Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 19956143 . C A CCDS13770.1:NM_000754.3:c.700Cgc>Agc_NP_000745.1:p.234R>S Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4pyi 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 ARG A:184 A:234 119.0 0.529 H -68.1 -48.5 119.0 0.529 0.0 NA
HOH
 2.521
2.051
 O
HH12
 NA
O
4pyj 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 ARG A:184 A:234 126.0 0.56 H -68.6 -46.5 126.0 0.56 0.0 NA
HOH
 2.497
2.868
 O
NH1
 NA
O
4pyk 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 ARG A:184 A:234 123.0 0.547 H -69.6 -56.1 123.0 0.547 0.0 NA
HOH
 2.241
3.107
 O
NH1
 NA
O
5lsa 1 P21964 100.0 3e-165 X-RAY
 2016-09-07 ARG A:184 A:234 123.0 0.547 H -69.6 -45.2 123.0 0.547 0.0 HOH
 2.466
 O
 O
6i3c 1 P21964 99.1 4e-164 X-RAY
 2019-09-18 ARG A:195 A:184 127.0 0.564 H -72.2 -35.4 127.0 0.564 0.0 HOH
 2.825
 O
 O
6i3d 1 P21964 99.1 4e-164 X-RAY
 2019-09-18 ARG A:195 A:184 125.0 0.556 H -71.8 -29.5 125.0 0.556 0.0 HOH
 3.052
 O
 O
ARG B:195 B:184 126.0 0.56 H -71.9 -28.3 NA NA NA
4xuc 1 P21964 99.54 1e-161 X-RAY
 2015-04-15 ARG A:187 A:234 126.0 0.56 H -70.3 -39.7 126.0 0.56 0.0 HOH
 2.711
 O
 O
4xud 1 P21964 99.54 1e-161 X-RAY
 2015-04-15 ARG A:187 A:234 130.0 0.578 H -70.1 -33.8 130.0 0.578 0.0 HOH
 2.929
 O
 O
4xue 1 P21964 100.0 1e-159 X-RAY
 2015-04-15 ARG A:184 B:234 125.0 0.556 H -70.1 -34.6 125.0 0.556 0.0 HOH
 2.930
 NH2
 O
ARG B:184 A:234 125.0 0.556 H -70.7 -35.4 NA NA NA
3a7e 1 P21964 100.0 1e-159 X-RAY
 2010-09-15 ARG A:186 A:184 134.0 0.596 H -63.2 -37.6 134.0 0.596 0.0 HOH
 2.903
 NH1
 O
3bwm 1 P21964 100.0 2e-159 X-RAY
 2008-06-03 ARG A:183 A:184 125.0 0.556 H -72.6 -37.7 125.0 0.556 0.0 K
HOH
 2.909
3.297
 O
NH2
 K
O
3bwy 1 Q6ICE6 99.53 5e-159 X-RAY
 2008-06-03 ARG A:183 A:184 124.0 0.551 H -68.7 -47.1 124.0 0.551 0.0 HOH
 2.503
 O
 O
3nwe 1 P22734 82.03 6e-135 X-RAY
 2011-08-03 ARG A:184 A:184 128.0 0.569 H -67.8 -25.5 128.0 0.569 0.0 HOH
 2.017
 HH22
 O
3oe4 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ARG A:184 A:184 137.0 0.609 H -67.0 -27.0 137.0 0.609 0.0 HOH
 2.877
 NH2
 O
3oe5 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ARG A:184 A:184 137.0 0.609 H -70.3 -25.3 137.0 0.609 0.0 HOH
 2.878
 NH2
 O
3ozr 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ARG A:184 A:184 126.0 0.56 H -67.4 -32.6 126.0 0.56 0.0 HOH
 2.965
 O
 O
3ozs 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ARG A:184 A:184 135.0 0.6 H -69.4 -29.2 135.0 0.6 0.0 HOH
 3.042
 O
 O
3ozt 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 ARG A:184 A:184 138.0 0.613 H -70.1 -30.6 138.0 0.613 0.0 HOH
 2.773
 NH2
 O
3r6t 1 P22734 82.03 6e-135 X-RAY
 2012-02-01 ARG A:184 A:227 127.0 0.564 H -67.4 -27.3 127.0 0.564 0.0 DTD
HOH
 9.573
2.877
 N
NH2
 S1
O
3u81 1 P22734 82.03 6e-135 X-RAY
 2012-02-01 ARG A:184 A:184 124.0 0.551 H -66.8 -41.3 124.0 0.551 0.0 K
HOH
 2.655
2.092
 O
HH11
 K
O
4pym 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ARG A:184 A:227 125.0 0.556 H -67.7 -33.9 125.0 0.556 0.0 K
HOH
 2.814
2.109
 O
HH22
 K
O
4pyn 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ARG A:184 A:227 127.0 0.564 H -69.1 -33.6 127.0 0.564 0.0 K
HOH
 2.795
2.120
 O
HH12
 K
O
4pyo 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ARG A:184 A:227 127.0 0.564 H -68.8 -34.4 127.0 0.564 0.0 K
HOH
 2.628
3.238
 O
NH2
 K
O
ARG B:184 B:227 122.0 0.542 H -70.0 -46.4 NA NA NA
4pyq 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 ARG A:184 A:227 120.0 0.533 H -75.7 -39.9 29.0 0.129 0.404 B:P22734:0.404
 NA
HOH
 2.507
2.242
 O
HH22
 NA
O
ARG B:184 B:227 117.0 0.52 H -71.0 -51.7 25.0 0.111 0.409 A:P22734:0.409
 NA
HOH
 2.441
2.338
 O
HH22
 NA
O
5lqj 1 P22734 82.03 6e-135 X-RAY
 2016-09-28 ARG A:184 A:184 126.0 0.56 H -63.8 -37.2 126.0 0.56 0.0 NA
72N
HOH
 2.670
7.056
2.871
 O
C
NH1
 NA
C15
O
ARG B:184 B:184 132.0 0.587 H -65.5 -40.6 NA NA NA
ARG C:184 C:184 126.0 0.56 H -70.6 -36.5 NA NA NA
ARG D:184 D:184 133.0 0.591 H -65.9 -38.8 NA NA NA
5lqk 1 P22734 82.03 6e-135 X-RAY
 2016-08-31 ARG A:184 A:184 131.0 0.582 H -74.4 -24.1 131.0 0.582 0.0 HOH
 3.105
 O
 O
5lqn 1 P22734 82.03 6e-135 X-RAY
 2016-10-05 ARG A:184 A:184 128.0 0.569 H -75.8 -20.2 128.0 0.569 0.0 HOH
 2.818
 O
 O
5lr6 1 P22734 82.03 6e-135 X-RAY
 2016-08-31 ARG A:184 A:184 124.0 0.551 H -66.1 -39.6 124.0 0.551 0.0 HOH
 2.423
 O
 O
ARG B:184 B:184 125.0 0.556 H -70.1 -27.4 NA NA NA
ARG C:184 C:184 120.0 0.533 H -69.4 -34.3 NA NA NA
ARG D:184 D:184 126.0 0.56 H -70.5 -29.3 NA NA NA
5p8w 1 P22734 82.03 6e-135 X-RAY
 2016-09-07 ARG A:184 A:184 131.0 0.582 H -69.5 -40.1 125.0 0.556 0.026 B:P22734:0.027
 NA
HOH
 2.555
2.851
 O
NH2
 NA
O
ARG B:184 B:184 129.0 0.573 H -70.5 -44.1 68.0 0.302 0.271 A:P22734:0.036
C:P22734:0.236
 NA
DTT
HOH
 2.513
8.857
2.799
 O
NH1
NH2
 NA
C4
O
ARG C:184 C:184 126.0 0.56 H -74.0 -38.6 126.0 0.56 0.0 NA
HOH
 2.593
3.005
 O
NH2
 NA
O
5p8x 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ARG A:184 A:184 127.0 0.564 H -69.6 -23.9 127.0 0.564 0.0 HOH
 2.845
 NH1
 O
5p8y 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ARG A:184 A:184 127.0 0.564 H -64.9 -30.0 127.0 0.564 0.0 HOH
 2.909
 NH1
 O
5p8z 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ARG A:184 A:184 125.0 0.556 H -67.0 -25.1 125.0 0.556 0.0 HOH
 2.840
 NH1
 O
5p90 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ARG A:184 A:184 128.0 0.569 H -70.2 -25.1 128.0 0.569 0.0 HOH
 2.879
 NH1
 O
5p91 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ARG A:184 A:184 126.0 0.56 H -68.4 -25.5 126.0 0.56 0.0 HOH
 2.841
 NH1
 O
5p92 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ARG A:184 A:184 124.0 0.551 H -69.5 -29.2 124.0 0.551 0.0 HOH
 2.864
 NH2
 O
5p93 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ARG A:184 A:184 124.0 0.551 H -69.4 -25.0 124.0 0.551 0.0 HOH
 2.811
 NH1
 O
5p94 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 ARG A:184 A:184 126.0 0.56 H -69.5 -24.1 126.0 0.56 0.0 HOH
 2.898
 NH2
 O
5p9n 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 124.0 0.551 H -69.5 -24.8 124.0 0.551 0.0 HOH
 2.879
 NH2
 O
5p9o 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 125.0 0.556 H -74.7 -21.6 125.0 0.556 0.0 HOH
 2.849
 NH2
 O
5p9p 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 127.0 0.564 H -73.0 -22.2 127.0 0.564 0.0 HOH
 2.880
 NH2
 O
5p9q 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 128.0 0.569 H -70.1 -26.1 128.0 0.569 0.0 HOH
 2.888
 NH2
 O
5p9r 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 130.0 0.578 H -71.9 -27.6 130.0 0.578 0.0 HOH
 2.974
 NH2
 O
ARG B:184 B:184 131.0 0.582 H -72.8 -21.5 NA NA NA
5p9s 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 129.0 0.573 H -64.2 -31.7 129.0 0.573 0.0 HOH
 2.682
 O
 O
5p9t 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 126.0 0.56 H -65.8 -29.0 126.0 0.56 0.0 HOH
 2.835
 NH1
 O
5p9u 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 134.0 0.596 H -68.8 -32.2 134.0 0.596 0.0 HOH
 2.876
 O
 O
5p9v 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 124.0 0.551 H -72.3 -24.0 124.0 0.551 0.0 CXS
HOH
 9.403
2.878
 N
NH1
 C8
O
5p9x 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 124.0 0.551 H -67.8 -27.5 124.0 0.551 0.0 HOH
 2.859
 NH2
 O
5p9y 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 125.0 0.556 H -66.8 -25.4 125.0 0.556 0.0 NHE
HOH
 9.601
2.920
 N
NH2
 C5'
O
5p9z 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 129.0 0.573 H -67.1 -26.2 129.0 0.573 0.0 HOH
 2.806
 NH2
 O
5pa0 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 130.0 0.578 H -70.1 -23.8 130.0 0.578 0.0 CXS
HOH
 8.681
2.037
 N
HH11
 H81
O
5pa2 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 125.0 0.556 H -73.2 -22.9 125.0 0.556 0.0 HOH
 2.812
 NH1
 O
5pa3 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 123.0 0.547 H -66.4 -36.3 123.0 0.547 0.0 K
HOH
 2.813
2.872
 O
NH2
 K
O
5pa4 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 126.0 0.56 H -72.2 -30.0 126.0 0.56 0.0 HOH
 2.855
 NH2
 O
5pa5 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 128.0 0.569 H -70.1 -26.1 128.0 0.569 0.0 HOH
 2.888
 NH2
 O
5pa6 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 130.0 0.578 H -68.7 -26.7 130.0 0.578 0.0 HOH
 2.748
 NH1
 O
5pa7 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 ARG A:184 A:184 124.0 0.551 H -65.1 -36.1 124.0 0.551 0.0 NA
HOH
 2.860
3.358
 O
NE
 NA
O
ARG B:184 B:184 131.0 0.582 H -69.4 -36.5 NA NA NA
5k09 1 P22734 82.03 7e-135 X-RAY
 2016-09-07 ARG A:183 A:184 128.0 0.569 H -71.2 -32.8 128.0 0.569 0.0 K
HOH
 2.969
3.404
 O
NE
 K
O
ARG B:183 B:184 129.0 0.573 H -70.7 -23.9 NA NA NA
ARG C:183 C:184 131.0 0.582 H -75.8 -31.8 NA NA NA
ARG D:183 D:184 127.0 0.564 H -71.6 -23.1 NA NA NA
ARG E:183 E:184 131.0 0.582 H -74.3 -35.9 NA NA NA
ARG F:183 F:184 130.0 0.578 H -66.2 -34.4 NA NA NA
ARG G:183 G:184 128.0 0.569 H -75.7 -31.7 NA NA NA
ARG H:183 H:184 126.0 0.56 H -79.7 -31.5 NA NA NA
ARG I:183 I:184 129.0 0.573 H -72.1 -35.1 NA NA NA
ARG J:183 J:184 125.0 0.556 H -68.9 -33.9 NA NA NA
ARG K:183 K:184 127.0 0.564 H -82.5 -31.5 NA NA NA
ARG L:183 L:184 129.0 0.573 H -67.6 -26.4 NA NA NA
ARG M:183 M:184 124.0 0.551 H -73.1 -40.8 NA NA NA
ARG N:183 N:184 128.0 0.569 H -72.4 -29.9 NA NA NA
ARG O:183 O:184 127.0 0.564 H -76.9 -32.9 NA NA NA
ARG P:183 P:184 129.0 0.573 H -76.8 -35.1 NA NA NA
ARG Q:183 Q:184 119.0 0.529 H -64.0 -57.3 NA NA NA
ARG R:183 R:184 124.0 0.551 H -76.9 -27.4 NA NA NA
ARG S:183 S:184 129.0 0.573 H -81.7 -17.4 NA NA NA
ARG T:183 T:184 128.0 0.569 H -80.4 -27.9 NA NA NA
ARG U:183 U:184 128.0 0.569 H -73.8 -29.7 NA NA NA
ARG V:183 V:184 127.0 0.564 H -88.1 -20.0 NA NA NA
ARG W:183 W:184 126.0 0.56 H -80.5 -28.3 NA NA NA
ARG X:183 X:184 128.0 0.569 H -61.4 -40.9 NA NA NA
5k0b 1 P22734 81.65 8e-135 X-RAY
 2016-09-07 ARG A:183 A:184 133.0 0.591 H -72.5 -37.3 133.0 0.591 0.0 PO4
K
HOH
 7.583
2.761
2.860
 O
O
NH1
 O1
K
O
ARG B:183 B:184 131.0 0.582 H -72.2 -34.2 NA NA NA
ARG C:183 C:184 133.0 0.591 H -65.6 -33.3 NA NA NA
ARG D:183 D:184 132.0 0.587 H -67.8 -45.1 NA NA NA
ARG E:183 E:184 132.0 0.587 H -80.1 -26.6 NA NA NA
ARG F:183 F:184 131.0 0.582 H -72.5 -37.8 NA NA NA
ARG G:183 G:184 131.0 0.582 H -70.9 -34.3 NA NA NA
ARG H:183 H:184 131.0 0.582 H -73.0 -34.5 NA NA NA
4p7f 1 O88587 81.19 1e-134 X-RAY
 2014-06-11 ARG A:184 A:227 121.0 0.538 H -74.2 -42.2 121.0 0.538 0.0 NA
PI
HOH
 2.536
6.449
1.970
 O
HH22
HH12
 NA
O1
O
5k0f 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 ARG A:183 A:184 122.0 0.542 H -69.6 -39.1 122.0 0.542 0.0 NA
HOH
 2.645
3.035
 O
NH2
 NA
O
ARG B:183 B:184 122.0 0.542 H -71.6 -38.0 NA NA NA
5k0g 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 ARG A:183 A:184 122.0 0.542 H -69.6 -36.9 122.0 0.542 0.0 NA
HOH
 2.667
2.985
 O
NH2
 NA
O
ARG B:183 B:184 123.0 0.547 H -71.2 -36.9 NA NA NA
5k0j 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 ARG A:183 A:184 123.0 0.547 H -70.1 -40.5 123.0 0.547 0.0 NA
HOH
 2.641
2.932
 O
O
 NA
O
ARG B:183 B:184 123.0 0.547 H -71.5 -36.9 NA NA NA
5k0n 1 P22734 81.94 4e-134 X-RAY
 2016-09-07 ARG A:183 A:184 124.0 0.551 H -72.2 -38.6 124.0 0.551 0.0 K
HOH
 2.622
2.867
 O
NH2
 K
O
ARG B:183 B:184 125.0 0.556 H -70.4 -36.6 NA NA NA
ARG C:183 C:184 121.0 0.538 H -75.9 -34.4 NA NA NA
ARG D:183 D:184 125.0 0.556 H -68.9 -39.9 NA NA NA
5k0l 1 P22734 81.94 4e-134 X-RAY
 2016-09-07 ARG A:183 A:184 121.0 0.538 H -72.0 -36.5 121.0 0.538 0.0 K
HOH
 2.707
3.001
 O
NH2
 K
O
ARG B:183 B:184 126.0 0.56 H -74.2 -33.8 NA NA NA
ARG C:183 C:184 121.0 0.538 H -70.2 -35.8 NA NA NA
ARG D:183 D:184 123.0 0.547 H -69.3 -41.7 NA NA NA
5k0c 1 P22734 82.33 5e-134 X-RAY
 2016-09-07 ARG A:183 A:184 122.0 0.542 H -68.7 -36.5 122.0 0.542 0.0 NA
HOH
 2.711
3.231
 O
NH2
 NA
O
ARG B:183 B:184 123.0 0.547 H -72.3 -38.5 NA NA NA
5k0e 1 P22734 82.33 5e-134 X-RAY
 2016-09-07 ARG A:183 A:184 125.0 0.556 H -69.3 -33.6 125.0 0.556 0.0 NA
HOH
 2.806
3.256
 O
NH2
 NA
O
6aw5 1 ? 81.0 5e-134 X-RAY
 2018-09-12 ARG A:183 A:183 127.0 0.564 H -70.0 -47.6 127.0 0.564 0.0 NA
HOH
 2.491
2.844
 O
NH2
 NA
O
6aw6 1 ? 81.0 5e-134 X-RAY
 2018-09-12 ARG A:183 A:183 128.0 0.569 H -75.3 -31.6 128.0 0.569 0.0 SO4
HOH
 7.235
2.805
 NH2
O
 O2
O
6aw9 1 ? 81.0 5e-134 X-RAY
 2018-09-12 ARG A:183 A:183 131.0 0.582 H -65.8 -36.3 131.0 0.582 0.0 HOH
 2.583
 O
 O
ARG B:183 B:183 130.0 0.578 H -67.6 -44.7 NA NA NA
ARG C:183 C:183 135.0 0.6 H -68.8 -47.2 NA NA NA
6aw4 1 ? 80.54 2e-133 X-RAY
 2018-09-12 ARG A:183 A:183 128.0 0.569 H -69.8 -44.5 128.0 0.569 0.0 NA
PO4
HOH
 2.468
7.021
2.834
 O
NH2
NH1
 NA
O1
O
6aw7 1 ? 80.54 2e-133 X-RAY
 2018-09-12 ARG A:183 A:183 130.0 0.578 H -64.2 -49.2 130.0 0.578 0.0 HOH
 2.527
 O
 O
ARG B:183 B:183 130.0 0.578 H -69.5 -42.1 NA NA NA
6aw8 1 ? 80.54 2e-133 X-RAY
 2018-09-12 ARG A:183 A:183 129.0 0.573 H -68.5 -51.5 129.0 0.573 0.0 HOH
 2.373
 O
 O
ARG B:183 B:183 131.0 0.582 H -68.5 -41.1 NA NA NA
ARG C:183 C:183 139.0 0.618 H -74.7 -35.2 NA NA NA
5k05 1 P22734 82.24 2e-133 X-RAY
 2016-09-07 ARG A:182 A:184 123.0 0.547 H -75.9 -29.1 123.0 0.547 0.0 HOH
 2.588
 NH1
 O
ARG B:182 B:184 129.0 0.573 H -71.6 -25.6 NA NA NA
1h1d 1 P22734 81.11 2e-133 X-RAY
 2003-07-17 ARG A:184 A:184 132.0 0.587 H -71.7 -25.4 132.0 0.587 0.0 HOH
 2.985
 O
 O
1jr4 1 P22734 81.11 2e-133 X-RAY
 2002-08-10 ARG A:184 A:184 126.0 0.56 H -74.5 -22.6 126.0 0.56 0.0 HOH
 3.078
 NE
 O
1vid 1 P22734 81.11 2e-133 X-RAY
 1996-07-11 ARG A:184 A:184 133.0 0.591 H -66.9 -29.1 133.0 0.591 0.0 HOH
 3.007
 O
 O
2cl5 1 P22734 81.11 2e-133 X-RAY
 2006-06-28 ARG A:184 A:184 139.0 0.618 H -75.4 -13.2 139.0 0.618 0.0 HOH
 2.830
 NH2
 O
ARG B:184 B:184 127.0 0.564 H -71.7 -23.9 NA NA NA
3hvh 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 ARG A:184 A:227 127.0 0.564 H -67.5 -33.5 127.0 0.564 0.0 CXS
CL
HOH
 9.476
2.872
2.705
 N
O
O
 C8
CL
O
3hvi 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 ARG A:184 A:227 124.0 0.551 H -65.2 -37.3 124.0 0.551 0.0 NA
HOH
 2.797
2.846
 O
NH1
 NA
O
3hvj 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 ARG A:184 A:227 128.0 0.569 H -73.4 -33.5 128.0 0.569 0.0 HOH
 2.938
 NH2
 O
ARG B:184 B:227 126.0 0.56 H -74.5 -42.0 NA NA NA
3hvk 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 ARG A:184 A:227 128.0 0.569 H -68.1 -24.5 128.0 0.569 0.0 HOH
 2.914
 NH1
 O
3nw9 1 P22734 81.11 2e-133 X-RAY
 2011-03-16 ARG A:184 A:184 130.0 0.578 H -66.6 -27.9 130.0 0.578 0.0 CL
HOH
 4.530
2.977
 O
NH2
 CL
O
3nwb 1 P22734 81.11 2e-133 X-RAY
 2011-08-03 ARG A:184 A:184 130.0 0.578 H -69.9 -24.9 130.0 0.578 0.0 HOH
 2.032
 HH22
 O
3s68 1 P22734 81.11 2e-133 X-RAY
 2012-02-01 ARG A:184 A:184 130.0 0.578 H -70.5 -27.0 130.0 0.578 0.0 HOH
 2.322
 HH11
 O
4p7g 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 ARG A:184 A:227 125.0 0.556 H -69.7 -44.2 125.0 0.556 0.0 K
HOH
 2.686
7.509
 O
NH1
 K
O
ARG B:184 B:227 127.0 0.564 H -79.2 -38.3 NA NA NA
ARG C:184 C:227 126.0 0.56 H -82.9 -46.1 NA NA NA
ARG D:184 D:227 121.0 0.538 H -78.1 -50.1 NA NA NA
4p7j 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 ARG A:184 A:227 125.0 0.556 H -67.6 -43.9 125.0 0.556 0.0 K
HOH
 2.574
2.991
 O
NH1
 K
O
4p7k 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 ARG A:184 A:227 127.0 0.564 H -67.7 -33.7 127.0 0.564 0.0 K
HOH
 2.785
2.072
 O
HH11
 K
O
4pyl 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 ARG A:184 A:227 125.0 0.556 H -65.0 -38.4 125.0 0.556 0.0 HOH
 2.745
 O
 O
5lqc 1 P22734 81.11 2e-133 X-RAY
 2016-08-31 ARG A:184 A:184 135.0 0.6 H -70.4 -27.7 128.0 0.569 0.031 A:P22734:0.031
 HOH
 2.916
 O
 O
5lqr 1 P22734 81.11 2e-133 X-RAY
 2016-10-05 ARG A:184 A:184 128.0 0.569 H -65.0 -26.6 128.0 0.569 0.0 HOH
 2.805
 NH2
 O
5lqu 1 P22734 81.11 2e-133 X-RAY
 2016-10-05 ARG A:184 A:184 129.0 0.573 H -75.0 -34.6 129.0 0.573 0.0 HOH
 2.655
 NH1
 O
ARG B:184 B:184 127.0 0.564 H -72.8 -43.2 NA NA NA
5p95 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:184 A:184 127.0 0.564 H -70.5 -22.7 127.0 0.564 0.0 HOH
 2.870
 NH1
 O
5p96 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:184 A:184 124.0 0.551 H -69.3 -24.7 124.0 0.551 0.0 HOH
 2.853
 O
 O
5p97 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:184 A:184 127.0 0.564 H -69.8 -25.1 127.0 0.564 0.0 HOH
 2.827
 O
 O
5p98 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:184 A:184 127.0 0.564 H -70.2 -23.7 127.0 0.564 0.0 HOH
 2.882
 NH2
 O
5p99 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:184 A:184 129.0 0.573 H -70.5 -23.4 129.0 0.573 0.0 HOH
 2.888
 NH1
 O
5p9a 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:184 A:184 131.0 0.582 H -66.3 -29.3 131.0 0.582 0.0 HOH
 3.002
 NH2
 O
5p9b 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:184 A:184 128.0 0.569 H -70.7 -24.4 128.0 0.569 0.0 NHE
HOH
 9.480
2.921
 N
NH2
 C3'
O
5p9c 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:184 A:184 130.0 0.578 H -68.0 -31.0 130.0 0.578 0.0 HOH
 2.829
 O
 O
5p9d 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:184 A:184 128.0 0.569 H -68.0 -25.2 128.0 0.569 0.0 HOH
 2.930
 NH2
 O
5p9e 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 ARG A:184 A:184 128.0 0.569 H -66.9 -27.5 128.0 0.569 0.0 HOH
 2.852
 NH2
 O
5p9w 1 P22734 81.11 2e-133 X-RAY
 2017-11-22 ARG A:184 A:184 128.0 0.569 H -68.0 -26.2 128.0 0.569 0.0 HOH
 2.885
 NH2
 O
5pa1 1 P22734 81.11 2e-133 X-RAY
 2017-11-22 ARG A:184 A:184 128.0 0.569 H -68.3 -25.8 128.0 0.569 0.0 HOH
 2.853
 NH1
 O
2zlb 1 P22734 81.11 3e-133 X-RAY
 2008-10-07 ARG A:186 A:184 119.0 0.529 H -67.7 -55.4 119.0 0.529 0.0 HOH
 2.368
 O
 O
2zth 1 P22734 81.11 3e-133 X-RAY
 2009-01-13 ARG A:186 A:184 134.0 0.596 H -77.1 -31.8 134.0 0.596 0.0 HOH
 6.437
 NH1
 O
2zvj 1 P22734 81.11 3e-133 X-RAY
 2009-01-06 ARG A:186 A:184 122.0 0.542 H -59.6 -51.9 122.0 0.542 0.0 HOH
 2.375
 O
 O
3a7d 1 P22734 81.11 3e-133 X-RAY
 2010-09-15 ARG A:186 A:184 122.0 0.542 H -64.9 -47.6 122.0 0.542 0.0 HOH
 2.588
 O
 O
6gy1 1 P22734 81.11 3e-133 X-RAY
 2018-10-10 ARG A:186 A:184 131.0 0.582 H -63.3 -31.3 131.0 0.582 0.0 HOH
 2.758
 O
 O
6lfe 1 P22734 81.11 3e-133 X-RAY
 2020-03-04 ARG A:186 A:184 128.0 0.569 H -68.4 -30.7 128.0 0.569 0.0 PEG
HOH
 2.679
2.958
 NH2
O
 O2
O
5k01 1 P22734 81.78 1e-132 X-RAY
 2016-09-07 ARG A:182 A:184 127.0 0.564 H -71.0 -33.0 127.0 0.564 0.0 K
HOH
 2.810
2.082
 O
HH11
 K
O
5k03 1 P22734 81.78 1e-132 X-RAY
 2016-09-07 ARG A:182 A:184 129.0 0.573 H -70.0 -28.7 129.0 0.573 0.0 K
HOH
 2.838
2.808
 O
NH2
 K
O
4p58 1 O88587 81.6 2e-131 X-RAY
 2014-06-25 ARG A:181 A:227 126.0 0.56 H -69.5 -50.7 126.0 0.56 0.0 HOH
 2.542
 O
 O
5fhq 1 P22734 81.22 9e-131 X-RAY
 2016-02-03 ARG A:182 A:184 133.0 0.591 H -65.7 -38.4 133.0 0.591 0.0 HOH
 2.187
 HH11
 O
5lqa 1 P22734 81.22 9e-131 X-RAY
 2016-10-05 ARG A:182 A:184 128.0 0.569 H -65.0 -28.6 128.0 0.569 0.0 HOH
 2.890
 NH2
 O
5fhr 1 P22734 80.75 2e-129 X-RAY
 2016-02-03 ARG A:182 A:227 134.0 0.596 H -70.0 -37.9 126.0 0.56 0.036 B:P22734:0.036
 HOH
 2.896
 O
 O
ARG B:182 B:227 130.0 0.578 H -72.3 -35.2 117.0 0.52 0.058 A:P22734:0.058
 HOH
 2.636
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21964-f1 1 P21964 100.0 0.0 ARG A:234 A:234 124.0 0.551 H -80.7 -26.8