Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 30032794 . C A CCDS13861.1:NM_000268.3:c.169Cga>Aga_NP_000259.1:p.57R>R Homo sapiens neurofibromin 2 (NF2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6cds 1 P35240 99.71 0.0 X-RAY
 2018-07-18 ARG A:57 A:57 205.0 0.911 -105.7 -26.1 205.0 0.911 0.0 PIO
HOH
 4.297
2.761
 O
NH2
 O1B
O
ARG B:57 B:57 205.0 0.911 -106.5 -26.3 NA NA NA
7lwh 1 P35240 99.41 0.0 X-RAY
 2021-08-11 ARG A:57 A:57 88.0 0.391 -96.4 -21.0 88.0 0.391 0.0 HOH
 2.580
 O
 O
1isn 1 P46662 99.38 0.0 X-RAY
 2002-04-03 ARG A:40 A:57 97.0 0.431 -120.9 -7.8 97.0 0.431 0.0
4zrj 1 P35240 100.0 0.0 X-RAY
 2015-06-17 ARG A:57 A:57 183.0 0.813 -106.2 -31.1 183.0 0.813 0.0 GOL
HOH
 9.663
2.861
 O
NH1
 O3
O
4zri 1 P35240 100.0 0.0 X-RAY
 2015-06-17 ARG A:61 A:57 187.0 0.831 -98.4 -21.1 187.0 0.831 0.0
ARG B:61 B:57 213.0 0.947 S -93.4 -21.5 NA NA NA
4zrk 1 P46662 99.38 0.0 X-RAY
 2015-06-17 ARG A:61 A:57 173.0 0.769 -101.8 -28.1 173.0 0.769 0.0 HOH
 8.383
 O
 O
ARG B:61 B:57 164.0 0.729 -102.6 -31.7 NA NA NA
ARG C:61 C:57 181.0 0.804 -101.4 -28.2 NA NA NA
ARG D:61 D:57 168.0 0.747 -102.2 -29.4 NA NA NA
1h4r 1 P35240 100.0 0.0 X-RAY
 2002-01-16 ARG A:58 A:57 179.0 0.796 -108.0 -18.5 179.0 0.796 0.0 HOH
 2.668
 O
 O
ARG B:58 B:57 175.0 0.778 -110.2 -12.7 175.0 0.778 0.0 HOH
 2.608
 O
 O
4p7i 1 P46662 99.36 0.0 X-RAY
 2014-04-09 ARG A:61 A:57 185.0 0.822 -98.5 -24.1 185.0 0.822 0.0 HOH
 9.663
 O
 O
ARG B:61 B:57 189.0 0.84 S -96.0 -24.3 NA NA NA
3u8z 1 P35240 100.0 0.0 X-RAY
 2011-11-02 ARG A:45 A:57 179.0 0.796 -105.9 -29.8 68.0 0.302 0.494 C:P35240:0.493
 HOH
 3.549
 NH2
 O
ARG B:45 B:57 180.0 0.8 -104.9 -32.0 NA NA NA
ARG C:45 C:57 182.0 0.809 -106.8 -30.3 65.0 0.289 0.52 A:P35240:0.52
 HOH
 4.221
 CB
 O
ARG D:45 D:57 180.0 0.8 -106.7 -32.0 NA NA NA
3wa0 1 P46662 99.32 0.0 X-RAY
 2014-05-28 ARG A:44 A:57 191.0 0.849 -95.2 -12.4 191.0 0.849 0.0
ARG B:44 B:57 198.0 0.88 -94.4 -11.7 NA NA NA
ARG C:44 C:57 182.0 0.809 -94.3 -13.3 NA NA NA
ARG D:44 D:57 171.0 0.76 -91.7 -17.0 NA NA NA
ARG E:44 E:57 180.0 0.8 -93.6 -15.9 NA NA NA
ARG F:44 F:57 177.0 0.787 -82.0 -34.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p35240-f1 1 P35240 100.0 0.0 ARG A:57 A:57 83.0 0.369 -92.1 -31.7