Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 19951220 . A C CCDS13770.1:NM_000754.3:c.421Atc>Ctc_NP_000745.1:p.141I>L Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4pyi 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 ILE A:91 A:141 116.0 0.663 S -79.4 -26.5 116.0 0.663 0.0 HOH
 2.748
 HB
 O
4pyj 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 ILE A:91 A:141 114.0 0.651 S -75.1 -27.8 114.0 0.651 0.0 HOH
 2.816
 O
 O
4pyk 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 ILE A:91 A:141 112.0 0.64 S -84.9 -18.1 112.0 0.64 0.0 HOH
 3.191
 N
 O
5lsa 1 P21964 100.0 3e-165 X-RAY
 2016-09-07 ILE A:91 A:141 72.0 0.411 S -75.1 -24.2 72.0 0.411 0.0 SAM
HOH
 3.190
2.736
 N
O
 N3
O
6i3c 1 P21964 99.1 4e-164 X-RAY
 2019-09-18 ILE A:102 A:91 72.0 0.411 S -75.6 -28.0 72.0 0.411 0.0 SAM
HOH
 3.271
2.827
 N
O
 N3
O
6i3d 1 P21964 99.1 4e-164 X-RAY
 2019-09-18 ILE A:102 A:91 67.0 0.383 S -81.8 -26.8 67.0 0.383 0.0 DNC
SFG
HOH
 9.923
3.247
2.773
 CG2
N
O
 O3
N3
O
ILE B:102 B:91 68.0 0.389 S -82.1 -25.4 NA NA NA
4xuc 1 P21964 99.54 1e-161 X-RAY
 2015-04-15 ILE A:94 A:141 71.0 0.406 S -79.7 -29.5 71.0 0.406 0.0 SAM
HOH
 3.245
2.706
 N
O
 N3
O
4xud 1 P21964 99.54 1e-161 X-RAY
 2015-04-15 ILE A:94 A:141 72.0 0.411 S -72.1 -35.4 72.0 0.411 0.0 SAM
HOH
 3.181
2.697
 N
O
 N3
O
4xue 1 P21964 100.0 1e-159 X-RAY
 2015-04-15 ILE A:91 B:141 70.0 0.4 S -76.5 -34.8 70.0 0.4 0.0 SAM
HOH
 3.263
2.685
 N
O
 N3
O
ILE B:91 A:141 65.0 0.371 S -76.5 -32.4 NA NA NA
3a7e 1 P21964 100.0 1e-159 X-RAY
 2010-09-15 ILE A:93 A:91 58.0 0.331 -69.1 -34.8 58.0 0.331 0.0 SAM
HOH
 3.247
8.213
 N
CD1
 N3
O
3bwm 1 P21964 100.0 2e-159 X-RAY
 2008-06-03 ILE A:90 A:91 73.0 0.417 S -81.5 -26.5 73.0 0.417 0.0 SAM
HOH
 3.252
3.612
 N
CG2
 N3
O
3bwy 1 Q6ICE6 99.53 5e-159 X-RAY
 2008-06-03 ILE A:90 A:91 67.0 0.383 S -77.3 -26.9 67.0 0.383 0.0 SAM
HOH
 3.221
3.760
 N
CG2
 N3
O
3nwe 1 P22734 82.03 6e-135 X-RAY
 2011-08-03 ILE A:91 A:91 97.0 0.554 -74.0 -29.4 97.0 0.554 0.0 662
NHE
HOH
 2.233
8.394
2.725
 HG22
O
O
 HO11
H5'2
O
3oe4 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ILE A:91 A:91 79.0 0.451 S -79.0 -29.4 79.0 0.451 0.0 610
HOH
 3.080
2.595
 N
O
 N33
O
3oe5 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ILE A:91 A:91 75.0 0.429 S -79.4 -25.3 75.0 0.429 0.0 611
HOH
 3.459
3.606
 CG2
O
 C11
O
3ozr 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ILE A:91 A:91 68.0 0.389 S -72.5 -29.1 68.0 0.389 0.0 OZR
HOH
 4.227
2.926
 CG2
N
 O8
O
3ozs 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ILE A:91 A:91 80.0 0.457 S -79.4 -27.0 80.0 0.457 0.0 OZS
HOH
 3.525
2.691
 CG2
O
 C11
O
3ozt 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ILE A:91 A:91 73.0 0.417 S -82.7 -22.8 73.0 0.417 0.0 OZZ
HOH
 3.369
3.738
 CG2
O
 O9
O
3r6t 1 P22734 82.03 6e-135 X-RAY
 2012-02-01 ILE A:91 A:134 71.0 0.406 S -75.4 -31.0 71.0 0.406 0.0 CL
LU1
HOH
 3.668
3.037
2.811
 CD1
N
O
 CL
N33
O
3u81 1 P22734 82.03 6e-135 X-RAY
 2012-02-01 ILE A:91 A:91 73.0 0.417 S -76.7 -25.9 73.0 0.417 0.0 SAH
HOH
 2.473
3.183
 H
HG23
 N3
O
4pym 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ILE A:91 A:134 111.0 0.634 S -77.0 -31.5 111.0 0.634 0.0 HOH
 2.264
 H
 O
4pyn 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ILE A:91 A:134 73.0 0.417 S -75.5 -26.1 73.0 0.417 0.0 SAH
HOH
 2.475
2.738
 H
O
 N3
O
4pyo 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ILE A:91 A:134 74.0 0.423 S -72.0 -20.1 74.0 0.423 0.0 SAH
HOH
 3.174
2.919
 N
O
 N3
O
ILE B:91 B:134 81.0 0.463 S -84.3 -28.7 NA NA NA
4pyq 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ILE A:91 A:134 93.0 0.531 S -72.9 -35.2 93.0 0.531 0.0 2X1
ACT
HOH
 2.509
4.529
2.648
 HD13
H
H
 C14
CH3
O
ILE B:91 B:134 91.0 0.52 S -76.2 -36.3 91.0 0.52 0.0 2X1
ACT
HOH
 2.859
5.032
2.619
 HD13
H
H
 C14
CH3
O
5lqj 1 P22734 82.03 6e-135 X-RAY
 2016-09-28 ILE A:91 A:91 108.0 0.617 S -84.0 -37.0 108.0 0.617 0.0
ILE B:91 B:91 67.0 0.383 S -73.1 -34.3 NA NA NA
ILE C:91 C:91 111.0 0.634 S -85.8 -29.9 NA NA NA
ILE D:91 D:91 72.0 0.411 S -74.3 -31.2 NA NA NA
5lqk 1 P22734 82.03 6e-135 X-RAY
 2016-08-31 ILE A:91 A:91 99.0 0.566 S -76.0 -21.4 99.0 0.566 0.0 72M
NHE
HOH
 3.010
7.163
3.932
 N
CG2
CG2
 N3
C4'
O
5lqn 1 P22734 82.03 6e-135 X-RAY
 2016-10-05 ILE A:91 A:91 86.0 0.491 S -77.2 -27.3 86.0 0.491 0.0 72O
HOH
 3.301
2.496
 CD1
O
 O13
O
5lr6 1 P22734 82.03 6e-135 X-RAY
 2016-08-31 ILE A:91 A:91 77.0 0.44 S -85.5 -19.8 77.0 0.44 0.0 731
NHE
CL
HOH
 2.945
7.317
4.944
3.129
 N
CD1
CD1
O
 N5
C3'
CL
O
ILE B:91 B:91 80.0 0.457 S -85.2 -25.9 NA NA NA
ILE C:91 C:91 80.0 0.457 S -91.6 -16.4 NA NA NA
ILE D:91 D:91 83.0 0.474 S -85.9 -20.0 NA NA NA
5p8w 1 P22734 82.03 6e-135 X-RAY
 2016-09-07 ILE A:91 A:91 80.0 0.457 S -85.0 -24.6 80.0 0.457 0.0 O01
HOH
 3.192
2.694
 N
O
 N9
O
ILE B:91 B:91 73.0 0.417 S -85.8 -24.8 73.0 0.417 0.0 O01
HOH
 3.042
2.930
 N
O
 N9
O
ILE C:91 C:91 113.0 0.646 S -83.0 -28.0 42.0 0.24 0.406 A:P22734:0.291
B:P22734:0.211
 O01
HOH
 3.187
2.674
 N
O
 N9
O
5p8x 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ILE A:91 A:91 72.0 0.411 S -78.9 -29.1 72.0 0.411 0.0 75Z
HOH
 3.360
2.934
 N
O
 C28
O
5p8y 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ILE A:91 A:91 76.0 0.434 S -81.5 -26.2 76.0 0.434 0.0 763
NHE
HOH
 3.454
7.446
2.824
 CG2
CD1
O
 N24
C4'
O
5p8z 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ILE A:91 A:91 75.0 0.429 S -87.4 -23.7 75.0 0.429 0.0 766
HOH
 3.542
2.786
 CG2
O
 C9
O
5p90 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ILE A:91 A:91 78.0 0.446 S -76.5 -26.3 78.0 0.446 0.0 769
NHE
HOH
 3.440
7.695
2.778
 CG2
CD1
O
 N24
C3'
O
5p91 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ILE A:91 A:91 68.0 0.389 S -78.7 -30.1 68.0 0.389 0.0 NHE
76B
HOH
 9.488
3.252
2.883
 C
CG2
O
 C5'
C13
O
5p92 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ILE A:91 A:91 81.0 0.463 S -79.2 -26.7 81.0 0.463 0.0 76G
HOH
 3.473
2.781
 N
O
 C14
O
5p93 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ILE A:91 A:91 66.0 0.377 S -77.2 -34.7 66.0 0.377 0.0 NHE
76S
HOH
 9.356
3.367
2.840
 O
N
O
 C5'
N21
O
5p94 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ILE A:91 A:91 78.0 0.446 S -77.5 -27.9 78.0 0.446 0.0 NHE
76T
HOH
 9.381
3.401
2.884
 C
CG2
O
 C5'
C21
O
5p9n 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 77.0 0.44 S -77.2 -27.3 77.0 0.44 0.0 7JE
8JE
HOH
 3.633
3.596
2.838
 N
CG2
O
 C15
C11
O
5p9o 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 77.0 0.44 S -78.1 -26.0 77.0 0.44 0.0 SAH
HOH
 3.153
2.816
 N
O
 N3
O
5p9p 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 72.0 0.411 S -78.6 -28.2 72.0 0.411 0.0 SAH
NHE
7JG
D1D
HOH
 3.168
9.595
9.987
9.519
2.800
 N
N
CG2
C
O
 N3
C6'
N18
C1
O
5p9q 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 77.0 0.44 S -75.0 -29.4 77.0 0.44 0.0 SAH
7JH
ACT
HOH
 3.209
9.819
4.193
2.787
 N
CG2
CD1
O
 N3
N9
O
O
5p9r 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 73.0 0.417 S -79.0 -24.0 73.0 0.417 0.0 SAH
HOH
 3.240
3.748
 N
CG2
 N3
O
ILE B:91 B:91 73.0 0.417 S -76.0 -27.8 NA NA NA
5p9s 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 74.0 0.423 S -85.2 -23.9 74.0 0.423 0.0 SAH
7JK
HOH
 3.172
9.747
2.714
 N
CG2
O
 N3
N10
O
5p9t 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 72.0 0.411 S -78.6 -28.0 72.0 0.411 0.0 7JD
SAH
HOH
 9.885
3.201
2.761
 CG2
N
O
 N17
N3
O
5p9u 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 72.0 0.411 S -79.3 -25.4 72.0 0.411 0.0 SAH
7JL
HOH
 3.136
9.925
2.722
 N
CG2
O
 N3
N11
O
5p9v 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 75.0 0.429 S -78.5 -24.2 75.0 0.429 0.0 SAH
HOH
 3.170
2.747
 N
O
 N3
O
5p9x 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 75.0 0.429 S -78.9 -25.4 75.0 0.429 0.0 7JO
HOH
 3.224
2.859
 N
O
 N24
O
5p9y 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 80.0 0.457 S -77.9 -29.5 80.0 0.457 0.0 7JP
HOH
 3.459
2.792
 N
O
 C20
O
5p9z 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 70.0 0.4 S -81.0 -29.1 70.0 0.4 0.0 SAH
7JQ
HOH
 3.186
9.893
2.819
 N
CG2
O
 N3
N2
O
5pa0 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 68.0 0.389 S -75.7 -25.2 68.0 0.389 0.0 SAH
7JR
SO4
HOH
 2.450
9.367
9.648
2.757
 H
HG22
HG21
O
 N3
H73
O2
O
5pa2 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 72.0 0.411 S -75.4 -27.2 72.0 0.411 0.0 SAH
7JU
NHE
HOH
 3.144
9.936
9.552
2.754
 N
CG2
N
O
 N3
N10
C6'
O
5pa3 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 79.0 0.451 S -81.3 -22.1 79.0 0.451 0.0 SAH
7JV
HOH
 3.138
9.977
2.730
 N
CG2
O
 N3
N3
O
5pa4 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 79.0 0.451 S -76.9 -28.9 79.0 0.451 0.0 SAH
7JD
HOH
 3.195
9.818
2.632
 N
CG2
O
 N3
N17
O
5pa5 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 77.0 0.44 S -75.0 -29.4 77.0 0.44 0.0 SAH
7JH
ACT
HOH
 3.209
9.819
4.193
2.787
 N
CG2
CD1
O
 N3
N9
O
O
5pa6 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 69.0 0.394 S -77.8 -28.6 69.0 0.394 0.0 SAH
HOH
 3.220
2.796
 N
O
 N3
O
5pa7 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ILE A:91 A:91 60.0 0.343 S -79.2 -34.8 60.0 0.343 0.0 SAH
7JX
HOH
 3.126
9.284
5.432
 N
CG2
CG1
 N3
CL3
O
ILE B:91 B:91 77.0 0.44 S -72.5 -26.7 NA NA NA
5k09 1 P22734 82.03 7e-135 X-RAY
 2016-09-07 ILE A:90 A:91 80.0 0.457 S -92.5 -25.2 80.0 0.457 0.0 6PQ
HOH
 3.164
9.025
 N
N
 N06
O
ILE B:90 B:91 82.0 0.469 S -80.0 -26.7 NA NA NA
ILE C:90 C:91 81.0 0.463 S -75.5 -26.2 NA NA NA
ILE D:90 D:91 85.0 0.486 S -83.3 -19.9 NA NA NA
ILE E:90 E:91 78.0 0.446 S -82.5 -32.0 NA NA NA
ILE F:90 F:91 80.0 0.457 S -79.1 -32.9 NA NA NA
ILE G:90 G:91 82.0 0.469 S -85.0 -25.4 NA NA NA
ILE H:90 H:91 82.0 0.469 S -71.2 -16.9 NA NA NA
ILE I:90 I:91 83.0 0.474 S -72.3 -29.7 NA NA NA
ILE J:90 J:91 86.0 0.491 S -75.9 -24.4 NA NA NA
ILE K:90 K:91 81.0 0.463 S -74.5 -33.0 NA NA NA
ILE L:90 L:91 81.0 0.463 S -90.7 -26.4 NA NA NA
ILE M:90 M:91 85.0 0.486 S -83.7 -22.8 NA NA NA
ILE N:90 N:91 82.0 0.469 S -88.3 -32.3 NA NA NA
ILE O:90 O:91 88.0 0.503 S -78.5 -14.0 NA NA NA
ILE P:90 P:91 76.0 0.434 S -90.8 -33.8 NA NA NA
ILE Q:90 Q:91 87.0 0.497 S -76.0 -19.8 NA NA NA
ILE R:90 R:91 78.0 0.446 S -77.7 -30.4 NA NA NA
ILE S:90 S:91 83.0 0.474 S -92.3 -17.8 NA NA NA
ILE T:90 T:91 81.0 0.463 S -85.6 -30.9 NA NA NA
ILE U:90 U:91 79.0 0.451 S -74.5 -22.1 NA NA NA
ILE V:90 V:91 76.0 0.434 S -88.1 -32.3 NA NA NA
ILE W:90 W:91 75.0 0.429 S -78.5 -39.8 NA NA NA
ILE X:90 X:91 76.0 0.434 S -93.5 -27.6 NA NA NA
5k0b 1 P22734 81.65 8e-135 X-RAY
 2016-09-07 ILE A:90 A:91 80.0 0.457 S -71.7 -26.7 80.0 0.457 0.0 6PS
PO4
HOH
 3.065
9.479
2.987
 N
CG2
O
 N09
O3
O
ILE B:90 B:91 87.0 0.497 S -85.4 -21.2 NA NA NA
ILE C:90 C:91 60.0 0.343 S -84.0 -21.1 NA NA NA
ILE D:90 D:91 63.0 0.36 S -83.8 -14.1 NA NA NA
ILE E:90 E:91 62.0 0.354 S -93.9 -25.7 NA NA NA
ILE F:90 F:91 75.0 0.429 S -79.5 -33.1 NA NA NA
ILE G:90 G:91 74.0 0.423 S -86.2 -26.7 NA NA NA
ILE H:90 H:91 60.0 0.343 S -84.4 -19.3 NA NA NA
4p7f 1 O88587 81.19 1e-134 X-RAY
 2014-06-11 ILE A:91 A:134 100.0 0.571 S -78.6 -29.5 100.0 0.571 0.0 HOH
 2.284
 H
 O
5k0f 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 ILE A:90 A:91 77.0 0.44 S -80.8 -22.7 77.0 0.44 0.0 NHE
6P1
HOH
 6.450
3.084
2.665
 CG2
N
O
 C4'
N09
O
ILE B:90 B:91 76.0 0.434 S -80.2 -26.6 NA NA NA
5k0g 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 ILE A:90 A:91 74.0 0.423 S -78.8 -24.3 74.0 0.423 0.0 NHE
6PM
HOH
 6.450
2.978
2.635
 CG2
N
O
 C4'
N09
O
ILE B:90 B:91 73.0 0.417 S -79.4 -23.4 NA NA NA
5k0j 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 ILE A:90 A:91 75.0 0.429 S -78.3 -24.0 75.0 0.429 0.0 NHE
6P2
HOH
 6.438
3.077
2.876
 CG2
N
O
 C4'
N12
O
ILE B:90 B:91 77.0 0.44 S -79.2 -25.8 NA NA NA
5k0n 1 P22734 81.94 4e-134 X-RAY
 2016-09-07 ILE A:90 A:91 71.0 0.406 S -78.9 -26.2 71.0 0.406 0.0 NHE
6P0
HOH
 6.523
3.097
2.755
 CG2
N
O
 C4'
N12
O
ILE B:90 B:91 72.0 0.411 S -74.9 -28.8 NA NA NA
ILE C:90 C:91 76.0 0.434 S -72.7 -29.3 NA NA NA
ILE D:90 D:91 72.0 0.411 S -76.7 -31.0 NA NA NA
5k0l 1 P22734 81.94 4e-134 X-RAY
 2016-09-07 ILE A:90 A:91 73.0 0.417 S -78.2 -25.3 73.0 0.417 0.0 6P2
NHE
HOH
 3.141
6.479
2.800
 N
CG2
O
 N12
C4'
O
ILE B:90 B:91 73.0 0.417 S -73.1 -27.6 NA NA NA
ILE C:90 C:91 75.0 0.429 S -74.2 -27.7 NA NA NA
ILE D:90 D:91 77.0 0.44 S -77.6 -25.9 NA NA NA
5k0c 1 P22734 82.33 5e-134 X-RAY
 2016-09-07 ILE A:90 A:91 79.0 0.451 S -80.0 -23.1 79.0 0.451 0.0 NHE
EDO
EDO
6OZ
HOH
 7.523
4.562
3.572
3.056
2.750
 CD1
CG2
CD1
N
O
 C3'
O1
O1
N09
O
ILE B:90 B:91 78.0 0.446 S -79.3 -23.4 NA NA NA
5k0e 1 P22734 82.33 5e-134 X-RAY
 2016-09-07 ILE A:90 A:91 74.0 0.423 S -83.7 -25.3 74.0 0.423 0.0 NHE
6OZ
HOH
 6.667
3.174
2.731
 CG2
N
O
 C4'
N09
O
6aw5 1 ? 81.0 5e-134 X-RAY
 2018-09-12 LYS A:91 A:91 98.0 NA S -76.8 -31.1 98.0 NA NA GOL
HOH
 9.547
2.555
 O
O
 O2
O
6aw6 1 ? 81.0 5e-134 X-RAY
 2018-09-12 LYS A:91 A:91 57.0 NA S -79.1 -37.0 57.0 NA NA SO4
HOH
 4.656
2.486
 CB
O
 O3
O
6aw9 1 ? 81.0 5e-134 X-RAY
 2018-09-12 LYS A:91 A:91 110.0 0.55 S -86.3 -21.5 110.0 0.55 0.0 SAH
HOH
 3.294
4.568
 N
CD
 N3
O
LYS B:91 B:91 95.0 0.475 S -86.6 -7.6 NA NA NA
LYS C:91 C:91 90.0 0.45 S -68.6 -32.7 NA NA NA
6aw4 1 ? 80.54 2e-133 X-RAY
 2018-09-12 LYS A:91 A:91 58.0 NA S -76.6 -32.1 58.0 NA NA GOL
PO4
HOH
 7.774
3.857
2.714
 O
CB
O
 O1
O1
O
6aw7 1 ? 80.54 2e-133 X-RAY
 2018-09-12 LYS A:91 A:91 104.0 0.52 S -87.3 -21.4 104.0 0.52 0.0 SAH
HOH
 3.286
2.516
 N
O
 N3
O
LYS B:91 B:91 78.0 0.39 S -79.1 -27.3 NA NA NA
6aw8 1 ? 80.54 2e-133 X-RAY
 2018-09-12 LYS A:91 A:91 107.0 0.535 S -82.0 -18.0 107.0 0.535 0.0 SAH
HOH
 3.342
2.771
 N
O
 N3
O
LYS B:91 B:91 109.0 0.545 S -87.5 -16.4 NA NA NA
LYS C:91 C:91 101.0 0.505 S -80.2 -21.6 NA NA NA
5k05 1 P22734 82.24 2e-133 X-RAY
 2016-09-07 ILE A:89 A:91 82.0 0.469 S -80.3 -25.2 82.0 0.469 0.0 6P5
HOH
 3.074
3.415
 N
O
 N7
O
ILE B:89 B:91 81.0 0.463 S -80.9 -23.7 NA NA NA
1h1d 1 P22734 81.11 2e-133 X-RAY
 2003-07-17 MET A:91 A:91 73.0 0.395 -79.5 -26.0 73.0 0.395 0.0 SAM
BIA
HOH
 3.032
9.463
4.259
 N
CE
CE
 N3
O17
O
1jr4 1 P22734 81.11 2e-133 X-RAY
 2002-08-10 MET A:91 A:91 92.0 0.497 S -77.7 -26.7 92.0 0.497 0.0 CL4
HOH
 3.134
4.494
 N
SD
 N20
O
1vid 1 P22734 81.11 2e-133 X-RAY
 1996-07-11 MET A:91 A:91 78.0 0.422 S -83.6 -22.2 78.0 0.422 0.0 SAM
DNC
HOH
 3.294
9.534
3.139
 N
CE
CE
 N3
O3
O
2cl5 1 P22734 81.11 2e-133 X-RAY
 2006-06-28 MET A:91 A:91 71.0 0.384 S -84.7 -21.2 71.0 0.384 0.0 SAM
BIE
BU3
HOH
 3.286
9.599
8.427
2.542
 N
CE
CE
O
 N3
O3
C4
O
MET B:91 B:91 75.0 0.405 S -78.1 -20.0 NA NA NA
3hvh 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 MET A:91 A:134 101.0 0.546 -74.3 -26.8 101.0 0.546 0.0 542
HOH
 3.092
2.730
 N
O
 N40
O
3hvi 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 MET A:91 A:134 106.0 0.573 -80.8 -22.0 106.0 0.573 0.0 619
D1D
HOH
 3.093
9.182
2.691
 N
C
O
 N40
C1
O
3hvj 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 MET A:91 A:134 97.0 0.524 S -86.4 -22.0 97.0 0.524 0.0 705
HOH
 3.141
2.844
 N
O
 N40
O
MET B:91 B:134 91.0 0.492 S -87.7 -18.9 NA NA NA
3hvk 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 MET A:91 A:134 86.0 0.465 -81.1 -20.6 86.0 0.465 0.0 719
HOH
 3.104
2.584
 N
O
 N15
O
3nw9 1 P22734 81.11 2e-133 X-RAY
 2011-03-16 MET A:91 A:91 81.0 0.438 -82.6 -20.7 81.0 0.438 0.0 637
HOH
 3.107
3.005
 N
O
 N40
O
3nwb 1 P22734 81.11 2e-133 X-RAY
 2011-08-03 MET A:91 A:91 103.0 0.557 -77.4 -22.5 103.0 0.557 0.0 659
HOH
 2.338
2.703
 H
HE3
 N34
O
3s68 1 P22734 81.11 2e-133 X-RAY
 2012-02-01 MET A:91 A:91 72.0 0.389 -88.3 -18.2 72.0 0.389 0.0 TCW
SAM
HOH
 8.395
2.522
2.730
 HE2
H
O
 O10
N3
O
4p7g 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 MET A:91 A:134 100.0 0.541 S -69.4 -42.5 100.0 0.541 0.0 HOH
 3.306
 SD
 O
MET B:91 B:134 98.0 0.53 S -69.6 -41.1 NA NA NA
MET C:91 C:134 98.0 0.53 S -70.7 -41.5 NA NA NA
MET D:91 D:134 101.0 0.546 S -69.6 -41.4 NA NA NA
4p7j 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 MET A:91 A:134 93.0 0.503 S -77.1 -34.1 93.0 0.503 0.0 HOH
 2.789
 O
 O
4p7k 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 MET A:91 A:134 92.0 0.497 S -84.9 -17.5 92.0 0.497 0.0 HOH
 3.251
 O
 O
4pyl 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 MET A:91 A:134 69.0 0.373 -83.5 -21.8 69.0 0.373 0.0 SFG
TCW
HOH
 3.248
8.585
4.666
 N
CE
CE
 N3
O10
O
5lqc 1 P22734 81.11 2e-133 X-RAY
 2016-08-31 MET A:91 A:91 100.0 0.541 -86.6 -19.4 100.0 0.541 0.0 542
HOH
 3.229
3.242
 N
O
 N40
O
5lqr 1 P22734 81.11 2e-133 X-RAY
 2016-10-05 MET A:91 A:91 90.0 0.486 S -72.8 -29.6 90.0 0.486 0.0 72W
HOH
 3.089
2.484
 N
O
 N15
O
5lqu 1 P22734 81.11 2e-133 X-RAY
 2016-10-05 MET A:91 A:91 105.0 0.568 S -83.8 -21.4 105.0 0.568 0.0 619
HOH
 3.203
2.826
 N
O
 N40
O
MET B:91 B:91 90.0 0.486 S -89.3 -18.6 NA NA NA
5p95 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 MET A:91 A:91 122.0 0.659 -80.8 -19.5 122.0 0.659 0.0 77G
HOH
 3.014
2.804
 SD
O
 N11
O
5p96 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 MET A:91 A:91 104.0 0.562 -80.0 -22.8 104.0 0.562 0.0 77H
HOH
 3.056
2.767
 N
O
 N3
O
5p97 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 MET A:91 A:91 101.0 0.546 S -77.4 -23.7 101.0 0.546 0.0 HOH
 2.753
 O
 O
5p98 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 MET A:91 A:91 106.0 0.573 -74.1 -23.9 106.0 0.573 0.0 HOH
 2.798
 O
 O
5p99 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 MET A:91 A:91 95.0 0.514 -77.9 -24.5 95.0 0.514 0.0 D1D
NHE
HOH
 9.206
9.405
2.797
 O
C
O
 C4
C3'
O
5p9a 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 MET A:91 A:91 103.0 0.557 -79.8 -23.8 103.0 0.557 0.0 77N
HOH
 2.932
2.976
 N
O
 N3
O
5p9b 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 MET A:91 A:91 93.0 0.503 -77.9 -19.8 93.0 0.503 0.0 77P
HOH
 3.150
2.717
 CG
O
 C26
O
5p9c 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 MET A:91 A:91 102.0 0.551 S -74.3 -32.2 102.0 0.551 0.0 HOH
 2.663
 O
 O
5p9d 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 MET A:91 A:91 94.0 0.508 S -75.6 -26.2 94.0 0.508 0.0 77R
HOH
 3.382
2.783
 CG
O
 N8
O
5p9e 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 MET A:91 A:91 95.0 0.514 S -82.0 -29.4 95.0 0.514 0.0 77S
HOH
 3.426
2.651
 N
O
 C21
O
5p9w 1 P22734 81.11 2e-133 X-RAY
 2017-11-22 MET A:91 A:91 117.0 0.632 -78.0 -25.3 117.0 0.632 0.0 7JN
HOH
 3.121
3.003
 N
O
 N17
O
5pa1 1 P22734 81.11 2e-133 X-RAY
 2017-11-22 MET A:91 A:91 76.0 0.411 S -78.8 -26.8 76.0 0.411 0.0 SAH
HOH
 3.229
2.679
 N
O
 N3
O
2zlb 1 P22734 81.11 3e-133 X-RAY
 2008-10-07 MET A:93 A:91 86.0 0.465 S -69.3 -48.7 86.0 0.465 0.0 HOH
 2.941
 N
 O
2zth 1 P22734 81.11 3e-133 X-RAY
 2009-01-13 MET A:93 A:91 87.0 0.47 S -73.4 -24.4 87.0 0.47 0.0 SAM
HOH
 3.103
6.547
 N
CB
 N3
O
2zvj 1 P22734 81.11 3e-133 X-RAY
 2009-01-06 MET A:93 A:91 69.0 0.373 S -88.2 -22.7 69.0 0.373 0.0 SAM
KOM
HOH
 3.301
8.622
3.358
 N
CE
CE
 N3
O15
O
3a7d 1 P22734 81.11 3e-133 X-RAY
 2010-09-15 MET A:93 A:91 120.0 0.649 S -82.4 -24.9 120.0 0.649 0.0 FBN
HOH
 3.445
3.348
 N
O
 N2
O
6gy1 1 P22734 81.11 3e-133 X-RAY
 2018-10-10 MET A:93 A:91 72.0 0.389 -90.4 -11.8 72.0 0.389 0.0 SAH
FGQ
DMS
HOH
 3.270
9.153
7.069
3.790
 N
CE
CE
C
 N3
C14
C2
O
6lfe 1 P22734 81.11 3e-133 X-RAY
 2020-03-04 MET A:93 A:91 72.0 0.389 -84.5 -14.9 72.0 0.389 0.0 SAM
EAO
IPA
PEG
HOH
 3.228
9.569
9.551
7.833
2.784
 N
CE
N
CE
O
 N3
O03
C1
C4
O
5k01 1 P22734 81.78 1e-132 X-RAY
 2016-09-07 ILE A:89 A:91 122.0 0.697 S -76.4 -25.6 122.0 0.697 0.0 6OW
HOH
 2.251
2.983
 H
HG12
 N8
O
5k03 1 P22734 81.78 1e-132 X-RAY
 2016-09-07 ILE A:89 A:91 121.0 0.691 S -78.9 -28.2 121.0 0.691 0.0 6P4
HOH
 3.078
4.526
 N
CG2
 N11
O
4p58 1 O88587 81.6 2e-131 X-RAY
 2014-06-25 ILE A:88 A:134 78.0 0.446 S -76.4 -31.7 78.0 0.446 0.0 2F6
HOH
 3.139
2.672
 N
O
 N13
O
5fhq 1 P22734 81.22 9e-131 X-RAY
 2016-02-03 MET A:89 A:91 74.0 0.4 S -87.3 -15.1 74.0 0.4 0.0 SAM
DNC
HOH
 2.538
9.026
2.408
 H
HE2
HE3
 N3
O4
O
5lqa 1 P22734 81.22 9e-131 X-RAY
 2016-10-05 MET A:89 A:91 106.0 0.573 S -75.2 -26.2 106.0 0.573 0.0 619
HOH
 3.076
2.605
 N
O
 N40
O
5fhr 1 P22734 80.75 2e-129 X-RAY
 2016-02-03 MET A:89 A:134 73.0 0.395 S -92.8 -12.8 73.0 0.395 0.0 SAM
BR
HOH
 3.251
4.042
2.643
 N
CE
O
 N3
BR
O
MET B:89 B:134 86.0 0.465 S -75.0 -29.5 86.0 0.465 0.0 SAM
HOH
 3.193
2.545
 N
O
 N3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21964-f1 1 P21964 100.0 0.0 ILE A:141 A:141 118.0 0.674 S -80.8 -33.9