Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 19951172 . C A CCDS13770.1:NM_000754.3:c.373Cgc>Agc_NP_000745.1:p.125R>S Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4pyi 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 ARG A:75 A:125 7.0 0.031 H -56.0 -50.2 7.0 0.031 0.0 HOH
 5.409
 HH22
 O
4pyj 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 ARG A:75 A:125 16.0 0.071 H -55.7 -46.1 16.0 0.071 0.0 CL
HOH
 8.237
6.624
 N
NH1
 CL
O
4pyk 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 ARG A:75 A:125 41.0 0.182 H -51.9 -49.0 41.0 0.182 0.0 CL
HOH
 8.166
7.154
 CB
N
 CL
O
5lsa 1 P21964 100.0 3e-165 X-RAY
 2016-09-07 ARG A:75 A:125 8.0 0.036 H -60.6 -44.8 8.0 0.036 0.0 CL
SAM
HOH
 7.798
7.413
2.998
 NH1
CB
NH2
 CL
O
O
6i3c 1 P21964 99.1 4e-164 X-RAY
 2019-09-18 ARG A:86 A:75 10.0 0.044 H -63.0 -45.4 10.0 0.044 0.0 SAM
HOH
 7.513
2.984
 CB
NH2
 OXT
O
6i3d 1 P21964 99.1 4e-164 X-RAY
 2019-09-18 ARG A:86 A:75 5.0 0.022 H -59.7 -46.7 5.0 0.022 0.0 SFG
HOH
 7.416
4.250
 CB
NH2
 OXT
O
ARG B:86 B:75 6.0 0.027 H -59.2 -44.1 NA NA NA
4xuc 1 P21964 99.54 1e-161 X-RAY
 2015-04-15 ARG A:78 A:125 5.0 0.022 H -56.9 -46.9 5.0 0.022 0.0 SAM
HOH
 7.232
3.044
 CB
NH2
 OXT
O
4xud 1 P21964 99.54 1e-161 X-RAY
 2015-04-15 ARG A:78 A:125 3.0 0.013 H -61.6 -44.8 3.0 0.013 0.0 SAM
HOH
 7.311
4.640
 CB
NH1
 O
O
4xue 1 P21964 100.0 1e-159 X-RAY
 2015-04-15 ARG A:75 B:125 8.0 0.036 H -55.9 -46.7 8.0 0.036 0.0 SAM
HOH
 7.340
4.300
 CB
NH2
 OXT
O
ARG B:75 A:125 5.0 0.022 H -62.5 -47.1 NA NA NA
3a7e 1 P21964 100.0 1e-159 X-RAY
 2010-09-15 ARG A:77 A:75 6.0 0.027 H -60.1 -40.5 6.0 0.027 0.0 SAM
HOH
 7.449
4.931
 CB
NH1
 OXT
O
3bwm 1 P21964 100.0 2e-159 X-RAY
 2008-06-03 ARG A:74 A:75 4.0 0.018 H -55.2 -43.5 4.0 0.018 0.0 SAM
HOH
 7.202
4.375
 CB
NH1
 O
O
3bwy 1 Q6ICE6 99.53 5e-159 X-RAY
 2008-06-03 ARG A:74 A:75 5.0 0.022 H -60.6 -45.9 5.0 0.022 0.0 SAM
HOH
 7.340
2.573
 CB
NH2
 O
O
3nwe 1 P22734 82.03 6e-135 X-RAY
 2011-08-03 ARG A:75 A:75 6.0 0.027 H -56.7 -47.2 6.0 0.027 0.0 CL
CL
HOH
 6.949
7.432
1.977
 HB2
HH22
HH22
 CL
CL
O
3oe4 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ARG A:75 A:75 3.0 0.013 H -58.5 -47.3 3.0 0.013 0.0 HOH
 2.904
 NH1
 O
3oe5 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ARG A:75 A:75 3.0 0.013 H -57.7 -46.8 3.0 0.013 0.0 HOH
 2.929
 NH1
 O
3ozr 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ARG A:75 A:75 1.0 0.004 H -57.7 -45.4 1.0 0.004 0.0 CL
HOH
 7.404
4.871
 CB
NH1
 CL
O
3ozs 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ARG A:75 A:75 3.0 0.013 H -55.5 -47.2 3.0 0.013 0.0 HOH
 4.467
 NH1
 O
3ozt 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ARG A:75 A:75 4.0 0.018 H -54.9 -50.2 4.0 0.018 0.0 HOH
 2.917
 NH1
 O
3r6t 1 P22734 82.03 6e-135 X-RAY
 2012-02-01 ARG A:75 A:118 7.0 0.031 H -54.9 -51.8 7.0 0.031 0.0 HOH
 3.123
 O
 O
3u81 1 P22734 82.03 6e-135 X-RAY
 2012-02-01 ARG A:75 A:75 9.0 0.04 H -56.3 -48.1 9.0 0.04 0.0 SAH
HOH
 6.730
2.057
 HB3
HH12
 O
O
4pym 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ARG A:75 A:118 10.0 0.044 H -57.4 -46.7 10.0 0.044 0.0 SO4
HOH
 6.595
2.148
 H
HH12
 O1
O
4pyn 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ARG A:75 A:118 8.0 0.036 H -57.8 -47.5 8.0 0.036 0.0 SAH
HOH
 6.737
2.146
 HB3
HH12
 OXT
O
4pyo 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ARG A:75 A:118 19.0 0.084 H -62.3 -49.7 19.0 0.084 0.0 SAH
HOH
 7.527
6.842
 CB
N
 O
O
ARG B:75 B:118 4.0 0.018 H -57.3 -49.6 NA NA NA
4pyq 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ARG A:75 A:118 16.0 0.071 H -55.4 -43.6 16.0 0.071 0.0 SO4
HOH
 6.502
1.939
 HB2
HH22
 O4
O
ARG B:75 B:118 22.0 0.098 H -59.3 -44.2 22.0 0.098 0.0 CL
SO4
HOH
 2.812
6.501
3.168
 HH22
HB2
HH21
 CL
O2
O
5lqj 1 P22734 82.03 6e-135 X-RAY
 2016-09-28 ARG A:75 A:75 6.0 0.027 H -59.8 -38.8 6.0 0.027 0.0 HOH
 6.202
 NH2
 O
ARG B:75 B:75 6.0 0.027 H -51.0 -44.5 NA NA NA
ARG C:75 C:75 6.0 0.027 H -58.6 -43.9 NA NA NA
ARG D:75 D:75 7.0 0.031 H -53.7 -44.4 NA NA NA
5lqk 1 P22734 82.03 6e-135 X-RAY
 2016-08-31 ARG A:75 A:75 3.0 0.013 H -63.1 -40.0 3.0 0.013 0.0 CL
CL
HOH
 7.203
7.990
7.020
 CB
NH2
NH2
 CL
CL
O
5lqn 1 P22734 82.03 6e-135 X-RAY
 2016-10-05 ARG A:75 A:75 8.0 0.036 H -53.0 -49.6 8.0 0.036 0.0 HOH
 4.913
 NH1
 O
5lr6 1 P22734 82.03 6e-135 X-RAY
 2016-08-31 ARG A:75 A:75 3.0 0.013 H -75.3 -30.2 3.0 0.013 0.0 HOH
 3.921
 NH1
 O
ARG B:75 B:75 2.0 0.009 H -61.1 -38.2 NA NA NA
ARG C:75 C:75 2.0 0.009 H -41.9 -53.2 NA NA NA
ARG D:75 D:75 2.0 0.009 H -58.2 -51.3 NA NA NA
5p8w 1 P22734 82.03 6e-135 X-RAY
 2016-09-07 ARG A:75 A:75 6.0 0.027 H -60.7 -45.6 6.0 0.027 0.0 DTT
HOH
 9.723
4.101
 N
NH2
 S1
O
ARG B:75 B:75 22.0 0.098 H -62.9 -38.4 22.0 0.098 0.0 DTT
HOH
 9.708
3.100
 N
NH2
 S1
O
ARG C:75 C:75 15.0 0.067 H -62.8 -45.3 15.0 0.067 0.0 DTT
HOH
 9.654
6.699
 CB
N
 S1
O
5p8x 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ARG A:75 A:75 4.0 0.018 H -61.0 -45.4 4.0 0.018 0.0 HOH
 3.040
 O
 O
5p8y 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ARG A:75 A:75 4.0 0.018 H -58.2 -47.8 4.0 0.018 0.0 CL
CL
HOH
 7.495
8.004
2.989
 CB
NH2
O
 CL
CL
O
5p8z 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ARG A:75 A:75 4.0 0.018 H -57.7 -47.4 4.0 0.018 0.0 CL
CL
HOH
 7.520
7.991
3.021
 CB
NH2
NH1
 CL
CL
O
5p90 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ARG A:75 A:75 5.0 0.022 H -60.9 -45.3 5.0 0.022 0.0 HOH
 3.024
 O
 O
5p91 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ARG A:75 A:75 4.0 0.018 H -59.4 -46.3 4.0 0.018 0.0 HOH
 3.038
 O
 O
5p92 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ARG A:75 A:75 3.0 0.013 H -53.7 -49.3 3.0 0.013 0.0 CL
CL
HOH
 7.563
8.003
3.007
 CB
NH2
NH1
 CL
CL
O
5p93 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ARG A:75 A:75 4.0 0.018 H -58.6 -48.4 4.0 0.018 0.0 HOH
 3.129
 O
 O
5p94 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ARG A:75 A:75 3.0 0.013 H -58.4 -48.6 3.0 0.013 0.0 HOH
 3.015
 O
 O
5p9n 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 4.0 0.018 H -60.9 -44.5 4.0 0.018 0.0 CL
CL
HOH
 7.475
7.892
2.940
 CB
NH2
NH1
 CL
CL
O
5p9o 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 3.0 0.013 H -61.9 -42.3 3.0 0.013 0.0 SAH
CL
HOH
 7.446
7.813
2.606
 CB
NH2
NH2
 O
CL
O
5p9p 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 3.0 0.013 H -60.9 -43.9 3.0 0.013 0.0 HOH
 2.973
 O
 O
5p9q 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 4.0 0.018 H -65.3 -43.1 4.0 0.018 0.0 CL
SAH
HOH
 7.747
7.323
3.141
 NH2
CB
O
 CL
O
O
5p9r 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 1.0 0.004 H -59.8 -45.6 1.0 0.004 0.0 SAH
HOH
 7.390
4.571
 CD
NH1
 O
O
ARG B:75 B:75 7.0 0.031 H -57.6 -48.6 NA NA NA
5p9s 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 2.0 0.009 H -55.4 -43.8 2.0 0.009 0.0 SAH
HOH
 7.153
6.360
 CB
NH1
 OXT
O
5p9t 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 4.0 0.018 H -58.9 -44.4 4.0 0.018 0.0 HOH
 3.000
 O
 O
5p9u 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 5.0 0.022 H -58.3 -46.5 5.0 0.022 0.0 SAH
HOH
 7.430
4.347
 CB
NH2
 OXT
O
5p9v 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 4.0 0.018 H -58.4 -47.1 4.0 0.018 0.0 CL
SAH
HOH
 7.772
7.403
2.689
 NH2
CB
NH2
 CL
OXT
O
5p9x 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 5.0 0.022 H -60.5 -46.0 5.0 0.022 0.0 CL
CL
HOH
 7.427
7.896
2.656
 CB
NH2
NH2
 CL
CL
O
5p9y 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 4.0 0.018 H -58.4 -50.4 4.0 0.018 0.0 CL
CL
HOH
 7.540
7.996
3.032
 CB
NH2
NH1
 CL
CL
O
5p9z 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 4.0 0.018 H -57.4 -49.2 4.0 0.018 0.0 CL
SAH
HOH
 7.845
7.360
3.068
 NH2
CB
O
 CL
O
O
5pa0 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 4.0 0.018 H -58.3 -46.8 4.0 0.018 0.0 SAH
CL
HOH
 6.807
7.409
1.928
 H
HH22
HH22
 O
CL
O
5pa2 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 4.0 0.018 H -57.3 -49.2 4.0 0.018 0.0 CL
SAH
HOH
 7.864
7.340
3.013
 NH2
CB
O
 CL
O
O
5pa3 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 4.0 0.018 H -57.1 -49.1 4.0 0.018 0.0 SAH
CL
HOH
 7.294
7.759
3.126
 CB
NH2
NH1
 O
CL
O
5pa4 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 5.0 0.022 H -58.7 -47.4 5.0 0.022 0.0 SAH
HOH
 7.414
3.361
 CB
NH2
 OXT
O
5pa5 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 4.0 0.018 H -65.3 -43.1 4.0 0.018 0.0 CL
SAH
HOH
 7.747
7.323
3.141
 NH2
CB
O
 CL
O
O
5pa6 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 5.0 0.022 H -53.3 -50.8 5.0 0.022 0.0 HOH
 3.067
 O
 O
5pa7 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:75 A:75 4.0 0.018 H -58.4 -49.4 4.0 0.018 0.0 SAH
HOH
 7.465
6.721
 CB
N
 OXT
O
ARG B:75 B:75 28.0 0.124 H -54.1 -51.6 NA NA NA
5k09 1 P22734 82.03 7e-135 X-RAY
 2016-09-07 ARG A:74 A:75 13.0 0.058 H -58.3 -54.0 13.0 0.058 0.0 HOH
 9.377
 NH2
 O
ARG B:74 B:75 16.0 0.071 H -64.9 -37.7 NA NA NA
ARG C:74 C:75 7.0 0.031 H -58.8 -46.8 NA NA NA
ARG D:74 D:75 16.0 0.071 H -58.8 -40.5 NA NA NA
ARG E:74 E:75 14.0 0.062 H -49.7 -47.8 NA NA NA
ARG F:74 F:75 12.0 0.053 H -47.7 -51.6 NA NA NA
ARG G:74 G:75 12.0 0.053 H -58.8 -31.1 NA NA NA
ARG H:74 H:75 17.0 0.076 H -64.2 -47.6 NA NA NA
ARG I:74 I:75 13.0 0.058 H -53.1 -45.2 NA NA NA
ARG J:74 J:75 15.0 0.067 H -60.0 -41.8 NA NA NA
ARG K:74 K:75 10.0 0.044 H -44.5 -67.7 NA NA NA
ARG L:74 L:75 12.0 0.053 H -77.4 -39.8 NA NA NA
ARG M:74 M:75 8.0 0.036 H -62.7 -45.6 NA NA NA
ARG N:74 N:75 18.0 0.08 H -51.0 -51.6 NA NA NA
ARG O:74 O:75 10.0 0.044 H -68.5 -39.7 NA NA NA
ARG P:74 P:75 13.0 0.058 H -53.2 -44.8 NA NA NA
ARG Q:74 Q:75 13.0 0.058 H -57.1 -42.0 NA NA NA
ARG R:74 R:75 12.0 0.053 H -51.4 -39.0 NA NA NA
ARG S:74 S:75 13.0 0.058 H -58.4 -41.7 NA NA NA
ARG T:74 T:75 10.0 0.044 H -52.4 -50.7 NA NA NA
ARG U:74 U:75 15.0 0.067 H -56.1 -58.4 NA NA NA
ARG V:74 V:75 17.0 0.076 H -47.7 -51.5 NA NA NA
ARG W:74 W:75 19.0 0.084 H -48.9 -54.8 NA NA NA
ARG X:74 X:75 18.0 0.08 H -58.7 -51.5 NA NA NA
5k0b 1 P22734 81.65 8e-135 X-RAY
 2016-09-07 ARG A:74 A:75 4.0 0.018 H -56.2 -52.4 4.0 0.018 0.0 HOH
 4.058
 NH2
 O
ARG B:74 B:75 3.0 0.013 H -57.8 -45.5 NA NA NA
ARG C:74 C:75 2.0 0.009 H -56.7 -45.5 NA NA NA
ARG D:74 D:75 4.0 0.018 H -55.6 -49.4 NA NA NA
ARG E:74 E:75 4.0 0.018 H -56.7 -49.3 NA NA NA
ARG F:74 F:75 5.0 0.022 H -52.1 -46.0 NA NA NA
ARG G:74 G:75 4.0 0.018 H -54.5 -51.6 NA NA NA
ARG H:74 H:75 4.0 0.018 H -53.5 -51.7 NA NA NA
4p7f 1 O88587 81.19 1e-134 X-RAY
 2014-06-11 ARG A:75 A:118 21.0 0.093 H -54.8 -48.1 21.0 0.093 0.0 PO4
PO4
PI
HOH
 1.979
8.406
6.639
2.725
 HH12
O
HB2
HG3
 O1
O2
O4
O
5k0f 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 ARG A:74 A:75 3.0 0.013 H -52.2 -50.5 3.0 0.013 0.0 HOH
 4.170
 NH1
 O
ARG B:74 B:75 4.0 0.018 H -52.5 -51.8 NA NA NA
5k0g 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 ARG A:74 A:75 4.0 0.018 H -52.4 -49.8 4.0 0.018 0.0 HOH
 4.067
 NH1
 O
ARG B:74 B:75 4.0 0.018 H -52.3 -50.4 NA NA NA
5k0j 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 ARG A:74 A:75 2.0 0.009 H -53.2 -47.1 2.0 0.009 0.0 HOH
 4.127
 NH2
 O
ARG B:74 B:75 4.0 0.018 H -50.6 -46.0 NA NA NA
5k0n 1 P22734 81.94 4e-134 X-RAY
 2016-09-07 ARG A:74 A:75 2.0 0.009 H -54.3 -46.8 2.0 0.009 0.0 HOH
 4.316
 NH1
 O
ARG B:74 B:75 3.0 0.013 H -65.1 -42.8 NA NA NA
ARG C:74 C:75 4.0 0.018 H -54.0 -50.7 NA NA NA
ARG D:74 D:75 2.0 0.009 H -54.8 -50.9 NA NA NA
5k0l 1 P22734 81.94 4e-134 X-RAY
 2016-09-07 ARG A:74 A:75 1.0 0.004 H -54.3 -52.7 1.0 0.004 0.0 HOH
 4.071
 NH1
 O
ARG B:74 B:75 2.0 0.009 H -60.9 -44.4 NA NA NA
ARG C:74 C:75 5.0 0.022 H -56.5 -49.1 NA NA NA
ARG D:74 D:75 1.0 0.004 H -50.2 -56.5 NA NA NA
5k0c 1 P22734 82.33 5e-134 X-RAY
 2016-09-07 ARG A:74 A:75 4.0 0.018 H -50.5 -50.4 4.0 0.018 0.0 HOH
 4.203
 NH1
 O
ARG B:74 B:75 3.0 0.013 H -51.9 -48.1 NA NA NA
5k0e 1 P22734 82.33 5e-134 X-RAY
 2016-09-07 ARG A:74 A:75 4.0 0.018 H -60.8 -45.7 4.0 0.018 0.0 CL
HOH
 8.967
6.597
 N
N
 CL
O
6aw5 1 ? 81.0 5e-134 X-RAY
 2018-09-12 ARG A:75 A:75 28.0 0.124 H -54.7 -44.3 28.0 0.124 0.0 CL
HOH
 8.236
3.597
 N
NH1
 CL
O
6aw6 1 ? 81.0 5e-134 X-RAY
 2018-09-12 ARG A:75 A:75 25.0 0.111 H -57.7 -44.1 25.0 0.111 0.0 SO4
HOH
 7.255
2.938
 CB
NH1
 O3
O
6aw9 1 ? 81.0 5e-134 X-RAY
 2018-09-12 ARG A:75 A:75 4.0 0.018 H -57.6 -44.4 4.0 0.018 0.0 SAH
HOH
 6.913
3.955
 CB
NH2
 OXT
O
ARG B:75 B:75 10.0 0.044 H -63.0 -42.1 NA NA NA
ARG C:75 C:75 10.0 0.044 H -56.7 -36.3 NA NA NA
6aw4 1 ? 80.54 2e-133 X-RAY
 2018-09-12 ARG A:75 A:75 19.0 0.084 H -55.2 -45.6 19.0 0.084 0.0 TRS
PO4
HOH
 7.627
7.246
3.675
 CB
CB
NH1
 O1
O3
O
6aw7 1 ? 80.54 2e-133 X-RAY
 2018-09-12 ARG A:75 A:75 3.0 0.013 H -56.9 -48.0 3.0 0.013 0.0 SAH
HOH
 7.496
3.369
 CB
NH1
 O
O
ARG B:75 B:75 4.0 0.018 H -59.7 -49.2 NA NA NA
6aw8 1 ? 80.54 2e-133 X-RAY
 2018-09-12 ARG A:75 A:75 10.0 0.044 H -50.6 -52.3 10.0 0.044 0.0 SAH
HOH
 7.388
3.217
 CB
NH1
 OXT
O
ARG B:75 B:75 4.0 0.018 H -58.0 -46.0 NA NA NA
ARG C:75 C:75 5.0 0.022 H -55.2 -44.8 NA NA NA
5k05 1 P22734 82.24 2e-133 X-RAY
 2016-09-07 ARG A:73 A:75 3.0 0.013 H -59.6 -48.8 3.0 0.013 0.0 HOH
 3.917
 NH2
 O
ARG B:73 B:75 5.0 0.022 H -57.5 -52.3 NA NA NA
1h1d 1 P22734 81.11 2e-133 X-RAY
 2003-07-17 ARG A:75 A:75 5.0 0.022 H -58.9 -48.5 5.0 0.022 0.0 SAM
HOH
 7.112
4.237
 CB
NH2
 O
O
1jr4 1 P22734 81.11 2e-133 X-RAY
 2002-08-10 ARG A:75 A:75 6.0 0.027 H -54.0 -45.1 6.0 0.027 0.0 HOH
 6.371
 NH1
 O
1vid 1 P22734 81.11 2e-133 X-RAY
 1996-07-11 ARG A:75 A:75 4.0 0.018 H -57.7 -45.7 4.0 0.018 0.0 SAM
HOH
 7.306
3.080
 CB
NH1
 O
O
2cl5 1 P22734 81.11 2e-133 X-RAY
 2006-06-28 ARG A:75 A:75 2.0 0.009 H -58.8 -48.1 2.0 0.009 0.0 SAM
HOH
 7.137
2.899
 CD
NH2
 O
O
ARG B:75 B:75 3.0 0.013 H -56.8 -48.4 NA NA NA
3hvh 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 ARG A:75 A:118 5.0 0.022 H -57.7 -47.9 5.0 0.022 0.0 HOH
 3.153
 O
 O
3hvi 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 ARG A:75 A:118 4.0 0.018 H -61.9 -46.5 4.0 0.018 0.0 CL
HOH
 7.681
2.617
 NH2
NH2
 CL
O
3hvj 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 ARG A:75 A:118 1.0 0.004 H -68.1 -42.5 1.0 0.004 0.0 CL
HOH
 7.933
2.636
 NH2
NH2
 CL
O
ARG B:75 B:118 4.0 0.018 H -59.3 -45.2 NA NA NA
3hvk 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 ARG A:75 A:118 4.0 0.018 H -56.4 -50.3 4.0 0.018 0.0 CL
CL
HOH
 7.195
7.840
2.673
 CG
NH2
NH2
 CL
CL
O
3nw9 1 P22734 81.11 2e-133 X-RAY
 2011-03-16 ARG A:75 A:75 4.0 0.018 H -57.7 -50.5 4.0 0.018 0.0 CL
CL
HOH
 7.403
7.826
2.779
 CB
NH2
NH2
 CL
CL
O
3nwb 1 P22734 81.11 2e-133 X-RAY
 2011-08-03 ARG A:75 A:75 8.0 0.036 H -61.6 -45.3 8.0 0.036 0.0 HOH
 7.766
 O
 O
3s68 1 P22734 81.11 2e-133 X-RAY
 2012-02-01 ARG A:75 A:75 4.0 0.018 H -57.5 -47.2 4.0 0.018 0.0 CL
SAM
HOH
 7.411
6.707
1.983
 HH22
HB3
HH12
 CL
O
O
4p7g 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 ARG A:75 A:118 17.0 0.076 H -53.0 -44.9 17.0 0.076 0.0 PO4
HOH
 7.566
9.503
 CB
O
 O1
O
ARG B:75 B:118 17.0 0.076 H -53.0 -43.8 NA NA NA
ARG C:75 C:118 18.0 0.08 H -52.1 -44.0 NA NA NA
ARG D:75 D:118 19.0 0.084 H -52.3 -43.8 NA NA NA
4p7j 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 ARG A:75 A:118 17.0 0.076 H -56.0 -47.2 17.0 0.076 0.0 SO4
HOH
 7.257
2.911
 CB
NH1
 O3
O
4p7k 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 ARG A:75 A:118 10.0 0.044 H -57.7 -48.6 10.0 0.044 0.0 HOH
 6.108
 H
 O
4pyl 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 ARG A:75 A:118 4.0 0.018 H -56.2 -50.8 4.0 0.018 0.0 SFG
HOH
 7.056
4.515
 CB
NH1
 O
O
5lqc 1 P22734 81.11 2e-133 X-RAY
 2016-08-31 ARG A:75 A:75 4.0 0.018 H -59.1 -44.7 4.0 0.018 0.0 HOH
 4.758
 NH1
 O
5lqr 1 P22734 81.11 2e-133 X-RAY
 2016-10-05 ARG A:75 A:75 6.0 0.027 H -58.0 -46.9 6.0 0.027 0.0 CL
CL
HOH
 7.384
7.909
2.623
 CG
NH2
NH2
 CL
CL
O
5lqu 1 P22734 81.11 2e-133 X-RAY
 2016-10-05 ARG A:75 A:75 1.0 0.004 H -60.8 -45.7 1.0 0.004 0.0 CL
HOH
 7.818
2.659
 NH2
NH2
 CL
O
ARG B:75 B:75 4.0 0.018 H -59.9 -46.6 NA NA NA
5p95 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:75 A:75 4.0 0.018 H -57.3 -48.5 4.0 0.018 0.0 HOH
 2.985
 O
 O
5p96 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:75 A:75 3.0 0.013 H -59.2 -47.8 3.0 0.013 0.0 CL
CL
HOH
 7.519
7.924
2.661
 CB
NH2
NH2
 CL
CL
O
5p97 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:75 A:75 4.0 0.018 H -58.7 -49.1 4.0 0.018 0.0 HOH
 3.139
 O
 O
5p98 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:75 A:75 4.0 0.018 H -56.7 -49.9 4.0 0.018 0.0 HOH
 3.063
 O
 O
5p99 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:75 A:75 4.0 0.018 H -57.2 -49.0 4.0 0.018 0.0 CL
CL
HOH
 7.548
7.962
2.548
 CB
NH2
NH2
 CL
CL
O
5p9a 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:75 A:75 5.0 0.022 H -59.0 -44.7 5.0 0.022 0.0 K
HOH
 7.503
3.052
 CB
O
 K
O
5p9b 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:75 A:75 3.0 0.013 H -57.1 -49.0 3.0 0.013 0.0 HOH
 2.961
 O
 O
5p9c 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:75 A:75 3.0 0.013 H -55.2 -48.6 3.0 0.013 0.0 K
HOH
 7.400
3.572
 CB
NH2
 K
O
5p9d 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:75 A:75 7.0 0.031 H -57.1 -49.3 7.0 0.031 0.0 HOH
 2.958
 O
 O
5p9e 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:75 A:75 6.0 0.027 H -58.8 -47.5 6.0 0.027 0.0 CL
CL
HOH
 7.826
7.359
2.975
 NH2
CB
NH1
 CL
CL
O
5p9w 1 P22734 81.11 2e-133 X-RAY
 2017-11-22 ARG A:75 A:75 4.0 0.018 H -58.8 -47.7 4.0 0.018 0.0 HOH
 3.069
 O
 O
5pa1 1 P22734 81.11 2e-133 X-RAY
 2017-11-22 ARG A:75 A:75 3.0 0.013 H -62.0 -42.5 3.0 0.013 0.0 CL
SAH
HOH
 7.739
7.450
2.701
 NH2
CB
NH2
 CL
OXT
O
2zlb 1 P22734 81.11 3e-133 X-RAY
 2008-10-07 ARG A:77 A:75 13.0 0.058 H -54.5 -49.3 13.0 0.058 0.0 SO4
HOH
 7.100
3.114
 CB
O
 O3
O
2zth 1 P22734 81.11 3e-133 X-RAY
 2009-01-13 ARG A:77 A:75 2.0 0.009 H -57.0 -55.7 2.0 0.009 0.0 SAM
HOH
 7.114
6.716
 CB
N
 O
O
2zvj 1 P22734 81.11 3e-133 X-RAY
 2009-01-06 ARG A:77 A:75 4.0 0.018 H -53.7 -46.7 4.0 0.018 0.0 SAM
HOH
 7.181
4.572
 CB
NH1
 O
O
3a7d 1 P22734 81.11 3e-133 X-RAY
 2010-09-15 ARG A:77 A:75 4.0 0.018 H -54.6 -45.5 4.0 0.018 0.0 SO4
SO4
HOH
 6.366
7.428
6.992
 CB
NH1
N
 O3
O3
O
6gy1 1 P22734 81.11 3e-133 X-RAY
 2018-10-10 ARG A:77 A:75 2.0 0.009 H -61.5 -46.4 2.0 0.009 0.0 SAH
HOH
 7.403
6.177
 CB
NH1
 O
O
6lfe 1 P22734 81.11 3e-133 X-RAY
 2020-03-04 ARG A:77 A:75 4.0 0.018 H -55.5 -48.8 4.0 0.018 0.0 SAM
HOH
 7.383
3.038
 CB
NH1
 OXT
O
5k01 1 P22734 81.78 1e-132 X-RAY
 2016-09-07 ARG A:73 A:75 2.0 0.009 H -56.8 -48.3 2.0 0.009 0.0 HOH
 2.539
 HH22
 O
5k03 1 P22734 81.78 1e-132 X-RAY
 2016-09-07 ARG A:73 A:75 0.0 0.0 H -56.3 -48.9 0.0 0.0 0.0 HOH
 3.024
 NH2
 O
4p58 1 O88587 81.6 2e-131 X-RAY
 2014-06-25 ARG A:72 A:118 10.0 0.044 H -55.4 -48.8 10.0 0.044 0.0 HOH
 4.315
 NH1
 O
5fhq 1 P22734 81.22 9e-131 X-RAY
 2016-02-03 ARG A:73 A:75 4.0 0.018 H -61.1 -46.4 4.0 0.018 0.0 SAM
HOH
 6.727
2.124
 HB3
HH22
 OXT
O
5lqa 1 P22734 81.22 9e-131 X-RAY
 2016-10-05 ARG A:73 A:75 4.0 0.018 H -54.6 -50.9 4.0 0.018 0.0 CL
CL
HOH
 7.328
7.897
2.663
 CG
NH2
NH2
 CL
CL
O
5fhr 1 P22734 80.75 2e-129 X-RAY
 2016-02-03 ARG A:73 A:118 4.0 0.018 H -55.0 -49.5 4.0 0.018 0.0 SAM
HOH
 6.905
2.775
 CD
NH2
 OXT
O
ARG B:73 B:118 4.0 0.018 H -55.8 -49.3 4.0 0.018 0.0 SAM
HOH
 6.890
2.862
 CD
O
 OXT
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21964-f1 1 P21964 100.0 0.0 ARG A:125 A:125 13.0 0.058 H -58.7 -51.5