Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 19951803 . C A CCDS13770.1:NM_000754.3:c.596cCg>cAg_NP_000745.1:p.199P>Q Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4pyi 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 PRO A:149 A:199 49.0 0.338 H -58.2 -39.1 49.0 0.338 0.0 HOH
 2.749
 O
 O
4pyj 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 PRO A:149 A:199 51.0 0.352 H -60.9 -40.0 51.0 0.352 0.0 HOH
 2.639
 O
 O
4pyk 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 PRO A:149 A:199 52.0 0.359 H -52.1 -45.8 52.0 0.359 0.0 HOH
 3.878
 CD
 O
5lsa 1 P21964 100.0 3e-165 X-RAY
 2016-09-07 PRO A:149 A:199 47.0 0.324 H -56.6 -41.1 47.0 0.324 0.0 SAM
HOH
 8.987
2.778
 CG
O
 N6
O
6i3c 1 P21964 99.1 4e-164 X-RAY
 2019-09-18 PRO A:160 A:149 51.0 0.352 H -59.8 -36.9 51.0 0.352 0.0 SAM
HOH
 8.990
2.794
 CG
O
 N6
O
6i3d 1 P21964 99.1 4e-164 X-RAY
 2019-09-18 PRO A:160 A:149 46.0 0.317 H -59.2 -37.3 46.0 0.317 0.0 SFG
HOH
 8.791
2.837
 CG
O
 N6
O
PRO B:160 B:149 44.0 0.303 H -61.7 -32.0 NA NA NA
4xuc 1 P21964 99.54 1e-161 X-RAY
 2015-04-15 PRO A:152 A:199 38.0 0.262 H -58.3 -36.7 38.0 0.262 0.0 SAM
HOH
 8.453
2.685
 CG
O
 N6
O
4xud 1 P21964 99.54 1e-161 X-RAY
 2015-04-15 PRO A:152 A:199 38.0 0.262 H -53.4 -33.7 38.0 0.262 0.0 SAM
HOH
 8.732
2.671
 CG
O
 N6
O
4xue 1 P21964 100.0 1e-159 X-RAY
 2015-04-15 PRO A:149 B:199 41.0 0.283 H -61.3 -31.1 41.0 0.283 0.0 SAM
HOH
 8.796
2.480
 CG
O
 N6
O
PRO B:149 A:199 43.0 0.297 H -59.3 -30.1 NA NA NA
3a7e 1 P21964 100.0 1e-159 X-RAY
 2010-09-15 PRO A:151 A:149 41.0 0.283 H -47.6 -56.0 41.0 0.283 0.0 SAM
HOH
 8.647
3.891
 CG
CD
 N6
O
3bwm 1 P21964 100.0 2e-159 X-RAY
 2008-06-03 PRO A:148 A:149 51.0 0.352 H -63.1 -27.6 51.0 0.352 0.0 SAM
HOH
 9.104
2.674
 CG
O
 N6
O
3bwy 1 Q6ICE6 99.53 5e-159 X-RAY
 2008-06-03 PRO A:148 A:149 48.0 0.331 H -62.4 -31.2 48.0 0.331 0.0 SAM
HOH
 8.793
2.807
 CG
O
 N6
O
3nwe 1 P22734 82.03 6e-135 X-RAY
 2011-08-03 PRO A:149 A:149 46.0 0.317 H -55.2 -41.4 46.0 0.317 0.0 662
HOH
 6.189
3.214
 HB2
HB2
 H39
O
3oe4 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 PRO A:149 A:149 41.0 0.283 H -57.6 -36.5 41.0 0.283 0.0 610
HOH
 9.885
2.799
 CG
O
 C30
O
3oe5 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 PRO A:149 A:149 40.0 0.276 H -61.2 -34.9 40.0 0.276 0.0 611
HOH
 9.788
2.800
 CG
O
 C28
O
3ozr 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 PRO A:149 A:149 41.0 0.283 H -67.2 -33.9 41.0 0.283 0.0 HOH
 2.732
 O
 O
3ozs 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 PRO A:149 A:149 40.0 0.276 H -60.9 -33.2 40.0 0.276 0.0 OZS
HOH
 9.069
2.792
 C
O
 F29
O
3ozt 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 PRO A:149 A:149 41.0 0.283 H -62.5 -31.2 41.0 0.283 0.0 OZZ
HOH
 9.892
2.807
 CG
O
 O31
O
3r6t 1 P22734 82.03 6e-135 X-RAY
 2012-02-01 PRO A:149 A:192 59.0 0.407 H -55.6 -40.6 59.0 0.407 0.0 CL
LU1
DTD
HOH
 9.984
8.649
8.247
2.840
 CB
CB
O
O
 CL
C37
C4
O
3u81 1 P22734 82.03 6e-135 X-RAY
 2012-02-01 PRO A:149 A:149 49.0 0.338 H -54.0 -43.7 49.0 0.338 0.0 SAH
HOH
 7.918
3.097
 HB2
HD3
 HN61
O
4pym 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 PRO A:149 A:192 49.0 0.338 H -54.1 -42.9 49.0 0.338 0.0 HOH
 3.162
 HD3
 O
4pyn 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 PRO A:149 A:192 50.0 0.345 H -53.1 -43.9 50.0 0.345 0.0 SAH
CL
HOH
 7.967
5.844
3.042
 HB2
HD3
HD3
 HN61
CL
O
4pyo 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 PRO A:149 A:192 50.0 0.345 H -53.7 -43.3 50.0 0.345 0.0 SAH
HOH
 9.144
3.362
 CB
CD
 N6
O
PRO B:149 B:192 49.0 0.338 H -57.7 -44.1 NA NA NA
4pyq 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 PRO A:149 A:192 44.0 0.303 H -68.8 -28.3 44.0 0.303 0.0 2X1
ACT
HOH
 7.060
6.384
2.623
 HG3
HG2
O
 N11
O
O
PRO B:149 B:192 49.0 0.338 H -55.0 -41.9 49.0 0.338 0.0 2X1
ACT
HOH
 6.837
6.690
2.884
 HG2
HB2
O
 N6
OXT
O
5lqj 1 P22734 82.03 6e-135 X-RAY
 2016-09-28 PRO A:149 A:149 40.0 0.276 H -53.3 -37.7 40.0 0.276 0.0 72N
HOH
 8.305
2.685
 N
O
 C6
O
PRO B:149 B:149 44.0 0.303 H -62.7 -28.2 NA NA NA
PRO C:149 C:149 44.0 0.303 H -62.9 -16.7 NA NA NA
PRO D:149 D:149 42.0 0.29 H -58.6 -29.6 NA NA NA
5lqk 1 P22734 82.03 6e-135 X-RAY
 2016-08-31 PRO A:149 A:149 43.0 0.297 H -61.2 -32.5 43.0 0.297 0.0 72M
HOH
 8.575
2.702
 CG
O
 N31
O
5lqn 1 P22734 82.03 6e-135 X-RAY
 2016-10-05 PRO A:149 A:149 43.0 0.297 H -57.1 -39.6 43.0 0.297 0.0 72O
HOH
 7.467
3.370
 CG
CB
 CL1
O
5lr6 1 P22734 82.03 6e-135 X-RAY
 2016-08-31 PRO A:149 A:149 62.0 0.428 H -64.0 -30.6 62.0 0.428 0.0 731
NHE
HOH
 8.614
8.996
3.316
 CG
CD
O
 C21
O2
O
PRO B:149 B:149 59.0 0.407 H -63.0 -38.1 NA NA NA
PRO C:149 C:149 60.0 0.414 H -62.8 -32.9 NA NA NA
PRO D:149 D:149 61.0 0.421 H -62.8 -37.5 NA NA NA
5p8w 1 P22734 82.03 6e-135 X-RAY
 2016-09-07 PRO A:149 A:149 65.0 0.448 H -53.5 -41.5 65.0 0.448 0.0 O01
FMT
HOH
 8.887
6.272
2.733
 CB
CD
O
 C6
O2
O
PRO B:149 B:149 60.0 0.414 H -60.2 -37.0 60.0 0.414 0.0 O01
FMT
HOH
 8.487
6.274
2.674
 CG
CD
O
 C6
O1
O
PRO C:149 C:149 42.0 0.29 H -51.5 -43.3 42.0 0.29 0.0 O01
HOH
 8.617
2.644
 CB
O
 C6
O
5p8x 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 PRO A:149 A:149 43.0 0.297 H -59.6 -37.1 43.0 0.297 0.0 75Z
HOH
 9.200
2.791
 CG
O
 C33
O
5p8y 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 PRO A:149 A:149 40.0 0.276 H -59.3 -35.9 40.0 0.276 0.0 763
NHE
HOH
 9.575
9.335
3.742
 CG
CD
CD
 C31
O3
O
5p8z 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 PRO A:149 A:149 41.0 0.283 H -62.3 -33.5 41.0 0.283 0.0 HOH
 2.827
 O
 O
5p90 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 PRO A:149 A:149 41.0 0.283 H -58.6 -35.5 41.0 0.283 0.0 769
NHE
HOH
 9.819
9.374
2.808
 CG
CD
O
 C31
O3
O
5p91 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 PRO A:149 A:149 42.0 0.29 H -57.7 -38.7 42.0 0.29 0.0 76B
HOH
 9.147
2.800
 CG
O
 C32
O
5p92 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 PRO A:149 A:149 40.0 0.276 H -61.9 -34.3 40.0 0.276 0.0 HOH
 2.791
 O
 O
5p93 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 PRO A:149 A:149 42.0 0.29 H -60.7 -36.6 42.0 0.29 0.0 76S
HOH
 9.718
2.803
 CG
O
 C28
O
5p94 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 PRO A:149 A:149 42.0 0.29 H -57.7 -41.0 42.0 0.29 0.0 HOH
 2.797
 O
 O
5p9n 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 57.0 0.393 H -57.9 -40.1 57.0 0.393 0.0 7JE
8JE
HOH
 9.075
9.067
2.805
 CG
CG
O
 C37
C37
O
5p9o 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 47.0 0.324 H -60.0 -39.0 47.0 0.324 0.0 SAH
HOH
 9.199
3.281
 CG
C
 N6
O
5p9p 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 48.0 0.331 H -59.4 -39.4 48.0 0.331 0.0 SAH
HOH
 9.016
2.826
 CG
O
 N6
O
5p9q 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 48.0 0.331 H -58.5 -39.8 48.0 0.331 0.0 SAH
ACT
HOH
 9.118
7.819
2.789
 CG
CG
O
 N6
CH3
O
5p9r 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 44.0 0.303 H -66.7 -34.1 44.0 0.303 0.0 SAH
HOH
 8.776
2.923
 CG
O
 N6
O
PRO B:149 B:149 46.0 0.317 H -60.9 -37.1 NA NA NA
5p9s 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 41.0 0.283 H -51.9 -47.6 41.0 0.283 0.0 SAH
HOH
 8.819
3.701
 CB
CD
 N6
O
5p9t 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 46.0 0.317 H -57.9 -39.5 46.0 0.317 0.0 SAH
HOH
 9.299
3.784
 CG
CD
 N6
O
5p9u 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 40.0 0.276 H -61.4 -34.2 40.0 0.276 0.0 SAH
HOH
 8.792
3.869
 CG
CD
 N6
O
5p9v 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 47.0 0.324 H -59.6 -40.0 47.0 0.324 0.0 SAH
CXS
HOH
 9.207
8.625
2.808
 CG
O
O
 N6
C6
O
5p9x 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 42.0 0.29 H -57.1 -38.3 42.0 0.29 0.0 7JO
HOH
 8.940
2.809
 CG
O
 N34
O
5p9y 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 40.0 0.276 H -58.6 -35.4 40.0 0.276 0.0 7JP
NHE
HOH
 9.768
8.607
2.812
 CG
O
O
 C25
C3'
O
5p9z 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 45.0 0.31 H -56.7 -39.8 45.0 0.31 0.0 SAH
HOH
 8.818
2.833
 CG
O
 N6
O
5pa0 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 43.0 0.297 H -56.9 -37.8 43.0 0.297 0.0 SAH
CXS
HOH
 7.345
7.627
2.912
 HG2
O
HB2
 HN62
H62
O
5pa2 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 48.0 0.331 H -57.7 -40.9 48.0 0.331 0.0 SAH
HOH
 9.388
2.801
 CG
O
 N6
O
5pa3 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 44.0 0.303 H -59.2 -39.0 44.0 0.303 0.0 SAH
HOH
 9.083
2.782
 CG
O
 N6
O
5pa4 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 45.0 0.31 H -56.5 -33.9 45.0 0.31 0.0 SAH
HOH
 8.865
2.706
 CG
O
 N6
O
5pa5 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 48.0 0.331 H -58.5 -39.8 48.0 0.331 0.0 SAH
ACT
HOH
 9.118
7.819
2.789
 CG
CG
O
 N6
CH3
O
5pa6 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 45.0 0.31 H -55.3 -41.9 45.0 0.31 0.0 SAH
HOH
 8.938
2.825
 CB
O
 N6
O
5pa7 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 PRO A:149 A:149 47.0 0.324 H -62.0 -33.7 47.0 0.324 0.0 SAH
HOH
 8.861
4.383
 CG
CD
 N6
O
PRO B:149 B:149 50.0 0.345 H -48.6 -48.8 NA NA NA
5k09 1 P22734 82.03 7e-135 X-RAY
 2016-09-07 PRO A:148 A:149 48.0 0.331 H -65.9 -37.0 48.0 0.331 0.0 6PQ
HOH
 8.941
3.821
 CG
CD
 C19
O
PRO B:148 B:149 53.0 0.366 H -63.8 -36.2 NA NA NA
PRO C:148 C:149 53.0 0.366 H -73.5 -14.6 NA NA NA
PRO D:148 D:149 50.0 0.345 H -66.9 -25.4 NA NA NA
PRO E:148 E:149 66.0 0.455 H -74.2 -18.4 NA NA NA
PRO F:148 F:149 50.0 0.345 H -65.9 -27.7 NA NA NA
PRO G:148 G:149 61.0 0.421 H -64.3 -26.9 NA NA NA
PRO H:148 H:149 51.0 0.352 H -60.8 -32.1 NA NA NA
PRO I:148 I:149 49.0 0.338 H -68.6 -20.0 NA NA NA
PRO J:148 J:149 58.0 0.4 H -61.7 -40.1 NA NA NA
PRO K:148 K:149 49.0 0.338 H -68.5 -26.9 NA NA NA
PRO L:148 L:149 50.0 0.345 H -67.0 -25.7 NA NA NA
PRO M:148 M:149 49.0 0.338 H -64.5 -25.7 NA NA NA
PRO N:148 N:149 66.0 0.455 H -67.2 -29.3 NA NA NA
PRO O:148 O:149 65.0 0.448 H -57.0 -41.7 NA NA NA
PRO P:148 P:149 47.0 0.324 H -67.1 -29.5 NA NA NA
PRO Q:148 Q:149 48.0 0.331 H -60.9 -30.2 NA NA NA
PRO R:148 R:149 68.0 0.469 H -65.8 -33.3 NA NA NA
PRO S:148 S:149 51.0 0.352 H -71.6 -14.4 NA NA NA
PRO T:148 T:149 50.0 0.345 H -57.0 -45.3 NA NA NA
PRO U:148 U:149 49.0 0.338 H -62.9 -28.6 NA NA NA
PRO V:148 V:149 48.0 0.331 H -71.5 -23.2 NA NA NA
PRO W:148 W:149 65.0 0.448 H -68.6 -22.7 NA NA NA
PRO X:148 X:149 53.0 0.366 H -60.1 -34.5 NA NA NA
5k0b 1 P22734 81.65 8e-135 X-RAY
 2016-09-07 PRO A:148 A:149 59.0 0.407 H -60.9 -33.6 59.0 0.407 0.0 6PS
HOH
 8.595
2.801
 CG
O
 C01
O
PRO B:148 B:149 39.0 0.269 H -63.8 -32.2 NA NA NA
PRO C:148 C:149 44.0 0.303 H -59.1 -37.1 NA NA NA
PRO D:148 D:149 43.0 0.297 H -54.8 -39.8 NA NA NA
PRO E:148 E:149 46.0 0.317 H -70.8 -24.8 NA NA NA
PRO F:148 F:149 59.0 0.407 H -65.1 -29.0 NA NA NA
PRO G:148 G:149 61.0 0.421 H -55.0 -41.3 NA NA NA
PRO H:148 H:149 41.0 0.283 H -62.4 -33.0 NA NA NA
4p7f 1 O88587 81.19 1e-134 X-RAY
 2014-06-11 PRO A:149 A:192 44.0 0.303 H -62.2 -33.8 44.0 0.303 0.0 HOH
 2.709
 O
 O
5k0f 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 PRO A:148 A:149 60.0 0.414 H -63.5 -32.3 60.0 0.414 0.0 6P1
HOH
 8.322
2.792
 CG
O
 C06
O
PRO B:148 B:149 59.0 0.407 H -62.8 -34.1 NA NA NA
5k0g 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 PRO A:148 A:149 59.0 0.407 H -62.6 -34.8 59.0 0.407 0.0 6PM
HOH
 8.404
2.712
 CG
O
 C06
O
PRO B:148 B:149 60.0 0.414 H -62.4 -35.2 NA NA NA
5k0j 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 PRO A:148 A:149 56.0 0.386 H -65.0 -31.3 56.0 0.386 0.0 6P2
HOH
 8.298
2.947
 CG
O
 C09
O
PRO B:148 B:149 58.0 0.4 H -64.4 -34.0 NA NA NA
5k0n 1 P22734 81.94 4e-134 X-RAY
 2016-09-07 PRO A:148 A:149 61.0 0.421 H -57.0 -43.8 61.0 0.421 0.0 6P0
HOH
 8.815
3.006
 CB
O
 C09
O
PRO B:148 B:149 56.0 0.386 H -62.6 -33.4 NA NA NA
PRO C:148 C:149 57.0 0.393 H -67.0 -34.2 NA NA NA
PRO D:148 D:149 61.0 0.421 H -65.0 -33.8 NA NA NA
5k0l 1 P22734 81.94 4e-134 X-RAY
 2016-09-07 PRO A:148 A:149 59.0 0.407 H -66.4 -29.6 59.0 0.407 0.0 6P2
HOH
 8.356
2.963
 CG
O
 C09
O
PRO B:148 B:149 56.0 0.386 H -62.1 -32.8 NA NA NA
PRO C:148 C:149 56.0 0.386 H -67.5 -33.9 NA NA NA
PRO D:148 D:149 58.0 0.4 H -66.4 -28.5 NA NA NA
5k0c 1 P22734 82.33 5e-134 X-RAY
 2016-09-07 PRO A:148 A:149 59.0 0.407 H -67.4 -33.4 59.0 0.407 0.0 NHE
EDO
6OZ
HOH
 9.109
9.337
8.416
2.612
 CD
CG
CG
O
 O2
O2
C19
O
PRO B:148 B:149 60.0 0.414 H -67.6 -31.3 NA NA NA
5k0e 1 P22734 82.33 5e-134 X-RAY
 2016-09-07 PRO A:148 A:149 64.0 0.441 H -61.4 -27.0 64.0 0.441 0.0 6OZ
HOH
 8.352
2.794
 CG
O
 C19
O
6aw5 1 ? 81.0 5e-134 X-RAY
 2018-09-12 PRO A:148 A:148 36.0 0.248 H -60.3 -34.2 36.0 0.248 0.0 HOH
 2.827
 O
 O
6aw6 1 ? 81.0 5e-134 X-RAY
 2018-09-12 PRO A:148 A:148 44.0 0.303 H -54.9 -40.0 44.0 0.303 0.0 SO4
HOH
 5.991
2.670
 CB
O
 O4
O
6aw9 1 ? 81.0 5e-134 X-RAY
 2018-09-12 PRO A:148 A:148 51.0 0.352 H -66.1 -34.3 51.0 0.352 0.0 SAH
HOH
 8.993
8.627
 CG
CG
 N6
O
PRO B:148 B:148 44.0 0.303 H -61.6 -37.5 NA NA NA
PRO C:148 C:148 48.0 0.331 H -62.3 -30.8 NA NA NA
6aw4 1 ? 80.54 2e-133 X-RAY
 2018-09-12 PRO A:148 A:148 35.0 0.241 H -63.1 -32.5 35.0 0.241 0.0 PO4
HOH
 6.923
2.810
 CG
O
 O3
O
6aw7 1 ? 80.54 2e-133 X-RAY
 2018-09-12 PRO A:148 A:148 48.0 0.331 H -65.5 -35.8 48.0 0.331 0.0 SAH
HOH
 9.089
4.123
 CG
CD
 N6
O
PRO B:148 B:148 50.0 0.345 H -62.0 -33.4 NA NA NA
6aw8 1 ? 80.54 2e-133 X-RAY
 2018-09-12 PRO A:148 A:148 50.0 0.345 H -59.5 -36.5 50.0 0.345 0.0 SAH
HOH
 9.399
2.700
 CB
O
 N6
O
PRO B:148 B:148 44.0 0.303 H -57.2 -36.7 NA NA NA
PRO C:148 C:148 48.0 0.331 H -59.6 -38.7 NA NA NA
5k05 1 P22734 82.24 2e-133 X-RAY
 2016-09-07 PRO A:147 A:149 42.0 0.29 H -57.8 -37.0 42.0 0.29 0.0 6P5
HOH
 7.147
2.596
 CB
O
 C14
O
PRO B:147 B:149 46.0 0.317 H -61.2 -37.7 NA NA NA
1h1d 1 P22734 81.11 2e-133 X-RAY
 2003-07-17 PRO A:149 A:149 42.0 0.29 H -56.2 -38.0 42.0 0.29 0.0 SAM
HOH
 8.412
2.796
 CG
O
 N6
O
1jr4 1 P22734 81.11 2e-133 X-RAY
 2002-08-10 PRO A:149 A:149 42.0 0.29 H -53.6 -45.2 42.0 0.29 0.0 CL4
HOH
 8.171
3.822
 CG
CD
 N17
O
1vid 1 P22734 81.11 2e-133 X-RAY
 1996-07-11 PRO A:149 A:149 44.0 0.303 H -56.5 -36.8 44.0 0.303 0.0 SAM
HOH
 8.578
3.070
 CG
O
 N6
O
2cl5 1 P22734 81.11 2e-133 X-RAY
 2006-06-28 PRO A:149 A:149 41.0 0.283 H -60.9 -34.8 41.0 0.283 0.0 SAM
BU3
HOH
 8.696
7.721
2.779
 CG
CD
O
 N6
C3
O
PRO B:149 B:149 42.0 0.29 H -56.8 -37.7 NA NA NA
3hvh 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 PRO A:149 A:192 43.0 0.297 H -54.1 -43.2 43.0 0.297 0.0 542
CXS
HOH
 7.937
8.563
3.434
 CB
O
O
 C36
C6
O
3hvi 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 PRO A:149 A:192 45.0 0.31 H -53.4 -44.6 45.0 0.31 0.0 619
HOH
 8.035
3.443
 CB
O
 C36
O
3hvj 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 PRO A:149 A:192 37.0 0.255 H -58.2 -43.0 37.0 0.255 0.0 705
HOH
 8.262
2.608
 CB
O
 C36
O
PRO B:149 B:192 37.0 0.255 H -52.9 -43.1 NA NA NA
3hvk 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 PRO A:149 A:192 43.0 0.297 H -56.5 -41.1 43.0 0.297 0.0 719
HOH
 8.037
3.506
 CB
O
 C39
O
3nw9 1 P22734 81.11 2e-133 X-RAY
 2011-03-16 PRO A:149 A:149 60.0 0.414 H -58.2 -39.4 60.0 0.414 0.0 637
HOH
 8.776
2.788
 CB
O
 C7
O
3nwb 1 P22734 81.11 2e-133 X-RAY
 2011-08-03 PRO A:149 A:149 43.0 0.297 H -55.3 -42.0 43.0 0.297 0.0 659
HOH
 6.344
3.087
 HB2
HB2
 H39
O
3s68 1 P22734 81.11 2e-133 X-RAY
 2012-02-01 PRO A:149 A:149 41.0 0.283 H -53.6 -44.5 41.0 0.283 0.0 CL
SAM
HOH
 4.689
7.448
3.173
 HB3
HB2
HB3
 CL
HN61
O
4p7g 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 PRO A:149 A:192 71.0 0.49 H -54.3 -37.9 71.0 0.49 0.0 HOH
 3.554
 CB
 O
PRO B:149 B:192 62.0 0.428 H -54.7 -38.1 NA NA NA
PRO C:149 C:192 62.0 0.428 H -53.6 -37.3 NA NA NA
PRO D:149 D:192 70.0 0.483 H -53.9 -37.5 NA NA NA
4p7j 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 PRO A:149 A:192 70.0 0.483 H -61.8 -33.1 70.0 0.483 0.0 HOH
 2.674
 O
 O
4p7k 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 PRO A:149 A:192 49.0 0.338 H -53.9 -44.3 49.0 0.338 0.0 SFG
HOH
 7.614
2.900
 HB2
HD3
 HN62
O
4pyl 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 PRO A:149 A:192 42.0 0.29 H -58.1 -42.0 42.0 0.29 0.0 SFG
HOH
 8.674
2.725
 CB
O
 N6
O
5lqc 1 P22734 81.11 2e-133 X-RAY
 2016-08-31 PRO A:149 A:149 44.0 0.303 H -52.8 -46.8 44.0 0.303 0.0 542
HOH
 8.098
3.519
 CB
CB
 C36
O
5lqr 1 P22734 81.11 2e-133 X-RAY
 2016-10-05 PRO A:149 A:149 43.0 0.297 H -50.2 -44.6 43.0 0.297 0.0 72W
HOH
 8.257
3.389
 CB
O
 C38
O
5lqu 1 P22734 81.11 2e-133 X-RAY
 2016-10-05 PRO A:149 A:149 40.0 0.276 H -56.6 -42.9 40.0 0.276 0.0 619
HOH
 7.965
2.547
 CB
O
 C36
O
PRO B:149 B:149 39.0 0.269 H -52.7 -43.8 NA NA NA
5p95 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 PRO A:149 A:149 40.0 0.276 H -57.6 -39.6 40.0 0.276 0.0 77G
HOH
 9.350
3.289
 CG
O
 C16
O
5p96 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 PRO A:149 A:149 40.0 0.276 H -58.5 -37.8 40.0 0.276 0.0 77H
HOH
 8.352
3.756
 CG
CD
 N33
O
5p97 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 PRO A:149 A:149 40.0 0.276 H -60.8 -36.4 40.0 0.276 0.0 CL
HOH
 9.259
3.198
 CG
O
 CL
O
5p98 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 PRO A:149 A:149 42.0 0.29 H -58.6 -38.2 42.0 0.29 0.0 HOH
 3.158
 O
 O
5p99 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 PRO A:149 A:149 42.0 0.29 H -59.2 -38.4 42.0 0.29 0.0 HOH
 3.238
 O
 O
5p9a 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 PRO A:149 A:149 41.0 0.283 H -58.1 -37.3 41.0 0.283 0.0 77N
HOH
 8.752
2.786
 CG
O
 N22
O
5p9b 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 PRO A:149 A:149 42.0 0.29 H -55.3 -41.8 42.0 0.29 0.0 NHE
HOH
 8.523
3.144
 O
O
 C5'
O
5p9c 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 PRO A:149 A:149 39.0 0.269 H -57.3 -36.9 39.0 0.269 0.0 77Q
SO4
HOH
 9.434
9.394
2.811
 CG
CD
O
 C28
O2
O
5p9d 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 PRO A:149 A:149 41.0 0.283 H -57.2 -38.5 41.0 0.283 0.0 HOH
 2.749
 O
 O
5p9e 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 PRO A:149 A:149 40.0 0.276 H -60.1 -37.1 40.0 0.276 0.0 HOH
 2.778
 O
 O
5p9w 1 P22734 81.11 2e-133 X-RAY
 2017-11-22 PRO A:149 A:149 44.0 0.303 H -56.2 -42.3 44.0 0.303 0.0 7JN
SO4
HOH
 7.898
9.266
3.440
 CB
CD
O
 C39
O2
O
5pa1 1 P22734 81.11 2e-133 X-RAY
 2017-11-22 PRO A:149 A:149 42.0 0.29 H -56.3 -41.5 42.0 0.29 0.0 SAH
HOH
 8.914
3.734
 CG
CD
 N6
O
2zlb 1 P22734 81.11 3e-133 X-RAY
 2008-10-07 PRO A:151 A:149 70.0 0.483 H -54.8 -31.0 70.0 0.483 0.0 HOH
 2.663
 O
 O
2zth 1 P22734 81.11 3e-133 X-RAY
 2009-01-13 PRO A:151 A:149 46.0 0.317 H -51.3 -49.0 46.0 0.317 0.0 SAM
HOH
 8.969
6.978
 CB
CD
 N6
O
2zvj 1 P22734 81.11 3e-133 X-RAY
 2009-01-06 PRO A:151 A:149 41.0 0.283 H -57.3 -48.2 41.0 0.283 0.0 SAM
HOH
 8.770
2.812
 CG
O
 N6
O
3a7d 1 P22734 81.11 3e-133 X-RAY
 2010-09-15 PRO A:151 A:149 40.0 0.276 H -49.7 -45.3 40.0 0.276 0.0 FBN
HOH
 8.975
2.738
 CG
O
 N11
O
6gy1 1 P22734 81.11 3e-133 X-RAY
 2018-10-10 PRO A:151 A:149 43.0 0.297 H -54.9 -44.1 43.0 0.297 0.0 SAH
HOH
 8.995
2.799
 CB
O
 N6
O
6lfe 1 P22734 81.11 3e-133 X-RAY
 2020-03-04 PRO A:151 A:149 46.0 0.317 H -55.7 -41.6 46.0 0.317 0.0 SAM
HOH
 8.889
2.755
 CB
O
 N6
O
5k01 1 P22734 81.78 1e-132 X-RAY
 2016-09-07 PRO A:147 A:149 51.0 0.352 H -52.1 -44.3 51.0 0.352 0.0 6OW
HOH
 7.210
2.830
 HB2
HD3
 H163
O
5k03 1 P22734 81.78 1e-132 X-RAY
 2016-09-07 PRO A:147 A:149 51.0 0.352 H -59.0 -38.8 51.0 0.352 0.0 6P4
HOH
 9.289
3.617
 CB
CD
 C8
O
4p58 1 O88587 81.6 2e-131 X-RAY
 2014-06-25 PRO A:146 A:192 47.0 0.324 H -54.9 -42.2 47.0 0.324 0.0 2F6
HOH
 9.070
3.880
 CB
CD
 C5
O
5fhq 1 P22734 81.22 9e-131 X-RAY
 2016-02-03 PRO A:147 A:149 43.0 0.297 H -63.4 -32.4 43.0 0.297 0.0 SAM
HOH
 6.669
2.750
 HG2
O
 HN61
O
5lqa 1 P22734 81.22 9e-131 X-RAY
 2016-10-05 PRO A:147 A:149 43.0 0.297 H -53.8 -42.7 43.0 0.297 0.0 619
HOH
 7.888
2.832
 CB
O
 C36
O
5fhr 1 P22734 80.75 2e-129 X-RAY
 2016-02-03 PRO A:147 A:192 47.0 0.324 H -57.6 -37.9 47.0 0.324 0.0 SAM
HOH
 8.810
2.614
 CB
O
 N6
O
PRO B:147 B:192 44.0 0.303 H -64.6 -32.0 44.0 0.303 0.0 SAM
HOH
 8.762
2.780
 CG
O
 N6
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21964-f1 1 P21964 100.0 0.0 PRO A:199 A:199 43.0 0.297 H -64.0 -30.7