Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 30057197 . A C CCDS13861.1:NM_000268.3:c.679Aaa>Caa_NP_000259.1:p.227K>Q Homo sapiens neurofibromin 2 (NF2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6cds 1 P35240 99.71 0.0 X-RAY
 2018-07-18 LYS A:227 A:227 173.0 0.865 T -53.7 -37.4 173.0 0.865 0.0 HOH
 3.126
 CD
 O
LYS B:227 B:227 171.0 0.855 T -50.7 -37.2 NA NA NA
7lwh 1 P35240 99.41 0.0 X-RAY
 2021-08-11 LYS A:227 A:227 112.0 0.56 T -66.9 -19.8 112.0 0.56 0.0 HOH
 2.772
 O
 O
1isn 1 P46662 99.38 0.0 X-RAY
 2002-04-03 LYS A:210 A:227 142.0 0.71 T -55.0 -9.9 142.0 0.71 0.0
4zrj 1 P35240 100.0 0.0 X-RAY
 2015-06-17 LYS A:227 A:227 148.0 0.74 S -58.9 -42.6 123.0 0.615 0.125 B:P35240:0.125
 HOH
 3.172
 N
 O
4zri 1 P35240 100.0 0.0 X-RAY
 2015-06-17 LYS A:231 A:227 92.0 NA T -57.2 -45.1 92.0 NA NA
LYS B:231 B:227 106.0 0.53 T -69.9 -46.5 NA NA NA
4zrk 1 P46662 99.38 0.0 X-RAY
 2015-06-17 LYS A:231 A:227 122.0 0.61 T -63.9 -25.4 122.0 0.61 0.0 HOH
 4.750
 CB
 O
LYS B:231 B:227 95.0 NA T -62.5 -29.9 NA NA NA
LYS C:231 C:227 115.0 0.575 T -63.3 -31.1 NA NA NA
LYS D:231 D:227 98.0 0.49 T -61.7 -30.2 NA NA NA
1h4r 1 P35240 100.0 0.0 X-RAY
 2002-01-16 LYS A:228 A:227 107.0 0.535 T -70.8 -13.1 107.0 0.535 0.0 HOH
 2.898
 N
 O
LYS B:228 B:227 109.0 0.545 T -64.8 -20.9 109.0 0.545 0.0 HOH
 2.808
 N
 O
4p7i 1 P46662 99.36 0.0 X-RAY
 2014-04-09 LYS A:231 A:227 110.0 0.55 T -63.6 -14.8 110.0 0.55 0.0 HOH
 3.839
 N
 O
LYS B:231 B:227 122.0 0.61 T -75.0 -14.8 NA NA NA
3u8z 1 P35240 100.0 0.0 X-RAY
 2011-11-02 LYS A:215 A:227 146.0 0.73 T -64.8 -28.6 146.0 0.73 0.0 HOH
 3.745
 N
 O
LYS B:215 B:227 145.0 0.725 T -61.9 -26.0 NA NA NA
LYS C:215 C:227 146.0 0.73 T -62.0 -26.2 146.0 0.73 0.0 HOH
 4.436
 CG
 O
LYS D:215 D:227 122.0 0.61 T -59.2 -28.4 NA NA NA
3wa0 1 P46662 99.32 0.0 X-RAY
 2014-05-28 LYS A:214 A:227 108.0 0.54 T -53.4 -47.4 108.0 0.54 0.0 HOH
 4.950
 NZ
 O
LYS B:214 B:227 117.0 0.585 T -64.5 -35.6 NA NA NA
LYS C:214 C:227 140.0 0.7 T -71.0 -29.0 NA NA NA
LYS D:214 D:227 149.0 0.745 T -54.7 -53.3 NA NA NA
LYS E:214 E:227 184.0 0.92 T -51.9 -50.6 NA NA NA
LYS F:214 F:227 102.0 0.51 T -56.8 -50.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p35240-f1 1 P35240 100.0 0.0 LYS A:227 A:227 115.0 0.575 T -64.2 -29.6