 107.0 0.764 H -105.3 -17.3 107.0 0.764 0.0 HOH
 6.023
 CG2
 O
THR B:34 B:34 57.0 0.407 H -109.4 -20.4 NA NA NA
THR C:34 C:34 86.0 0.614 H -86.0 -34.0 NA NA NA
6aw4 1 ? 80.54 2e-133 X-RAY
 2018-09-12 THR A:34 A:34 29.0 0.207 H -65.3 -42.7 29.0 0.207 0.0 TRS
HOH
 7.751
3.201
 N
OG1
 N
O
6aw7 1 ? 80.54 2e-133 X-RAY
 2018-09-12 THR A:34 A:34 108.0 0.771 H -90.7 -27.0 108.0 0.771 0.0 HOH
 3.961
 CG2
 O
THR B:34 B:34 61.0 0.436 H -103.9 -23.2 NA NA NA
6aw8 1 ? 80.54 2e-133 X-RAY
 2018-09-12 THR A:34 A:34 114.0 0.814 H -101.0 -11.9 114.0 0.814 0.0
THR B:34 B:34 69.0 0.493 H -107.4 -29.2 NA NA NA
THR C:34 C:34 98.0 0.7 H -84.9 -27.8 NA NA NA
5k05 1 P22734 82.24 2e-133 X-RAY
 2016-09-07 THR A:32 A:34 48.0 0.343 H -78.8 -43.2 48.0 0.343 0.0 SO4
HOH
 9.855
8.740
 O
CG2
 O2
O
THR B:32 B:34 82.0 0.586 H -74.7 -35.8 NA NA NA
1h1d 1 P22734 81.11 2e-133 X-RAY
 2003-07-17 THR A:34 A:34 94.0 0.671 H -82.3 -33.4 94.0 0.671 0.0 BIA
HOH
 9.738
4.810
 O
OG1
 C10
O
1jr4 1 P22734 81.11 2e-133 X-RAY
 2002-08-10 THR A:34 A:34 95.0 0.679 H -92.9 -48.6 95.0 0.679 0.0
1vid 1 P22734 81.11 2e-133 X-RAY
 1996-07-11 THR A:34 A:34 95.0 0.679 H -75.4 -39.8 95.0 0.679 0.0 HOH
 3.700
 O
 O
2cl5 1 P22734 81.11 2e-133 X-RAY
 2006-06-28 THR A:34 A:34 96.0 0.686 H -78.6 -41.0 96.0 0.686 0.0 HOH
 2.489
 O
 O
THR B:34 B:34 90.0 0.643 H -84.2 -37.0 NA NA NA
3hvh 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 THR A:34 A:77 98.0 0.7 H -83.7 -40.9 98.0 0.7 0.0 CXS
CL
SO4
HOH
 9.342
6.431
5.027
3.686
 O
OG1
O
OG1
 C2
CL
O4
O
3hvi 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 THR A:34 A:77 94.0 0.671 H -81.1 -39.6 94.0 0.671 0.0 CL
HOH
 6.044
2.733
 OG1
OG1
 CL
O
3hvj 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 THR A:34 A:77 96.0 0.686 H -77.2 -33.7 96.0 0.686 0.0 CL
BTB
HOH
 6.611
3.071
4.267
 OG1
O
O
 CL
C5
O
THR B:34 B:77 83.0 0.593 H -80.2 -37.5 NA NA NA
3hvk 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 THR A:34 A:77 101.0 0.721 H -83.4 -39.7 101.0 0.721 0.0 NHE
HOH
 6.498
3.676
 O
O
 O1
O
3nw9 1 P22734 81.11 2e-133 X-RAY
 2011-03-16 THR A:34 A:34 97.0 0.693 H -86.2 -40.9 97.0 0.693 0.0 CL
NHE
HOH
 6.140
6.993
3.846
 OG1
O
O
 CL
O3
O
3nwb 1 P22734 81.11 2e-133 X-RAY
 2011-08-03 THR A:34 A:34 97.0 0.693 H -86.1 -39.1 97.0 0.693 0.0 NHE
HOH
 6.526
3.195
 O
HA
 O3
O
3s68 1 P22734 81.11 2e-133 X-RAY
 2012-02-01 THR A:34 A:34 94.0 0.671 H -86.3 -36.2 94.0 0.671 0.0 CL
HOH
 5.952
3.424
 OG1
HA
 CL
O
4p7g 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 THR A:34 A:77 33.0 0.236 H -75.4 -48.7 33.0 0.236 0.0
THR B:34 B:77 38.0 0.271 H -66.1 -48.8 NA NA NA
THR C:34 C:77 35.0 0.25 H -56.0 -49.7 NA NA NA
THR D:34 D:77 38.0 0.271 H -65.8 -49.9 NA NA NA
4p7j 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 THR A:34 A:77 30.0 0.214 H -67.4 -40.8 30.0 0.214 0.0 HOH
 3.425
 CG2
 O
4p7k 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 THR A:34 A:77 39.0 0.279 H -64.6 -46.3 39.0 0.279 0.0 HOH
 2.742
 OG1
 O
4pyl 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 THR A:34 A:77 85.0 0.607 H -73.4 -43.6 85.0 0.607 0.0 HOH
 9.107
 OG1
 O
5lqc 1 P22734 81.11 2e-133 X-RAY
 2016-08-31 THR A:34 A:34 54.0 0.386 H -86.4 -27.3 54.0 0.386 0.0 HOH
 6.439
 O
 O
5lqr 1 P22734 81.11 2e-133 X-RAY
 2016-10-05 THR A:34 A:34 99.0 0.707 H -84.0 -37.1 99.0 0.707 0.0 CL
NHE
HOH
 6.474
6.639
2.559
 OG1
O
O
 CL
O1
O
5lqu 1 P22734 81.11 2e-133 X-RAY
 2016-10-05 THR A:34 A:34 101.0 0.721 H -78.3 -35.0 101.0 0.721 0.0 CL
BTB
HOH
 6.555
3.159
2.746
 OG1
O
OG1
 CL
C5
O
THR B:34 B:34 89.0 0.636 H -81.6 -37.2 NA NA NA
5p95 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 THR A:34 A:34 99.0 0.707 H -85.3 -38.4 99.0 0.707 0.0 CL
NHE
HOH
 6.150
7.143
2.706
 OG1
O
O
 CL
O1
O
5p96 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 THR A:34 A:34 99.0 0.707 H -80.9 -42.9 99.0 0.707 0.0 NHE
CL
HOH
 6.827
6.202
2.776
 O
OG1
O
 O1
CL
O
5p97 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 THR A:34 A:34 97.0 0.693 H -85.8 -37.5 97.0 0.693 0.0 CL
NHE
HOH
 6.170
6.829
2.847
 OG1
O
O
 CL
O1
O
5p98 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 THR A:34 A:34 99.0 0.707 H -90.1 -36.8 99.0 0.707 0.0 CL
NHE
HOH
 6.168
7.320
2.729
 OG1
O
O
 CL
O1
O
5p99 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 THR A:34 A:34 100.0 0.714 H -88.7 -34.6 100.0 0.714 0.0 CL
HOH
 6.233
2.725
 OG1
O
 CL
O
5p9a 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 THR A:34 A:34 101.0 0.721 H -89.3 -41.3 101.0 0.721 0.0 HOH
 2.874
 O
 O
5p9b 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 THR A:34 A:34 100.0 0.714 H -93.0 -34.6 100.0 0.714 0.0 NHE
HOH
 7.625
2.740
 O
O
 O1
O
5p9c 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 THR A:34 A:34 99.0 0.707 H -88.5 -38.5 99.0 0.707 0.0 HOH
 2.717
 O
 O
5p9d 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 THR A:34 A:34 102.0 0.729 H -89.5 -39.3 102.0 0.729 0.0 D1D
HOH
 9.983
2.992
 O
O
 O2
O
5p9e 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 THR A:34 A:34 98.0 0.7 H -87.5 -37.2 98.0 0.7 0.0 CL
HOH
 6.165
2.646
 OG1
O
 CL
O
5p9w 1 P22734 81.11 2e-133 X-RAY
 2017-11-22 THR A:34 A:34 98.0 0.7 H -82.8 -43.0 98.0 0.7 0.0 CL
D1D
NHE
HOH
 6.142
9.849
6.815
2.828
 OG1
O
O
O
 CL
O2
O2
O
5pa1 1 P22734 81.11 2e-133 X-RAY
 2017-11-22 THR A:34 A:34 96.0 0.686 H -83.2 -39.9 96.0 0.686 0.0 CL
D1D
NHE
HOH
 6.152
9.587
7.289
2.653
 OG1
O
O
O
 CL
O2
O2
O
2zlb 1 P22734 81.11 3e-133 X-RAY
 2008-10-07 THR A:36 A:34 51.0 0.364 H -64.6 -38.3 51.0 0.364 0.0 HOH
 4.925
 CG2
 O
2zth 1 P22734 81.11 3e-133 X-RAY
 2009-01-13 THR A:36 A:34 65.0 0.464 T -68.8 -48.9 65.0 0.464 0.0 HOH
 4.939
 N
 O
2zvj 1 P22734 81.11 3e-133 X-RAY
 2009-01-06 THR A:36 A:34 97.0 0.693 I -84.2 -41.0 97.0 0.693 0.0 HOH
 4.478
 OG1
 O
3a7d 1 P22734 81.11 3e-133 X-RAY
 2010-09-15 THR A:36 A:34 99.0 0.707 H -81.6 -34.1 99.0 0.707 0.0 SO4
HOH
 4.670
4.063
 OG1
O
 O3
O
6gy1 1 P22734 81.11 3e-133 X-RAY
 2018-10-10 THR A:36 A:34 95.0 0.679 H -81.0 -30.0 95.0 0.679 0.0 HOH
 6.106
 OG1
 O
6lfe 1 P22734 81.11 3e-133 X-RAY
 2020-03-04 THR A:36 A:34 95.0 0.679 H -81.3 -44.4 95.0 0.679 0.0 IPA
HOH
 3.249
3.050
 O
OG1
 C3
O
5k01 1 P22734 81.78 1e-132 X-RAY
 2016-09-07 THR A:32 A:34 89.0 0.636 H -64.8 -39.5 89.0 0.636 0.0 HOH
 3.147
 HA
 O
5k03 1 P22734 81.78 1e-132 X-RAY
 2016-09-07 THR A:32 A:34 88.0 0.629 H -58.3 -51.7 88.0 0.629 0.0 HOH
 2.436
 OG1
 O
4p58 1 O88587 81.6 2e-131 X-RAY
 2014-06-25 SER A:31 A:77 63.0 0.548 -79.6 101.7 63.0 0.548 0.0 HOH
 5.201
 N
 O
5fhq 1 P22734 81.22 9e-131 X-RAY
 2016-02-03 THR A:32 A:34 47.0 0.336 H -74.7 -39.0 47.0 0.336 0.0 HOH
 2.709
 O
 O
5lqa 1 P22734 81.22 9e-131 X-RAY
 2016-10-05 THR A:32 A:34 96.0 0.686 H -84.6 -38.7 96.0 0.686 0.0 NHE
CL
HOH
 6.594
6.332
2.740
 O
OG1
O
 O1
CL
O
5fhr 1 P22734 80.75 2e-129 X-RAY
 2016-02-03 THR A:32 A:77 9.0 0.064 H -115.6 -15.2 4.0 0.029 0.035 B:P22734:0.036
 HOH
 2.814
 OG1
 O
THR B:32 B:77 7.0 0.05 H -112.1 -14.9 3.0 0.021 0.029 A:P22734:0.029
 HOH
 2.862
 OG1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21964-f1 1 P21964 100.0 0.0 GLU A:84 A:84 141.0 0.742 H -74.5 -42.3