Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 19956125 . G A CCDS13770.1:NM_000754.3:c.682Gac>Aac_NP_000745.1:p.228D>N Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4pyi 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 ASP A:178 A:228 108.0 0.72 H -65.1 -42.9 108.0 0.72 0.0 HOH
 2.016
 H
 O
4pyj 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 ASP A:178 A:228 119.0 0.793 H -69.4 -38.4 119.0 0.793 0.0 HOH
 2.749
 O
 O
4pyk 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 ASP A:178 A:228 121.0 0.807 H -65.7 -35.4 121.0 0.807 0.0 HOH
 2.582
 O
 O
5lsa 1 P21964 100.0 3e-165 X-RAY
 2016-09-07 ASP A:178 A:228 118.0 0.787 H -71.4 -41.3 118.0 0.787 0.0 HOH
 2.598
 OD2
 O
6i3c 1 P21964 99.1 4e-164 X-RAY
 2019-09-18 ASP A:189 A:178 121.0 0.807 H -68.8 -40.8 121.0 0.807 0.0 HOH
 2.642
 OD1
 O
6i3d 1 P21964 99.1 4e-164 X-RAY
 2019-09-18 ASP A:189 A:178 122.0 0.813 H -67.7 -40.4 122.0 0.813 0.0 HOH
 2.859
 OD2
 O
ASP B:189 B:178 72.0 0.48 H -68.5 -38.6 NA NA NA
4xuc 1 P21964 99.54 1e-161 X-RAY
 2015-04-15 ASP A:181 A:228 72.0 0.48 H -68.1 -39.7 72.0 0.48 0.0 HOH
 2.536
 OD1
 O
4xud 1 P21964 99.54 1e-161 X-RAY
 2015-04-15 ASP A:181 A:228 72.0 0.48 H -68.2 -43.5 72.0 0.48 0.0 HOH
 2.591
 OD1
 O
4xue 1 P21964 100.0 1e-159 X-RAY
 2015-04-15 ASP A:178 B:228 73.0 0.487 H -64.3 -45.6 73.0 0.487 0.0 43J
HOH
 8.793
2.580
 OD1
OD2
 C17
O
ASP B:178 A:228 74.0 0.493 H -65.1 -37.6 NA NA NA
3a7e 1 P21964 100.0 1e-159 X-RAY
 2010-09-15 ASP A:180 A:178 72.0 0.48 H -70.0 -38.6 72.0 0.48 0.0 HOH
 2.666
 OD2
 O
3bwm 1 P21964 100.0 2e-159 X-RAY
 2008-06-03 ASP A:177 A:178 114.0 0.76 H -76.3 -29.6 114.0 0.76 0.0 HOH
 2.611
 O
 O
3bwy 1 Q6ICE6 99.53 5e-159 X-RAY
 2008-06-03 ASP A:177 A:178 117.0 0.78 H -66.0 -42.2 117.0 0.78 0.0 HOH
 2.748
 OD1
 O
3nwe 1 P22734 82.03 6e-135 X-RAY
 2011-08-03 ASP A:178 A:178 75.0 0.5 H -65.9 -47.2 75.0 0.5 0.0 HOH
 2.713
 OD1
 O
3oe4 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ASP A:178 A:178 77.0 0.513 H -64.9 -47.5 77.0 0.513 0.0 HOH
 2.590
 OD2
 O
3oe5 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ASP A:178 A:178 75.0 0.5 H -63.6 -45.9 75.0 0.5 0.0 HOH
 2.560
 OD2
 O
3ozr 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ASP A:178 A:178 76.0 0.507 H -64.1 -46.3 76.0 0.507 0.0 HOH
 2.583
 OD1
 O
3ozs 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ASP A:178 A:178 75.0 0.5 H -64.7 -47.8 75.0 0.5 0.0 HOH
 2.557
 OD2
 O
3ozt 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ASP A:178 A:178 79.0 0.527 H -65.5 -47.4 79.0 0.527 0.0 HOH
 2.549
 OD2
 O
3r6t 1 P22734 82.03 6e-135 X-RAY
 2012-02-01 ASP A:178 A:221 75.0 0.5 H -62.7 -48.7 75.0 0.5 0.0 HOH
 2.621
 OD2
 O
3u81 1 P22734 82.03 6e-135 X-RAY
 2012-02-01 ASP A:178 A:178 120.0 0.8 H -71.1 -38.9 120.0 0.8 0.0 HOH
 2.496
 H
 O
4pym 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ASP A:178 A:221 121.0 0.807 H -67.9 -41.0 121.0 0.807 0.0 HOH
 2.633
 H
 O
4pyn 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ASP A:178 A:221 118.0 0.787 H -70.8 -37.9 118.0 0.787 0.0 CL
HOH
 2.490
2.672
 H
OD1
 CL
O
4pyo 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ASP A:178 A:221 123.0 0.82 H -62.1 -47.5 123.0 0.82 0.0 HOH
 2.996
 N
 O
ASP B:178 B:221 119.0 0.793 H -59.8 -44.6 NA NA NA
4pyq 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ASP A:178 A:221 114.0 0.76 H -78.8 -42.4 114.0 0.76 0.0 HOH
 2.923
 HB2
 O
ASP B:178 B:221 115.0 0.767 H -68.4 -41.5 115.0 0.767 0.0 HOH
 2.458
 HB2
 O
5lqj 1 P22734 82.03 6e-135 X-RAY
 2016-09-28 ASP A:178 A:178 71.0 0.473 H -65.0 -40.7 71.0 0.473 0.0 72N
HOH
 3.724
2.978
 CB
OD1
 C10
O
ASP B:178 B:178 63.0 0.42 H -64.1 -46.9 NA NA NA
ASP C:178 C:178 69.0 0.46 H -72.9 -37.7 NA NA NA
ASP D:178 D:178 64.0 0.427 H -60.8 -43.8 NA NA NA
5lqk 1 P22734 82.03 6e-135 X-RAY
 2016-08-31 ASP A:178 A:178 77.0 0.513 H -64.9 -41.4 77.0 0.513 0.0 HOH
 2.886
 OD1
 O
5lqn 1 P22734 82.03 6e-135 X-RAY
 2016-10-05 ASP A:178 A:178 117.0 0.78 H -70.3 -45.2 117.0 0.78 0.0 HOH
 2.860
 O
 O
5lr6 1 P22734 82.03 6e-135 X-RAY
 2016-08-31 ASP A:178 A:178 118.0 0.787 H -70.3 -44.4 118.0 0.787 0.0 NHE
HOH
 9.022
3.584
 OD2
O
 O2
O
ASP B:178 B:178 115.0 0.767 H -68.1 -53.1 NA NA NA
ASP C:178 C:178 116.0 0.773 H -71.0 -43.0 NA NA NA
ASP D:178 D:178 117.0 0.78 H -79.5 -50.6 NA NA NA
5p8w 1 P22734 82.03 6e-135 X-RAY
 2016-09-07 ASP A:178 A:178 123.0 0.82 H -64.3 -44.6 123.0 0.82 0.0 FMT
HOH
 2.820
2.766
 N
OD2
 O1
O
ASP B:178 B:178 117.0 0.78 H -71.7 -39.2 117.0 0.78 0.0 FMT
HOH
 2.963
2.580
 N
OD1
 O2
O
ASP C:178 C:178 118.0 0.787 H -66.5 -41.5 104.0 0.693 0.094 B:P22734:0.093
 HOH
 2.295
 OD1
 O
5p8x 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ASP A:178 A:178 77.0 0.513 H -67.0 -45.8 77.0 0.513 0.0 HOH
 2.540
 OD2
 O
5p8y 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ASP A:178 A:178 76.0 0.507 H -66.3 -43.6 76.0 0.507 0.0 NHE
HOH
 8.240
2.540
 OD1
OD2
 O3
O
5p8z 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ASP A:178 A:178 75.0 0.5 H -68.0 -44.4 75.0 0.5 0.0 HOH
 2.495
 OD2
 O
5p90 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ASP A:178 A:178 75.0 0.5 H -68.3 -43.6 75.0 0.5 0.0 NHE
HOH
 8.299
2.551
 OD1
OD2
 O3
O
5p91 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ASP A:178 A:178 77.0 0.513 H -68.0 -44.7 77.0 0.513 0.0 HOH
 2.585
 OD2
 O
5p92 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ASP A:178 A:178 76.0 0.507 H -68.4 -43.7 76.0 0.507 0.0 HOH
 2.537
 OD1
 O
5p93 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ASP A:178 A:178 76.0 0.507 H -68.8 -44.5 76.0 0.507 0.0 HOH
 2.591
 OD2
 O
5p94 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ASP A:178 A:178 76.0 0.507 H -67.6 -45.9 76.0 0.507 0.0 HOH
 2.606
 OD2
 O
5p9n 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 74.0 0.493 H -69.2 -46.5 74.0 0.493 0.0 HOH
 2.414
 OD2
 O
5p9o 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 68.0 0.453 H -66.4 -45.8 68.0 0.453 0.0 HOH
 2.624
 OD1
 O
5p9p 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 68.0 0.453 H -65.7 -45.8 68.0 0.453 0.0 HOH
 2.609
 OD1
 O
5p9q 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 72.0 0.48 H -65.9 -43.8 72.0 0.48 0.0 HOH
 2.433
 OD1
 O
5p9r 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 64.0 0.427 H -64.9 -45.9 64.0 0.427 0.0 HOH
 3.030
 OD2
 O
ASP B:178 B:178 74.0 0.493 H -60.6 -46.0 NA NA NA
5p9s 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 77.0 0.513 H -66.8 -40.7 77.0 0.513 0.0 HOH
 2.746
 OD2
 O
5p9t 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 74.0 0.493 H -64.8 -43.2 74.0 0.493 0.0 HOH
 2.701
 OD1
 O
5p9u 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 73.0 0.487 H -65.1 -47.5 73.0 0.487 0.0 HOH
 2.748
 OD1
 O
5p9v 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 75.0 0.5 H -69.0 -43.5 75.0 0.5 0.0 HOH
 2.630
 OD2
 O
5p9x 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 76.0 0.507 H -64.9 -43.4 76.0 0.507 0.0 HOH
 2.513
 OD2
 O
5p9y 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 77.0 0.513 H -67.0 -43.5 77.0 0.513 0.0 HOH
 2.551
 OD1
 O
5p9z 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 79.0 0.527 H -73.8 -42.7 79.0 0.527 0.0 HOH
 2.713
 OD1
 O
5pa0 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 77.0 0.513 H -67.5 -45.1 77.0 0.513 0.0 CXS
HOH
 9.858
2.751
 O
OD1
 H72
O
5pa2 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 73.0 0.487 H -64.1 -47.7 73.0 0.487 0.0 HOH
 2.604
 OD2
 O
5pa3 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 70.0 0.467 H -65.6 -46.2 70.0 0.467 0.0 HOH
 2.482
 OD1
 O
5pa4 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 76.0 0.507 H -69.4 -43.1 76.0 0.507 0.0 HOH
 2.628
 OD1
 O
5pa5 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 72.0 0.48 H -65.9 -43.8 72.0 0.48 0.0 HOH
 2.433
 OD1
 O
5pa6 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 77.0 0.513 H -67.0 -45.7 77.0 0.513 0.0 HOH
 2.660
 OD2
 O
5pa7 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ASP A:178 A:178 119.0 0.793 H -67.0 -41.3 119.0 0.793 0.0 HOH
 2.923
 N
 O
ASP B:178 B:178 118.0 0.787 H -69.8 -43.9 NA NA NA
5k09 1 P22734 82.03 7e-135 X-RAY
 2016-09-07 ASP A:177 A:178 123.0 0.82 H -56.3 -53.9 123.0 0.82 0.0 HOH
 4.560
 CB
 O
ASP B:177 B:178 123.0 0.82 H -50.2 -50.9 NA NA NA
ASP C:177 C:178 116.0 0.773 H -68.8 -37.7 NA NA NA
ASP D:177 D:178 117.0 0.78 H -72.2 -39.0 NA NA NA
ASP E:177 E:178 116.0 0.773 H -62.6 -48.0 NA NA NA
ASP F:177 F:178 124.0 0.827 H -63.5 -49.2 NA NA NA
ASP G:177 G:178 120.0 0.8 H -64.1 -44.9 NA NA NA
ASP H:177 H:178 116.0 0.773 H -57.9 -43.1 NA NA NA
ASP I:177 I:178 118.0 0.787 H -60.5 -54.1 NA NA NA
ASP J:177 J:178 122.0 0.813 H -73.8 -44.7 NA NA NA
ASP K:177 K:178 118.0 0.787 H -71.9 -45.7 NA NA NA
ASP L:177 L:178 119.0 0.793 H -63.9 -55.3 NA NA NA
ASP M:177 M:178 117.0 0.78 H -65.6 -45.5 NA NA NA
ASP N:177 N:178 120.0 0.8 H -70.3 -44.0 NA NA NA
ASP O:177 O:178 111.0 0.74 H -56.4 -54.2 NA NA NA
ASP P:177 P:178 125.0 0.833 H -71.3 -44.0 NA NA NA
ASP Q:177 Q:178 115.0 0.767 H -61.1 -46.5 NA NA NA
ASP R:177 R:178 125.0 0.833 H -54.9 -60.6 NA NA NA
ASP S:177 S:178 120.0 0.8 H -58.1 -48.3 NA NA NA
ASP T:177 T:178 121.0 0.807 H -62.6 -46.8 NA NA NA
ASP U:177 U:178 115.0 0.767 H -66.9 -41.7 NA NA NA
ASP V:177 V:178 118.0 0.787 H -57.3 -51.7 NA NA NA
ASP W:177 W:178 115.0 0.767 H -61.9 -59.2 NA NA NA
ASP X:177 X:178 116.0 0.773 H -72.8 -51.3 NA NA NA
5k0b 1 P22734 81.65 8e-135 X-RAY
 2016-09-07 ASP A:177 A:178 77.0 0.513 H -63.9 -43.4 77.0 0.513 0.0 PO4
HOH
 9.990
2.722
 OD1
OD2
 O2
O
ASP B:177 B:178 75.0 0.5 H -64.5 -37.4 NA NA NA
ASP C:177 C:178 116.0 0.773 H -70.5 -43.6 NA NA NA
ASP D:177 D:178 118.0 0.787 H -73.6 -39.8 NA NA NA
ASP E:177 E:178 115.0 0.767 H -68.8 -40.6 NA NA NA
ASP F:177 F:178 76.0 0.507 H -68.8 -43.0 NA NA NA
ASP G:177 G:178 76.0 0.507 H -68.1 -36.0 NA NA NA
ASP H:177 H:178 118.0 0.787 H -70.9 -39.3 NA NA NA
4p7f 1 O88587 81.19 1e-134 X-RAY
 2014-06-11 ASP A:178 A:221 91.0 0.607 H -71.9 -42.7 91.0 0.607 0.0 HOH
 2.516
 OD2
 O
5k0f 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 ASP A:177 A:178 75.0 0.5 H -66.2 -43.3 75.0 0.5 0.0 HOH
 2.642
 O
 O
ASP B:177 B:178 75.0 0.5 H -61.7 -45.3 NA NA NA
5k0g 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 ASP A:177 A:178 74.0 0.493 H -67.9 -44.2 74.0 0.493 0.0 HOH
 2.670
 O
 O
ASP B:177 B:178 78.0 0.52 H -65.1 -42.1 NA NA NA
5k0j 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 ASP A:177 A:178 73.0 0.487 H -67.6 -42.1 73.0 0.487 0.0 HOH
 2.548
 O
 O
ASP B:177 B:178 75.0 0.5 H -62.0 -46.1 NA NA NA
5k0n 1 P22734 81.94 4e-134 X-RAY
 2016-09-07 ASP A:177 A:178 73.0 0.487 H -58.9 -45.0 73.0 0.487 0.0 HOH
 2.442
 OD2
 O
ASP B:177 B:178 71.0 0.473 H -63.1 -41.1 NA NA NA
ASP C:177 C:178 76.0 0.507 H -65.7 -39.4 NA NA NA
ASP D:177 D:178 76.0 0.507 H -63.2 -40.9 NA NA NA
5k0l 1 P22734 81.94 4e-134 X-RAY
 2016-09-07 ASP A:177 A:178 72.0 0.48 H -59.8 -44.3 72.0 0.48 0.0 HOH
 2.542
 OD2
 O
ASP B:177 B:178 74.0 0.493 H -59.4 -44.4 NA NA NA
ASP C:177 C:178 76.0 0.507 H -72.7 -40.0 NA NA NA
ASP D:177 D:178 74.0 0.493 H -66.4 -40.8 NA NA NA
5k0c 1 P22734 82.33 5e-134 X-RAY
 2016-09-07 ASP A:177 A:178 72.0 0.48 H -65.7 -50.3 72.0 0.48 0.0 NHE
HOH
 7.766
2.544
 OD2
O
 O2
O
ASP B:177 B:178 74.0 0.493 H -62.9 -42.5 NA NA NA
5k0e 1 P22734 82.33 5e-134 X-RAY
 2016-09-07 ASP A:177 A:178 117.0 0.78 H -79.2 -35.2 117.0 0.78 0.0 HOH
 2.963
 O
 O
6aw5 1 ? 81.0 5e-134 X-RAY
 2018-09-12 ASP A:177 A:177 58.0 0.387 -91.7 92.1 58.0 0.387 0.0 HOH
 2.661
 OD2
 O
6aw6 1 ? 81.0 5e-134 X-RAY
 2018-09-12 ASP A:177 A:177 75.0 0.5 H -74.7 -47.4 75.0 0.5 0.0 HOH
 2.608
 OD2
 O
6aw9 1 ? 81.0 5e-134 X-RAY
 2018-09-12 ASP A:177 A:177 117.0 0.78 H -67.8 -37.9 117.0 0.78 0.0 HOH
 4.808
 N
 O
ASP B:177 B:177 67.0 0.447 H -65.4 -40.9 NA NA NA
ASP C:177 C:177 121.0 0.807 H -55.7 -40.0 NA NA NA
6aw4 1 ? 80.54 2e-133 X-RAY
 2018-09-12 ASP A:177 A:177 61.0 0.407 -93.0 94.9 61.0 0.407 0.0 HOH
 2.733
 OD2
 O
6aw7 1 ? 80.54 2e-133 X-RAY
 2018-09-12 ASP A:177 A:177 120.0 0.8 H -60.0 -48.5 120.0 0.8 0.0 HOH
 3.341
 CB
 O
ASP B:177 B:177 118.0 0.787 H -71.5 -41.5 NA NA NA
6aw8 1 ? 80.54 2e-133 X-RAY
 2018-09-12 ASP A:177 A:177 119.0 0.793 H -68.3 -47.8 119.0 0.793 0.0 HOH
 2.865
 OD1
 O
ASP B:177 B:177 71.0 0.473 H -72.2 -40.8 NA NA NA
ASP C:177 C:177 121.0 0.807 H -63.3 -44.4 NA NA NA
5k05 1 P22734 82.24 2e-133 X-RAY
 2016-09-07 ASP A:176 A:178 59.0 0.393 H -67.7 -42.9 59.0 0.393 0.0 HOH
 2.551
 OD2
 O
ASP B:176 B:178 117.0 0.78 H -58.6 -49.9 NA NA NA
1h1d 1 P22734 81.11 2e-133 X-RAY
 2003-07-17 ASP A:178 A:178 74.0 0.493 H -67.0 -43.6 74.0 0.493 0.0 HOH
 2.607
 OD2
 O
1jr4 1 P22734 81.11 2e-133 X-RAY
 2002-08-10 ASP A:178 A:178 68.0 0.453 H -53.8 -48.0 68.0 0.453 0.0 HOH
 2.673
 OD1
 O
1vid 1 P22734 81.11 2e-133 X-RAY
 1996-07-11 ASP A:178 A:178 76.0 0.507 H -62.5 -41.6 76.0 0.507 0.0 HOH
 3.007
 OD1
 O
2cl5 1 P22734 81.11 2e-133 X-RAY
 2006-06-28 ASP A:178 A:178 75.0 0.5 H -69.1 -38.9 75.0 0.5 0.0 HOH
 2.854
 O
 O
ASP B:178 B:178 70.0 0.467 H -64.4 -46.8 NA NA NA
3hvh 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 ASP A:178 A:221 75.0 0.5 H -65.5 -46.4 75.0 0.5 0.0 HOH
 2.548
 OD2
 O
3hvi 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 ASP A:178 A:221 73.0 0.487 H -68.8 -48.8 73.0 0.487 0.0 HOH
 2.612
 OD2
 O
3hvj 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 ASP A:178 A:221 68.0 0.453 H -65.3 -44.7 68.0 0.453 0.0 HOH
 2.583
 OD2
 O
ASP B:178 B:221 66.0 0.44 H -65.3 -44.7 NA NA NA
3hvk 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 ASP A:178 A:221 75.0 0.5 H -67.7 -45.6 75.0 0.5 0.0 HOH
 2.541
 OD2
 O
3nw9 1 P22734 81.11 2e-133 X-RAY
 2011-03-16 ASP A:178 A:178 76.0 0.507 H -71.4 -47.2 76.0 0.507 0.0 HOH
 2.461
 OD2
 O
3nwb 1 P22734 81.11 2e-133 X-RAY
 2011-08-03 ASP A:178 A:178 76.0 0.507 H -65.1 -45.8 76.0 0.507 0.0 HOH
 2.749
 OD1
 O
3s68 1 P22734 81.11 2e-133 X-RAY
 2012-02-01 ASP A:178 A:178 76.0 0.507 H -67.2 -46.0 76.0 0.507 0.0 HOH
 2.682
 OD1
 O
4p7g 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 ASP A:178 A:221 115.0 0.767 H -60.9 -50.1 115.0 0.767 0.0 HOH
 3.367
 CB
 O
ASP B:178 B:221 50.0 0.333 -55.5 113.9 NA NA NA
ASP C:178 C:221 51.0 0.34 -44.9 110.9 NA NA NA
ASP D:178 D:221 100.0 0.667 T -109.7 -46.3 NA NA NA
4p7j 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 ASP A:178 A:221 114.0 0.76 H -70.6 -43.9 114.0 0.76 0.0 HOH
 2.760
 O
 O
4p7k 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 ASP A:178 A:221 118.0 0.787 H -69.7 -40.0 118.0 0.787 0.0 HOH
 2.570
 H
 O
4pyl 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 ASP A:178 A:221 71.0 0.473 H -64.6 -45.7 71.0 0.473 0.0 HOH
 2.610
 OD1
 O
5lqc 1 P22734 81.11 2e-133 X-RAY
 2016-08-31 ASP A:178 A:178 76.0 0.507 H -68.5 -42.8 76.0 0.507 0.0 HOH
 2.441
 OD2
 O
5lqr 1 P22734 81.11 2e-133 X-RAY
 2016-10-05 ASP A:178 A:178 75.0 0.5 H -67.1 -44.1 75.0 0.5 0.0 HOH
 2.529
 OD2
 O
5lqu 1 P22734 81.11 2e-133 X-RAY
 2016-10-05 ASP A:178 A:178 72.0 0.48 H -71.2 -40.8 72.0 0.48 0.0 HOH
 2.430
 OD2
 O
ASP B:178 B:178 68.0 0.453 H -68.5 -41.8 NA NA NA
5p95 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:178 A:178 76.0 0.507 H -70.7 -45.9 76.0 0.507 0.0 HOH
 2.563
 OD2
 O
5p96 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:178 A:178 75.0 0.5 H -67.3 -44.4 75.0 0.5 0.0 HOH
 2.561
 OD2
 O
5p97 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:178 A:178 75.0 0.5 H -69.3 -45.6 75.0 0.5 0.0 HOH
 2.577
 OD2
 O
5p98 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:178 A:178 76.0 0.507 H -67.3 -46.3 76.0 0.507 0.0 HOH
 2.625
 OD2
 O
5p99 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:178 A:178 76.0 0.507 H -67.8 -47.8 76.0 0.507 0.0 HOH
 2.511
 OD2
 O
5p9a 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:178 A:178 74.0 0.493 H -68.9 -42.4 74.0 0.493 0.0 HOH
 2.584
 OD2
 O
5p9b 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:178 A:178 74.0 0.493 H -68.4 -47.9 74.0 0.493 0.0 HOH
 2.539
 OD2
 O
5p9c 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:178 A:178 74.0 0.493 H -73.4 -39.7 74.0 0.493 0.0 SO4
HOH
 8.268
2.507
 OD1
OD1
 O2
O
5p9d 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:178 A:178 77.0 0.513 H -71.1 -39.3 77.0 0.513 0.0 HOH
 2.494
 OD2
 O
5p9e 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ASP A:178 A:178 77.0 0.513 H -68.5 -44.6 77.0 0.513 0.0 HOH
 2.631
 OD2
 O
5p9w 1 P22734 81.11 2e-133 X-RAY
 2017-11-22 ASP A:178 A:178 75.0 0.5 H -71.4 -46.5 75.0 0.5 0.0 SO4
HOH
 8.032
2.563
 OD1
OD1
 O2
O
5pa1 1 P22734 81.11 2e-133 X-RAY
 2017-11-22 ASP A:178 A:178 79.0 0.527 H -71.5 -46.4 79.0 0.527 0.0 SO4
HOH
 9.621
2.592
 OD1
OD2
 O1
O
2zlb 1 P22734 81.11 3e-133 X-RAY
 2008-10-07 ASP A:180 A:178 113.0 0.753 H -78.5 -45.9 113.0 0.753 0.0 HOH
 2.764
 O
 O
2zth 1 P22734 81.11 3e-133 X-RAY
 2009-01-13 ASP A:180 A:178 113.0 0.753 H -64.5 -59.6 113.0 0.753 0.0 HOH
 3.174
 N
 O
2zvj 1 P22734 81.11 3e-133 X-RAY
 2009-01-06 ASP A:180 A:178 74.0 0.493 H -71.4 -43.4 74.0 0.493 0.0 HOH
 2.502
 OD2
 O
3a7d 1 P22734 81.11 3e-133 X-RAY
 2010-09-15 ASP A:180 A:178 70.0 0.467 H -76.1 -37.4 70.0 0.467 0.0 HOH
 2.507
 OD2
 O
6gy1 1 P22734 81.11 3e-133 X-RAY
 2018-10-10 ASP A:180 A:178 75.0 0.5 H -64.2 -45.7 75.0 0.5 0.0 HOH
 2.453
 OD1
 O
6lfe 1 P22734 81.11 3e-133 X-RAY
 2020-03-04 ASP A:180 A:178 75.0 0.5 H -71.2 -44.2 75.0 0.5 0.0 HOH
 2.646
 OD2
 O
5k01 1 P22734 81.78 1e-132 X-RAY
 2016-09-07 ASP A:176 A:178 121.0 0.807 H -69.9 -41.5 121.0 0.807 0.0 HOH
 2.543
 OD1
 O
5k03 1 P22734 81.78 1e-132 X-RAY
 2016-09-07 ASP A:176 A:178 122.0 0.813 H -67.7 -40.6 122.0 0.813 0.0 HOH
 2.633
 O
 O
4p58 1 O88587 81.6 2e-131 X-RAY
 2014-06-25 ASP A:175 A:221 111.0 0.74 H -72.7 -50.1 111.0 0.74 0.0 HOH
 3.277
 OD2
 O
5fhq 1 P22734 81.22 9e-131 X-RAY
 2016-02-03 ASP A:176 A:178 76.0 0.507 H -66.3 -48.2 76.0 0.507 0.0 HOH
 2.617
 OD2
 O
5lqa 1 P22734 81.22 9e-131 X-RAY
 2016-10-05 ASP A:176 A:178 77.0 0.513 H -63.9 -47.9 77.0 0.513 0.0 HOH
 2.562
 OD2
 O
5fhr 1 P22734 80.75 2e-129 X-RAY
 2016-02-03 ASP A:176 A:221 121.0 0.807 H -64.8 -45.2 121.0 0.807 0.0 HOH
 2.103
 OD1
 O
ASP B:176 B:221 119.0 0.793 H -66.2 -42.9 119.0 0.793 0.0 HOH
 2.356
 OD2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21964-f1 1 P21964 100.0 0.0 ASP A:228 A:228 113.0 0.753 H -69.1 -39.2