Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 30051619 . G A CCDS13861.1:NM_000268.3:c.553Gag>Aag_NP_000259.1:p.185E>K Homo sapiens neurofibromin 2 (NF2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6cds 1 P35240 99.71 0.0 X-RAY
 2018-07-18 GLU A:185 A:185 12.0 0.063 H -59.7 -39.8 12.0 0.063 0.0 HOH
 7.534
 CB
 O
GLU B:185 B:185 8.0 0.042 H -67.6 -43.1 NA NA NA
7lwh 1 P35240 99.41 0.0 X-RAY
 2021-08-11 GLU A:185 A:185 11.0 0.058 H -59.6 -40.4 11.0 0.058 0.0 HOH
 2.890
 OE1
 O
1isn 1 P46662 99.38 0.0 X-RAY
 2002-04-03 GLU A:168 A:185 7.0 0.037 H -57.3 -29.9 7.0 0.037 0.0
4zrj 1 P35240 100.0 0.0 X-RAY
 2015-06-17 GLU A:185 A:185 27.0 0.142 H -63.8 -35.0 27.0 0.142 0.0 HOH
 6.857
 O
 O
4zri 1 P35240 100.0 0.0 X-RAY
 2015-06-17 GLU A:189 A:185 23.0 0.121 H -57.7 -28.3 23.0 0.121 0.0
GLU B:189 B:185 21.0 NA H -55.2 -46.7 NA NA NA
4zrk 1 P46662 99.38 0.0 X-RAY
 2015-06-17 GLU A:189 A:185 18.0 0.095 H -70.1 -31.1 18.0 0.095 0.0
GLU B:189 B:185 33.0 0.174 H -68.0 -26.8 NA NA NA
GLU C:189 C:185 23.0 0.121 H -68.6 -28.6 NA NA NA
GLU D:189 D:185 35.0 0.184 H -67.9 -25.3 NA NA NA
1h4r 1 P35240 100.0 0.0 X-RAY
 2002-01-16 GLU A:186 A:185 15.0 0.079 H -58.6 -39.5 15.0 0.079 0.0 HOH
 2.836
 OE1
 O
GLU B:186 B:185 24.0 0.126 H -61.2 -41.5 24.0 0.126 0.0 HOH
 2.518
 OE2
 O
4p7i 1 P46662 99.36 0.0 X-RAY
 2014-04-09 GLU A:189 A:185 13.0 0.068 H -60.9 -44.0 13.0 0.068 0.0
GLU B:189 B:185 11.0 0.058 H -73.2 -31.9 NA NA NA
3u8z 1 P35240 100.0 0.0 X-RAY
 2011-11-02 GLU A:173 A:185 108.0 0.568 H -65.4 -42.2 93.0 0.489 0.079 C:P35240:0.079
 HOH
 4.704
 O
 O
GLU B:173 B:185 101.0 0.532 H -64.6 -42.3 NA NA NA
GLU C:173 C:185 111.0 0.584 H -64.6 -43.0 93.0 0.489 0.095 A:P35240:0.095
 HOH
 2.973
 OE1
 O
GLU D:173 NA:NA DO NA DO DO DO NA NA NA
3wa0 1 P46662 99.32 0.0 X-RAY
 2014-05-28 GLU A:172 A:185 16.0 0.084 H -63.1 -39.4 16.0 0.084 0.0 HOH
 7.642
 OE1
 O
GLU B:172 B:185 13.0 0.068 H -60.8 -39.3 NA NA NA
GLU C:172 C:185 16.0 0.084 H -58.8 -38.9 NA NA NA
GLU D:172 D:185 20.0 0.105 H -60.2 -40.8 NA NA NA
GLU E:172 E:185 22.0 0.116 H -63.0 -35.4 NA NA NA
GLU F:172 F:185 17.0 0.089 H -59.5 -46.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p35240-f1 1 P35240 100.0 0.0 GLU A:185 A:185 22.0 0.116 H -58.3 -43.7