Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 19950331 . C A CCDS13770.1:NM_000754.3:c.282gaC>gaA_NP_000745.1:p.94D>E Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4pyi 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 ASP A:44 A:94 63.0 0.42 H -77.3 -32.3 63.0 0.42 0.0 HOH
 7.182
 C
 O
4pyj 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 ASP A:44 A:94 70.0 0.467 -165.0 154.5 70.0 0.467 0.0 HOH
 5.830
 CB
 O
4pyk 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 ASP A:44 A:94 48.0 0.32 T 53.9 34.8 48.0 0.32 0.0
5lsa 1 P21964 100.0 3e-165 X-RAY
 2016-09-07 ASP A:44 A:94 69.0 0.46 H -74.1 -44.1 69.0 0.46 0.0 CL
SAM
HOH
 3.408
8.670
2.569
 N
N
OD2
 CL
O
O
6i3c 1 P21964 99.1 4e-164 X-RAY
 2019-09-18 ASP A:55 A:44 74.0 0.493 H -74.3 -41.3 74.0 0.493 0.0 HOH
 2.045
 OD1
 O
6i3d 1 P21964 99.1 4e-164 X-RAY
 2019-09-18 ASP A:55 A:44 67.0 0.447 H -78.1 -37.2 67.0 0.447 0.0 SFG
HOH
 8.751
3.554
 N
N
 O
O
ASP B:55 B:44 62.0 0.413 H -75.1 -39.6 NA NA NA
4xuc 1 P21964 99.54 1e-161 X-RAY
 2015-04-15 ASP A:47 A:94 52.0 0.347 H -73.3 -41.4 52.0 0.347 0.0 SAM
HOH
 8.636
2.967
 N
N
 O
O
4xud 1 P21964 99.54 1e-161 X-RAY
 2015-04-15 ASP A:47 A:94 50.0 0.333 H -80.2 -36.0 50.0 0.333 0.0 SAM
HOH
 8.667
3.056
 N
OD1
 O
O
4xue 1 P21964 100.0 1e-159 X-RAY
 2015-04-15 ASP A:44 B:94 71.0 0.473 H -79.9 -36.6 71.0 0.473 0.0 SAM
HOH
 8.606
3.544
 N
N
 O
O
ASP B:44 A:94 61.0 0.407 H -78.0 -36.6 NA NA NA
3a7e 1 P21964 100.0 1e-159 X-RAY
 2010-09-15 ASP A:46 A:44 57.0 0.38 H -74.3 -34.3 57.0 0.38 0.0 SAM
HOH
 8.825
7.344
 N
OD1
 O
O
3bwm 1 P21964 100.0 2e-159 X-RAY
 2008-06-03 ASP A:43 A:44 72.0 0.48 H -72.7 -40.8 72.0 0.48 0.0 SAM
HOH
 8.658
3.531
 N
N
 O
O
3bwy 1 Q6ICE6 99.53 5e-159 X-RAY
 2008-06-03 ASP A:43 A:44 69.0 0.46 H -74.2 -44.6 69.0 0.46 0.0 SAM
HOH
 8.656
2.264
 N
OD1
 O
O
3nwe 1 P22734 82.03 6e-135 X-RAY
 2011-08-03 ASP A:44 A:44 68.0 0.453 H -78.8 -31.1 68.0 0.453 0.0 CL
CL
662
HOH
 9.072
2.664
9.675
2.527
 N
H
N
OD1
 CL
CL
HO20
O
3oe4 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ASP A:44 A:44 62.0 0.413 H -69.8 -35.5 62.0 0.413 0.0 HOH
 2.572
 OD1
 O
3oe5 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ASP A:44 A:44 61.0 0.407 H -73.4 -33.9 61.0 0.407 0.0 HOH
 2.581
 OD1
 O
3ozr 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ASP A:44 A:44 64.0 0.427 H -76.0 -36.6 64.0 0.427 0.0 CL
HOH
 9.012
2.502
 N
OD2
 CL
O
3ozs 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ASP A:44 A:44 64.0 0.427 H -76.5 -34.1 64.0 0.427 0.0 HOH
 2.752
 OD2
 O
3ozt 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ASP A:44 A:44 57.0 0.38 H -76.2 -30.3 57.0 0.38 0.0 HOH
 2.634
 OD1
 O
3r6t 1 P22734 82.03 6e-135 X-RAY
 2012-02-01 ASP A:44 A:87 64.0 0.427 H -76.0 -34.8 64.0 0.427 0.0 CL
CL
HOH
 9.047
3.379
2.263
 N
N
OD1
 CL
CL
O
3u81 1 P22734 82.03 6e-135 X-RAY
 2012-02-01 ASP A:44 A:44 77.0 0.513 H -69.8 -37.1 77.0 0.513 0.0 SAH
HOH
 8.665
2.536
 N
OD2
 O
O
4pym 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ASP A:44 A:87 77.0 0.513 H -66.9 -39.2 77.0 0.513 0.0 SO4
HOH
 9.529
2.484
 N
HB2
 O1
O
4pyn 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ASP A:44 A:87 74.0 0.493 H -69.0 -35.2 74.0 0.493 0.0 SAH
HOH
 8.495
2.250
 N
OD2
 OXT
O
4pyo 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ASP A:44 A:87 121.0 0.807 H -84.4 -19.8 121.0 0.807 0.0 HOH
 2.852
 OD2
 O
ASP B:44 B:87 71.0 0.473 H -73.6 -31.7 NA NA NA
4pyq 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ASP A:44 A:87 60.0 0.4 I -79.5 -36.3 35.0 0.233 0.167 B:P22734:0.167
 HOH
 2.348
 O
 O
ASP B:44 B:87 69.0 0.46 I -78.0 -32.1 41.0 0.273 0.187 A:P22734:0.187
 CL
HOH
 3.828
2.448
 OD1
O
 CL
O
5lqj 1 P22734 82.03 6e-135 X-RAY
 2016-09-28 ASP A:44 A:44 74.0 0.493 H -112.1 -16.8 74.0 0.493 0.0 HOH
 4.793
 OD2
 O
ASP B:44 B:44 71.0 0.473 H -76.9 -24.4 NA NA NA
ASP C:44 C:44 78.0 0.52 H -96.9 -17.1 NA NA NA
ASP D:44 D:44 77.0 0.513 H -79.3 -44.1 NA NA NA
5lqk 1 P22734 82.03 6e-135 X-RAY
 2016-08-31 ASP A:44 A:44 71.0 0.473 H -70.1 -43.6 71.0 0.473 0.0 CL
CL
HOH
 8.991
3.554
3.292
 N
N
N
 CL
CL
O
5lqn 1 P22734 82.03 6e-135 X-RAY
 2016-10-05 ASP A:44 A:44 84.0 0.56 S -77.1 -33.7 84.0 0.56 0.0 HOH
 4.358
 OD1
 O
5lr6 1 P22734 82.03 6e-135 X-RAY
 2016-08-31 ASP A:44 A:44 65.0 0.433 S -89.0 -24.2 65.0 0.433 0.0 HOH
 4.064
 CG
 O
ASP B:44 B:44 70.0 0.467 S -110.8 -6.7 NA NA NA
ASP C:44 C:44 70.0 0.467 H -72.1 -24.5 NA NA NA
ASP D:44 D:44 71.0 0.473 H -75.1 -32.8 NA NA NA
5p8w 1 P22734 82.03 6e-135 X-RAY
 2016-09-07 ASP A:44 A:44 63.0 0.42 H -71.9 -29.6 63.0 0.42 0.0 DTT
HOH
 9.003
2.894
 N
N
 O2
O
ASP B:44 B:44 123.0 0.82 H -64.3 -60.6 86.0 0.573 0.247 C:P22734:0.247
 FMT
HOH
 8.727
2.924
 C
O
 O2
O
ASP C:44 C:44 50.0 0.333 H -73.8 -47.6 50.0 0.333 0.0 DTT
HOH
 8.955
5.479
 N
OD2
 O2
O
5p8x 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ASP A:44 A:44 62.0 0.413 H -75.6 -35.0 62.0 0.413 0.0 CL
CL
HOH
 9.094
3.427
2.661
 N
N
OD1
 CL
CL
O
5p8y 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ASP A:44 A:44 61.0 0.407 H -72.8 -32.8 61.0 0.407 0.0 CL
CL
HOH
 8.961
3.550
2.762
 N
N
OD1
 CL
CL
O
5p8z 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ASP A:44 A:44 63.0 0.42 H -75.9 -32.3 63.0 0.42 0.0 CL
CL
HOH
 9.035
3.493
2.782
 N
N
OD1
 CL
CL
O
5p90 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ASP A:44 A:44 62.0 0.413 H -75.3 -35.3 62.0 0.413 0.0 CL
CL
HOH
 9.063
3.477
2.703
 N
N
OD1
 CL
CL
O
5p91 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ASP A:44 A:44 65.0 0.433 H -75.2 -36.7 65.0 0.433 0.0 CL
CL
HOH
 9.033
3.469
2.613
 N
N
OD2
 CL
CL
O
5p92 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ASP A:44 A:44 63.0 0.42 H -74.0 -34.4 63.0 0.42 0.0 CL
CL
HOH
 9.054
3.457
2.740
 N
N
OD1
 CL
CL
O
5p93 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ASP A:44 A:44 63.0 0.42 H -76.6 -35.2 63.0 0.42 0.0 CL
CL
HOH
 9.021
3.538
2.685
 N
N
OD1
 CL
CL
O
5p94 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ASP A:44 A:44 65.0 0.433 H -74.5 -35.2 65.0 0.433 0.0 CL
CL
HOH
 9.091
3.410
2.182
 N
N
OD1
 CL
CL
O
5p9n 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 61.0 0.407 H -76.7 -35.3 61.0 0.407 0.0 CL
CL
HOH
 9.120
3.412
2.598
 N
N
OD1
 CL
CL
O
5p9o 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 64.0 0.427 H -78.8 -35.9 64.0 0.427 0.0 SAH
CL
HOH
 8.789
3.374
2.275
 N
N
OD1
 OXT
CL
O
5p9p 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 64.0 0.427 H -80.0 -37.0 64.0 0.427 0.0 CL
SAH
HOH
 3.352
8.799
2.358
 N
N
OD1
 CL
OXT
O
5p9q 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 62.0 0.413 H -77.8 -35.1 62.0 0.413 0.0 CL
SAH
HOH
 3.338
8.811
2.682
 N
N
OD2
 CL
OXT
O
5p9r 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 67.0 0.447 H -74.1 -40.3 67.0 0.447 0.0 SAH
HOH
 8.784
3.390
 N
N
 O
O
ASP B:44 B:44 73.0 0.487 H -75.3 -46.1 NA NA NA
5p9s 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 67.0 0.447 H -80.6 -38.7 67.0 0.447 0.0 SAH
HOH
 8.710
3.256
 N
N
 O
O
5p9t 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 64.0 0.427 H -79.2 -38.6 64.0 0.427 0.0 CL
SAH
HOH
 3.451
8.732
2.731
 N
N
OD2
 CL
OXT
O
5p9u 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 63.0 0.42 H -79.2 -34.5 63.0 0.42 0.0 SAH
HOH
 8.668
2.816
 N
OD2
 OXT
O
5p9v 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 56.0 0.373 H -77.1 -36.2 56.0 0.373 0.0 CL
SAH
HOH
 3.388
8.758
2.458
 N
N
OD1
 CL
OXT
O
5p9x 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 68.0 0.453 H -72.0 -38.0 68.0 0.453 0.0 CL
CL
HOH
 9.108
3.396
2.467
 N
N
OD2
 CL
CL
O
5p9y 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 64.0 0.427 H -75.6 -33.6 64.0 0.427 0.0 CL
CL
HOH
 9.062
3.480
2.544
 N
N
OD1
 CL
CL
O
5p9z 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 63.0 0.42 H -74.0 -36.4 63.0 0.42 0.0 CL
SAH
HOH
 3.489
8.823
2.747
 N
N
OD1
 CL
OXT
O
5pa0 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 59.0 0.393 H -79.2 -35.7 59.0 0.393 0.0 SAH
7JR
CL
HOH
 8.777
9.694
2.709
2.112
 N
N
H
H
 OXT
H91
CL
O
5pa2 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 64.0 0.427 H -77.4 -37.7 64.0 0.427 0.0 CL
SAH
HOH
 3.428
8.783
2.703
 N
N
OD1
 CL
OXT
O
5pa3 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 61.0 0.407 H -79.1 -37.1 61.0 0.407 0.0 SAH
CL
HOH
 8.817
3.406
2.469
 N
N
OD2
 OXT
CL
O
5pa4 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 67.0 0.447 H -71.5 -38.8 67.0 0.447 0.0 SAH
HOH
 8.824
2.589
 N
OD2
 OXT
O
5pa5 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 62.0 0.413 H -77.8 -35.1 62.0 0.413 0.0 CL
SAH
HOH
 3.338
8.811
2.682
 N
N
OD2
 CL
OXT
O
5pa6 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 65.0 0.433 H -76.2 -35.4 65.0 0.433 0.0 SAH
CL
HOH
 8.772
3.483
2.859
 N
N
N
 OXT
CL
O
5pa7 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:44 A:44 74.0 0.493 H -72.2 -42.8 74.0 0.493 0.0 SAH
7JX
HOH
 8.737
9.982
3.915
 N
N
N
 O
O12
O
ASP B:44 B:44 132.0 0.88 H -74.6 -30.7 NA NA NA
5k09 1 P22734 82.03 7e-135 X-RAY
 2016-09-07 ASP A:43 A:44 88.0 0.587 H -75.7 -46.4 88.0 0.587 0.0 HOH
 5.346
 N
 O
ASP B:43 B:44 93.0 0.62 H -66.5 -42.2 NA NA NA
ASP C:43 C:44 78.0 0.52 H -86.7 -25.6 NA NA NA
ASP D:43 D:44 89.0 0.593 H -76.8 -48.3 NA NA NA
ASP E:43 E:44 90.0 0.6 H -66.8 -37.7 NA NA NA
ASP F:43 F:44 95.0 0.633 H -73.6 -47.0 NA NA NA
ASP G:43 G:44 79.0 0.527 S -102.8 -32.1 NA NA NA
ASP H:43 H:44 89.0 0.593 S -94.1 -38.8 NA NA NA
ASP I:43 I:44 85.0 0.567 H -83.6 -41.1 NA NA NA
ASP J:43 J:44 84.0 0.56 H -69.5 -42.8 NA NA NA
ASP K:43 K:44 90.0 0.6 H -99.9 -38.3 NA NA NA
ASP L:43 L:44 88.0 0.587 H -82.9 -42.8 NA NA NA
ASP M:43 M:44 73.0 0.487 H -91.7 -39.8 NA NA NA
ASP N:43 N:44 97.0 0.647 H -71.2 -44.2 NA NA NA
ASP O:43 O:44 90.0 0.6 H -73.9 -37.4 NA NA NA
ASP P:43 P:44 102.0 0.68 H -55.4 -57.2 NA NA NA
ASP Q:43 Q:44 84.0 0.56 H -88.3 -33.1 NA NA NA
ASP R:43 R:44 103.0 0.687 H -62.6 -44.0 NA NA NA
ASP S:43 S:44 86.0 0.573 H -80.9 -33.6 NA NA NA
ASP T:43 T:44 81.0 0.54 H -92.9 -32.5 NA NA NA
ASP U:43 U:44 96.0 0.64 H -74.6 -45.7 NA NA NA
ASP V:43 V:44 97.0 0.647 H -78.1 -44.2 NA NA NA
ASP W:43 W:44 97.0 0.647 H -75.4 -45.3 NA NA NA
ASP X:43 X:44 90.0 0.6 H -85.7 -43.4 NA NA NA
5k0b 1 P22734 81.65 8e-135 X-RAY
 2016-09-07 ASP A:43 A:44 65.0 0.433 H -71.8 -33.3 65.0 0.433 0.0 HOH
 3.183
 OD1
 O
ASP B:43 B:44 64.0 0.427 H -70.3 -36.3 NA NA NA
ASP C:43 C:44 69.0 0.46 H -75.1 -32.5 NA NA NA
ASP D:43 D:44 76.0 0.507 H -71.3 -36.1 NA NA NA
ASP E:43 E:44 79.0 0.527 H -73.5 -25.8 NA NA NA
ASP F:43 F:44 60.0 0.4 H -74.8 -30.1 NA NA NA
ASP G:43 G:44 60.0 0.4 H -74.9 -30.7 NA NA NA
ASP H:43 H:44 74.0 0.493 H -72.8 -30.6 NA NA NA
4p7f 1 O88587 81.19 1e-134 X-RAY
 2014-06-11 ASP A:44 A:87 63.0 0.42 I -79.2 -33.9 63.0 0.42 0.0 PO4
HOH
 3.713
2.744
 OD1
O
 O4
O
5k0f 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 ASP A:43 A:44 60.0 0.4 H -69.7 -31.5 60.0 0.4 0.0 HOH
 2.999
 N
 O
ASP B:43 B:44 65.0 0.433 H -68.0 -35.6 NA NA NA
5k0g 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 ASP A:43 A:44 63.0 0.42 H -68.4 -33.2 63.0 0.42 0.0 HOH
 2.850
 N
 O
ASP B:43 B:44 64.0 0.427 H -67.1 -33.9 NA NA NA
5k0j 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 ASP A:43 A:44 50.0 0.333 H -74.4 -29.4 50.0 0.333 0.0 HOH
 2.902
 N
 O
ASP B:43 B:44 62.0 0.413 H -74.2 -28.4 NA NA NA
5k0n 1 P22734 81.94 4e-134 X-RAY
 2016-09-07 ASP A:43 A:44 68.0 0.453 H -72.1 -31.0 68.0 0.453 0.0 HOH
 2.983
 N
 O
ASP B:43 B:44 67.0 0.447 S -79.7 -29.8 NA NA NA
ASP C:43 C:44 61.0 0.407 H -73.0 -30.0 NA NA NA
ASP D:43 D:44 54.0 0.36 H -66.8 -32.3 NA NA NA
5k0l 1 P22734 81.94 4e-134 X-RAY
 2016-09-07 ASP A:43 A:44 67.0 0.447 H -77.9 -30.7 67.0 0.447 0.0 HOH
 2.851
 N
 O
ASP B:43 B:44 74.0 0.493 H -80.2 -31.2 NA NA NA
ASP C:43 C:44 64.0 0.427 H -71.4 -27.9 NA NA NA
ASP D:43 D:44 56.0 0.373 H -68.2 -35.2 NA NA NA
5k0c 1 P22734 82.33 5e-134 X-RAY
 2016-09-07 ASP A:43 A:44 61.0 0.407 H -70.8 -31.6 61.0 0.407 0.0 HOH
 2.482
 OD2
 O
ASP B:43 B:44 67.0 0.447 H -64.8 -35.2 NA NA NA
5k0e 1 P22734 82.33 5e-134 X-RAY
 2016-09-07 ASP A:43 A:44 89.0 0.593 H -81.9 -28.2 89.0 0.593 0.0
6aw5 1 ? 81.0 5e-134 X-RAY
 2018-09-12 ASP A:44 A:44 113.0 0.753 I -82.3 -35.1 113.0 0.753 0.0 HOH
 3.156
 N
 O
6aw6 1 ? 81.0 5e-134 X-RAY
 2018-09-12 ASP A:44 A:44 117.0 0.78 I -77.9 -36.2 117.0 0.78 0.0 HOH
 2.827
 O
 O
6aw9 1 ? 81.0 5e-134 X-RAY
 2018-09-12 ASP A:44 A:44 61.0 0.407 H -73.8 -37.7 61.0 0.407 0.0 SAH
HOH
 8.954
4.086
 N
N
 O
O
ASP B:44 B:44 69.0 0.46 H -82.2 -38.6 NA NA NA
ASP C:44 C:44 78.0 0.52 T -86.1 -32.4 NA NA NA
6aw4 1 ? 80.54 2e-133 X-RAY
 2018-09-12 ASP A:44 A:44 72.0 0.48 I -75.7 -37.2 72.0 0.48 0.0 HOH
 2.769
 O
 O
6aw7 1 ? 80.54 2e-133 X-RAY
 2018-09-12 ASP A:44 A:44 68.0 0.453 H -71.4 -42.9 68.0 0.453 0.0 SAH
HOH
 8.773
2.508
 N
OD1
 OXT
O
ASP B:44 B:44 69.0 0.46 H -84.0 -37.9 NA NA NA
6aw8 1 ? 80.54 2e-133 X-RAY
 2018-09-12 ASP A:44 A:44 72.0 0.48 H -77.7 -38.2 72.0 0.48 0.0 SAH
HOH
 8.711
2.398
 N
OD1
 OXT
O
ASP B:44 B:44 63.0 0.42 H -84.0 -33.9 NA NA NA
ASP C:44 C:44 62.0 0.413 H -83.4 -36.6 NA NA NA
5k05 1 P22734 82.24 2e-133 X-RAY
 2016-09-07 ASP A:42 A:44 65.0 0.433 H -97.0 -19.4 65.0 0.433 0.0 HOH
 2.644
 OD1
 O
ASP B:42 B:44 64.0 0.427 H -62.8 -37.7 NA NA NA
1h1d 1 P22734 81.11 2e-133 X-RAY
 2003-07-17 ASP A:44 A:44 66.0 0.44 H -79.2 -36.5 66.0 0.44 0.0 SAM
HOH
 8.736
2.934
 N
N
 O
O
1jr4 1 P22734 81.11 2e-133 X-RAY
 2002-08-10 ASP A:44 A:44 70.0 0.467 H -83.2 -36.9 70.0 0.467 0.0 HOH
 6.737
 O
 O
1vid 1 P22734 81.11 2e-133 X-RAY
 1996-07-11 ASP A:44 A:44 72.0 0.48 H -77.1 -36.4 72.0 0.48 0.0 SAM
HOH
 8.590
2.723
 N
N
 O
O
2cl5 1 P22734 81.11 2e-133 X-RAY
 2006-06-28 ASP A:44 A:44 60.0 0.4 H -70.4 -36.3 60.0 0.4 0.0 SAM
HOH
 8.645
2.684
 N
OD1
 O
O
ASP B:44 B:44 56.0 0.373 H -73.0 -36.8 NA NA NA
3hvh 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 ASP A:44 A:87 64.0 0.427 H -73.3 -32.4 64.0 0.427 0.0 CL
HOH
 3.482
2.646
 N
OD1
 CL
O
3hvi 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 ASP A:44 A:87 64.0 0.427 H -77.1 -34.8 64.0 0.427 0.0 CL
HOH
 3.345
2.164
 N
OD1
 CL
O
3hvj 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 ASP A:44 A:87 81.0 0.54 H -73.7 -42.3 81.0 0.54 0.0 CL
HOH
 3.210
2.714
 N
OD2
 CL
O
ASP B:44 B:87 65.0 0.433 H -70.6 -36.7 NA NA NA
3hvk 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 ASP A:44 A:87 63.0 0.42 H -76.8 -33.8 63.0 0.42 0.0 CL
CL
HOH
 9.089
3.357
2.472
 N
N
OD1
 CL
CL
O
3nw9 1 P22734 81.11 2e-133 X-RAY
 2011-03-16 ASP A:44 A:44 61.0 0.407 H -71.9 -36.1 61.0 0.407 0.0 CL
CL
HOH
 9.039
3.391
2.453
 N
N
OD2
 CL
CL
O
3nwb 1 P22734 81.11 2e-133 X-RAY
 2011-08-03 ASP A:44 A:44 67.0 0.447 H -74.4 -36.2 67.0 0.447 0.0 CL
CL
659
HOH
 9.066
2.758
9.735
2.432
 N
H
N
OD2
 CL
CL
HO22
O
3s68 1 P22734 81.11 2e-133 X-RAY
 2012-02-01 ASP A:44 A:44 60.0 0.4 H -78.2 -33.9 60.0 0.4 0.0 CL
TCW
SAM
HOH
 2.620
9.608
8.774
2.544
 H
N
N
OD1
 CL
HO7
O
O
4p7g 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 ASP A:44 A:87 80.0 0.533 T -115.2 -18.8 80.0 0.533 0.0
ASP B:44 B:87 79.0 0.527 T -123.2 -16.9 NA NA NA
ASP C:44 C:87 66.0 0.44 T -104.8 -56.6 NA NA NA
ASP D:44 D:87 79.0 0.527 H -107.1 -22.3 NA NA NA
4p7j 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 ASP A:44 A:87 85.0 0.567 I -76.8 -39.2 85.0 0.567 0.0 HOH
 2.348
 OD1
 O
4p7k 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 ASP A:44 A:87 75.0 0.5 H -68.2 -32.9 75.0 0.5 0.0 SFG
HOH
 8.587
2.538
 N
HB2
 O
O
4pyl 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 ASP A:44 A:87 73.0 0.487 H -76.0 -39.4 73.0 0.487 0.0 SFG
TCW
HOH
 8.607
9.970
3.753
 N
N
N
 OXT
O7
O
5lqc 1 P22734 81.11 2e-133 X-RAY
 2016-08-31 ASP A:44 A:44 73.0 0.487 H -74.9 -34.0 73.0 0.487 0.0 HOH
 3.868
 N
 O
5lqr 1 P22734 81.11 2e-133 X-RAY
 2016-10-05 ASP A:44 A:44 66.0 0.44 H -71.7 -32.6 66.0 0.44 0.0 CL
CL
HOH
 9.032
3.433
2.297
 N
N
OD1
 CL
CL
O
5lqu 1 P22734 81.11 2e-133 X-RAY
 2016-10-05 ASP A:44 A:44 83.0 0.553 H -71.1 -46.7 83.0 0.553 0.0 CL
HOH
 3.236
2.708
 N
OD2
 CL
O
ASP B:44 B:44 66.0 0.44 H -74.9 -31.5 NA NA NA
5p95 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:44 A:44 65.0 0.433 H -77.9 -33.7 65.0 0.433 0.0 CL
CL
HOH
 9.105
3.422
1.965
 N
N
OD1
 CL
CL
O
5p96 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:44 A:44 63.0 0.42 H -75.5 -32.9 63.0 0.42 0.0 CL
CL
HOH
 9.079
3.440
2.305
 N
N
OD1
 CL
CL
O
5p97 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:44 A:44 67.0 0.447 H -71.3 -38.3 67.0 0.447 0.0 CL
CL
HOH
 3.366
9.075
2.416
 N
N
OD1
 CL
CL
O
5p98 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:44 A:44 64.0 0.427 H -76.8 -36.5 64.0 0.427 0.0 CL
CL
HOH
 9.045
3.442
2.114
 N
N
OD1
 CL
CL
O
5p99 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:44 A:44 68.0 0.453 H -74.0 -36.3 68.0 0.453 0.0 CL
CL
HOH
 9.121
3.423
2.243
 N
N
OD1
 CL
CL
O
5p9a 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:44 A:44 68.0 0.453 H -71.9 -39.4 68.0 0.453 0.0 K
HOH
 9.134
2.655
 N
OD2
 K
O
5p9b 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:44 A:44 68.0 0.453 H -72.8 -37.1 68.0 0.453 0.0 CL
CL
HOH
 9.052
3.389
2.362
 N
N
OD1
 CL
CL
O
5p9c 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:44 A:44 63.0 0.42 H -71.0 -37.2 63.0 0.42 0.0 K
HOH
 9.069
2.724
 N
OD1
 K
O
5p9d 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:44 A:44 70.0 0.467 H -75.6 -36.4 70.0 0.467 0.0 K
HOH
 9.110
2.455
 N
OD1
 K
O
5p9e 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:44 A:44 66.0 0.44 H -76.5 -38.0 66.0 0.44 0.0 CL
CL
HOH
 3.440
9.093
2.661
 N
N
OD2
 CL
CL
O
5p9w 1 P22734 81.11 2e-133 X-RAY
 2017-11-22 ASP A:44 A:44 64.0 0.427 H -73.3 -34.1 64.0 0.427 0.0 CL
CL
HOH
 3.407
9.132
2.243
 N
N
OD1
 CL
CL
O
5pa1 1 P22734 81.11 2e-133 X-RAY
 2017-11-22 ASP A:44 A:44 63.0 0.42 H -81.9 -33.4 63.0 0.42 0.0 CL
SAH
HOH
 3.367
8.797
2.288
 N
N
OD1
 CL
O
O
2zlb 1 P22734 81.11 3e-133 X-RAY
 2008-10-07 ASP A:46 A:44 77.0 0.513 H -45.5 -51.7 77.0 0.513 0.0 HOH
 3.324
 OD1
 O
2zth 1 P22734 81.11 3e-133 X-RAY
 2009-01-13 ASP A:46 A:44 73.0 0.487 S -84.6 -9.5 73.0 0.487 0.0 SAM
HOH
 9.256
3.090
 N
N
 O
O
2zvj 1 P22734 81.11 3e-133 X-RAY
 2009-01-06 ASP A:46 A:44 62.0 0.413 H -75.0 -42.4 62.0 0.413 0.0 SAM
KOM
HOH
 8.655
9.813
4.064
 N
N
N
 O
O10
O
3a7d 1 P22734 81.11 3e-133 X-RAY
 2010-09-15 ASP A:46 A:44 56.0 0.373 H -76.1 -34.7 56.0 0.373 0.0 SO4
SO4
HOH
 8.493
3.124
4.184
 N
N
N
 O1
O4
O
6gy1 1 P22734 81.11 3e-133 X-RAY
 2018-10-10 ASP A:46 A:44 62.0 0.413 H -81.5 -37.9 62.0 0.413 0.0 SAH
HOH
 8.733
3.528
 N
N
 O
O
6lfe 1 P22734 81.11 3e-133 X-RAY
 2020-03-04 ASP A:46 A:44 61.0 0.407 H -77.9 -36.4 61.0 0.407 0.0 SAM
HOH
 8.774
2.663
 N
OD2
 OXT
O
5k01 1 P22734 81.78 1e-132 X-RAY
 2016-09-07 ASP A:42 A:44 61.0 0.407 H -70.0 -35.0 61.0 0.407 0.0 HOH
 2.001
 H
 O
5k03 1 P22734 81.78 1e-132 X-RAY
 2016-09-07 ASP A:42 A:44 60.0 0.4 H -70.2 -35.3 60.0 0.4 0.0 HOH
 2.483
 OD2
 O
4p58 1 O88587 81.6 2e-131 X-RAY
 2014-06-25 ASP A:41 A:87 83.0 0.553 H -81.8 -31.8 83.0 0.553 0.0 HOH
 2.673
 OD2
 O
5fhq 1 P22734 81.22 9e-131 X-RAY
 2016-02-03 ASP A:42 A:44 47.0 0.313 H -74.3 -37.6 47.0 0.313 0.0 SAM
DNC
HOH
 8.561
9.374
2.863
 N
N
OD1
 OXT
HO1
O
5lqa 1 P22734 81.22 9e-131 X-RAY
 2016-10-05 ASP A:42 A:44 64.0 0.427 H -73.6 -36.0 64.0 0.427 0.0 CL
CL
HOH
 9.057
3.399
2.143
 N
N
OD1
 CL
CL
O
5fhr 1 P22734 80.75 2e-129 X-RAY
 2016-02-03 ASP A:42 A:87 64.0 0.427 H -69.7 -39.8 64.0 0.427 0.0 DNC
SAM
HOH
 9.866
8.621
2.511
 N
N
OD2
 O1
OXT
O
ASP B:42 B:87 61.0 0.407 H -70.6 -41.8 61.0 0.407 0.0 DNC
SAM
HOH
 9.861
8.585
2.578
 N
N
OD1
 O1
OXT
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21964-f1 1 P21964 100.0 0.0 ASP A:94 A:94 48.0 0.32 H -69.1 -42.0