Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 19956201 . T A CCDS13770.1:NM_000754.3:c.758gTg>gAg_NP_000745.1:p.253V>E Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4pyi 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 VAL A:203 A:253 65.0 0.419 E -83.6 108.9 65.0 0.419 0.0 HOH
 2.727
 HG11
 O
4pyj 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 VAL A:203 A:253 54.0 0.348 -142.1 170.5 54.0 0.348 0.0 MG
HOH
 6.940
5.225
 CG1
N
 MG
O
4pyk 1 P21964 100.0 3e-165 X-RAY
 2014-06-11 VAL A:203 A:253 54.0 0.348 -142.3 171.2 54.0 0.348 0.0 MG
HOH
 6.758
5.963
 CG1
CG1
 MG
O
5lsa 1 P21964 100.0 3e-165 X-RAY
 2016-09-07 VAL A:203 A:253 79.0 0.51 S -57.5 136.6 79.0 0.51 0.0 CL
DNC
HOH
 9.493
7.576
3.551
 O
CG1
CG1
 CL
O6
O
6i3c 1 P21964 99.1 4e-164 X-RAY
 2019-09-18 VAL A:214 A:203 79.0 0.51 S -56.1 138.8 79.0 0.51 0.0 DNC
HOH
 7.635
3.638
 CG1
CG1
 O6
O
6i3d 1 P21964 99.1 4e-164 X-RAY
 2019-09-18 VAL A:214 A:203 68.0 0.439 S -128.7 136.5 68.0 0.439 0.0 DNC
HOH
 8.051
3.663
 CG1
CA
 O6
O
VAL B:214 B:203 80.0 0.516 S -83.2 148.9 NA NA NA
4xuc 1 P21964 99.54 1e-161 X-RAY
 2015-04-15 VAL A:206 A:253 73.0 0.471 S -70.8 133.7 73.0 0.471 0.0 43G
MES
HOH
 4.285
6.229
3.590
 CG2
CG2
CG1
 C14
O3S
O
4xud 1 P21964 99.54 1e-161 X-RAY
 2015-04-15 VAL A:206 A:253 71.0 0.458 S -65.2 135.0 71.0 0.458 0.0 43H
MES
HOH
 4.385
5.763
3.739
 CG2
CG2
CG1
 C18
O1S
O
4xue 1 P21964 100.0 1e-159 X-RAY
 2015-04-15 VAL A:203 B:253 75.0 0.484 S -66.1 131.7 75.0 0.484 0.0 43J
HOH
 9.986
3.785
 CG1
CA
 C
O
VAL B:203 A:253 77.0 0.497 S -74.4 137.5 NA NA NA
3a7e 1 P21964 100.0 1e-159 X-RAY
 2010-09-15 VAL A:205 A:203 50.0 0.323 -104.3 143.8 50.0 0.323 0.0 DNC
HOH
 8.277
5.886
 CG1
CG1
 O6
O
3bwm 1 P21964 100.0 2e-159 X-RAY
 2008-06-03 VAL A:202 A:203 76.0 0.49 S -55.7 132.2 76.0 0.49 0.0 DNC
HOH
 7.459
5.796
 CG1
O
 O6
O
3bwy 1 Q6ICE6 99.53 5e-159 X-RAY
 2008-06-03 VAL A:202 A:203 69.0 0.445 S -63.0 131.9 69.0 0.445 0.0 DNC
HOH
 7.256
4.181
 CG1
N
 O6
O
3nwe 1 P22734 82.03 6e-135 X-RAY
 2011-08-03 VAL A:203 A:203 51.0 0.329 S -133.4 129.0 51.0 0.329 0.0 CL
662
HOH
 8.350
4.993
2.873
 H
HG11
HA
 CL
H36
O
3oe4 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 VAL A:203 A:203 110.0 0.71 -92.5 119.4 110.0 0.71 0.0 HOH
 3.635
 CA
 O
3oe5 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 VAL A:203 A:203 109.0 0.703 -91.2 118.0 109.0 0.703 0.0 611
HOH
 9.966
3.661
 CG2
CA
 O25
O
3ozr 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 VAL A:203 A:203 60.0 0.387 S -72.6 134.4 60.0 0.387 0.0 OZR
HOH
 7.901
3.977
 CG1
N
 O23
O
3ozs 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 VAL A:203 A:203 110.0 0.71 -92.7 119.7 110.0 0.71 0.0 OZS
HOH
 9.966
3.632
 CG2
CA
 O32
O
3ozt 1 P22734 82.03 6e-135 X-RAY
 2011-03-16 VAL A:203 A:203 110.0 0.71 -92.4 119.6 110.0 0.71 0.0 HOH
 3.684
 CA
 O
3r6t 1 P22734 82.03 6e-135 X-RAY
 2012-02-01 VAL A:203 A:246 57.0 0.368 S -128.9 129.6 57.0 0.368 0.0 CL
LU1
NHE
HOH
 8.790
6.839
6.276
3.774
 O
CG1
CG2
CG1
 CL
C24
C4'
O
3u81 1 P22734 82.03 6e-135 X-RAY
 2012-02-01 VAL A:203 A:203 50.0 0.323 E -129.6 150.3 50.0 0.323 0.0 HOH
 6.243
 N
 O
4pym 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 VAL A:203 A:246 50.0 0.323 E -133.5 150.5 50.0 0.323 0.0 HOH
 2.758
 HG23
 O
4pyn 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 VAL A:203 A:246 50.0 0.323 E -126.8 150.3 50.0 0.323 0.0 HOH
 6.291
 N
 O
4pyo 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 VAL A:203 A:246 49.0 0.316 E -131.8 147.5 49.0 0.316 0.0 HOH
 3.921
 CA
 O
VAL B:203 B:246 56.0 0.361 E -138.5 153.2 NA NA NA
4pyq 1 P22734 82.03 6e-135 X-RAY
 2014-06-11 VAL A:203 A:246 44.0 0.284 -60.2 129.3 44.0 0.284 0.0 NA
HOH
 9.619
2.510
 HA
H
 NA
O
VAL B:203 B:246 47.0 0.303 -54.5 123.8 47.0 0.303 0.0 HOH
 2.355
 H
 O
5lqj 1 P22734 82.03 6e-135 X-RAY
 2016-09-28 VAL A:203 A:203 51.0 0.329 E -137.8 140.9 51.0 0.329 0.0 HOH
 6.287
 CG1
 O
VAL B:203 B:203 145.0 0.935 -71.3 129.5 NA NA NA
VAL C:203 C:203 52.0 0.335 E -131.5 145.6 NA NA NA
VAL D:203 D:203 148.0 0.955 -76.7 131.8 NA NA NA
5lqk 1 P22734 82.03 6e-135 X-RAY
 2016-08-31 VAL A:203 A:203 63.0 0.406 S -108.6 128.2 63.0 0.406 0.0 CL
72M
HOH
 9.148
6.357
3.703
 O
CG1
CG1
 CL
C37
O
5lqn 1 P22734 82.03 6e-135 X-RAY
 2016-10-05 VAL A:203 A:203 53.0 0.342 E -137.4 146.6 53.0 0.342 0.0 HOH
 3.415
 CA
 O
5lr6 1 P22734 82.03 6e-135 X-RAY
 2016-08-31 VAL A:203 A:203 56.0 0.361 -134.3 149.8 56.0 0.361 0.0 HOH
 7.364
 O
 O
VAL B:203 B:203 53.0 0.342 E -148.4 164.6 NA NA NA
VAL C:203 C:203 53.0 0.342 E -140.4 172.7 NA NA NA
VAL D:203 D:203 49.0 0.316 E -137.8 139.3 NA NA NA
5p8w 1 P22734 82.03 6e-135 X-RAY
 2016-09-07 VAL A:203 A:203 89.0 0.574 -126.9 151.5 20.0 0.129 0.445 B:P22734:0.335
C:P22734:0.11
 O01
HOH
 5.505
3.871
 C
CG1
 C13
O
VAL B:203 B:203 85.0 0.548 -126.9 165.4 19.0 0.123 0.425 A:P22734:0.426
 HOH
 3.622
 CA
 O
VAL C:203 C:203 43.0 0.277 -71.8 124.3 27.0 0.174 0.103 B:P22734:0.103
 FMT
HOH
 8.715
3.236
 CG1
O
 O1
O
5p8x 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 VAL A:203 A:203 53.0 0.342 S -133.6 127.8 53.0 0.342 0.0 CL
75Z
NHE
D1D
HOH
 8.785
6.994
6.951
5.627
3.796
 O
CG1
CG2
CG2
CG1
 CL
C13
C4'
S1
O
5p8y 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 VAL A:203 A:203 56.0 0.361 S -134.6 128.4 56.0 0.361 0.0 CL
NHE
D1D
763
HOH
 8.713
6.781
5.562
6.947
3.798
 O
CG2
CG2
CG1
CG1
 CL
C4'
S4
C9
O
5p8z 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 VAL A:203 A:203 53.0 0.342 S -138.0 127.6 53.0 0.342 0.0 CL
766
NHE
D1D
HOH
 8.713
6.982
6.925
5.584
3.867
 O
CG1
CG2
CG2
CG1
 CL
C28
C4'
S1
O
5p90 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 VAL A:203 A:203 58.0 0.374 S -133.5 129.7 58.0 0.374 0.0 CL
769
D1D
NHE
HOH
 8.757
6.987
5.519
6.994
3.751
 O
CG1
CG2
CG2
CG1
 CL
C3
S1
C4'
O
5p91 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 VAL A:203 A:203 54.0 0.348 S -135.8 129.9 54.0 0.348 0.0 CL
76B
HOH
 8.754
7.132
3.811
 O
CG1
CG1
 CL
C29
O
5p92 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 VAL A:203 A:203 53.0 0.342 S -133.3 130.2 53.0 0.342 0.0 CL
76G
D1D
NHE
HOH
 8.663
7.048
5.754
7.140
3.784
 O
CG1
CG2
CG2
CG1
 CL
C26
S1
C3'
O
5p93 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 VAL A:203 A:203 53.0 0.342 S -132.5 131.8 53.0 0.342 0.0 CL
76S
HOH
 8.824
7.318
3.833
 O
CG1
CG1
 CL
C9
O
5p94 1 P22734 82.03 6e-135 X-RAY
 2017-08-30 VAL A:203 A:203 50.0 0.323 S -137.1 130.8 50.0 0.323 0.0 CL
76T
HOH
 8.696
6.875
3.731
 O
CG1
CG1
 CL
C32
O
5p9n 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 51.0 0.329 S -136.3 130.3 51.0 0.329 0.0 CL
NHE
D1D
7JE
8JE
HOH
 8.721
6.629
5.620
6.881
6.883
3.860
 O
CG2
CG2
CG1
CG1
CG1
 CL
C4'
S4
C32
C32
O
5p9o 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 57.0 0.368 S -129.2 130.8 57.0 0.368 0.0 7JF
CL
DTD
NHE
NHE
HOH
 7.125
8.834
5.743
7.015
7.051
3.574
 CG1
O
CG2
CG2
CG2
CA
 C25
CL
S4
C4'
C5'
O
5p9p 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 55.0 0.355 S -133.5 130.3 55.0 0.355 0.0 CL
7JG
HOH
 8.831
6.959
3.840
 O
CG1
CG1
 CL
C10
O
5p9q 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 58.0 0.374 S -134.2 128.0 58.0 0.374 0.0 CL
7JH
D1D
HOH
 8.882
6.506
5.568
3.470
 O
CG1
CG2
CA
 CL
C18
S1
O
5p9r 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 72.0 0.465 S -75.0 135.2 72.0 0.465 0.0 7JJ
HOH
 6.921
3.607
 CG1
CA
 C15
O
VAL B:203 B:203 70.0 0.452 S -66.7 136.3 NA NA NA
5p9s 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 68.0 0.439 S -58.6 141.8 68.0 0.439 0.0 7JK
HOH
 5.506
3.844
 CG2
C
 C26
O
5p9t 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 52.0 0.335 S -136.0 129.3 52.0 0.335 0.0 CL
7JD
D1D
NHE
HOH
 8.857
6.937
5.573
6.821
3.827
 O
CG1
CG2
CG2
CG1
 CL
C7
S1
C4'
O
5p9u 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 110.0 0.71 -90.1 118.8 110.0 0.71 0.0 HOH
 3.716
 CA
 O
5p9v 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 58.0 0.374 S -133.6 128.0 58.0 0.374 0.0 CL
D1D
7JM
HOH
 8.876
5.650
6.897
3.879
 O
CG2
CG1
CG1
 CL
S1
C15
O
5p9x 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 53.0 0.342 S -139.3 131.4 53.0 0.342 0.0 CL
NHE
7JO
HOH
 8.743
6.774
6.940
3.759
 O
CG2
CG1
CG1
 CL
C4'
C3
O
5p9y 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 56.0 0.361 S -134.2 129.3 56.0 0.361 0.0 7JP
CL
D1D
NHE
HOH
 6.750
8.707
5.567
6.933
3.838
 CG1
O
CG2
CG2
CG1
 C29
CL
S4
C4'
O
5p9z 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 53.0 0.342 S -137.8 127.0 53.0 0.342 0.0 CL
7JQ
D1D
HOH
 8.726
6.729
5.803
3.896
 O
CG1
CG2
CG1
 CL
C14
S1
O
5pa0 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 52.0 0.335 S -136.4 130.1 52.0 0.335 0.0 7JR
CL
CXS
SO4
HOH
 5.490
8.517
5.785
9.914
2.861
 HG11
H
HG21
HG23
HA
 H121
CL
H71
O3
O
5pa2 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 53.0 0.342 S -134.8 129.8 53.0 0.342 0.0 CL
7JU
D1D
HOH
 8.826
7.002
5.606
3.753
 O
CG1
CG2
CG1
 CL
C15
S1
O
5pa3 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 59.0 0.381 -137.5 122.2 59.0 0.381 0.0 7JV
CL
D1D
HOH
 6.746
8.799
5.508
3.497
 CG1
O
CG2
CA
 C17
CL
S1
O
5pa4 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 57.0 0.368 S -139.1 126.5 57.0 0.368 0.0 7JD
HOH
 6.814
3.760
 CG1
CG1
 C9
O
5pa5 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 58.0 0.374 S -134.2 128.0 58.0 0.374 0.0 CL
7JH
D1D
HOH
 8.882
6.506
5.568
3.470
 O
CG1
CG2
CA
 CL
C18
S1
O
5pa6 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 53.0 0.342 S -136.6 130.8 53.0 0.342 0.0 7JW
CL
NHE
HOH
 6.979
8.594
7.010
3.847
 CG1
O
CG2
CG1
 C14
CL
C3'
O
5pa7 1 P22734 82.03 6e-135 X-RAY
 2017-11-22 VAL A:203 A:203 53.0 0.342 E -147.4 146.6 53.0 0.342 0.0 7JX
HOH
 7.009
8.001
 CG1
O
 BR1
O
VAL B:203 B:203 51.0 0.329 E -138.8 149.5 NA NA NA
5k09 1 P22734 82.03 7e-135 X-RAY
 2016-09-07 VAL A:202 A:203 46.0 0.297 E -119.0 93.5 46.0 0.297 0.0 HOH
 4.044
 N
 O
VAL B:202 B:203 45.0 0.29 E -118.4 81.9 NA NA NA
VAL C:202 C:203 45.0 0.29 E -129.3 80.0 NA NA NA
VAL D:202 D:203 44.0 0.284 E -119.5 85.9 NA NA NA
VAL E:202 E:203 42.0 0.271 E -132.5 84.1 NA NA NA
VAL F:202 F:203 50.0 0.323 E -103.6 84.6 NA NA NA
VAL G:202 G:203 44.0 0.284 E -126.0 83.9 NA NA NA
VAL H:202 H:203 43.0 0.277 E -130.5 91.7 NA NA NA
VAL I:202 I:203 48.0 0.31 E -122.6 88.7 NA NA NA
VAL J:202 J:203 43.0 0.277 E -121.4 79.0 NA NA NA
VAL K:202 K:203 44.0 0.284 E -127.8 90.5 NA NA NA
VAL L:202 L:203 44.0 0.284 E -119.3 86.2 NA NA NA
VAL M:202 M:203 43.0 0.277 E -132.9 88.8 NA NA NA
VAL N:202 N:203 42.0 0.271 E -129.0 87.1 NA NA NA
VAL O:202 O:203 47.0 0.303 E -130.2 85.3 NA NA NA
VAL P:202 P:203 46.0 0.297 E -126.3 87.6 NA NA NA
VAL Q:202 Q:203 41.0 0.265 E -129.9 86.5 NA NA NA
VAL R:202 R:203 41.0 0.265 E -121.7 98.6 NA NA NA
VAL S:202 S:203 44.0 0.284 E -131.0 89.1 NA NA NA
VAL T:202 T:203 45.0 0.29 E -123.8 83.2 NA NA NA
VAL U:202 U:203 46.0 0.297 E -131.8 86.0 NA NA NA
VAL V:202 V:203 41.0 0.265 E -127.4 82.4 NA NA NA
VAL W:202 W:203 46.0 0.297 E -126.6 91.7 NA NA NA
VAL X:202 X:203 48.0 0.31 E -129.7 81.3 NA NA NA
5k0b 1 P22734 81.65 8e-135 X-RAY
 2016-09-07 VAL A:202 A:203 69.0 0.445 -116.8 158.4 69.0 0.445 0.0 HOH
 3.357
 CA
 O
VAL B:202 B:203 70.0 0.452 -124.1 160.3 NA NA NA
VAL C:202 C:203 84.0 0.542 -114.1 156.7 NA NA NA
VAL D:202 D:203 81.0 0.523 -114.1 157.2 NA NA NA
VAL E:202 E:203 86.0 0.555 -117.9 166.2 NA NA NA
VAL F:202 F:203 69.0 0.445 -123.4 151.4 NA NA NA
VAL G:202 G:203 67.0 0.432 -122.4 161.4 NA NA NA
VAL H:202 H:203 81.0 0.523 -115.1 156.5 NA NA NA
4p7f 1 O88587 81.19 1e-134 X-RAY
 2014-06-11 VAL A:203 A:246 35.0 0.226 -63.0 126.2 35.0 0.226 0.0 PI
HOH
 4.057
2.209
 HG21
H
 O3
O
5k0f 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 VAL A:202 A:203 51.0 0.329 E -137.8 148.5 51.0 0.329 0.0 HOH
 3.338
 CG2
 O
VAL B:202 B:203 66.0 0.426 S -124.4 160.1 NA NA NA
5k0g 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 VAL A:202 A:203 54.0 0.348 E -139.2 148.4 54.0 0.348 0.0 HOH
 3.381
 CG2
 O
VAL B:202 B:203 57.0 0.368 -123.8 158.2 NA NA NA
5k0j 1 P22734 82.41 1e-134 X-RAY
 2016-09-07 VAL A:202 A:203 50.0 0.323 -133.2 145.8 50.0 0.323 0.0 HOH
 3.136
 CG2
 O
VAL B:202 B:203 70.0 0.452 S -116.7 156.8 NA NA NA
5k0n 1 P22734 81.94 4e-134 X-RAY
 2016-09-07 VAL A:202 A:203 55.0 0.355 E -139.3 148.3 55.0 0.355 0.0 HOH
 7.839
 C
 O
VAL B:202 B:203 48.0 0.31 E -135.6 150.6 NA NA NA
VAL C:202 C:203 48.0 0.31 -131.8 146.1 NA NA NA
VAL D:202 D:203 52.0 0.335 -132.5 132.8 NA NA NA
5k0l 1 P22734 81.94 4e-134 X-RAY
 2016-09-07 VAL A:202 A:203 56.0 0.361 E -141.4 146.0 56.0 0.361 0.0 HOH
 7.607
 C
 O
VAL B:202 B:203 46.0 0.297 E -135.0 149.7 NA NA NA
VAL C:202 C:203 58.0 0.374 S -119.8 160.9 NA NA NA
VAL D:202 D:203 46.0 0.297 -137.0 144.1 NA NA NA
5k0c 1 P22734 82.33 5e-134 X-RAY
 2016-09-07 VAL A:202 A:203 56.0 0.361 E -146.2 151.6 56.0 0.361 0.0 HOH
 3.336
 CG2
 O
VAL B:202 B:203 68.0 0.439 -104.8 161.5 NA NA NA
5k0e 1 P22734 82.33 5e-134 X-RAY
 2016-09-07 VAL A:202 A:203 58.0 0.374 E -152.9 150.5 58.0 0.374 0.0
6aw5 1 ? 81.0 5e-134 X-RAY
 2018-09-12 VAL A:202 A:202 45.0 0.29 -63.5 129.4 45.0 0.29 0.0 HOH
 2.827
 N
 O
6aw6 1 ? 81.0 5e-134 X-RAY
 2018-09-12 VAL A:202 A:202 38.0 0.245 -56.8 130.1 38.0 0.245 0.0 SO4
HOH
 4.721
2.677
 CG2
O
 O1
O
6aw9 1 ? 81.0 5e-134 X-RAY
 2018-09-12 VAL A:202 A:202 80.0 0.516 -132.1 147.5 80.0 0.516 0.0 CA
SAH
HOH
 8.164
9.154
7.916
 CG1
CG1
CG1
 CA
SD
O
VAL B:202 B:202 68.0 0.439 -99.7 166.2 NA NA NA
VAL C:202 C:202 64.0 0.413 -77.1 131.8 NA NA NA
6aw4 1 ? 80.54 2e-133 X-RAY
 2018-09-12 VAL A:202 A:202 40.0 0.258 -62.8 129.2 40.0 0.258 0.0 PO4
HOH
 4.600
2.733
 CG2
O
 O2
O
6aw7 1 ? 80.54 2e-133 X-RAY
 2018-09-12 VAL A:202 A:202 86.0 0.555 -130.4 153.9 86.0 0.555 0.0 CA
SAH
HOH
 8.372
9.296
3.541
 CG1
CG1
CA
 CA
SD
O
VAL B:202 B:202 73.0 0.471 -116.4 162.4 NA NA NA
6aw8 1 ? 80.54 2e-133 X-RAY
 2018-09-12 VAL A:202 A:202 86.0 0.555 -122.5 145.2 86.0 0.555 0.0 CA
SAH
HOH
 8.164
9.222
3.563
 CG1
CG1
CA
 CA
SD
O
VAL B:202 B:202 73.0 0.471 -117.1 162.4 NA NA NA
VAL C:202 C:202 69.0 0.445 S -79.0 137.4 NA NA NA
5k05 1 P22734 82.24 2e-133 X-RAY
 2016-09-07 VAL A:201 A:203 54.0 0.348 E -141.3 153.5 54.0 0.348 0.0 HOH
 3.145
 CG2
 O
VAL B:201 B:203 52.0 0.335 E -141.8 151.2 NA NA NA
1h1d 1 P22734 81.11 2e-133 X-RAY
 2003-07-17 VAL A:203 A:203 57.0 0.368 S -74.1 137.2 57.0 0.368 0.0 BIA
HOH
 7.633
3.520
 CG2
CG1
 N2
O
1jr4 1 P22734 81.11 2e-133 X-RAY
 2002-08-10 VAL A:203 A:203 59.0 0.381 -130.8 131.5 59.0 0.381 0.0 CL4
 7.666
 CG1
 O33
1vid 1 P22734 81.11 2e-133 X-RAY
 1996-07-11 VAL A:203 A:203 61.0 0.394 -80.1 132.3 61.0 0.394 0.0 DNC
HOH
 7.539
3.509
 CG1
CA
 O6
O
2cl5 1 P22734 81.11 2e-133 X-RAY
 2006-06-28 VAL A:203 A:203 73.0 0.471 S -65.2 131.2 73.0 0.471 0.0 BIE
HOH
 9.658
3.754
 CG1
CA
 C6
O
VAL B:203 B:203 63.0 0.406 S -63.0 131.1 NA NA NA
3hvh 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 VAL A:203 A:246 54.0 0.348 S -132.7 128.8 54.0 0.348 0.0 542
CXS
CL
SO4
HOH
 6.816
6.004
8.736
8.733
3.786
 CG1
CG2
O
CG2
CG1
 C28
C7
CL
O1
O
3hvi 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 VAL A:203 A:246 54.0 0.348 S -136.8 128.1 54.0 0.348 0.0 CL
619
HOH
 8.762
6.724
3.822
 O
CG1
CG1
 CL
C28
O
3hvj 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 VAL A:203 A:246 65.0 0.419 -78.7 138.4 65.0 0.419 0.0 705
CL
BTB
HOH
 6.587
8.947
9.566
3.726
 CG1
O
CG2
C
 C28
CL
C3
O
VAL B:203 B:246 68.0 0.439 S -60.7 132.4 NA NA NA
3hvk 1 P22734 81.11 2e-133 X-RAY
 2009-10-13 VAL A:203 A:246 56.0 0.361 S -136.6 126.2 56.0 0.361 0.0 CL
NHE
719
HOH
 8.754
6.667
6.849
3.844
 O
CG2
CG1
CG1
 CL
C4'
C34
O
3nw9 1 P22734 81.11 2e-133 X-RAY
 2011-03-16 VAL A:203 A:203 54.0 0.348 S -137.8 129.2 54.0 0.348 0.0 CL
NHE
637
HOH
 8.707
6.863
6.834
3.922
 O
CG2
CG1
CG1
 CL
C4'
C28
O
3nwb 1 P22734 81.11 2e-133 X-RAY
 2011-08-03 VAL A:203 A:203 53.0 0.342 S -134.4 128.9 53.0 0.342 0.0 CL
659
NHE
HOH
 8.319
5.080
5.197
2.777
 H
HG11
HG21
HA
 CL
H19
H4'1
O
3s68 1 P22734 81.11 2e-133 X-RAY
 2012-02-01 VAL A:203 A:203 63.0 0.406 S -63.3 134.0 63.0 0.406 0.0 CL
CL
TCW
HOH
 8.934
3.273
7.011
2.914
 O
HG23
HG11
HG22
 CL
CL
O13
O
4p7g 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 VAL A:203 A:246 35.0 0.226 -53.9 111.4 35.0 0.226 0.0 HOH
 6.918
 CG2
 O
VAL B:203 B:246 35.0 0.226 -53.7 113.8 NA NA NA
VAL C:203 C:246 35.0 0.226 -53.5 112.5 NA NA NA
VAL D:203 D:246 36.0 0.232 -55.6 114.2 NA NA NA
4p7j 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 VAL A:203 A:246 33.0 0.213 -59.1 129.5 33.0 0.213 0.0 HOH
 2.675
 O
 O
4p7k 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 VAL A:203 A:246 46.0 0.297 E -128.9 148.0 46.0 0.297 0.0 HOH
 2.553
 HG22
 O
4pyl 1 P22734 81.11 2e-133 X-RAY
 2014-06-18 VAL A:203 A:246 61.0 0.394 -63.0 123.7 61.0 0.394 0.0 TCW
HOH
 7.522
4.934
 CG1
N
 O13
O
5lqc 1 P22734 81.11 2e-133 X-RAY
 2016-08-31 VAL A:203 A:203 114.0 0.735 -75.3 122.3 31.0 0.2 0.535 A:P22734:0.535
 542
542
HOH
 8.268
6.832
3.296
 CG2
CG1
CA
 F30
C28
O
5lqr 1 P22734 81.11 2e-133 X-RAY
 2016-10-05 VAL A:203 A:203 57.0 0.368 S -132.1 126.5 57.0 0.368 0.0 CL
NHE
72W
HOH
 8.660
6.419
6.839
3.721
 O
CG2
CG1
CG1
 CL
C4'
C34
O
5lqu 1 P22734 81.11 2e-133 X-RAY
 2016-10-05 VAL A:203 A:203 64.0 0.413 -71.8 133.2 64.0 0.413 0.0 619
CL
BTB
HOH
 6.724
8.965
9.352
3.616
 CG1
O
CG2
CA
 C28
CL
C3
O
VAL B:203 B:203 67.0 0.432 S -58.5 130.5 NA NA NA
5p95 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 VAL A:203 A:203 53.0 0.342 S -138.4 131.8 53.0 0.342 0.0 CL
77G
D1D
NHE
HOH
 8.743
6.934
5.499
6.099
3.693
 O
CG1
CG2
CG2
CG1
 CL
C27
S4
C5'
O
5p96 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 VAL A:203 A:203 52.0 0.335 S -137.9 130.7 52.0 0.335 0.0 77H
D1D
NHE
CL
HOH
 6.850
5.559
6.167
8.695
3.760
 CG1
CG2
CG2
O
CG1
 C26
S4
C5'
CL
O
5p97 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 VAL A:203 A:203 53.0 0.342 S -139.2 131.5 53.0 0.342 0.0 CL
NHE
77K
HOH
 8.723
6.635
6.945
3.771
 O
CG2
CG1
CG1
 CL
C4'
C9
O
5p98 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 VAL A:203 A:203 54.0 0.348 S -141.5 132.9 54.0 0.348 0.0 CL
D1D
NHE
77L
HOH
 8.811
5.530
6.669
7.073
3.623
 O
CG2
CG2
CG1
CG1
 CL
S1
C4'
C9
O
5p99 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 VAL A:203 A:203 54.0 0.348 S -138.4 132.1 54.0 0.348 0.0 77M
CL
HOH
 6.987
8.726
3.712
 CG1
O
CG1
 C9
CL
O
5p9a 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 VAL A:203 A:203 52.0 0.335 S -133.8 127.1 52.0 0.335 0.0 77N
D1D
HOH
 6.823
6.424
3.559
 CG1
CG2
CA
 C27
S1
O
5p9b 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 VAL A:203 A:203 52.0 0.335 S -142.0 131.9 52.0 0.335 0.0 CL
77P
NHE
HOH
 8.711
7.036
6.645
3.527
 O
CG1
CG2
CA
 CL
C3
C4'
O
5p9c 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 VAL A:203 A:203 55.0 0.355 S -132.5 129.5 55.0 0.355 0.0 77Q
D1D
HOH
 6.794
5.528
3.478
 CG1
CG2
CA
 C24
S4
O
5p9d 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 VAL A:203 A:203 53.0 0.342 S -135.9 132.6 53.0 0.342 0.0 77R
D1D
HOH
 6.912
5.547
3.754
 CG1
CG2
CG1
 C22
S1
O
5p9e 1 P22734 81.11 2e-133 X-RAY
 2017-08-30 VAL A:203 A:203 56.0 0.361 S -139.5 132.4 56.0 0.361 0.0 CL
77S
D1D
HOH
 8.709
6.947
5.606
3.532
 O
CG1
CG2
CA
 CL
C9
S4
O
5p9w 1 P22734 81.11 2e-133 X-RAY
 2017-11-22 VAL A:203 A:203 52.0 0.335 S -137.4 133.2 52.0 0.335 0.0 CL
7JN
D1D
NHE
HOH
 8.745
6.771
5.688
6.514
3.743
 O
CG1
CG2
CG2
CG1
 CL
C36
S1
C4'
O
5pa1 1 P22734 81.11 2e-133 X-RAY
 2017-11-22 VAL A:203 A:203 53.0 0.342 S -137.3 130.8 53.0 0.342 0.0 CL
D1D
NHE
7JS
HOH
 8.737
5.734
7.019
6.796
3.773
 O
CG2
CG2
CG1
CG1
 CL
S1
C4'
C14
O
2zlb 1 P22734 81.11 3e-133 X-RAY
 2008-10-07 VAL A:205 A:203 34.0 0.219 -58.2 128.4 34.0 0.219 0.0 HOH
 2.847
 O
 O
2zth 1 P22734 81.11 3e-133 X-RAY
 2009-01-13 VAL A:205 A:203 55.0 0.355 E -112.5 142.6 55.0 0.355 0.0 HOH
 4.060
 CA
 O
2zvj 1 P22734 81.11 3e-133 X-RAY
 2009-01-06 VAL A:205 A:203 71.0 0.458 -104.9 141.0 71.0 0.458 0.0 KOM
HOH
 9.862
3.236
 O
CA
 C1
O
3a7d 1 P22734 81.11 3e-133 X-RAY
 2010-09-15 VAL A:205 A:203 70.0 0.452 S -71.7 133.2 70.0 0.452 0.0 SO4
FBN
HOH
 8.503
8.320
3.541
 O
CB
CG1
 O1
O56
O
6gy1 1 P22734 81.11 3e-133 X-RAY
 2018-10-10 VAL A:205 A:203 56.0 0.361 S -64.4 133.6 56.0 0.361 0.0 FGQ
HOH
 8.368
3.516
 CG1
CG1
 F21
O
6lfe 1 P22734 81.11 3e-133 X-RAY
 2020-03-04 VAL A:205 A:203 51.0 0.329 -135.7 128.7 51.0 0.329 0.0 EAO
HOH
 7.274
3.798
 CG1
CG1
 C14
O
5k01 1 P22734 81.78 1e-132 X-RAY
 2016-09-07 VAL A:201 A:203 49.0 0.316 E -144.6 144.4 49.0 0.316 0.0 HOH
 2.806
 HA
 O
5k03 1 P22734 81.78 1e-132 X-RAY
 2016-09-07 VAL A:201 A:203 46.0 0.297 E -138.0 140.9 46.0 0.297 0.0 HOH
 3.562
 CG2
 O
4p58 1 O88587 81.6 2e-131 X-RAY
 2014-06-25 VAL A:200 A:246 44.0 0.284 -66.5 130.5 44.0 0.284 0.0 HOH
 3.065
 N
 O
5fhq 1 P22734 81.22 9e-131 X-RAY
 2016-02-03 VAL A:201 A:203 115.0 0.742 -87.4 114.8 115.0 0.742 0.0 DNC
HOH
 9.460
2.847
 HG21
HA
 O5
O
5lqa 1 P22734 81.22 9e-131 X-RAY
 2016-10-05 VAL A:201 A:203 53.0 0.342 S -132.9 128.2 53.0 0.342 0.0 NHE
619
CL
HOH
 6.464
6.908
8.764
3.859
 CG2
CG1
O
CG1
 C4'
C28
CL
O
5fhr 1 P22734 80.75 2e-129 X-RAY
 2016-02-03 VAL A:201 A:246 140.0 0.903 -110.5 123.5 57.0 0.368 0.535 B:P22734:0.535
 DNC
HOH
 7.233
2.962
 CG1
N
 O5
O
VAL B:201 B:246 139.0 0.897 -113.4 120.3 55.0 0.355 0.542 A:P22734:0.542
 DNC
HOH
 7.083
2.905
 CG1
N
 O5
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21964-f1 1 P21964 100.0 0.0 VAL A:253 A:253 23.0 0.148 S -115.0 127.1