Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 30051642 . C A CCDS13861.1:NM_000268.3:c.576taC>taA_NP_000259.1:p.192Y>* Homo sapiens neurofibromin 2 (NF2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6cds 1 P35240 99.71 0.0 X-RAY
 2018-07-18 TYR A:192 A:192 0.0 0.0 H -52.0 -41.3 0.0 0.0 0.0
TYR B:192 B:192 0.0 0.0 H -49.1 -46.1 NA NA NA
7lwh 1 P35240 99.41 0.0 X-RAY
 2021-08-11 TYR A:192 A:192 0.0 0.0 H -59.4 -43.4 0.0 0.0 0.0 HOH
 2.832
 O
 O
1isn 1 P46662 99.38 0.0 X-RAY
 2002-04-03 TYR A:175 A:192 0.0 0.0 H -43.6 -37.0 0.0 0.0 0.0
4zrj 1 P35240 100.0 0.0 X-RAY
 2015-06-17 TYR A:192 A:192 0.0 0.0 H -47.5 -50.9 0.0 0.0 0.0 HOH
 2.902
 O
 O
4zri 1 P35240 100.0 0.0 X-RAY
 2015-06-17 TYR A:196 A:192 0.0 0.0 H -47.4 -46.4 0.0 0.0 0.0
TYR B:196 B:192 0.0 0.0 H -51.0 -50.1 NA NA NA
4zrk 1 P46662 99.38 0.0 X-RAY
 2015-06-17 TYR A:196 A:192 0.0 0.0 H -53.0 -46.9 0.0 0.0 0.0
TYR B:196 B:192 0.0 0.0 H -53.0 -47.1 NA NA NA
TYR C:196 C:192 0.0 0.0 H -53.0 -45.5 NA NA NA
TYR D:196 D:192 0.0 0.0 H -52.4 -47.0 NA NA NA
1h4r 1 P35240 100.0 0.0 X-RAY
 2002-01-16 TYR A:193 A:192 0.0 0.0 H -55.1 -43.3 0.0 0.0 0.0 SO4
HOH
 6.724
2.920
 O
O
 O3
O
TYR B:193 B:192 0.0 0.0 H -53.0 -43.9 0.0 0.0 0.0 SO4
SO4
HOH
 9.515
6.615
2.785
 C
O
O
 O2
O3
O
4p7i 1 P46662 99.36 0.0 X-RAY
 2014-04-09 TYR A:196 A:192 0.0 0.0 H -50.0 -46.1 0.0 0.0 0.0
TYR B:196 B:192 0.0 0.0 H -53.7 -50.8 NA NA NA
3u8z 1 P35240 100.0 0.0 X-RAY
 2011-11-02 TYR A:180 A:192 141.0 0.613 H -56.0 -51.2 53.0 0.23 0.383 C:P35240:0.383
 HOH
 2.790
 OH
 O
TYR B:180 B:192 135.0 0.587 H -56.4 -50.6 NA NA NA
TYR C:180 C:192 165.0 0.717 H -56.6 -49.7 71.0 0.309 0.408 A:P35240:0.409
 HOH
 2.941
 O
 O
TYR D:180 NA:NA DO NA DO DO DO NA NA NA
3wa0 1 P46662 99.32 0.0 X-RAY
 2014-05-28 TYR A:179 A:192 0.0 0.0 H -52.9 -46.1 0.0 0.0 0.0 HOH
 6.306
 N
 O
TYR B:179 B:192 0.0 0.0 H -48.7 -45.4 NA NA NA
TYR C:179 C:192 0.0 0.0 H -50.7 -46.3 NA NA NA
TYR D:179 D:192 0.0 0.0 H -55.2 -42.4 NA NA NA
TYR E:179 E:192 0.0 0.0 H -48.2 -49.1 NA NA NA
TYR F:179 F:192 0.0 0.0 H -52.2 -45.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p35240-f1 1 P35240 100.0 0.0 TYR A:192 A:192 0.0 0.0 H -59.2 -40.6