Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 30051617 . G A CCDS13861.1:NM_000268.3:c.551tGg>tAg_NP_000259.1:p.184W>* Homo sapiens neurofibromin 2 (NF2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6cds 1 P35240 99.71 0.0 X-RAY
 2018-07-18 TRP A:184 A:184 16.0 0.063 H -65.6 -41.5 16.0 0.063 0.0 HOH
 2.753
 NE1
 O
TRP B:184 B:184 40.0 0.157 H -66.1 -41.5 NA NA NA
7lwh 1 P35240 99.41 0.0 X-RAY
 2021-08-11 TRP A:184 A:184 21.0 0.082 H -63.4 -44.7 12.0 0.047 0.035 B:O95835:0.035
 IMD
HOH
 3.826
2.839
 CB
NE1
 C2
O
1isn 1 P46662 99.38 0.0 X-RAY
 2002-04-03 TRP A:167 A:184 20.0 0.078 H -59.9 -36.5 20.0 0.078 0.0
4zrj 1 P35240 100.0 0.0 X-RAY
 2015-06-17 TRP A:184 A:184 27.0 0.106 H -58.7 -44.1 15.0 0.059 0.047 B:P35240:0.047
 HOH
 6.139
 N
 O
4zri 1 P35240 100.0 0.0 X-RAY
 2015-06-17 TRP A:188 A:184 15.0 0.059 H -47.5 -54.8 4.0 0.016 0.043 C:Q9NRM7:0.043
TRP B:188 B:184 20.0 0.078 H -59.5 -45.9 NA NA NA
4zrk 1 P46662 99.38 0.0 X-RAY
 2015-06-17 TRP A:188 A:184 23.0 0.09 H -57.9 -45.4 14.0 0.055 0.035 E:O95835:0.035
TRP B:188 B:184 26.0 0.102 H -51.4 -45.1 NA NA NA
TRP C:188 C:184 24.0 0.094 H -55.8 -42.7 NA NA NA
TRP D:188 D:184 20.0 0.078 H -56.2 -45.3 NA NA NA
1h4r 1 P35240 100.0 0.0 X-RAY
 2002-01-16 TRP A:185 A:184 13.0 0.051 H -65.6 -39.5 13.0 0.051 0.0 SO4
HOH
 9.886
2.900
 CH2
NE1
 O1
O
TRP B:185 B:184 23.0 0.09 H -64.7 -43.8 23.0 0.09 0.0 HOH
 2.887
 NE1
 O
4p7i 1 P46662 99.36 0.0 X-RAY
 2014-04-09 TRP A:188 A:184 13.0 0.051 H -78.9 -34.2 13.0 0.051 0.0
TRP B:188 B:184 19.0 0.075 H -76.0 -26.8 NA NA NA
3u8z 1 P35240 100.0 0.0 X-RAY
 2011-11-02 TRP A:172 A:184 139.0 0.545 H -63.4 -42.7 2.0 0.008 0.537 C:P35240:0.537
 HOH
 6.169
 N
 O
TRP B:172 B:184 140.0 0.549 H -63.1 -42.7 NA NA NA
TRP C:172 C:184 133.0 0.522 H -62.7 -43.2 3.0 0.012 0.51 A:P35240:0.51
 HOH
 3.066
 NE1
 O
TRP D:172 NA:NA DO NA DO DO DO NA NA NA
3wa0 1 P46662 99.32 0.0 X-RAY
 2014-05-28 TRP A:171 A:184 19.0 0.075 H -65.0 -37.4 19.0 0.075 0.0 HOH
 7.052
 CH2
 O
TRP B:171 B:184 17.0 0.067 H -68.9 -40.5 NA NA NA
TRP C:171 C:184 16.0 0.063 H -72.5 -39.1 NA NA NA
TRP D:171 D:184 20.0 0.078 H -71.2 -38.4 NA NA NA
TRP E:171 E:184 19.0 0.075 H -66.2 -42.5 NA NA NA
TRP F:171 F:184 21.0 0.082 H -63.9 -41.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p35240-f1 1 P35240 100.0 0.0 TRP A:184 A:184 7.0 0.027 H -68.3 -42.7