Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 30032743 . A C CCDS13861.1:NM_000268.3:c.118Aag>Cag_NP_000259.1:p.40K>Q Homo sapiens neurofibromin 2 (NF2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6cds 1 P35240 99.71 0.0 X-RAY
 2018-07-18 LYS A:40 A:40 141.0 0.705 T -76.0 -20.0 141.0 0.705 0.0 HOH
 3.888
 CB
 O
LYS B:40 B:40 141.0 0.705 T -75.4 -20.5 NA NA NA
7lwh 1 P35240 99.41 0.0 X-RAY
 2021-08-11 LYS A:40 A:40 147.0 0.735 T -95.6 33.3 147.0 0.735 0.0
1isn 1 P46662 99.38 0.0 X-RAY
 2002-04-03 LYS A:23 A:40 68.0 NA T -80.9 14.6 68.0 NA NA
4zrj 1 P35240 100.0 0.0 X-RAY
 2015-06-17 LYS A:40 A:40 129.0 0.645 T -83.9 -6.9 129.0 0.645 0.0 GOL
HOH
 7.366
3.413
 NZ
NZ
 O1
O
4zri 1 P35240 100.0 0.0 X-RAY
 2015-06-17 LYS A:44 A:40 134.0 0.67 T -104.1 0.3 134.0 0.67 0.0
LYS B:44 B:40 83.0 NA S -114.1 13.6 NA NA NA
4zrk 1 P46662 99.38 0.0 X-RAY
 2015-06-17 LYS A:44 A:40 61.0 NA T -95.9 5.1 61.0 NA NA
LYS B:44 B:40 66.0 NA T -98.4 1.7 NA NA NA
LYS C:44 C:40 57.0 NA T -99.2 2.9 NA NA NA
LYS D:44 D:40 51.0 NA T -98.8 0.6 NA NA NA
1h4r 1 P35240 100.0 0.0 X-RAY
 2002-01-16 LYS A:41 A:40 150.0 0.75 T -110.8 14.0 150.0 0.75 0.0 SO4
HOH
 2.616
2.675
 NZ
O
 O2
O
LYS B:41 B:40 155.0 0.775 T -105.6 4.7 155.0 0.775 0.0 SO4
HOH
 2.297
3.860
 NZ
N
 O3
O
4p7i 1 P46662 99.36 0.0 X-RAY
 2014-04-09 LYS A:44 A:40 150.0 0.75 T -111.0 21.0 150.0 0.75 0.0
LYS B:44 B:40 166.0 0.83 T -108.3 16.3 NA NA NA
3u8z 1 P35240 100.0 0.0 X-RAY
 2011-11-02 LYS A:28 A:40 168.0 0.84 T -99.7 8.9 164.0 0.82 0.02 C:P35240:0.02
 HOH
 3.909
 C
 O
LYS B:28 B:40 167.0 0.835 T -99.1 8.7 NA NA NA
LYS C:28 C:40 167.0 0.835 T -98.5 8.2 167.0 0.835 0.0 HOH
 9.894
 CB
 O
LYS D:28 D:40 166.0 0.83 T -99.5 9.0 NA NA NA
3wa0 1 P46662 99.32 0.0 X-RAY
 2014-05-28 LYS A:27 A:40 161.0 0.805 T -95.5 5.3 161.0 0.805 0.0
LYS B:27 B:40 163.0 0.815 T -96.7 4.9 NA NA NA
LYS C:27 C:40 191.0 0.955 T -96.2 5.6 NA NA NA
LYS D:27 D:40 137.0 0.685 T -81.9 -7.2 NA NA NA
LYS E:27 E:40 174.0 0.87 T -91.7 -4.9 NA NA NA
LYS F:27 F:40 141.0 0.705 S -94.1 -0.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p35240-f1 1 P35240 100.0 0.0 LYS A:40 A:40 140.0 0.7 T -91.8 -7.4